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MPV17L
HPA
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                                          • SUMMARY

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                                          • MPV17L
                                          TISSUE PRIMARY DATA SALIVARY GLAND Show tissue menu
                                          ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BLOOD VESSEL BONE MARROW BREAST BRONCHUS CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON
                                          DUODENUM ENDOMETRIUM EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MIDBRAIN
                                          NASOPHARYNX ORAL MUCOSA OVARY PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN
                                          SMALL INTESTINE SMOOTH MUSCLE SOFT TISSUE SPINAL CORD SPLEEN STOMACH TESTIS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA
                                          ANTIBODIES
                                          AND
                                          VALIDATION
                                          Dictionary
                                          Salivary gland
                                          Tissue proteome
                                          Salivary gland
                                          Tissue methods
                                          SALIVARY GLAND - Expression summary
                                          Protein expression
                                          Salivary glandi

                                          On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

                                          h
                                          m
                                          l
                                          n
                                          Glandular cells: Medium
                                          RNA expressioni

                                          A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

                                          Scroll down to view mRNA expression data in more detail.

                                          Consensus:5.6 nTPM
                                          HPA:1.4 nTPM
                                          GTEx:5.6 nTPM
                                          FANTOM5:11.1 Scaled Tags Per Million
                                          SALIVARY GLAND - SINGLE CELL RNA EXPRESSION
                                          Explore single cell type data
                                          Salivary ionocytesSalivary myoepithelial cellsSalivary duct cellsSalivary basal cellsSalivary acinar cellsVascular endothelial cellsLymphatic endothelial cellsPericytesVascular smooth muscle cellsFibroblastsMast cellsNeutrophilsMonocytesMacrophagesT-cellsInnate lymphoid cellsB-cellsPlasma cellsNK-cells0246810nCPM

                                          SALIVARY GLAND - Antibody stainingi

                                          Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells. Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.

                                          Ascending and descending describe two types of gradient, based on difference in staining intensity between enterocytes in crypts and apical enterocytes.

                                          Ascending - the staining intensity is stronger in apical enterocytes (towards the lumen) compared to enterocytes in the crypts (gland based)

                                          Descending - the staining is weaker in apical enterocytes compared to enterocytes in crypts

                                          Antibody HPA041180
                                          Glandular cells Medium



                                          SALIVARY GLAND - HPA RNA-seqi

                                          The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.

                                          Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.

                                          Average nTPMi

                                          Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

                                          1.4
                                          overview
                                          Female, age 68
                                          Salivary gland sample 216
                                          nTPM: 1.9
                                          Cell types%
                                          Glandular cells:
                                          45

                                          Ductal cells:
                                          25

                                          Adipocytes:
                                          5

                                          Other cell types:
                                          25

                                          overview
                                          Male, age 60
                                          Salivary gland sample 217
                                          nTPM: 0.7
                                          Cell types%
                                          Glandular cells:
                                          55

                                          Ductal cells:
                                          20

                                          Adipocytes:
                                          5

                                          Endothelial cells:
                                          5

                                          Other cell types:
                                          15

                                          overview
                                          Female, age 21
                                          Salivary gland sample 218
                                          nTPM: 1.7
                                          Cell types%
                                          Glandular cells:
                                          55

                                          Ductal cells:
                                          15

                                          Adipocytes:
                                          5

                                          Endothelial cells:
                                          5

                                          Other cell types:
                                          20


                                          SALIVARY GLAND - GTEx RNA-seqi

                                          RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

                                          Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

                                          Max subtype nTPMi

                                          Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

                                          5.6
                                          GTEx sample id Sample description nTPM
                                          2.13.87.60.315.7024681012141618202224
                                          2.13.87.60.315.7024681012141618202224
                                          Minor Salivary Gland
                                          Average nTPM: 5.6
                                          Samples: 181

