CEREBRAL CORTEX - Expression summary
Protein expression
Cerebral cortexi
h
m
l
n
Endothelial cells: Low
Glial cells: Medium
Neuronal cells: High
Neuropil: Medium
RNA expressioni
Consensus:6.6 nTPM
HPA:6.6 nTPM
HPA Brain:5.7 nTPM
HPA PFC Brain:3.2 nTPM
GTEx:5.3 nTPM
FANTOM5:42.2 Scaled Tags Per Million
Mouse:11.4 nTPM
Allen mouse:0.4 Expression energy
BRAIN - SINGLE CELL RNA EXPRESSION
Brain excitatory neuronsBrain inhibitory neuronsOther brain neuronsAstrocytesBergmann gliaOligodendrocyte progenitor cellsOligodendrocytesMicrogliaEpendymal cellsChoroid plexus epithelial cellsVascular endothelial cellsPericytesVascular smooth muscle cellsFibroblastsMonocytesMacrophagesT-cellsB-cellsNK-cells050100150200nCPM

CEREBRAL CORTEX - Antibody stainingi
Antibody HPA004691
Endothelial cells Low
Glial cells Medium
Neuronal cells High
Neuropil Medium



CEREBRAL CORTEX - HPA RNA-seqi
Average nTPMi 6.6
N/A
Male, age 5
Cerebral cortex sample 48
nTPM: 8.1
overview
Female, age 40
Cerebral cortex sample 105
nTPM: 4.9
Cell types%
Neuronal cells:
35

Glial cells and endothelial cells:
65
overview
Male, age 70
Cerebral cortex sample 106
nTPM: 6.9
Cell types%
Neuronal cells:
35

