We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
GET1
HPA
RESOURCES
  • TISSUE
  • BRAIN
  • SINGLE CELL
  • SUBCELLULAR
  • CANCER
  • BLOOD
  • CELL LINE
  • STRUCTURE
  • INTERACTION
ABOUT
  • INTRODUCTION
  • HISTORY
  • ORGANIZATION
  • PUBLICATIONS
  • ACKNOWLEDGMENTS
  • CONTACT
NEWS
  • NEWS ARTICLES
  • PRESS ROOM
LEARN
  • DICTIONARY
  • PROTEIN CLASSES
  • PROTEIN EVIDENCE
  • METHODS
  • EDUCATIONAL VIDEOS
DATA
  • DOWNLOADABLE DATA
  • PUBLICATION DATA
  • RELEASE HISTORY
HELP
  • HELP & FAQ
  • ANTIBODY SUBMISSION
  • ANTIBODY AVAILABILITY
  • DISCLAIMER
  • PRIVACY STATEMENT
  • LICENCE & CITATION
Fields »
Search result

 
Field
All
Term
Gene name
Class
Blood group antigen proteins
Subclass
 
Category
 
Keyword
Chromosome
External id
Tissue
 
Cell type
 
Expression
Antibody panel
 
Tissue
 
Main location
Patient ID
Annotation
Tissue
Category
Tau score
Cluster
Reliability
Brain region
Category
Tau score
Brain region
Category
Tau score
Brain region
Category
Tau score
Cluster
Reliability
Tissue
 
Cell type
Enrichment
Cell type
Category
Tau score
Cell type group
Category
Tau score
Cell type
Category
Tau score
Cell type
Category
Tau score
Cell lineage
Category
Tau score
Cluster
Cluster
Location
Searches
Location
Cell line
Class
Type
Phase
Reliability
Cancer
Prognosis
Cancer
Category
Cancer
Category
Tau score
Cluster
Variants
Interacting gene (ensg_id)
Type
Number of interactions
Pathway
ipTM
Category
Category
Category
Category
Validation
Validation
Validation
Validation
Antibodies
Yes
Data type
Column
Gene


                              • SPECIFICITY
                              • DISTRIBUTION
                              • EXPRESSION
                              • SPECIFICITY
                              • DISTRIBUTION
                              • EXPRESSION
                              • SPECIFICITY
                              • DISTRIBUTION
                              • EXPRESSION
                              • SPECIFICITY
                              • DISTRIBUTION
                              • EXPRESSION
                                  • SPECIFICITY
                                  • DISTRIBUTION
                                  • EXPRESSION
                                  • SPECIFICITY
                                  • DISTRIBUTION
                                  • EXPRESSION
                                  • SPECIFICITY
                                  • DISTRIBUTION
                                  • EXPRESSION
                                  • SPECIFICITY
                                  • DISTRIBUTION
                                  • EXPRESSION
                                  • SPECIFICITY
                                  • DISTRIBUTION
                                  • EXPRESSION
                                  • RELIABILITY
                                  • SUBCELLULAR VARIATION
                                  • MULTILOCALIZATION
                                  • OTHER
                                  • SPECIFICITY
                                  • DISTRIBUTION
                                  • EXPRESSION
                                  • SPECIFICITY
                                  • DISTRIBUTION
                                  • EXPRESSION
                                  • Check all
                                  • Uncheck all
                                          • SUMMARY

