CEREBRAL CORTEX - Expression summary
Protein expression
Cerebral cortexi
h
m
l
n
Endothelial cells: Medium
Glial cells: Low
Neuronal cells: Medium
Neuropil: Medium
RNA expressioni
Consensus:20.5 nTPM
HPA:14.1 nTPM
HPA Brain:40.8 nTPM
HPA PFC Brain:17.7 nTPM
GTEx:20.5 nTPM
FANTOM5:49.8 Scaled Tags Per Million
Pig:17.6 nTPM
Mouse:21.5 nTPM
Allen mouse:16.7 Expression energy
BRAIN - SINGLE CELL RNA EXPRESSION
Brain excitatory neuronsBrain inhibitory neuronsOther brain neuronsAstrocytesBergmann gliaOligodendrocyte progenitor cellsOligodendrocytesMicrogliaEpendymal cellsChoroid plexus epithelial cellsVascular endothelial cellsPericytesVascular smooth muscle cellsFibroblastsMonocytesMacrophagesT-cellsB-cellsNK-cells050100150200nCPM

CEREBRAL CORTEX - Antibody stainingi
Antibody HPA038217Antibody HPA038218
Endothelial cells MediumNot detected
Glial cells LowLow
Neuronal cells MediumMedium
Neuropil MediumMedium





CEREBRAL CORTEX - HPA RNA-seqi
Average nTPMi 14.1
N/A
Male, age 5
Cerebral cortex sample 48
nTPM: 13.9
overview
Female, age 40
Cerebral cortex sample 105
nTPM: 16
Cell types%
Neuronal cells:
35

Glial cells and endothelial cells:
65
overview
Male, age 70
Cerebral cortex sample 106
nTPM: 12.3
Cell types%
Neuronal cells:
35