                                          Max nTPM: 25.0
                                          Min nTPM: 0.3
                                          Std nTPM: 4.9
                                          Median nTPM: 3.8
                                          GTEX-14B4R-1426-SM-5Q5CG 30-39 years, male 25.0
                                          GTEX-14PJN-1726-SM-69LO7 30-39 years, male 24.9
                                          GTEX-1A3MV-1726-SM-72D68 30-39 years, male 21.1
                                          GTEX-1IDJC-1626-SM-AHZ2R 50-59 years, male 20.7
                                          GTEX-11ZTT-2226-SM-5CVLP 60-69 years, female 20.5
                                          GTEX-12WSL-2126-SM-5GCNG 50-59 years, male 18.0
                                          GTEX-ZQUD-2126-SM-51MSY 30-39 years, male 16.9
                                          GTEX-15SHV-2226-SM-6M464 60-69 years, male 16.7
                                          GTEX-13VXT-1726-SM-5IFF5 20-29 years, female 16.2
                                          GTEX-1KD4Q-2526-SM-CXZKL 40-49 years, male 15.7
                                          GTEX-15RJE-2726-SM-6LPJ1 40-49 years, male 15.2
                                          GTEX-146FR-1226-SM-5MR78 60-69 years, female 14.9
                                          GTEX-1B8KZ-1726-SM-73KV7 50-59 years, male 14.5
                                          GTEX-1S82P-0726-SM-EVR4O 60-69 years, female 14.3
                                          GTEX-12WSM-1826-SM-5BC64 60-69 years, male 14.0
                                          GTEX-13QJC-2326-SM-5Q5CD 60-69 years, female 13.1
                                          GTEX-1LC47-2426-SM-DHXKK 60-69 years, male 13.1
                                          GTEX-1R9K4-0526-SM-E76P1 60-69 years, male 12.9
                                          GTEX-1RAZA-0626-SM-EAZ4H 20-29 years, male 12.6
                                          GTEX-13OVL-2926-SM-5IFG3 50-59 years, male 11.3
                                          GTEX-1GTWX-2526-SM-9JGHG 60-69 years, male 11.2
                                          GTEX-WHSB-2326-SM-4M1XK 50-59 years, male 11.1
                                          GTEX-11NV4-1926-SM-5N9D4 60-69 years, male 11.0
                                          GTEX-13O21-1926-SM-5MR39 50-59 years, male 10.9
                                          GTEX-1I6K6-0626-SM-ARU7J 30-39 years, male 10.9
                                          GTEX-1HSGN-0626-SM-A9G2E 40-49 years, female 10.8
                                          GTEX-1HR9M-2526-SM-A9G3J 60-69 years, male 10.5
                                          GTEX-13JVG-2926-SM-5J2N9 60-69 years, male 10.0
                                          GTEX-ZG7Y-2426-SM-DO11H 50-59 years, male 9.9
                                          GTEX-14PN4-2526-SM-686ZG 50-59 years, male 9.8
                                          GTEX-1C4CL-2026-SM-731EB 30-39 years, male 9.8
                                          GTEX-1MCC2-2226-SM-EV7AJ 30-39 years, female 9.8
                                          GTEX-1LVAM-0626-SM-HPAFZ 50-59 years, female 9.7
                                          GTEX-13113-1526-SM-5EGHV 60-69 years, female 9.5
                                          GTEX-1RNSC-2926-SM-EV79L 60-69 years, male 9.4
                                          GTEX-1445S-2926-SM-5O993 60-69 years, male 8.8
                                          GTEX-1J8QM-1826-SM-A96TA 60-69 years, female 8.6
                                          GTEX-1R9PO-2626-SM-E6CPU 60-69 years, female 8.2
                                          GTEX-1GMR2-2026-SM-7MKHK 50-59 years, male 8.1
                                          GTEX-1HGF4-2326-SM-GA91Q 60-69 years, male 8.1
                                          GTEX-1P4AB-2926-SM-EXOJR 50-59 years, male 8.0
                                          GTEX-1AMEY-1126-SM-72D79 30-39 years, female 7.8
                                          GTEX-1KD5A-2226-SM-EV79U 50-59 years, male 7.8
                                          GTEX-1IDJV-2326-SM-GA8ZL 60-69 years, male 7.7
                                          GTEX-1MCQQ-2226-SM-DLHC4 60-69 years, male 7.7
                                          GTEX-1GN1V-2926-SM-9JGI3 60-69 years, male 7.6
