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                                          • PRKCD
                                          TISSUE PRIMARY DATA ENDOMETRIUM Show tissue menu
                                          ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BLOOD VESSEL BONE MARROW BREAST BRONCHUS CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON
                                          DUODENUM ENDOMETRIUM EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MIDBRAIN
                                          NASOPHARYNX ORAL MUCOSA OVARY PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN
                                          SMALL INTESTINE SMOOTH MUSCLE SOFT TISSUE SPINAL CORD SPLEEN STOMACH TESTIS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA
                                          ANTIBODIES
                                          AND
                                          VALIDATION
                                          Dictionary
                                          Endometrium
                                          Tissue proteome
                                          Endometrium
                                          Tissue methods
                                          ENDOMETRIUM - Expression summary
                                          Protein expression
                                          Endometriumi

                                          On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

                                          h
                                          m
                                          l
                                          n
                                          Cells in endometrial stroma: Not detected
                                          Glandular cells: High
                                          RNA expressioni

                                          A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

                                          Scroll down to view mRNA expression data in more detail.

                                          Consensus:8.6 nTPM
                                          HPA:7.0 nTPM
                                          GTEx:8.6 nTPM
                                          FANTOM5:8.8 Scaled Tags Per Million
                                          ENDOMETRIUM - SINGLE CELL RNA EXPRESSION
                                          Explore single cell type data
                                          Endometrial ciliated cellsEndometrial glandular cellsEndometrial secretory cellsEndometrial luminal cellsVascular endothelial cellsLymphatic endothelial cellsEndometrial stromal cellsMacrophagesT-cellsInnate lymphoid cellsB-cellsPDCsNK-cells0102030405060nCPM

                                          ENDOMETRIUM 1 - Antibody stainingi

                                          Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells. Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.

                                          Ascending and descending describe two types of gradient, based on difference in staining intensity between enterocytes in crypts and apical enterocytes.

                                          Ascending - the staining intensity is stronger in apical enterocytes (towards the lumen) compared to enterocytes in the crypts (gland based)

                                          Descending - the staining is weaker in apical enterocytes compared to enterocytes in crypts

                                          Antibody HPA001863Antibody HPA001890Antibody CAB010469Antibody CAB013225
                                          Cells in endometrial stroma Not detectedNot detectedNot detectedNot detected
                                          Glandular cells MediumMediumMediumHigh








                                          ENDOMETRIUM 2 - Antibody stainingi

                                          Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells. Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.

                                          Ascending and descending describe two types of gradient, based on difference in staining intensity between enterocytes in crypts and apical enterocytes.

                                          Ascending - the staining intensity is stronger in apical enterocytes (towards the lumen) compared to enterocytes in the crypts (gland based)

                                          Descending - the staining is weaker in apical enterocytes compared to enterocytes in crypts

                                          Antibody HPA001863Antibody HPA001890Antibody CAB010469Antibody CAB013225
                                          Cells in endometrial stroma Not detectedNot detectedNot detectedNot detected
                                          Glandular cells HighMediumMediumHigh







                                          ENDOMETRIUM - HPA RNA-seqi

                                          The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.

                                          Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.

                                          Average nTPMi

                                          Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

                                          7.0
                                          overview
                                          Female, age 34
                                          Endometrium sample 113
                                          nTPM: 4.8
                                          Cell types%
                                          Glandular cells:
                                          5

                                          Stromal cells:
                                          25

                                          Smooth muscle cells:
                                          65

                                          Other cell types:
                                          5

                                          overview
                                          Female, age 56
                                          Endometrium sample 114
                                          nTPM: 5.8
                                          Cell types%
                                          Glandular cells:
                                          5

                                          Stromal cells:
                                          15

                                          Smooth muscle cells:
                                          75

                                          Other cell types:
                                          5

                                          overview
                                          Female, age 40
                                          Endometrium sample 268
                                          nTPM: 9.9
                                          Cell types%
                                          Glandular cells:
                                          5