Glial cells and endothelial cells:
65

CEREBRAL CORTEX - HPA Brain RNA-seq
Max subtype nTPMi 40.8
Sample id Sample description nTPM
Angular gyrus
nTPM: 26.3
2265 Female, age 91, left hemisphere 33.2
2722 Male, age 61, left hemisphere 29.4
2602 Female, age 94, right hemisphere 27.8
2260 Female, age 72, left hemisphere 27.6
1790 Male, age 76, right hemisphere 26.4
2103 Male, age 75, left hemisphere 23.3
1866 Male, age 76, both hemispheres 22.3
2221 Female, age 67, right hemisphere 20.1
Anterior cingulate cortex, supragenual-dorsal
nTPM: 28.3
2478 Female, age 67, right hemisphere 31.5
2342 Female, age 94, right hemisphere 30.2
2547 Male, age 74, left hemisphere 28.1
2472 Male, age 75, left hemisphere 27.4
1896 Female, age 85, right hemisphere 24.6
Anterior cingulate cortex, supragenual-ventral
nTPM: 29.9
2479 Female, age 67, right hemisphere 33.8
2538 Male, age 75, left hemisphere 31.5
1755 Female, age 94, right hemisphere 28.3
1950 Female, age 85, right hemisphere 28.1
1761 Male, age 74, left hemisphere 27.8
Anterior insular cortex, dorsal
nTPM: 29.6
2001 Male, age 76, right hemisphere 35.5
2235 Female, age 91, right hemisphere 28.3
2670 Male, age 75, left hemisphere 28.1
2506 Female, age 94, right hemisphere 26.3
Anterior insular cortex, ventral
nTPM: 30.3
2507 Female, age 94, left hemisphere 40.5
1852 Male, age 76, left hemisphere 31.5
2757 Male, age 61, right hemisphere 29.1
2596 Male, age 75, left hemisphere 28.9
2262 Female, age 67, right hemisphere 27.9
1925 Female, age 91, left hemisphere 24.0
Area parastriata, inferior
nTPM: 25.7
2421 Female, age 91, left hemisphere 29.5
1758 Female, age 72, right hemisphere 27.7
1789 Male, age 76, right hemisphere 26.4
2268 Male, age 61, right hemisphere 26.1
1760 Female, age 67, left hemisphere 25.4
2234 Male, age 75, left hemisphere 23.2
2509 Female, age 94, left hemisphere 21.8
Area parastriata, parietal
nTPM: 27.9
2236 Female, age 91, left hemisphere 35.3
2680 Female, age 94, right hemisphere 28.7
2233 Male, age 61, right hemisphere 26.0
2420 Male, age 75, left hemisphere 25.6
1785 Male, age 76, right hemisphere 24.0
Area parastriata, superior
nTPM: 37.5
2435 Male, age 61, left hemisphere 87.9
2881 Male, age 76, left hemisphere 36.6
2684 Female, age 67, left hemisphere 28.7
2604 Female, age 94, right hemisphere 26.5
1773 Female, age 91, left hemisphere 22.7
2419 Male, age 75, right hemisphere 22.7
Area parastriata, temporal
nTPM: 26.0
2267 Male, age 61, right hemisphere 27.9
1804 Male, age 76, right hemisphere 26.7
2471 Male, age 75, left hemisphere 26.5
2424 Female, age 67, left hemisphere 25.4
2681 Female, age 94, right hemisphere 23.6
Area striata
nTPM: 29.6
2679 Female, age 94, right hemisphere 38.8
2002 Female, age 91, right hemisphere 31.5
1884 Male, age 76, left hemisphere 29.5
2427 Female, age 91, left hemisphere 28.9
2417 Male, age 61, right hemisphere 24.7
1753 Female, age 72, right hemisphere 24.0
Claustrum
nTPM: 30.4
2645 Female, age 72, unknown 37.8
2292 Female, age 85, both hemispheres 34.1
2196 Female, age 79, unknown 30.6
2284 Female, age 91, both hemispheres 30.5
2568 Male, age 61, both hemispheres 30.2
2491 Male, age 75, both hemispheres 28.9
1956 Male, age 74, unknown 28.7
2198 Male, age 80, both hemispheres 26.6
2392 Female, age 94, both hemispheres 26.0
Frontal eye field
nTPM: 26.1
2761 Female, age 94, left hemisphere 29.1
2441 Male, age 75, left hemisphere 27.8
2543 Male, age 74, left hemisphere 25.4
2147 Male, age 61, left hemisphere 22.0
Frontal operculum
nTPM: 26.9
2781 Female, age 85, right hemisphere 32.4
2348 Male, age 75, left hemisphere 25.6
2030 Male, age 61, right hemisphere 22.6
Fusiform gyrus
nTPM: 32.4
2617 Female, age 94, left hemisphere 43.5
2784 Female, age 85, left hemisphere 40.1
2112 Male, age 80, both hemispheres 32.3
1807 Male, age 76, left hemisphere 31.1
2074 Female, age 91, left hemisphere 27.9
2433 Female, age 72, left hemisphere 27.5
2431 Male, age 75, right hemisphere 24.6
Inferior frontal gyrus, opercular
nTPM: 28.8
2872 Female, age 94, right hemisphere 34.2
2871 Female, age 94, left hemisphere 31.1
2873 Female, age 85, left hemisphere 30.5
2874 Female, age 85, right hemisphere 29.5
2875 Female, age 67, left hemisphere 29.0
2867 Male, age 75, left hemisphere 27.9
2868 Male, age 75, right hemisphere 27.8
2869 Male, age 74, left hemisphere 27.1
2865 Male, age 61, left hemisphere 25.6
2866 Male, age 61, right hemisphere 25.1
Inferior parietal lobule
nTPM: 31.0
2599 Female, age 94, left hemisphere 35.5
2876 Male, age 76, right hemisphere 33.7
2606 Female, age 67, right hemisphere 28.8
2418 Male, age 75, left hemisphere 26.1
Inferior temporal gyrus
nTPM: 29.4
1970 Female, age 85, right hemisphere 33.3