                                          GTEX-1HFI7-2426-SM-B2LXV 50-59 years, female 7.4
                                          GTEX-1IKJJ-2826-SM-GA8ZM 60-69 years, male 7.4
                                          GTEX-YJ8A-1826-SM-GNTAB 20-29 years, male 7.3
                                          GTEX-1LKK1-2926-SM-EVR4Z 50-59 years, female 7.0
                                          GTEX-1B8SF-1826-SM-731DJ 60-69 years, male 6.9
                                          GTEX-1J1R8-1826-SM-AHZ3B 40-49 years, male 6.9
                                          GTEX-1H4P4-2026-SM-9WPNV 50-59 years, male 6.8
                                          GTEX-XGQ4-2626-SM-4AT6B 50-59 years, male 6.7
                                          GTEX-18D9U-2226-SM-7KFTN 40-49 years, male 6.6
                                          GTEX-1AX9K-2126-SM-72D7K 50-59 years, male 6.6
                                          GTEX-1GN1W-2526-SM-9JGHX 50-59 years, female 6.6
                                          GTEX-1LSNL-2626-SM-EV7AT 50-59 years, male 6.4
                                          GTEX-11WQK-2926-SM-5EQKT 50-59 years, male 6.3
                                          GTEX-13OVK-1826-SM-6PALE 40-49 years, male 6.3
                                          GTEX-1B97J-2126-SM-79OL6 50-59 years, female 6.3
                                          GTEX-X3Y1-1926-SM-4PQZO 40-49 years, male 6.3
                                          GTEX-X5EB-1726-SM-4E3J7 40-49 years, male 6.2
                                          GTEX-1KANC-1326-SM-CYPT8 50-59 years, female 5.8
                                          GTEX-1LVA9-2526-SM-EVR5H 50-59 years, male 5.7
                                          GTEX-1OJC4-3126-SM-EXOJK 50-59 years, female 5.7
                                          GTEX-131XF-2826-SM-5EGKH 60-69 years, male 5.6
                                          GTEX-1HSMP-1926-SM-GA8Z5 70-79 years, male 5.6
                                          GTEX-WH7G-2126-SM-4M1XU 40-49 years, male 5.6
                                          GTEX-YB5K-1726-SM-5IFIZ 40-49 years, female 5.6
                                          GTEX-11TUW-2426-SM-5EQKB 60-69 years, male 5.5
                                          GTEX-1GZ2Q-2526-SM-9KNVW 40-49 years, male 5.2
                                          GTEX-1HSEH-1826-SM-A96SA 60-69 years, male 5.2
                                          GTEX-W5X1-2426-SM-HPAGA 40-49 years, female 5.1
                                          GTEX-1IY9M-2926-SM-A96TH 60-69 years, male 5.0
                                          GTEX-1JN1M-2426-SM-ARU93 60-69 years, female 5.0
                                          GTEX-1POEN-2226-SM-DPRXV 30-39 years, female 5.0
                                          GTEX-WYVS-2026-SM-4RGNS 40-49 years, female 5.0
                                          GTEX-1HFI6-2826-SM-GA91I 40-49 years, male 4.7
                                          GTEX-1IOXB-2826-SM-AHZ32 50-59 years, male 4.7
                                          GTEX-1RQED-2926-SM-HPAFT 60-69 years, male 4.5
                                          GTEX-13G51-2426-SM-5LZY8 60-69 years, male 4.4
                                          GTEX-14JIY-3026-SM-6EU1R 60-69 years, male 4.3
                                          GTEX-1HSMQ-0926-SM-A96SI 50-59 years, male 4.3
                                          GTEX-111FC-2926-SM-5GZY7 60-69 years, male 4.1
                                          GTEX-YF7O-2226-SM-5CVN8 50-59 years, male 4.1
                                          GTEX-15CHC-1226-SM-686ZH 60-69 years, female 4.0
                                          GTEX-1ICLY-0626-SM-GA915 50-59 years, male 4.0
                                          GTEX-13111-2326-SM-5LZUQ 50-59 years, male 3.9
                                          GTEX-13OVI-2326-SM-5KM47 60-69 years, female 3.8
                                          GTEX-1C6VR-0726-SM-7P8OV 60-69 years, male 3.8
                                          GTEX-1QEPI-0626-SM-E76QE 60-69 years, female 3.8
                                          GTEX-1H1CY-2326-SM-9OSXW 60-69 years, female 3.7
                                          GTEX-1LH75-2726-SM-HL11E 50-59 years, female 3.7
                                          GTEX-1QMI2-0426-SM-EWRND 60-69 years, male 3.6
                                          GTEX-WOFM-2126-SM-4M9R4 20-29 years, male 3.6