                                          • TISSUE

                                          • BRAIN

                                          • SINGLE CELL

                                          • SUBCELL

                                          • CANCER

                                          • BLOOD

                                          • CELL LINE

                                          • STRUCTURE

                                          • INTERACTION

                                          • GET1
                                          SINGLE CELL KIDNEY Show tissue menu
                                          ADIPOSE TISSUE ADRENAL GLAND BLOOD BONE MARROW BRAIN BREAST COLON ENDOMETRIUM EPIDIDYMIS ESOPHAGUS
                                          EYE FALLOPIAN TUBE HEART MUSCLE KIDNEY LIVER LUNG LYMPH NODE OVARY PANCREAS PITUITARY GLAND
                                          PLACENTA PROSTATE RECTUM SALIVARY GLAND SKELETAL MUSCLE SKIN SMALL INTESTINE SPLEEN STOMACH TESTIS
                                          THYMUS THYROID GLAND TONGUE URINARY BLADDER VASCULATURE
                                          Single cell type
                                          Tabula sapiens
                                          Tissue cell type
                                          SINGLE CELL TYPE TABULA SAPIENS TISSUE CELL TYPE CELL TYPE MARKERS
                                          Cell types
                                          Specialized epithelial cells
                                          Mesenchymal cells
                                          Endothelial and mural cells
                                          Blood and immune cells
                                          Muscle cells
                                          Glial cells
                                          Methods
                                          Cell type enrichment
                                          Kidney
                                          Methods
                                          KIDNEY DETAIL SUMMARY
                                          Renal collecting duct intercalated cellsRenal collecting duct principal cellsRenal connecting tubule cellsPodocytesProximal tubule cellsLoop of henle epithelial cellsPapillary tip epithelial cellsDistal convoluted tubule cellsVascular endothelial cellsLymphatic endothelial cellsPericytesVascular smooth muscle cellsFibroblastsMacrophagesT-cellsB-cellsNK-cells010203040506070nCPMSpecialized epithelial cellsEndothelial and mural cellsMesenchymal cellsBlood and immune cells
                                          SINGLE CELL TYPE - KIDNEYi

                                          RNA expression in the single cell type clusters identified in this tissue visualized by a UMAP plot (top) and a bar chart (bottom).

                                          - UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart below. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. The cells are colored according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%)

                                          - The LEGEND shows RNA expression (nTPM) in each cell type cluster. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

                                          Cell type color
                                          Cluster color
                                          Colored according to cell type group
                                          Colored according to clusters
                                          Read count filter: 0
                                          Cluster filter:
                                           
                                          Cluster Cell type Expression (nCPM)
                                          0 70
                                          c-0 Proximal tubule S1/2
                                          c-1 Thick ascending limb
                                          c-2 Collecting duct principal c...
                                          c-3 Fibroblasts
                                          c-4 Proximal tubule S1/2 (injur
                                          c-5 Distal convoluted tubule ce
                                          c-6 Collecting duct intercalate...
                                          c-7 Connecting tubule cells
                                          c-8 Thin descending limb
                                          c-9 Thick ascending limb (dedif...
                                          c-10 Collecting duct principal c...
                                          c-11 Ascending vasa recta ECs
                                          c-12 Peritubular capillary ECs
                                          c-13 Ascending thin limb
                                          c-14 Proximal tubule S3
                                          c-15 Myofibroblasts
                                          c-16 Loop of henle ECs (dediffer...
                                          c-17 Proximal tubule S1/2 (injur
                                          c-18 Descending vasa recta ECs
                                          c-19 Thick ascending limb (Macul...
                                          c-20 Macrophages
                                          c-21 Pericytes
                                          c-22 Podocytes
                                          c-23 Glomerular capillary ECs
                                          c-24 Papillary tip epithelial ce
                                          c-25 Collecting duct intercalate...
                                          c-26 Thick ascending limb (dedif...
                                          c-27 T-cells (CD4+)
                                          c-28 Parietal epithelial cells
                                          c-29 Macrophages
                                          c-30 Collecting duct principal c...
                                          c-31 Activated fibroblasts
                                          c-32 Vascular smooth muscle cell
                                          c-33 Smooth muscle cells
                                          c-34 T-cells (CD8+)
                                          c-35 Arteriole ECs
                                          c-36 Mesangial cells
                                          c-37 B-cells
                                          c-38 Non classical Monocyte
                                          c-39 NK cells
                                          c-40 Lymphatic endothelial cells
                                          c-41 Plasma cells
                                          c-42 Mast cells
                                          c-43 Conventional dendritic cell
                                          c-44 Plasmacytoid DCs
                                          c-45 Schwann cells
                                          c-46 Lymphoid DCs
                                          c-47 Neutrophils
                                          c-48 Adipocytes
                                          SINGLE CELL TYPE TABULA SAPIENS - KIDNEYi

                                          RNA expression in the single cell type clusters identified in this tissue visualized by a UMAP plot and a bar chart. This window shows single cell expression data generated by the https://tabula-sapiens.sf.czbiohub.org/about#consortium, that also offers UMAP visualization and cell type clusters for each tissue sample: https://tabula-sapiens.sf.czbiohub.org/organs, here integrate offering easy comparison to the HPA cluster method of single cell types.

