The Single Cell Resource

The Single Cell resource of the Human Protein Atlas presents comprehensive data on gene expression across various human tissues and cell types, utilizing single cell RNA sequencing (scRNAseq), cell sorting, single nuclei RNA sequencing (snRNAseq), and bulk RNAseq correlation analyses. The resource provides insights into mRNA and protein expression patterns, gene specificity, and expression clustering with single cell types, immune cells and brain single nuclei. The Single Cell Resource includes four main datasets:

• The Single cell type section, providing the expression profiles across 81 cell types from 31 human tissues, and cell type specificity based on gene expression.
• The Tissue cell type section, providing the predicted cell-type expression specificity based on bulk RNAseq
• The Single nuclei brain section, providing more details regarding cell type specificity within the brain, based on single nuclei RNAseq
• The Immune cell section, providing expression comparison between sorted immune cells

Learn more about each of these four parts down below, and explore the details of each dataset, or serach for a gene and browse the expression details side by side across the different datasets on the gene summary pages. More information about the content, the generation and analysis of the data in this resource can be found under respective link or here for single cell type, tissue cell type, single nuclei brain and immune cell. Additionally, each focused section is based on different datasets, see more details here for single cell type, tissue cell type (using GTEx RNAseq data), single nuclei brain and immune cell.