                                          GTEX-Y3I4-1926-SM-4TT8L 50-59 years, male 3.6
                                          GTEX-Z9EW-1426-SM-HPAG9 40-49 years, male 3.6
                                          GTEX-1LBAC-0626-SM-D3L9T 20-29 years, male 3.5
                                          GTEX-1NSGN-0626-SM-E9J35 50-59 years, male 3.5
                                          GTEX-14PJ3-1526-SM-664O9 50-59 years, male 3.4
                                          GTEX-15EU6-2626-SM-7KUN4 50-59 years, male 3.4
                                          GTEX-X15G-2126-SM-4PQZR 50-59 years, female 3.4
                                          GTEX-ZP4G-1926-SM-57WDZ 20-29 years, female 3.4
                                          GTEX-1117F-3026-SM-5GZYU 60-69 years, female 3.3
                                          GTEX-18A7B-2826-SM-7KFTK 70-79 years, male 3.1
                                          GTEX-1I4MK-1326-SM-B2LWT 50-59 years, female 3.1
                                          GTEX-13QBU-2126-SM-5KLZN 40-49 years, female 3.0
                                          GTEX-1IE54-0826-SM-AHZ2Z 40-49 years, female 3.0
                                          GTEX-145ME-1626-SM-5RQI3 40-49 years, female 2.9
                                          GTEX-ZE7O-2926-SM-51MSG 50-59 years, female 2.9
                                          GTEX-14E1K-2626-SM-664OJ 50-59 years, male 2.8
                                          GTEX-1CB4I-2526-SM-7MKG1 50-59 years, male 2.8
                                          GTEX-1I1HK-2526-SM-A96SM 60-69 years, male 2.8
                                          GTEX-1NHNU-2226-SM-GRR2I 50-59 years, male 2.7
                                          GTEX-1QP28-2026-SM-F2I3M 50-59 years, female 2.7
                                          GTEX-13CF2-2426-SM-5LZYL 60-69 years, male 2.6
                                          GTEX-1IDJD-2526-SM-C1YSA 30-39 years, male 2.6
                                          GTEX-1R9K5-0626-SM-DPRZB 50-59 years, male 2.6
                                          GTEX-Y111-2626-SM-4TT24 50-59 years, male 2.6
                                          GTEX-11P82-0926-SM-5986X 20-29 years, male 2.5
                                          GTEX-12WSN-2226-SM-5DUXT 40-49 years, male 2.5
                                          GTEX-1339X-2326-SM-5HL5B 40-49 years, male 2.5
                                          GTEX-1J8EW-2826-SM-A96T9 60-69 years, female 2.5
                                          GTEX-ZXG5-2826-SM-5NQ8T 60-69 years, male 2.5
                                          GTEX-178AV-1426-SM-6LLID 40-49 years, male 2.4
                                          GTEX-1C64N-2926-SM-79OLM 50-59 years, male 2.4
                                          GTEX-1MGNQ-1926-SM-DTX8L 40-49 years, male 2.4
                                          GTEX-1QP9N-2026-SM-DPRZT 30-39 years, male 2.3
                                          GTEX-WFJO-2026-SM-4LVM3 30-39 years, male 2.3
                                          GTEX-WY7C-1426-SM-4OND1 50-59 years, male 2.3
                                          GTEX-1314G-2026-SM-5LZUM 30-39 years, male 2.2
                                          GTEX-1AX8Z-0626-SM-731EH 60-69 years, male 2.2
                                          GTEX-1PIEJ-0626-SM-DTX99 20-29 years, female 2.2
                                          GTEX-Y5LM-1826-SM-4VDT9 40-49 years, female 2.1
                                          GTEX-Y5V6-2226-SM-4VDTC 60-69 years, male 2.1
                                          GTEX-1EH9U-2926-SM-7DHLX 60-69 years, male 2.0
                                          GTEX-1LVAO-2626-SM-EVR4S 60-69 years, male 2.0
                                          GTEX-1S5VW-1026-SM-HK797 60-69 years, male 2.0
                                          GTEX-1AYD5-2726-SM-7MXVG 50-59 years, male 1.9
                                          GTEX-1JN6P-2526-SM-CNNPX 60-69 years, male 1.9
                                          GTEX-ZA64-1726-SM-5CVMF 20-29 years, male 1.9
                                          GTEX-ZT9W-2126-SM-51MSF 50-59 years, male 1.9
                                          GTEX-1C64O-0626-SM-7DHL1 60-69 years, male 1.8
                                          GTEX-1QCLZ-2526-SM-EXUST 60-69 years, female 1.8
