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VPS37B
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                                          • SUMMARY

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                                          • VPS37B
                                          TISSUE PRIMARY DATA CERVIX Show tissue menu
                                          ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BLOOD VESSEL BONE MARROW BREAST BRONCHUS CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON
                                          DUODENUM ENDOMETRIUM EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MIDBRAIN
                                          NASOPHARYNX ORAL MUCOSA OVARY PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN
                                          SMALL INTESTINE SMOOTH MUSCLE SOFT TISSUE SPINAL CORD SPLEEN STOMACH TESTIS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA
                                          ANTIBODIES
                                          AND
                                          VALIDATION
                                          Dictionary
                                          Cervix
                                          Tissue proteome
                                          Cervix
                                          Tissue methods
                                          CERVIX - Expression summary
                                          Protein expression
                                          Cervixi

                                          On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

                                          h
                                          m
                                          l
                                          n
                                          Glandular cells: Medium
                                          Squamous epithelial cells: Medium
                                          RNA expressioni

                                          A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

                                          Scroll down to view mRNA expression data in more detail.

                                          Consensus:16.2 nTPM
                                          HPA:9.5 nTPM
                                          GTEx:16.2 nTPM
                                          FANTOM5:42.1 Scaled Tags Per Million

                                          CERVIX - Antibody stainingi

                                          Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells. Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.

                                          Ascending and descending describe two types of gradient, based on difference in staining intensity between enterocytes in crypts and apical enterocytes.

                                          Ascending - the staining intensity is stronger in apical enterocytes (towards the lumen) compared to enterocytes in the crypts (gland based)

                                          Descending - the staining is weaker in apical enterocytes compared to enterocytes in crypts

                                          Antibody HPA038217Antibody HPA038218
                                          Glandular cells MediumMedium
                                          Squamous epithelial cells MediumLow





                                          CERVIX - HPA RNA-seqi

                                          The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.

                                          Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.

                                          Average nTPMi

                                          Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

                                          9.5
                                          overview
                                          Female, age 44
                                          Cervix sample 374
                                          nTPM: 8.4
                                          Cell types%
                                          Glandular cells:
                                          10

                                          Squamous epithelial cells:
                                          5

                                          Smooth muscle cells:
                                          65

                                          Other cell types:
                                          20

                                          overview
                                          Female, age 53
                                          Cervix sample 383
                                          nTPM: 10.5
                                          Cell types%
                                          Glandular cells:
                                          10

                                          Squamous epithelial cells:
                                          5

                                          Smooth muscle cells:
                                          65

                                          Other cell types:
                                          20


                                          CERVIX - GTEx RNA-seqi

                                          RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

                                          Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

                                          Max subtype nTPMi

                                          Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

                                          16.2
                                          GTEx sample id Sample description nTPM
                                          11.313.022.47.532.1051015202530
                                          11.313.022.47.532.1051015202530
                                          Cervix - Ectocervix
                                          Average nTPM: 16.2
                                          Samples: 24