1880 Male, age 80, right hemisphere 29.8
1808 Male, age 76, left hemisphere 29.4
2689 Female, age 94, right hemisphere 29.4
1965 Female, age 91, left hemisphere 28.0
2430 Male, age 75, right hemisphere 26.7
Intraparietal deep sulcus
nTPM: 26.8
2607 Female, age 67, right hemisphere 31.6
2669 Male, age 75, left hemisphere 28.2
2102 Female, age 91, left hemisphere 26.7
2798 Male, age 76, left hemisphere 25.3
2230 Male, age 61, right hemisphere 25.2
2600 Female, age 94, right hemisphere 23.7
Lingual gyrus
nTPM: 33.7
2618 Female, age 94, left hemisphere 40.9
1893 Male, age 76, left hemisphere 34.0
2838 Male, age 80, right hemisphere 32.6
2073 Female, age 85, left hemisphere 32.4
2688 Male, age 75, right hemisphere 28.5
Middle cingulate cortex
nTPM: 29.2
2633 Male, age 74, left hemisphere 31.9
2028 Female, age 85, left hemisphere 30.5
2539 Male, age 75, left hemisphere 29.2
2640 Female, age 94, right hemisphere 28.9
2357 Female, age 67, right hemisphere 25.5
Middle temporal gyrus
nTPM: 28.9
2616 Female, age 94, left hemisphere 32.3
1799 Male, age 76, left hemisphere 29.8
2611 Male, age 75, right hemisphere 29.7
2034 Female, age 91, right hemisphere 27.2
1819 Male, age 80, right hemisphere 25.4
Occipital cortex
nTPM: 27.4
1842 Male, age 76, right hemisphere 36.5
2677 Female, age 67, right hemisphere 27.6
2608 Female, age 67, both hemispheres 25.5
2470 Male, age 75, right hemisphere 25.1
2426 Male, age 75, midline 22.4
Olfactory area
nTPM: 33.5
2352 Female, age 94, right hemisphere 48.7
1805 Female, age 85, right hemisphere 36.9
2542 Male, age 74, left hemisphere 30.4
2440 Male, age 75, left hemisphere 29.1
2222 Female, age 67, right hemisphere 28.0
2756 Female, age 67, right hemisphere 27.9
Olfactory tubercle
nTPM: 31.2
2487 Female, age 94, left hemisphere 34.5
2856 Male, age 75, right hemisphere 31.7
1846 Male, age 80, right hemisphere 30.0
1998 Female, age 91, both hemispheres 28.5
Orbitofrontal gyrus, anterior
nTPM: 35.5
2863 Female, age 85, right hemisphere 37.2
2862 Female, age 85, left hemisphere 37.0
2864 Female, age 67, left hemisphere 32.3
Paracentral lobule, anterior
nTPM: 23.8
2474 Male, age 74, left hemisphere 26.3
2638 Female, age 94, right hemisphere 25.5
1754 Male, age 75, left hemisphere 23.4
1776 Female, age 85, right hemisphere 23.3
2340 Female, age 67, right hemisphere 22.2
1926 Male, age 61, left hemisphere 22.0
Paracentral lobule, posterior
nTPM: 25.1
2446 Male, age 75, left hemisphere 27.7
2345 Male, age 61, left hemisphere 27.0
2551 Female, age 94, right hemisphere 24.7
1775 Female, age 85, right hemisphere 23.1
1764 Male, age 74, right hemisphere 22.9
Parietal operculum
nTPM: 29.8
2552 Female, age 94, right hemisphere 37.5
2719 Male, age 75, left hemisphere 29.4
1763 Male, age 74, left hemisphere 26.7
2356 Female, age 67, right hemisphere 25.5
Parieto-insular cortex
nTPM: 29.3
2508 Female, age 94, right hemisphere 37.5
2671 Male, age 75, left hemisphere 29.9
2232 Male, age 61, right hemisphere 29.1
2831 Male, age 76, right hemisphere 26.4
1976 Female, age 91, right hemisphere 23.4
Parieto-occipital transitional area
nTPM: 29.2
2683 Female, age 67, left hemisphere 33.0
2270 Male, age 61, right hemisphere 30.9
2674 Female, age 94, right hemisphere 29.5
2468 Male, age 75, left hemisphere 27.6
1784 Male, age 76, right hemisphere 24.8
Piriform cortex
nTPM: 28.8
2153 Female, age 85, left hemisphere 32.9
2347 Male, age 75, right hemisphere 24.8
Postcentral gyrus
nTPM: 21.0
2533 Male, age 75, right hemisphere 21.0
Postcentral gyrus, dorsal
nTPM: 24.6
2350 Male, age 75, left hemisphere 28.0
2544 Male, age 74, left hemisphere 27.1
2339 Female, age 67, right hemisphere 26.4
2151 Male, age 61, left hemisphere 23.1
1836 Female, age 85, right hemisphere 22.4
2477 Female, age 94, right hemisphere 20.8
Postcentral gyrus, middle
nTPM: 23.7
2545 Male, age 74, left hemisphere 25.3
2444 Male, age 75, left hemisphere 24.2
1897 Female, age 85, right hemisphere 24.0
2146 Female, age 67, right hemisphere 22.6
2248 Male, age 61, left hemisphere 22.2
Postcentral gyrus, ventral
nTPM: 25.2
2024 Female, age 85, right hemisphere 27.6
2836 Female, age 94, right hemisphere 25.2
2445 Male, age 75, left hemisphere 22.9
Posterior cingulate cortex
nTPM: 34.5
1759 Male, age 74, right hemisphere 38.8
2553 Female, age 94, right hemisphere 37.7
2473 Male, age 75, left hemisphere 27.1
Posterior cingulate cortex, dorsal
nTPM: 30.5
2540 Male, age 75, right hemisphere 35.1
2556 Female, age 67, right hemisphere 35.0
2634 Male, age 74, left hemisphere 31.0
2343 Male, age 61, left hemisphere 29.6
2076 Female, age 85, right hemisphere 28.1
2641 Female, age 94, right hemisphere 24.4