                                          GTEX-11P81-2026-SM-5P9GT 30-39 years, female 1.7
                                          GTEX-13NYC-2626-SM-5K7VN 60-69 years, male 1.7
                                          GTEX-1GPI7-0326-SM-7MKH6 20-29 years, male 1.7
                                          GTEX-1R9PM-1726-SM-E76T2 20-29 years, male 1.7
                                          GTEX-X261-2426-SM-4PQZU 50-59 years, male 1.7
                                          GTEX-ZC5H-2726-SM-5KLZW 40-49 years, female 1.7
                                          GTEX-1GF9X-0226-SM-7P8SM 40-49 years, female 1.6
                                          GTEX-15SDE-1226-SM-HAV36 50-59 years, female 1.5
                                          GTEX-1I6K7-0926-SM-A96SV 40-49 years, male 1.5
                                          GTEX-11EQ9-2026-SM-5P9JI 30-39 years, male 1.4
                                          GTEX-13NYB-2426-SM-5IFF4 40-49 years, male 1.4
                                          GTEX-18A67-0626-SM-7KFSL 50-59 years, male 1.4
                                          GTEX-XMK1-2626-SM-4B65R 40-49 years, male 1.4
                                          GTEX-11EMC-2526-SM-5PNVU 60-69 years, female 1.2
                                          GTEX-131XH-2626-SM-5GCNP 50-59 years, male 1.2
                                          GTEX-17KNJ-2726-SM-7KFRE 50-59 years, male 1.2
                                          GTEX-ZPU1-2326-SM-57WEP 40-49 years, male 1.1
                                          GTEX-1B932-0626-SM-731EM 40-49 years, female 1.0
                                          GTEX-1PPH8-1526-SM-E6CQO 20-29 years, male 1.0
                                          GTEX-1OJC3-1026-SM-E6CQK 20-29 years, male 0.9
                                          GTEX-1S83E-0626-SM-E9TKC 40-49 years, male 0.9
                                          GTEX-ZLWG-2026-SM-DO11F 50-59 years, female 0.9
                                          GTEX-17MFQ-1626-SM-7938Z 20-29 years, male 0.8
                                          GTEX-18QFQ-0626-SM-718AW 30-39 years, male 0.7
                                          GTEX-1PDJ9-2126-SM-HPAFH 20-29 years, male 0.7
                                          GTEX-XV7Q-2426-SM-4BRV8 40-49 years, female 0.7
                                          GTEX-11ZTS-3026-SM-5EQM7 60-69 years, female 0.6
                                          GTEX-1HCU7-0126-SM-C1YR3 50-59 years, male 0.5
                                          GTEX-1JKYR-0726-SM-AHZ3K 20-29 years, male 0.5
                                          GTEX-1O97I-2826-SM-HPAEO 60-69 years, male 0.5
                                          GTEX-ZAB5-2326-SM-5IJFR 50-59 years, male 0.5
                                          GTEX-ZF29-2126-SM-DNZYX 60-69 years, female 0.5
                                          GTEX-1192X-2926-SM-5N9BA 50-59 years, male 0.4
                                          GTEX-12BJ1-2226-SM-5BC6G 60-69 years, male 0.4
                                          GTEX-ZLFU-2226-SM-EXUS7 40-49 years, male 0.4
                                          GTEX-1S5ZU-0926-SM-HPAEX 20-29 years, female 0.3
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                                          SALIVARY GLAND - FANTOM5 CAGEi

                                          RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

                                          Max subtype Scaled Tags Per Millioni

                                          Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

                                          11.1
                                          FANTOM5 sample id Sample description Scaled Tags Per Million
                                          Parotid gland
                                          Scaled Tags Per Million: 11.1
                                          FF:10199-103F1 23 years, male 11.1
                                          Salivary gland
                                          Scaled Tags Per Million: 6.9
                                          FF:10093-102C3 16-60 years, mixed 6.9
                                          Submaxillary gland
                                          Scaled Tags Per Million: 4.7
                                          FF:10202-103F4 24 years, male 4.7

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