Glial cells and endothelial cells:
65

CEREBRAL CORTEX - HPA Brain RNA-seq
Max subtype nTPMi 5.7
Sample id Sample description nTPM
Angular gyrus
nTPM: 3.0
2221 Female, age 67, right hemisphere 3.5
1866 Male, age 76, both hemispheres 3.3
2265 Female, age 91, left hemisphere 3.3
2260 Female, age 72, left hemisphere 3.2
2602 Female, age 94, right hemisphere 3.1
2103 Male, age 75, left hemisphere 2.7
1790 Male, age 76, right hemisphere 2.6
2722 Male, age 61, left hemisphere 2.6
Anterior cingulate cortex, supragenual-dorsal
nTPM: 2.6
2472 Male, age 75, left hemisphere 3.2
1896 Female, age 85, right hemisphere 3.1
2342 Female, age 94, right hemisphere 2.5
2547 Male, age 74, left hemisphere 2.4
2478 Female, age 67, right hemisphere 1.8
Anterior cingulate cortex, supragenual-ventral
nTPM: 2.8
2479 Female, age 67, right hemisphere 3.1
1950 Female, age 85, right hemisphere 3.0
2538 Male, age 75, left hemisphere 2.8
1761 Male, age 74, left hemisphere 2.6
1755 Female, age 94, right hemisphere 2.2
Anterior insular cortex, dorsal
nTPM: 3.2
2001 Male, age 76, right hemisphere 4.0
2506 Female, age 94, right hemisphere 3.3
2670 Male, age 75, left hemisphere 3.1
2235 Female, age 91, right hemisphere 2.5
Anterior insular cortex, ventral
nTPM: 3.5
2596 Male, age 75, left hemisphere 4.3
1925 Female, age 91, left hemisphere 3.6
1852 Male, age 76, left hemisphere 3.5
2507 Female, age 94, left hemisphere 3.5
2262 Female, age 67, right hemisphere 3.3
2757 Male, age 61, right hemisphere 3.0
Area parastriata, inferior
nTPM: 3.1
1758 Female, age 72, right hemisphere 3.7
1760 Female, age 67, left hemisphere 3.5
2509 Female, age 94, left hemisphere 3.2
2234 Male, age 75, left hemisphere 3.0
2421 Female, age 91, left hemisphere 3.0
2268 Male, age 61, right hemisphere 2.9
1789 Male, age 76, right hemisphere 2.7
Area parastriata, parietal
nTPM: 3.0
2233 Male, age 61, right hemisphere 3.2
2680 Female, age 94, right hemisphere 3.2
1785 Male, age 76, right hemisphere 2.9
2236 Female, age 91, left hemisphere 2.9
2420 Male, age 75, left hemisphere 2.8
Area parastriata, superior
nTPM: 3.0
1773 Female, age 91, left hemisphere 3.6
2419 Male, age 75, right hemisphere 3.6
2684 Female, age 67, left hemisphere 3.0
2604 Female, age 94, right hemisphere 2.8
2881 Male, age 76, left hemisphere 2.8
2435 Male, age 61, left hemisphere 2.2
Area parastriata, temporal
nTPM: 3.1
2681 Female, age 94, right hemisphere 3.4
2471 Male, age 75, left hemisphere 3.2
2267 Male, age 61, right hemisphere 3.1
2424 Female, age 67, left hemisphere 3.0
1804 Male, age 76, right hemisphere 2.9
Area striata
nTPM: 2.9
2427 Female, age 91, left hemisphere 3.4
1753 Female, age 72, right hemisphere 3.2
2417 Male, age 61, right hemisphere 3.0
2679 Female, age 94, right hemisphere 2.8
1884 Male, age 76, left hemisphere 2.7
2002 Female, age 91, right hemisphere 2.6
Claustrum
nTPM: 3.2
2392 Female, age 94, both hemispheres 3.6
2568 Male, age 61, both hemispheres 3.6
2198 Male, age 80, both hemispheres 3.4
2196 Female, age 79, unknown 3.3
1956 Male, age 74, unknown 3.2
2284 Female, age 91, both hemispheres 3.2
2491 Male, age 75, both hemispheres 3.0
2645 Female, age 72, unknown 3.0
2292 Female, age 85, both hemispheres 2.7
Frontal eye field
nTPM: 3.3
2761 Female, age 94, left hemisphere 3.8
2441 Male, age 75, left hemisphere 3.7
2543 Male, age 74, left hemisphere 2.9
2147 Male, age 61, left hemisphere 2.8
Frontal operculum
nTPM: 3.4
2030 Male, age 61, right hemisphere 3.7
2348 Male, age 75, left hemisphere 3.3
2781 Female, age 85, right hemisphere 3.2
Fusiform gyrus
nTPM: 3.3
2433 Female, age 72, left hemisphere 4.6
2431 Male, age 75, right hemisphere 3.9
1807 Male, age 76, left hemisphere 3.4
2617 Female, age 94, left hemisphere 3.3
2784 Female, age 85, left hemisphere 3.0
2112 Male, age 80, both hemispheres 2.9
2074 Female, age 91, left hemisphere 2.3
Inferior frontal gyrus, opercular
nTPM: 2.8
2872 Female, age 94, right hemisphere 3.3
2871 Female, age 94, left hemisphere 3.2
2865 Male, age 61, left hemisphere 3.0
2868 Male, age 75, right hemisphere 3.0
2867 Male, age 75, left hemisphere 2.9
2869 Male, age 74, left hemisphere 2.8
2875 Female, age 67, left hemisphere 2.8
2873 Female, age 85, left hemisphere 2.7
2874 Female, age 85, right hemisphere 2.4
2866 Male, age 61, right hemisphere 2.2
Inferior parietal lobule
nTPM: 3.3
2418 Male, age 75, left hemisphere 4.4
2876 Male, age 76, right hemisphere 3.3
2599 Female, age 94, left hemisphere 2.9
2606 Female, age 67, right hemisphere 2.5
Inferior temporal gyrus
nTPM: 3.1
1880 Male, age 80, right hemisphere 3.7
