News ArticlesHuman Protein Atlas featured in Nature editorialIn an article in Nature, spatial proteomics was highlighted as a powerful and fast-evolving field - and the Human Protein Atlas was prominently featured as a pioneering initiative in this space. The article explores how researchers are using methods like high-resolution imaging, mass spectrometry, and machine learning in different ways to reveal the dynamic locations of proteins inside human cells...Read more Multiplex tissue image of the month - CFAP45 in endometriumThis month, cilia and flagella associated protein 45 (gene: CFAP45) is highlighted among the sparse population of ciliated cells in endometrial glands through the use of multiplex immunohistochemistry (mIHC/IF)...Read more The multilocalizing proteomeKnowing where proteins are localized in the cell can help map out cellular processes and signaling pathways to better understand the flow of information within and between cells. The subcellular location of a protein is thought to be tightly linked to its function so that a protein in the nucleus may be involved in gene regulation, while one in the mitochondria might play a role in energy production. However, after having studied the subcellular location of the majority of all human proteins it seems that more than half are in fact multilocalizing proteins (MLPs)...Read more |