                                          Max nTPM: 32.1
                                          Min nTPM: 7.5
                                          Std nTPM: 6.7
                                          Median nTPM: 13.0
                                          GTEX-PWN1-2126-SM-H6Q83 40-49 years, female 32.1
                                          GTEX-R55G-1826-SM-HL9TM 40-49 years, female 27.1
                                          GTEX-TML8-0826-SM-GNIN4 40-49 years, female 27.1
                                          GTEX-SN8G-2126-SM-GPI8G 50-59 years, female 25.3
                                          GTEX-Q734-1526-SM-GQ1EE 40-49 years, female 23.4
                                          GTEX-P4QT-2126-SM-H6Q7H 50-59 years, female 23.3
                                          GTEX-T5JW-0726-SM-4DM6D 20-29 years, female 22.1
                                          GTEX-T6MO-1326-SM-H7OGZ 40-49 years, female 18.3
                                          GTEX-T2IS-2326-SM-HL9TW 20-29 years, female 15.9
                                          GTEX-QDT8-2626-SM-GPI86 30-39 years, female 15.8
                                          GTEX-PX3G-2226-SM-GOQZQ 20-29 years, female 14.3
                                          GTEX-S4UY-1426-SM-4AD6Y 40-49 years, female 13.3
                                          GTEX-S341-1126-SM-4AD6T 40-49 years, female 12.7
                                          GTEX-QVJO-2726-SM-GQ1CG 60-69 years, female 12.6
                                          GTEX-Q2AG-2326-SM-EZ6KY 40-49 years, female 12.4
                                          GTEX-POMQ-1526-SM-HL9TL 20-29 years, female 12.0
                                          GTEX-P78B-2326-SM-EZ6KO 40-49 years, female 11.9
                                          GTEX-TMMY-2026-SM-GPI8C 40-49 years, female 11.4
                                          GTEX-N7MT-0826-SM-EV794 60-69 years, female 10.9
                                          GTEX-OHPL-2126-SM-GPRYM 60-69 years, female 10.0
                                          GTEX-QCQG-1026-SM-GOQYG 50-59 years, female 9.8
                                          GTEX-P4PP-2226-SM-GRR1L 30-39 years, female 9.5
                                          GTEX-TSE9-2826-SM-4DXTF 60-69 years, female 9.3
                                          GTEX-S32W-1526-SM-4AD6Z 50-59 years, female 7.5
                                          Show allShow less
                                          10.312.414.88.018.2024681012141618
                                          10.312.414.88.018.2024681012141618
                                          Cervix - Endocervix
                                          Average nTPM: 12.3
                                          Samples: 23

                                          Max nTPM: 18.2
                                          Min nTPM: 8.0
                                          Std nTPM: 2.6
                                          Median nTPM: 12.4
                                          GTEX-P78B-2426-SM-EWRM2 40-49 years, female 18.2
                                          GTEX-PX3G-2126-SM-HL9TS 20-29 years, female 15.3
                                          GTEX-T6MO-1426-SM-4DM73 40-49 years, female 15.3
                                          GTEX-T2IS-2426-SM-HL9U4 20-29 years, female 15.1
                                          GTEX-RU1J-1126-SM-GPRWI 20-29 years, female 15.0
                                          GTEX-QVJO-2826-SM-F21IP 60-69 years, female 14.8
                                          GTEX-S341-1326-SM-4AD72 40-49 years, female 14.8
                                          GTEX-PWN1-2226-SM-HAUZA 40-49 years, female 13.6
                                          GTEX-N7MT-0926-SM-HAUYT 60-69 years, female 13.5
                                          GTEX-PLZ4-2226-SM-EZ6KS 50-59 years, female 13.0
                                          GTEX-TML8-0726-SM-4DXTT 40-49 years, female 12.8
                                          GTEX-T5JW-0826-SM-EYYVD 20-29 years, female 12.4
                                          GTEX-S4UY-1526-SM-GNTAF 40-49 years, female 11.8
                                          GTEX-ZPIC-1326-SM-DO91Y 40-49 years, female 11.3
                                          GTEX-OHPL-2226-SM-G9ER8 60-69 years, female 10.9
                                          GTEX-Q734-1726-SM-HL9TR 40-49 years, female 10.8
                                          GTEX-OHPK-2226-SM-HL9TP 50-59 years, female 10.7
                                          GTEX-QCQG-1126-SM-GOQYH 50-59 years, female 9.9
                                          GTEX-RWS6-1626-SM-GOQYA 60-69 years, female 9.4
                                          GTEX-P4PP-2126-SM-H7OF1 30-39 years, female 9.3
                                          GTEX-S32W-1626-SM-4AD6G 50-59 years, female 9.0
                                          GTEX-OHPN-2226-SM-E9TI7 60-69 years, female 8.0
                                          GTEX-TSE9-2726-SM-4DXSQ 60-69 years, female 8.0
                                          Show allShow less

                                          CERVIX - FANTOM5 CAGEi

                                          RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

                                          Max subtype Scaled Tags Per Millioni

                                          Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

                                          42.1
                                          FANTOM5 sample id Sample description Scaled Tags Per Million
                                          Cervix
                                          Scaled Tags Per Million: 42.1
                                          FF:10013-101C4 40,46,57,65 years, female 42.1

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