Posterior cingulate cortex, ventral
nTPM: 28.9
2346 Male, age 61, left hemisphere 30.1
2541 Male, age 75, right hemisphere 29.9
2635 Male, age 74, left hemisphere 29.8
1762 Female, age 94, right hemisphere 28.8
2448 Female, age 67, right hemisphere 28.3
1994 Female, age 85, right hemisphere 26.7
Posterior insular cortex
nTPM: 29.9
2603 Female, age 94, left hemisphere 35.2
2231 Male, age 61, left hemisphere 31.2
2597 Male, age 75, left hemisphere 30.2
2832 Female, age 91, right hemisphere 28.4
1823 Male, age 76, right hemisphere 27.8
2511 Female, age 67, right hemisphere 26.5
Precentral gyrus
nTPM: 27.1
2557 Male, age 75, right hemisphere 27.1
Precentral gyrus, dorsal
nTPM: 22.7
2354 Female, age 67, right hemisphere 25.0
2442 Male, age 75, left hemisphere 24.3
1756 Male, age 74, left hemisphere 22.0
2476 Female, age 94, right hemisphere 19.4
Precentral gyrus, middle
nTPM: 23.5
2549 Female, age 94, right hemisphere 32.7
2443 Male, age 75, left hemisphere 23.7
2475 Male, age 74, right hemisphere 22.8
1909 Male, age 61, left hemisphere 20.1
1969 Female, age 67, right hemisphere 18.4
Precentral gyrus, ventral
nTPM: 26.8
2550 Female, age 94, right hemisphere 35.9
2630 Male, age 75, left hemisphere 26.5
2678 Male, age 74, left hemisphere 23.2
2662 Female, age 67, right hemisphere 21.7
Precuneus
nTPM: 28.8
2594 Male, age 61, left hemisphere 33.9
1780 Female, age 91, right hemisphere 30.0
2510 Female, age 67, right hemisphere 29.4
2673 Female, age 94, right hemisphere 27.0
2467 Male, age 75, right hemisphere 26.4
1782 Male, age 76, right hemisphere 26.2
Premotor cortex, dorsal
nTPM: 26.7
2554 Female, age 67, right hemisphere 31.4
2536 Male, age 75, left hemisphere 29.1
2631 Male, age 74, left hemisphere 27.1
1878 Female, age 85, right hemisphere 23.5
2027 Male, age 61, left hemisphere 22.2
Premotor cortex, ventral
nTPM: 24.9
2637 Female, age 94, right hemisphere 27.9
1779 Male, age 61, left hemisphere 26.6
2349 Male, age 75, left hemisphere 26.3
1757 Male, age 74, left hemisphere 25.6
1881 Female, age 85, right hemisphere 22.3
1777 Female, age 67, left hemisphere 21.0
Retrosplenial cortex
nTPM: 40.8
1914 Male, age 76, right hemisphere 44.3
1951 Male, age 61, right hemisphere 44.1
2675 Female, age 94, left hemisphere 33.9
Subcentral gyrus, S2
nTPM: 27.5
2839 Female, age 94, right hemisphere 30.6
2555 Female, age 67, right hemisphere 29.0
1964 Female, age 85, right hemisphere 28.8
2072 Male, age 61, left hemisphere 26.1
2351 Male, age 75, left hemisphere 25.7
2762 Male, age 74, left hemisphere 24.8
Superior parietal lobule
nTPM: 25.5
2605 Female, age 67, right hemisphere 30.5
2672 Female, age 94, right hemisphere 27.8
2229 Male, age 61, right hemisphere 26.9
1800 Male, age 76, right hemisphere 22.2
1992 Female, age 91, right hemisphere 20.3
Superior temporal gyrus
nTPM: 29.8
2025 Male, age 80, right hemisphere 31.2
2615 Female, age 94, left hemisphere 30.7
1843 Male, age 76, left hemisphere 30.4
2687 Male, age 75, right hemisphere 28.4
1844 Female, age 91, left hemisphere 28.0
Supplementary motor cortex
nTPM: 26.1
2548 Female, age 94, right hemisphere 29.6
2537 Male, age 75, left hemisphere 27.1
2632 Male, age 74, left hemisphere 26.1
1993 Male, age 61, left hemisphere 21.7
Supramarginal gyrus
nTPM: 30.3
2601 Female, age 94, left hemisphere 34.7
2415 Male, age 61, left hemisphere 29.9
2513 Female, age 72, left hemisphere 29.8
1798 Male, age 76, right hemisphere 29.0
1991 Female, age 91, right hemisphere 28.0
Temporal pole
nTPM: 33.8
2612 Female, age 94, left hemisphere 44.9
1832 Female, age 91, left hemisphere 36.5
2518 Male, age 75, right hemisphere 29.5
1826 Male, age 76, right hemisphere 29.2
1853 Female, age 85, right hemisphere 28.8
Temporo-insular cortex, parainsular gyrus
nTPM: 34.8
2676 Female, age 94, right hemisphere 51.3
1802 Male, age 76, left hemisphere 36.0
2264 Female, age 91, right hemisphere 32.1
2512 Female, age 67, right hemisphere 31.5
2598 Male, age 75, left hemisphere 29.8
2416 Male, age 61, right hemisphere 28.4
Temporo-occipital transitional zone
nTPM: 32.0
1900 Male, age 76, left hemisphere 35.2
2251 Female, age 85, right hemisphere 32.2
1793 Male, age 80, right hemisphere 28.5
Transversal temporal gyrus, anterior
nTPM: 26.4
1888 Female, age 91, left hemisphere 29.2
2610 Male, age 75, right hemisphere 27.8
1809 Male, age 76, right hemisphere 26.3
2522 Female, age 94, left hemisphere 24.9
1910 Male, age 80, right hemisphere 23.8
Transversal temporal gyrus, posterior
nTPM: 27.9
2614 Female, age 94, left hemisphere 31.5
1967 Female, age 91, right hemisphere 29.1
1922 Male, age 76, left hemisphere 27.8
2520 Male, age 75, right hemisphere 26.7
2833 Male, age 80, right hemisphere 24.6