1808 Male, age 76, left hemisphere 3.3
1970 Female, age 85, right hemisphere 3.3
2689 Female, age 94, right hemisphere 3.1
2430 Male, age 75, right hemisphere 3.0
1965 Female, age 91, left hemisphere 2.5
Intraparietal deep sulcus
nTPM: 3.0
2798 Male, age 76, left hemisphere 3.7
2607 Female, age 67, right hemisphere 3.3
2600 Female, age 94, right hemisphere 3.0
2102 Female, age 91, left hemisphere 2.8
2669 Male, age 75, left hemisphere 2.7
2230 Male, age 61, right hemisphere 2.6
Lingual gyrus
nTPM: 3.3
2838 Male, age 80, right hemisphere 3.8
2618 Female, age 94, left hemisphere 3.4
2073 Female, age 85, left hemisphere 3.3
1893 Male, age 76, left hemisphere 3.2
2688 Male, age 75, right hemisphere 3.0
Middle cingulate cortex
nTPM: 3.0
2357 Female, age 67, right hemisphere 3.6
2028 Female, age 85, left hemisphere 3.4
2539 Male, age 75, left hemisphere 3.2
2640 Female, age 94, right hemisphere 2.9
2633 Male, age 74, left hemisphere 1.9
Middle temporal gyrus
nTPM: 3.3
1819 Male, age 80, right hemisphere 3.5
2034 Female, age 91, right hemisphere 3.5
2616 Female, age 94, left hemisphere 3.3
2611 Male, age 75, right hemisphere 3.0
1799 Male, age 76, left hemisphere 2.9
Occipital cortex
nTPM: 3.3
2426 Male, age 75, midline 3.7
2677 Female, age 67, right hemisphere 3.6
1842 Male, age 76, right hemisphere 3.3
2608 Female, age 67, both hemispheres 3.2
2470 Male, age 75, right hemisphere 2.9
Olfactory area
nTPM: 3.1
2352 Female, age 94, right hemisphere 3.8
2542 Male, age 74, left hemisphere 3.1
1805 Female, age 85, right hemisphere 3.0
2440 Male, age 75, left hemisphere 3.0
2756 Female, age 67, right hemisphere 3.0
2222 Female, age 67, right hemisphere 2.9
Olfactory tubercle
nTPM: 3.3
1846 Male, age 80, right hemisphere 3.7
1998 Female, age 91, both hemispheres 3.5
2487 Female, age 94, left hemisphere 3.3
2856 Male, age 75, right hemisphere 2.9
Orbitofrontal gyrus, anterior
nTPM: 5.7
2863 Female, age 85, right hemisphere 11.7
2862 Female, age 85, left hemisphere 2.7
2864 Female, age 67, left hemisphere 2.7
Paracentral lobule, anterior
nTPM: 3.0
1926 Male, age 61, left hemisphere 3.2
1754 Male, age 75, left hemisphere 3.1
2340 Female, age 67, right hemisphere 3.1
2638 Female, age 94, right hemisphere 3.1
1776 Female, age 85, right hemisphere 2.9
2474 Male, age 74, left hemisphere 2.7
Paracentral lobule, posterior
nTPM: 2.6
1764 Male, age 74, right hemisphere 3.2
2446 Male, age 75, left hemisphere 2.8
1775 Female, age 85, right hemisphere 2.7
2551 Female, age 94, right hemisphere 2.5
2345 Male, age 61, left hemisphere 2.0
Parietal operculum
nTPM: 3.3
2552 Female, age 94, right hemisphere 3.8
2356 Female, age 67, right hemisphere 3.6
1763 Male, age 74, left hemisphere 3.3
2719 Male, age 75, left hemisphere 2.5
Parieto-insular cortex
nTPM: 3.1
2831 Male, age 76, right hemisphere 3.6
2671 Male, age 75, left hemisphere 3.3
1976 Female, age 91, right hemisphere 3.1
2232 Male, age 61, right hemisphere 3.0
2508 Female, age 94, right hemisphere 2.7
Parieto-occipital transitional area
nTPM: 3.2
1784 Male, age 76, right hemisphere 3.2
2468 Male, age 75, left hemisphere 3.2
2683 Female, age 67, left hemisphere 3.2
2270 Male, age 61, right hemisphere 3.1
2674 Female, age 94, right hemisphere 3.0
Piriform cortex
nTPM: 3.6
2347 Male, age 75, right hemisphere 3.7
2153 Female, age 85, left hemisphere 3.4
Postcentral gyrus
nTPM: 2.8
2533 Male, age 75, right hemisphere 2.8
Postcentral gyrus, dorsal
nTPM: 2.9
2339 Female, age 67, right hemisphere 3.5
2544 Male, age 74, left hemisphere 3.3
2151 Male, age 61, left hemisphere 3.0
1836 Female, age 85, right hemisphere 2.9
2350 Male, age 75, left hemisphere 2.5
2477 Female, age 94, right hemisphere 2.0
Postcentral gyrus, middle
nTPM: 3.0
2545 Male, age 74, left hemisphere 3.5
2146 Female, age 67, right hemisphere 3.3
1897 Female, age 85, right hemisphere 2.9
2444 Male, age 75, left hemisphere 2.7
2248 Male, age 61, left hemisphere 2.6
Postcentral gyrus, ventral
nTPM: 3.4
2836 Female, age 94, right hemisphere 3.8
2024 Female, age 85, right hemisphere 3.3
2445 Male, age 75, left hemisphere 3.2
Posterior cingulate cortex
nTPM: 3.5
2553 Female, age 94, right hemisphere 4.1
1759 Male, age 74, right hemisphere 3.3
2473 Male, age 75, left hemisphere 3.1
Posterior cingulate cortex, dorsal
nTPM: 2.9
2343 Male, age 61, left hemisphere 3.2
2076 Female, age 85, right hemisphere 3.1
2540 Male, age 75, right hemisphere 3.0
2634 Male, age 74, left hemisphere 3.0
2556 Female, age 67, right hemisphere 2.9
2641 Female, age 94, right hemisphere 2.4