                                          • UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart below. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. The cells are colored according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%)

                                          • The LEGEND shows RNA expression (nTPM) in each cell type cluster. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

                                          Cell type color
                                          Cluster color
                                          Colored according to cell type group
                                          Colored according to clusters
                                          Read count filter: 0
                                           
                                          Cluster Cell type Expression (nCPM)
                                          0 80
                                          c-0 Kidney epithelial cell
                                          c-1 B cell
                                          c-2 Cd8-positive, alpha-beta t ...
                                          c-3 Endothelial cell
                                          c-4 Macrophage
                                          c-5 Nk cell
                                          c-6 Cd4-positive helper t cell
                                          TISSUE CELL TYPE - KIDNEYi

                                          The plot below shows the enrichment prediction score for each cell type profiled in the tissue. This score is the mean correlation between the selected gene and the 3 reference transcripts selected to represent each cell type profiled within the tissue. An enlarged symbol indicates classification of the gene as cell type enriched in the corresponding cell type. Hover the mouse pointer over the symbols or cell type names to see the mean correlation values.

                                          Category
                                          Alphabetical
                                          Enrichment
                                          PodocytesProximal tubular cells_1Proximal tubular cells_2Ascending Loop of Henle cellsIntercalated cellsEndothelial cellsFibroblastsMacrophagesT-cellsPlasma cells0.30.40.50.60.70.80.91.0EnrichmentSpecialized epithelial cellsGlandular epithelial cellsEndothelial and mural cellsMesenchymal cellsBlood and immune cells
                                          CELL TYPE MARKERSi

                                          The heatmap in this section shows expression of the currently selected gene (on top) and well-known cell type markers in the different single cell type clusters of this tissue. The panel on the left shows which cell type each marker is associated with. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.

                                          Hover the mouse-pointer over the individual data points (squares) to see nTPM level and Z-score. Clicking on a gene name redirects to the corresponding gene page.

                                          Z-score is when you normalize a variable such that the standard deviation is 1 and the mean is 0. Thus, all the genes are easier to compare, as they have the same center and distribution.