CEREBRAL CORTEX - HPA PFC Brain RNA-seq
Max subtype nTPMi 17.7
Sample id Sample description nTPM
Anterior cingulate gyrus, pregenual-dorsal
nTPM: 15.7
1517 Female, age 67, left hemisphere 19.4
1518 Female, age 67, right hemisphere 17.6
1513 Male, age 74, left hemisphere 16.9
1514 Male, age 74, right hemisphere 16.3
1510 Male, age 61, left hemisphere 14.9
1511 Male, age 61, right hemisphere 14.7
1512 Male, age 75, left hemisphere 14.5
1516 Female, age 85, left hemisphere 14.0
1515 Female, age 94, right hemisphere 13.0
Anterior cingulate gyrus, pregenual-ventral
nTPM: 16.5
1521 Male, age 74, left hemisphere 22.1
1519 Male, age 61, left hemisphere 18.9
1523 Female, age 67, left hemisphere 14.1
1522 Male, age 74, right hemisphere 13.9
1520 Male, age 75, right hemisphere 13.2
Anterior cingulate gyrus, subgenual
nTPM: 17.7
1527 Male, age 74, left hemisphere 27.2
1528 Male, age 74, right hemisphere 21.6
1525 Male, age 75, left hemisphere 17.8
1526 Male, age 75, right hemisphere 17.2
1524 Male, age 61, left hemisphere 15.5
1530 Female, age 67, right hemisphere 12.6
1529 Female, age 85, left hemisphere 11.9
Dorsolateral prefrontal cortex
nTPM: 8.4
1450 Female, age 67, right hemisphere 11.7
1446 Male, age 74, right hemisphere 9.2
1448 Female, age 94, right hemisphere 8.9
1444 Male, age 75, left hemisphere 8.3
1445 Male, age 75, right hemisphere 7.2
1447 Female, age 94, left hemisphere 7.0
1449 Female, age 85, right hemisphere 6.9
Dorsomedial prefrontal cortex
nTPM: 9.8
1442 Male, age 75, right hemisphere 12.1
1443 Female, age 67, right hemisphere 11.6
1439 Male, age 61, left hemisphere 8.9
1441 Male, age 75, left hemisphere 8.6
1440 Male, age 61, right hemisphere 7.8
Frontal cortex
nTPM: 7.9
1582 Female, age 67, left hemisphere 10.1
1573 Male, age 61, right hemisphere 9.4
1574 Male, age 75, left hemisphere 9.1
1575 Male, age 75, right hemisphere 8.8
1577 Male, age 74, right hemisphere 8.8
1583 Female, age 67, right hemisphere 7.6
1576 Male, age 74, left hemisphere 7.3
1578 Female, age 94, left hemisphere 7.1
1580 Female, age 85, left hemisphere 7.0
1572 Male, age 61, left hemisphere 6.5
1579 Female, age 94, right hemisphere 6.4
1581 Female, age 85, right hemisphere 6.1
Frontomarginal cortex
nTPM: 8.1
1472 Female, age 67, left hemisphere 11.3
1468 Male, age 74, left hemisphere 9.9
1470 Female, age 94, right hemisphere 8.7
1469 Female, age 94, left hemisphere 8.5
1466 Male, age 61, right hemisphere 8.1
1465 Male, age 61, left hemisphere 7.9
1473 Female, age 67, right hemisphere 7.6
1467 Male, age 75, right hemisphere 6.2
1471 Female, age 85, left hemisphere 4.8
Frontopolar cortex
nTPM: 8.7
1463 Female, age 67, left hemisphere 14.2
1462 Female, age 94, left hemisphere 10.8
1464 Female, age 67, right hemisphere 9.4
1461 Male, age 75, right hemisphere 7.1
1459 Male, age 61, right hemisphere 6.6
1460 Male, age 75, left hemisphere 6.4
1458 Male, age 61, left hemisphere 6.2
Gyrus rectus
nTPM: 8.1
1478 Female, age 94, left hemisphere 14.1
1479 Female, age 94, right hemisphere 8.3
1477 Male, age 75, right hemisphere 7.9
1474 Male, age 61, left hemisphere 7.6
1481 Female, age 67, left hemisphere 7.0
1476 Male, age 75, left hemisphere 6.9
1480 Female, age 85, left hemisphere 6.8
1475 Male, age 61, right hemisphere 6.3
Inferior frontal gyrus, orbital
nTPM: 14.5
1504 Male, age 74, left hemisphere 18.1
1502 Male, age 75, left hemisphere 17.6
1509 Female, age 67, right hemisphere 16.6
1503 Male, age 75, right hemisphere 16.5
1505 Male, age 74, right hemisphere 15.2
1506 Female, age 94, left hemisphere 14.0
1500 Male, age 61, left hemisphere 13.1
1507 Female, age 85, left hemisphere 11.7
1508 Female, age 85, right hemisphere 11.3
1501 Male, age 61, right hemisphere 10.7
Inferior frontal gyrus, triangular
nTPM: 13.8
1545 Male, age 74, right hemisphere 21.8
1544 Male, age 75, right hemisphere 15.9
1543 Male, age 61, right hemisphere 15.6
1546 Female, age 94, right hemisphere 15.0
1542 Male, age 61, left hemisphere 12.3
1547 Female, age 85, left hemisphere 11.5
1549 Female, age 67, left hemisphere 10.8
1548 Female, age 85, right hemisphere 7.4
Orbitofrontal gyrus, lateral
nTPM: 14.0
1497 Female, age 85, left hemisphere 17.0
1499 Female, age 67, right hemisphere 16.1
1495 Female, age 94, left hemisphere 15.5
1496 Female, age 94, right hemisphere 15.3
1494 Male, age 75, left hemisphere 14.5
1493 Male, age 61, right hemisphere 11.2
1498 Female, age 85, right hemisphere 8.2
Orbitofrontal gyrus, medial
nTPM: 7.1
1491 Female, age 67, left hemisphere 9.9
1492 Female, age 67, right hemisphere 9.5
1489 Female, age 85, left hemisphere 7.9
1488 Female, age 94, right hemisphere 7.7
1486 Male, age 74, right hemisphere 7.6
1483 Male, age 75, left hemisphere 6.9
1482 Male, age 61, left hemisphere 6.7
1487 Female, age 94, left hemisphere 6.5
1490 Female, age 85, right hemisphere 6.0
1484 Male, age 75, right hemisphere 4.8
1485 Male, age 74, left hemisphere 4.6
Orbitofrontal gyrus, posterior
nTPM: 16.3
1536 Female, age 94, left hemisphere 22.8
1535 Male, age 74, left hemisphere 22.2
1540 Female, age 67, left hemisphere 22.0
1541 Female, age 67, right hemisphere 20.0
1537 Female, age 94, right hemisphere 18.8
1534 Male, age 75, right hemisphere 14.2
1533 Male, age 75, left hemisphere 13.4
1538 Female, age 85, left hemisphere 12.2
1539 Female, age 85, right hemisphere 11.8
1532 Male, age 61, right hemisphere 11.1
1531 Male, age 61, left hemisphere 10.3
Subcallosal gyrus
nTPM: 9.6
1560 Female, age 67, left hemisphere 13.8
1555 Male, age 74, right hemisphere 12.2
1554 Male, age 74, left hemisphere 11.6
1550 Male, age 61, left hemisphere 11.4
1551 Male, age 61, right hemisphere 10.7
1556 Female, age 94, left hemisphere 9.7
1557 Female, age 94, right hemisphere 9.7
1552 Male, age 75, left hemisphere 8.4
1558 Female, age 85, left hemisphere 8.3
1553 Male, age 75, right hemisphere 6.6
1559 Female, age 85, right hemisphere 6.2
1561 Female, age 67, right hemisphere 6.2
Superior frontal gyrus
nTPM: 8.3
1571 Female, age 67, right hemisphere 13.1
1564 Male, age 75, left hemisphere 10.0
1565 Male, age 75, right hemisphere 9.6
1566 Male, age 74, right hemisphere 9.4
1562 Male, age 61, left hemisphere 8.3
1563 Male, age 61, right hemisphere 8.1
1567 Female, age 94, left hemisphere 7.8
1568 Female, age 94, right hemisphere 6.3
1570 Female, age 85, right hemisphere 5.3
1569 Female, age 85, left hemisphere 5.0
Temporal cortex
nTPM: 9.7
1595 Female, age 94, right hemisphere 13.5
1593 Male, age 74, right hemisphere 12.7
1592 Male, age 74, left hemisphere 10.4
1594 Female, age 94, left hemisphere 10.4
1591 Male, age 75, right hemisphere 9.3
1590 Male, age 61, right hemisphere 5.9
1596 Female, age 85, right hemisphere 5.6
Ventrolateral prefrontal cortex
nTPM: 9.3
1456 Female, age 67, left hemisphere 13.0
1457 Female, age 67, right hemisphere 10.0
1452 Male, age 74, left hemisphere 9.9
1454 Female, age 94, left hemisphere 9.7
1453 Male, age 74, right hemisphere 8.3
1451 Male, age 75, right hemisphere 7.9
1455 Female, age 85, right hemisphere 6.1
Ventromedial prefrontal cortex
nTPM: 8.7
1435 Female, age 94, right hemisphere 13.0
1438 Female, age 67, left hemisphere 9.8
1432 Male, age 61, left hemisphere 9.3
1433 Male, age 61, right hemisphere 8.7
1434 Male, age 75, right hemisphere 8.2
1437 Female, age 85, right hemisphere 6.1
1436 Female, age 85, left hemisphere 5.7