Posterior cingulate cortex, ventral
nTPM: 3.2
2346 Male, age 61, left hemisphere 3.7
1762 Female, age 94, right hemisphere 3.4
2541 Male, age 75, right hemisphere 3.4
1994 Female, age 85, right hemisphere 3.1
2635 Male, age 74, left hemisphere 2.9
2448 Female, age 67, right hemisphere 2.7
Posterior insular cortex
nTPM: 3.1
1823 Male, age 76, right hemisphere 3.4
2231 Male, age 61, left hemisphere 3.2
2597 Male, age 75, left hemisphere 3.2
2832 Female, age 91, right hemisphere 3.1
2511 Female, age 67, right hemisphere 3.0
2603 Female, age 94, left hemisphere 2.9
Precentral gyrus
nTPM: 2.9
2557 Male, age 75, right hemisphere 2.9
Precentral gyrus, dorsal
nTPM: 3.3
2354 Female, age 67, right hemisphere 4.0
1756 Male, age 74, left hemisphere 3.4
2442 Male, age 75, left hemisphere 2.9
2476 Female, age 94, right hemisphere 2.9
Precentral gyrus, middle
nTPM: 2.9
1909 Male, age 61, left hemisphere 3.1
2443 Male, age 75, left hemisphere 3.0
2549 Female, age 94, right hemisphere 3.0
1969 Female, age 67, right hemisphere 2.8
2475 Male, age 74, right hemisphere 2.7
Precentral gyrus, ventral
nTPM: 3.1
2550 Female, age 94, right hemisphere 3.3
2630 Male, age 75, left hemisphere 3.2
2662 Female, age 67, right hemisphere 3.0
2678 Male, age 74, left hemisphere 3.0
Precuneus
nTPM: 2.9
2673 Female, age 94, right hemisphere 3.6
2510 Female, age 67, right hemisphere 3.2
1780 Female, age 91, right hemisphere 2.8
2467 Male, age 75, right hemisphere 2.8
2594 Male, age 61, left hemisphere 2.8
1782 Male, age 76, right hemisphere 2.4
Premotor cortex, dorsal
nTPM: 3.5
2027 Male, age 61, left hemisphere 3.8
2536 Male, age 75, left hemisphere 3.6
2554 Female, age 67, right hemisphere 3.6
1878 Female, age 85, right hemisphere 3.5
2631 Male, age 74, left hemisphere 2.8
Premotor cortex, ventral
nTPM: 3.4
2349 Male, age 75, left hemisphere 4.0
1779 Male, age 61, left hemisphere 3.7
1881 Female, age 85, right hemisphere 3.3
1777 Female, age 67, left hemisphere 3.2
2637 Female, age 94, right hemisphere 3.1
1757 Male, age 74, left hemisphere 3.0
Retrosplenial cortex
nTPM: 2.8
1914 Male, age 76, right hemisphere 3.1
2675 Female, age 94, left hemisphere 2.9
1951 Male, age 61, right hemisphere 2.6
Subcentral gyrus, S2
nTPM: 3.2
2555 Female, age 67, right hemisphere 3.8
2351 Male, age 75, left hemisphere 3.7
2839 Female, age 94, right hemisphere 3.2
1964 Female, age 85, right hemisphere 3.0
2072 Male, age 61, left hemisphere 2.8
2762 Male, age 74, left hemisphere 2.8
Superior parietal lobule
nTPM: 2.8
1992 Female, age 91, right hemisphere 3.1
2229 Male, age 61, right hemisphere 3.1
2605 Female, age 67, right hemisphere 2.9
2672 Female, age 94, right hemisphere 2.7
1800 Male, age 76, right hemisphere 2.3
Superior temporal gyrus
nTPM: 3.6
2615 Female, age 94, left hemisphere 4.6
1843 Male, age 76, left hemisphere 4.0
2025 Male, age 80, right hemisphere 3.3
2687 Male, age 75, right hemisphere 3.2
1844 Female, age 91, left hemisphere 2.7
Supplementary motor cortex
nTPM: 3.1
2632 Male, age 74, left hemisphere 3.4
2537 Male, age 75, left hemisphere 3.2
1993 Male, age 61, left hemisphere 3.0
2548 Female, age 94, right hemisphere 2.6
Supramarginal gyrus
nTPM: 3.2
2601 Female, age 94, left hemisphere 3.5
2415 Male, age 61, left hemisphere 3.4
2513 Female, age 72, left hemisphere 3.3
1991 Female, age 91, right hemisphere 3.2
1798 Male, age 76, right hemisphere 2.8
Temporal pole
nTPM: 3.4
2612 Female, age 94, left hemisphere 3.7
1826 Male, age 76, right hemisphere 3.6
1832 Female, age 91, left hemisphere 3.5
1853 Female, age 85, right hemisphere 3.2
2518 Male, age 75, right hemisphere 2.7
Temporo-insular cortex, parainsular gyrus
nTPM: 3.1
2416 Male, age 61, right hemisphere 3.3
2598 Male, age 75, left hemisphere 3.3
2512 Female, age 67, right hemisphere 3.2
1802 Male, age 76, left hemisphere 3.1
2676 Female, age 94, right hemisphere 3.0
2264 Female, age 91, right hemisphere 2.9
Temporo-occipital transitional zone
nTPM: 2.8
1900 Male, age 76, left hemisphere 3.1
2251 Female, age 85, right hemisphere 2.8
1793 Male, age 80, right hemisphere 2.5
Transversal temporal gyrus, anterior
nTPM: 3.3
1910 Male, age 80, right hemisphere 3.8
1888 Female, age 91, left hemisphere 3.6
2522 Female, age 94, left hemisphere 3.4
2610 Male, age 75, right hemisphere 2.9
1809 Male, age 76, right hemisphere 2.8
Transversal temporal gyrus, posterior
nTPM: 3.2
1922 Male, age 76, left hemisphere 3.5
2520 Male, age 75, right hemisphere 3.5
2614 Female, age 94, left hemisphere 3.3
2833 Male, age 80, right hemisphere 3.0
1967 Female, age 91, right hemisphere 2.9