                                          SINGLE CELL TYPE
                                          TABULA SAPIENS
                                          TISSUE CELL TYPE
                                          Max-norm
                                          Z-score
                                          Fraction of highest expression (≥1 nTPM)
                                          log2(nTPM+1) z-score
                                          GET1S100BCDH19L1CAMATP6V0A4ATP6V1B1SLC26A7SLC4A1SLC26A4SLC4A9AQP2FXYD4SLC14A2CALB1HSD11B2SLC8A1TRPV5NPHS2PTPRQWT1LRP2PRODH2SLC22A6SLC7A13SLC12A1UMODNOS1SLC44A5ADGRL3AQP1CLDN10PROX1GPX2TP63SLC12A3TRPM6ACTG2DESMYH11PECAM1VWFPLVAPEDN1SERPINE2EMCNHECW2ITGA8SLCO2A1CD36RGCCLYVE1PDGFRBRGS5STEAP4ACTA2CNN1ADIPOQFABP4LIPEPLIN1COL1A1DCNFBLN2PDGFRAFOSJUNCPA3TPSAB1TPSB2CEACAM8CSF3RCXCR2FCGR3BFCN1IL1BS100A8S100A9VCANCD14FCGR3AC1QBC1QCF13A1FOLR2CD3DCD3GCD4CD8AIL7RBANK1CD19MS4A1DERL3IGHA1CLEC9AIRF8CCR7LAMP3CLEC4CIL3RAIRF7GZMANKG7PRF1ALDH1A2CFHVCAM1Proximal tubule cells c-0Loop of henle epithelial cells c-1Renal collecting duct principal cells c-2Fibroblasts c-3Proximal tubule cells c-4Distal convoluted tubule cells c-5Renal collecting duct intercalated cells c-6Renal connecting tubule cells c-7Loop of henle epithelial cells c-8Loop of henle epithelial cells c-9Renal collecting duct principal cells c-10Vascular endothelial cells c-11Vascular endothelial cells c-12Loop of henle epithelial cells c-13Proximal tubule cells c-14Fibroblasts c-15Loop of henle epithelial cells c-16Proximal tubule cells c-17Vascular endothelial cells c-18Loop of henle epithelial cells c-19Macrophages c-20Pericytes c-21Podocytes c-22Vascular endothelial cells c-23Papillary tip epithelial cells c-24Renal collecting duct intercalated cells c-25Loop of henle epithelial cells c-26T-cells c-27Parietal epithelial cells c-28Macrophages c-29Renal collecting duct principal cells c-30Fibroblasts c-31Vascular smooth muscle cells c-32Smooth muscle cells c-33T-cells c-34Vascular endothelial cells c-35Mesangial cells c-36B-cells c-37Monocytes c-38NK-cells c-39Lymphatic endothelial cells c-40Plasma cells c-41Mast cells c-42CDC c-43PDCs c-44Schwann cells c-45CDC c-46Neutrophils c-47Adipocytes c-48Current geneSchwann cellsRenal collecting duct intercalated cellsRenal collecting duct principal cellsRenal connecting tubule cellsPodocytesProximal tubule cellsLoop of henle epithelial cellsPapillary tip epithelial cellsDistal convoluted tubule cellsSmooth muscle cellsVascular endothelial cellsLymphatic endothelial cellsPericytesVascular smooth muscle cellsAdipocytesFibroblastsMast cellsNeutrophilsMonocytesMacrophagesT-cellsB-cellsPlasma cellsCDCPDCsNK-cellsParietal epithelial cells00.250.50.751-4-2024
                                          Max-norm
                                          Z-score
                                          Fraction of highest expression (≥1 nTPM)
                                          log2(nTPM+1) z-score
                                          GET1S100BCDH19L1CAMATP6V0A4ATP6V1B1SLC26A7SLC4A1SLC26A4SLC4A9AQP2FXYD4SLC14A2CALB1HSD11B2SLC8A1TRPV5NPHS2PTPRQWT1LRP2PRODH2SLC22A6SLC7A13SLC12A1UMODNOS1SLC44A5ADGRL3AQP1CLDN10PROX1GPX2TP63SLC12A3TRPM6ACTG2DESMYH11PECAM1VWFPLVAPEDN1SERPINE2EMCNHECW2ITGA8SLCO2A1CD36RGCCLYVE1PDGFRBRGS5STEAP4ACTA2CNN1ADIPOQFABP4LIPEPLIN1COL1A1DCNFBLN2PDGFRAFOSJUNCPA3TPSAB1TPSB2CEACAM8CSF3RCXCR2FCGR3BFCN1IL1BS100A8S100A9VCANCD14FCGR3AC1QBC1QCF13A1FOLR2CD3DCD3GCD4CD8AIL7RBANK1CD19MS4A1DERL3IGHA1CLEC9AIRF8CCR7LAMP3CLEC4CIL3RAIRF7GZMANKG7PRF1ALDH1A2CFHVCAM1Kidney epithelial cell c-0B cell c-1Cd8-positive, alpha-beta t cell c-2Endothelial cell c-3Macrophage c-4Nk cell c-5Cd4-positive helper t cell c-6Current geneSchwann cellsRenal collecting duct intercalated cellsRenal collecting duct principal cellsRenal connecting tubule cellsPodocytesProximal tubule cellsLoop of henle epithelial cellsPapillary tip epithelial cellsDistal convoluted tubule cellsSmooth muscle cellsVascular endothelial cellsLymphatic endothelial cellsPericytesVascular smooth muscle cellsAdipocytesFibroblastsMast cellsNeutrophilsMonocytesMacrophagesT-cellsB-cellsPlasma cellsCDCPDCsNK-cellsParietal epithelial cells00.250.50.751-4-2024
                                          GET1 NPHS1NPHS2PTPROACE2ANPEPLRP2AGMATASPDHMSRACLDN19NRKSLC12A1ATP6V1G3HEPACAM2SLC4A9ADGRL4ECSCRERGDCNDKK3FBLN5C1QACD163VSIG4CD6CD96TRBC2IGHG1IGKCJCHAINNPHS1NPHS2PTPROACE2ANPEPLRP2AGMATASPDHMSRACLDN19NRKSLC12A1ATP6V1G3HEPACAM2SLC4A9ADGRL4ECSCRERGDCNDKK3FBLN5C1QACD163VSIG4CD6CD96TRBC2IGHG1IGKCJCHAINCurrent genePodocytesProximal tubular cells_1Proximal tubular cells_2Ascending Loop of Henle cellsIntercalated cellsEndothelial cellsFibroblastsMacrophagesT-cellsPlasma cells<00.250.50.751
                                           

                                          Contact

                                          • NEWS ARTICLES
                                          • PRESS ROOM

                                          The Project

                                          • INTRODUCTION
                                          • ORGANIZATION
                                          • PUBLICATIONS

                                          The Human Protein Atlas

                                          • DOWNLOADABLE DATA
                                          • LICENCE & CITATION
                                          • HELP & FAQ
                                          The Human Protein Atlas project is funded
                                          by the Knut & Alice Wallenberg Foundation.

                                          contact@proteinatlas.org