CEREBRAL CORTEX - GTEx RNA-seqi
Max subtype nTPMi 20.5
GTEx sample id Sample description nTPM
16.018.923.111.032.605101520253035404550
Brain - Anterior cingulate cortex (BA24)
Average nTPM: 20.5
Samples: 233

Max nTPM: 54.0
Min nTPM: 11.0
Std nTPM: 6.6
Median nTPM: 18.9
GTEX-14E6C-0011-R3a-SM-G8W87 40-49 years, male 54.0
GTEX-13QJC-0011-R3a-SM-H65ZQ 60-69 years, female 50.8
GTEX-1B996-0011-R3b-SM-9QEGY 60-69 years, male 48.4
GTEX-13OW5-0011-R3a-SM-5L3I5 60-69 years, male 38.4
GTEX-1GN73-0011-R3b-SM-9QEIL 60-69 years, male 38.0
GTEX-14BMV-0011-R3a-SM-5ZZU7 50-59 years, male 37.9
GTEX-11WQK-0011-R3b-SM-DO93K 50-59 years, male 36.4
GTEX-13N1W-0011-R3a-SM-5MR5E 70-79 years, male 36.1
GTEX-13O3O-0011-R3b-SM-5KM3R 60-69 years, female 34.4
GTEX-14753-0011-R3b-SM-GI4X3 60-69 years, male 34.4
GTEX-145LU-0011-R3a-SM-5P9K2 50-59 years, male 32.6
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17.219.621.710.927.9051015202530354045
Brain - Cortex
Average nTPM: 20.1
Samples: 270