CEREBRAL CORTEX - HPA PFC Brain RNA-seq
Max subtype nTPMi 3.2
Sample id Sample description nTPM
Anterior cingulate gyrus, pregenual-dorsal
nTPM: 1.5
1510 Male, age 61, left hemisphere 2.1
1512 Male, age 75, left hemisphere 2.1
1511 Male, age 61, right hemisphere 1.8
1516 Female, age 85, left hemisphere 1.7
1518 Female, age 67, right hemisphere 1.6
1517 Female, age 67, left hemisphere 1.5
1515 Female, age 94, right hemisphere 1.3
1514 Male, age 74, right hemisphere 1.0
1513 Male, age 74, left hemisphere 0.8
Anterior cingulate gyrus, pregenual-ventral
nTPM: 1.0
1519 Male, age 61, left hemisphere 1.6
1520 Male, age 75, right hemisphere 1.4
1523 Female, age 67, left hemisphere 1.0
1522 Male, age 74, right hemisphere 0.7
1521 Male, age 74, left hemisphere 0.4
Anterior cingulate gyrus, subgenual
nTPM: 1.6
1529 Female, age 85, left hemisphere 2.5
1524 Male, age 61, left hemisphere 1.9
1525 Male, age 75, left hemisphere 1.7
1526 Male, age 75, right hemisphere 1.6
1530 Female, age 67, right hemisphere 1.6
1527 Male, age 74, left hemisphere 0.9
1528 Male, age 74, right hemisphere 0.7
Dorsolateral prefrontal cortex
nTPM: 2.2
1445 Male, age 75, right hemisphere 3.7
1446 Male, age 74, right hemisphere 2.6
1444 Male, age 75, left hemisphere 2.4
1449 Female, age 85, right hemisphere 2.4
1447 Female, age 94, left hemisphere 2.0
1448 Female, age 94, right hemisphere 1.7
1450 Female, age 67, right hemisphere 1.0
Dorsomedial prefrontal cortex
nTPM: 2.6
1440 Male, age 61, right hemisphere 4.3
1439 Male, age 61, left hemisphere 3.7
1443 Female, age 67, right hemisphere 2.5
1441 Male, age 75, left hemisphere 2.3
1442 Male, age 75, right hemisphere 0.1
Frontal cortex
nTPM: 1.8
1572 Male, age 61, left hemisphere 3.3
1576 Male, age 74, left hemisphere 2.6
1580 Female, age 85, left hemisphere 2.6
1581 Female, age 85, right hemisphere 1.8
1573 Male, age 61, right hemisphere 1.6
1574 Male, age 75, left hemisphere 1.6
1577 Male, age 74, right hemisphere 1.5
1575 Male, age 75, right hemisphere 1.4
1578 Female, age 94, left hemisphere 1.4
1579 Female, age 94, right hemisphere 1.4
1583 Female, age 67, right hemisphere 1.3
1582 Female, age 67, left hemisphere 0.9
Frontomarginal cortex
nTPM: 2.4
1465 Male, age 61, left hemisphere 5.3
1466 Male, age 61, right hemisphere 4.4
1467 Male, age 75, right hemisphere 3.0
1470 Female, age 94, right hemisphere 3.0
1468 Male, age 74, left hemisphere 2.9
1469 Female, age 94, left hemisphere 1.7
1473 Female, age 67, right hemisphere 1.6
1471 Female, age 85, left hemisphere 0.0
1472 Female, age 67, left hemisphere 0.0
Frontopolar cortex
nTPM: 3.2
1459 Male, age 61, right hemisphere 5.5
1458 Male, age 61, left hemisphere 5.0
1464 Female, age 67, right hemisphere 4.7
1460 Male, age 75, left hemisphere 4.2
1461 Male, age 75, right hemisphere 1.9
1462 Female, age 94, left hemisphere 1.1
1463 Female, age 67, left hemisphere 0.0
Gyrus rectus
nTPM: 2.6
1475 Male, age 61, right hemisphere 5.6
1476 Male, age 75, left hemisphere 3.1
1474 Male, age 61, left hemisphere 2.9
1481 Female, age 67, left hemisphere 2.8
1480 Female, age 85, left hemisphere 2.5
1477 Male, age 75, right hemisphere 2.3
1479 Female, age 94, right hemisphere 1.4
1478 Female, age 94, left hemisphere 0.5
Inferior frontal gyrus, orbital
nTPM: 1.4
1508 Female, age 85, right hemisphere 3.3
1501 Male, age 61, right hemisphere 2.8
1500 Male, age 61, left hemisphere 2.4
1502 Male, age 75, left hemisphere 1.9
1503 Male, age 75, right hemisphere 1.6
1506 Female, age 94, left hemisphere 1.2
1505 Male, age 74, right hemisphere 1.0
1504 Male, age 74, left hemisphere 0.1
1507 Female, age 85, left hemisphere 0.0