                                          Stromal cells:
                                          20

                                          Smooth muscle cells:
                                          70

                                          Other cell types:
                                          5

                                          overview
                                          Female, age 60
                                          Endometrium sample 297
                                          nTPM: 7.4
                                          Cell types%
                                          Glandular cells:
                                          5

                                          Stromal cells:
                                          20

                                          Smooth muscle cells:
                                          75

                                          Other cell types:
                                          0

                                          overview
                                          Female, age 83
                                          Endometrium sample 301
                                          nTPM: 7.2
                                          Cell types%
                                          Glandular cells:
                                          5

                                          Stromal cells:
                                          10

                                          Smooth muscle cells:
                                          80

                                          Other cell types:
                                          5


                                          ENDOMETRIUM - GTEx RNA-seqi

                                          RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

                                          Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

                                          Max subtype nTPMi

                                          Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

                                          8.6
                                          GTEx sample id Sample description nTPM
                                          7.08.110.15.411.302468101214
                                          7.08.110.15.411.302468101214
                                          Uterus - Endometrium
                                          Average nTPM: 8.6
                                          Samples: 27

                                          Max nTPM: 15.8
                                          Min nTPM: 5.4
                                          Std nTPM: 2.2
                                          Median nTPM: 8.1
                                          GTEX-T6MO-1526-SM-4DM57 40-49 years, female 15.8
                                          GTEX-13VXT-1626-SM-5IJES 20-29 years, female 11.3
                                          GTEX-PWCY-1426-SM-48TCT 20-29 years, female 11.2
                                          GTEX-1HCUA-1226-SM-9WPP5 50-59 years, female 10.9
                                          GTEX-XUZC-0926-SM-4BOQF 30-39 years, female 10.6
                                          GTEX-13QBU-1626-SM-5LU4S 40-49 years, female 10.3
                                          GTEX-T5JW-1526-SM-4DM5E 20-29 years, female 10.1
                                          GTEX-ZVT2-0426-SM-5E44S 50-59 years, female 10.0
                                          GTEX-1MCYP-1226-SM-DTX8H 20-29 years, female 9.6
                                          GTEX-PX3G-2026-SM-48U1H 20-29 years, female 9.6
                                          GTEX-ZTPG-2026-SM-5O999 20-29 years, female 9.0
                                          GTEX-11EM3-1926-SM-5987U 20-29 years, female 8.5
                                          GTEX-ZXES-0726-SM-5E451 30-39 years, female 8.3
                                          GTEX-15SHU-2826-SM-H7OGU 40-49 years, female 8.1
                                          GTEX-S32W-1426-SM-4AD66 50-59 years, female 7.9
                                          GTEX-13D11-1226-SM-5IFGA 50-59 years, female 7.8
                                          GTEX-1CAMS-2026-SM-79395 40-49 years, female 7.7
                                          GTEX-P78B-2526-SM-3P5ZY 40-49 years, female 7.7
                                          GTEX-PWN1-2026-SM-48TD9 40-49 years, female 7.1
                                          GTEX-R55G-1626-SM-48FF4 40-49 years, female 7.0
                                          GTEX-XV7Q-1526-SM-4BRWB 40-49 years, female 7.0
                                          GTEX-1R9PN-0526-SM-DTX86 40-49 years, female 6.7
                                          GTEX-Y114-1826-SM-4TT87 50-59 years, female 6.4
                                          GTEX-1I4MK-1426-SM-B2LWU 50-59 years, female 6.0
                                          GTEX-14BIN-1526-SM-5P9FL 50-59 years, female 5.9
                                          GTEX-U3ZN-0726-SM-4DXT5 30-39 years, female 5.7
                                          GTEX-1B932-2726-SM-731ER 40-49 years, female 5.4
                                          Show allShow less

                                          ENDOMETRIUM - FANTOM5 CAGEi

                                          RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

                                          Max subtype Scaled Tags Per Millioni

                                          Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

                                          8.8
                                          FANTOM5 sample id Sample description Scaled Tags Per Million
                                          Uterus
                                          Scaled Tags Per Million: 8.8
                                          FF:10100-102D1 23-63 years, female 8.8

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