Max nTPM: 46.4
Min nTPM: 10.2
Std nTPM: 4.3
Median nTPM: 19.6
GTEX-1GN73-3126-SM-9KNTY 60-69 years, male 46.4
GTEX-1JMQL-2826-SM-ARU91 50-59 years, female 38.6
GTEX-1JJE9-2926-SM-CY8HV 70-79 years, male 36.1
GTEX-11OC5-0726-SM-5P9JK 60-69 years, male 35.7
GTEX-1MA7X-2526-SM-GPI9W 60-69 years, male 33.1
GTEX-1CAV2-2726-SM-7IGNN 40-49 years, female 31.0
GTEX-11WQK-3026-SM-5EQL6 50-59 years, male 30.1
GTEX-13N1W-3026-SM-GIN9V 70-79 years, male 29.9
GTEX-OHPN-2526-SM-2I5H3 60-69 years, female 29.7
GTEX-1HCU6-3126-SM-CL54L 60-69 years, female 29.4
GTEX-1C6VQ-3026-SM-7IGPU 50-59 years, male 29.1
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13.415.719.49.828.3051015202530354045505560
Brain - Frontal Cortex (BA9)
Average nTPM: 17.1
Samples: 269

Max nTPM: 63.1
Min nTPM: 9.8
Std nTPM: 5.4
Median nTPM: 15.7
GTEX-1B996-0011-R10b-SM-CJI3T 60-69 years, male 63.1
GTEX-13QJC-0011-R10a-SM-5SI63 60-69 years, female 39.0
GTEX-1GN73-0011-R10b-SM-CKZNR 60-69 years, male 34.2
GTEX-13N2G-0011-R10a-SM-5MR34 60-69 years, male 29.7
GTEX-1JMQL-0011-R10b-SM-F341C 50-59 years, female 29.4
GTEX-16XZZ-0011-R10b-SM-7LT91 60-69 years, male 29.2
GTEX-1LSVX-0011-R10a-SM-F3K5E 60-69 years, male 28.5
GTEX-1R46S-0011-R10a-SM-F3416 60-69 years, female 28.3
GTEX-13PLJ-0011-R10a-SM-GJ3QE 60-69 years, female 27.6
GTEX-ZV68-0011-R10a-SM-51MT7 50-59 years, female 27.5
GTEX-13O3O-0011-R10a-SM-5LUA9 60-69 years, female 27.2
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CEREBRAL CORTEX - FANTOM5 CAGEi
Max subtype Scaled Tags Per Millioni 49.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Occipital cortex
Scaled Tags Per Million: 39.5
FF:10163-103B1 76 years, female 39.5
Postcentral gyrus
Scaled Tags Per Million: 39.2
FF:10032-101E5 44-52 years, mixed 39.2
Frontal lobe
Scaled Tags Per Million: 38.7
FF:10040-101F4 32-61 years, mixed 38.7
Insula
Scaled Tags Per Million: 49.2
FF:10039-101F3 20-68 years, mixed 49.2
Medial frontal gyrus
Scaled Tags Per Million: 36.2
FF:10150-102I6 76 years, female 36.2
Medial temporal gyrus
Scaled Tags Per Million: 34.9
FF:10156-103A3 76 years, female 37.8
FF:10183-103D3 60 years, female 31.9
Occipital lobe
Scaled Tags Per Million: 30.4
FF:10076-102A4 27 years, male 30.4
Occipital pole
Scaled Tags Per Million: 41.9
FF:10036-101E9 22-68 years, mixed 41.9
Paracentral gyrus
Scaled Tags Per Million: 36.4
FF:10035-101E8 22-69 years, mixed 36.4
Parietal lobe
Scaled Tags Per Million: 32.4
FF:10034-101E7 35-89 years, mixed 37.1
FF:10171-103B9 60 years, female 30.9
FF:10157-103A4 76 years, female 29.3
Temporal lobe
Scaled Tags Per Million: 49.8
FF:10031-101E4 32-61 years, mixed 49.8