1509 Female, age 67, right hemisphere 0.0
Inferior frontal gyrus, triangular
nTPM: 1.9
1548 Female, age 85, right hemisphere 3.7
1542 Male, age 61, left hemisphere 2.6
1544 Male, age 75, right hemisphere 2.2
1547 Female, age 85, left hemisphere 1.7
1549 Female, age 67, left hemisphere 1.7
1543 Male, age 61, right hemisphere 1.5
1546 Female, age 94, right hemisphere 1.5
1545 Male, age 74, right hemisphere 0.4
Orbitofrontal gyrus, lateral
nTPM: 2.1
1498 Female, age 85, right hemisphere 3.7
1493 Male, age 61, right hemisphere 3.5
1494 Male, age 75, left hemisphere 2.1
1495 Female, age 94, left hemisphere 1.8
1496 Female, age 94, right hemisphere 1.8
1499 Female, age 67, right hemisphere 1.3
1497 Female, age 85, left hemisphere 0.7
Orbitofrontal gyrus, medial
nTPM: 2.1
1484 Male, age 75, right hemisphere 3.6
1483 Male, age 75, left hemisphere 2.9
1490 Female, age 85, right hemisphere 2.6
1491 Female, age 67, left hemisphere 2.3
1482 Male, age 61, left hemisphere 2.2
1489 Female, age 85, left hemisphere 2.0
1488 Female, age 94, right hemisphere 1.8
1487 Female, age 94, left hemisphere 1.7
1485 Male, age 74, left hemisphere 1.5
1492 Female, age 67, right hemisphere 1.3
1486 Male, age 74, right hemisphere 1.0
Orbitofrontal gyrus, posterior
nTPM: 1.8
1532 Male, age 61, right hemisphere 3.4
1531 Male, age 61, left hemisphere 3.1
1534 Male, age 75, right hemisphere 2.2
1539 Female, age 85, right hemisphere 2.2
1533 Male, age 75, left hemisphere 2.0
1537 Female, age 94, right hemisphere 1.6
1538 Female, age 85, left hemisphere 1.6
1541 Female, age 67, right hemisphere 1.4
1535 Male, age 74, left hemisphere 1.0
1536 Female, age 94, left hemisphere 1.0
1540 Female, age 67, left hemisphere 0.0
Subcallosal gyrus
nTPM: 1.9
1559 Female, age 85, right hemisphere 4.3
1558 Female, age 85, left hemisphere 3.4
1552 Male, age 75, left hemisphere 2.7
1557 Female, age 94, right hemisphere 2.3
1561 Female, age 67, right hemisphere 1.9
1560 Female, age 67, left hemisphere 1.7
1551 Male, age 61, right hemisphere 1.6
1554 Male, age 74, left hemisphere 1.6
1553 Male, age 75, right hemisphere 1.3
1555 Male, age 74, right hemisphere 1.1
1550 Male, age 61, left hemisphere 1.0
1556 Female, age 94, left hemisphere 0.0
Superior frontal gyrus
nTPM: 2.3
1570 Female, age 85, right hemisphere 3.1
1563 Male, age 61, right hemisphere 3.0
1569 Female, age 85, left hemisphere 2.7
1562 Male, age 61, left hemisphere 2.5
1566 Male, age 74, right hemisphere 2.5
1571 Female, age 67, right hemisphere 2.2
1565 Male, age 75, right hemisphere 2.0
1564 Male, age 75, left hemisphere 1.7
1567 Female, age 94, left hemisphere 1.7
1568 Female, age 94, right hemisphere 1.1
Temporal cortex
nTPM: 1.8
1591 Male, age 75, right hemisphere 2.8
1590 Male, age 61, right hemisphere 2.7
1596 Female, age 85, right hemisphere 2.6
1592 Male, age 74, left hemisphere 1.5
1594 Female, age 94, left hemisphere 1.5
1595 Female, age 94, right hemisphere 1.1
1593 Male, age 74, right hemisphere 0.5
Ventrolateral prefrontal cortex
nTPM: 2.3
1451 Male, age 75, right hemisphere 4.0
1456 Female, age 67, left hemisphere 3.1
1455 Female, age 85, right hemisphere 2.7
1454 Female, age 94, left hemisphere 2.1
1457 Female, age 67, right hemisphere 2.1
1453 Male, age 74, right hemisphere 2.0
1452 Male, age 74, left hemisphere 0.0
Ventromedial prefrontal cortex
nTPM: 3.1
1433 Male, age 61, right hemisphere 4.4
1436 Female, age 85, left hemisphere 3.8
1437 Female, age 85, right hemisphere 3.1
1432 Male, age 61, left hemisphere 3.0
1438 Female, age 67, left hemisphere 2.7
1434 Male, age 75, right hemisphere 2.6
1435 Female, age 94, right hemisphere 2.1

CEREBRAL CORTEX - GTEx RNA-seqi
Max subtype nTPMi 5.3
GTEx sample id Sample description nTPM
2.63.65.00.08.3012345678910
Brain - Anterior cingulate cortex (BA24)
Average nTPM: 3.9
Samples: 233

Max nTPM: 10.7
Min nTPM: 0.0
Std nTPM: 1.7
Median nTPM: 3.6
GTEX-N7MS-0011-R3a-SM-33HC6 60-69 years, male 10.7
GTEX-PVOW-0011-R3A-SM-32PKX 40-49 years, male 10.1
GTEX-T2IS-0011-R3A-SM-32QPB 20-29 years, female 9.3
GTEX-YFC4-0011-R3a-SM-4RGLP 40-49 years, female 8.3
GTEX-12126-0011-R3b-SM-GJ3RE 20-29 years, male 8.0
GTEX-14PN4-0011-R3b-SM-686ZU 50-59 years, male 7.8
GTEX-1P4AB-0011-R3a-SM-F33ZW 50-59 years, male 7.6
GTEX-QVUS-0011-R3A-SM-3GAFD 60-69 years, female 7.5
GTEX-12ZZY-0011-R3a-SM-GJ3Q6 60-69 years, male 7.4
GTEX-111FC-0011-R3b-SM-GJ3PN 60-69 years, male 7.3
GTEX-RNOR-0011-R3A-SM-5SI8E 50-59 years, female 7.2
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3.44.65.90.38.001234567891011
Brain - Cortex
Average nTPM: 4.6
Samples: 270