CEREBRAL CORTEX - Pig RNA-seqi
Max subtype nTPMi 17.6
Pig sample Sample description nTPM
13.115.919.112.920.202468101214161820
 		Occipital cortex
nTPM: 16.3
Samples: 4

Max nTPM: 20.2
Min nTPM: 12.9
Sample A Female 18.7
Sample B Female 13.2
Sample C Male 20.2
Sample D Male 12.9
12.914.616.912.119.8024681012141618
 		Retrosplenial cortex
nTPM: 15.3
Samples: 4

Max nTPM: 19.8
Min nTPM: 12.1
Sample A Female 13.2
Sample B Female 12.1
Sample C Male 19.8
Sample D Male 16.0
Cingulate cortex
nTPM: 15.3
Samples: 4

Max nTPM: 17.7
Min nTPM: 13.0
Sample A Female 17.2
Sample B Female 13.0
Sample C Male 17.7
Sample D Male 13.2
Insular cortex
nTPM: 15.5
Samples: 4

Max nTPM: 17.2
Min nTPM: 12.8
Sample A Female 17.2
Sample B Female 12.8
Sample C Male 15.3
Sample D Male 16.7
14.415.316.513.418.0024681012141618
 		Motor cortex
nTPM: 15.5
Samples: 4

Max nTPM: 18.0
Min nTPM: 13.4
Sample A Female 18.0
Sample B Female 14.7
Sample C Male 16.0
Sample D Male 13.4
16.516.617.816.116.702468101214161820
 		Prefrontal cortex
nTPM: 17.6
Samples: 4

Max nTPM: 20.9
Min nTPM: 16.1
Sample A Female 20.9
Sample B Female 16.7
Sample C Male 16.1
Sample D Male 16.6
Somatosensory cortex
nTPM: 15.8
Samples: 3

Max nTPM: 16.6
Min nTPM: 14.7
Sample B Female 14.7
Sample C Male 16.1
Sample D Male 16.6
14.316.318.113.318.3024681012141618
 		Temporal cortex
nTPM: 16.1
Samples: 4

Max nTPM: 18.3
Min nTPM: 13.3
Sample A Female 14.6
Sample B Female 18.0
Sample C Male 18.3
Sample D Male 13.3

CEREBRAL CORTEX - Mouse RNA-seqi
Max subtype nTPMi 21.5
Mouse sample Sample description nTPM
19.120.621.120.622.20246810121416182022
 		Occipital cortex
nTPM: 19.6
Samples: 4

Max nTPM: 22.2
Min nTPM: 14.7
Sample A Male 20.7
Sample B Male 14.7
Sample C Female 20.6
Sample D Female 22.2
20.722.423.222.325.7024681012141618202224
 		Frontal cortex
nTPM: 21.6
Samples: 4

Max nTPM: 25.7
Min nTPM: 15.8
Sample A Male 15.8
Sample B Male 25.7
Sample C Female 22.3
Sample D Female 22.4
17.318.620.516.822.40246810121416182022
 		Retrosplenial and cingulate cortex
nTPM: 19.1
Samples: 4

Max nTPM: 22.4
Min nTPM: 16.8
Sample A Male 19.9
Sample B Male 22.4
Sample C Female 16.8
Sample D Female 17.4
17.719.621.216.821.402468101214161820
 		Somatosensory cortex
nTPM: 19.3
Samples: 4

Max nTPM: 21.4
Min nTPM: 16.8
Sample A Male 16.8
Sample B Male 21.1
Sample C Female 21.4
Sample D Female 18.0

CEREBRAL CORTEX - Allen Mouse ISHi
Max subtype Expression energyi 16.7
Allen experiment id Experiment description Expression energy
Cerebral cortex
Expression energy: 16.7
68637682 Antisense, RP_050126_01_D05, Mouse strain C57BL/6J (56 days, male) 16.7

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