Max nTPM: 11.2
Min nTPM: 0.3
Std nTPM: 1.6
Median nTPM: 4.6
GTEX-PVOW-2526-SM-2XCF7 40-49 years, male 11.2
GTEX-18465-3026-SM-7LG6Y 50-59 years, male 8.0
GTEX-12WSC-3026-SM-5GCNF 50-59 years, male 7.9
GTEX-1AX9I-3026-SM-73KUH 60-69 years, male 7.9
GTEX-WZTO-2926-SM-3NM9I 40-49 years, male 7.8
GTEX-12126-1026-SM-5P9JJ 20-29 years, male 7.7
GTEX-14JG1-3026-SM-5YYAA 40-49 years, male 7.5
GTEX-14JIY-2926-SM-69LPT 60-69 years, male 7.5
GTEX-WVLH-3026-SM-3MJG9 50-59 years, male 7.5
GTEX-1313W-3126-SM-5LZUI 50-59 years, female 7.3
GTEX-1B933-3126-SM-7P8RL 50-59 years, female 7.3
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3.75.26.80.810.1012345678910
Brain - Frontal Cortex (BA9)
Average nTPM: 5.3
Samples: 269

Max nTPM: 10.1
Min nTPM: 0.8
Std nTPM: 1.9
Median nTPM: 5.2
GTEX-PVOW-0011-R10A-SM-EXOHB 40-49 years, male 10.1
GTEX-12WSE-0011-R10b-SM-5P9JV 20-29 years, male 9.5
GTEX-QDT8-0011-R10A-SM-32PKG 30-39 years, female 9.4
GTEX-11OF3-0011-R10b-SM-GI4W3 60-69 years, male 9.2
GTEX-14E6D-0011-R10a-SM-5YY9C 50-59 years, male 9.1
GTEX-14PN4-0011-R10b-SM-69LP2 50-59 years, male 9.1
GTEX-1192X-0011-R10a-SM-DO941 50-59 years, male 9.0
GTEX-145MG-0011-R10a-SM-5PNWG 50-59 years, male 9.0
GTEX-17HG3-0011-R10b-SM-7LT97 30-39 years, female 8.9
GTEX-1313W-0011-R10b-SM-5DUXA 50-59 years, female 8.8
GTEX-1EX96-0011-R10b-SM-CE6QR 50-59 years, male 8.8
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CEREBRAL CORTEX - FANTOM5 CAGEi
Max subtype Scaled Tags Per Millioni 42.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Occipital cortex
Scaled Tags Per Million: 36.9
FF:10163-103B1 76 years, female 36.9
Postcentral gyrus
Scaled Tags Per Million: 21.5
FF:10032-101E5 44-52 years, mixed 21.5
Frontal lobe
Scaled Tags Per Million: 35.4
FF:10040-101F4 32-61 years, mixed 35.4
Insula
Scaled Tags Per Million: 26.4
FF:10039-101F3 20-68 years, mixed 26.4
Medial frontal gyrus
Scaled Tags Per Million: 39.4
FF:10150-102I6 76 years, female 39.4
Medial temporal gyrus
Scaled Tags Per Million: 42.2
FF:10183-103D3 60 years, female 45.2
FF:10156-103A3 76 years, female 39.2
Occipital lobe
Scaled Tags Per Million: 21.5
FF:10076-102A4 27 years, male 21.5
Occipital pole
Scaled Tags Per Million: 23.4
FF:10036-101E9 22-68 years, mixed 23.4
Paracentral gyrus
Scaled Tags Per Million: 26.1
FF:10035-101E8 22-69 years, mixed 26.1
Parietal lobe
Scaled Tags Per Million: 27.8
FF:10157-103A4 76 years, female 34.5
FF:10171-103B9 60 years, female 27.8
FF:10034-101E7 35-89 years, mixed 21.3
Temporal lobe
Scaled Tags Per Million: 20.9
FF:10031-101E4 32-61 years, mixed 20.9

CEREBRAL CORTEX - Mouse RNA-seqi
Max subtype nTPMi 11.4
Mouse sample Sample description nTPM
10.811.311.89.712.60123456789101112
 		Occipital cortex
nTPM: 11.2
Samples: 4

Max nTPM: 12.6
Min nTPM: 9.7
Sample A Male 11.1
Sample B Male 12.6
Sample C Female 11.5
Sample D Female 9.7
10.510.811.310.212.30123456789101112
 		Frontal cortex
nTPM: 11.0
Samples: 4

Max nTPM: 12.3
Min nTPM: 10.2
Sample A Male 12.3
Sample B Male 10.9
Sample C Female 10.6
Sample D Female 10.2
11.211.511.710.711.901234567891011
 		Retrosplenial and cingulate cortex
nTPM: 11.4
Samples: 4

Max nTPM: 11.9
Min nTPM: 10.7
Sample A Male 11.4
Sample B Male 11.9
Sample C Female 10.7
Sample D Female 11.6
10.310.711.110.211.401234567891011
 		Somatosensory cortex
nTPM: 10.7
Samples: 4

Max nTPM: 11.4
Min nTPM: 10.2
Sample A Male 11.4
Sample B Male 11.0
Sample C Female 10.2
Sample D Female 10.3

CEREBRAL CORTEX - Allen Mouse ISHi
Max subtype Expression energyi 0.4
Allen experiment id Experiment description Expression energy
Cerebral cortex
Expression energy: 0.4
69626717 Antisense, RP_050428_01_B12, Mouse strain C57BL/6J (56 days, male) 0.4

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