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MPDU1
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                                          • SUMMARY

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                                          • MPDU1
                                          TISSUE PRIMARY DATA URINARY BLADDER Show tissue menu
                                          ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BLOOD VESSEL BONE MARROW BREAST BRONCHUS CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON
                                          DUODENUM ENDOMETRIUM EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MIDBRAIN
                                          NASOPHARYNX ORAL MUCOSA OVARY PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN
                                          SMALL INTESTINE SMOOTH MUSCLE SOFT TISSUE SPINAL CORD SPLEEN STOMACH TESTIS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA
                                          ANTIBODIES
                                          AND
                                          VALIDATION
                                          Dictionary
                                          Urinary bladder
                                          Tissue proteome
                                          Tissue methods
                                          URINARY BLADDER - Expression summary
                                          Protein expression
                                          Urinary bladderi

                                          On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

                                          h
                                          m
                                          l
                                          n
                                          Urothelial cells: Medium
                                          RNA expressioni

                                          A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

                                          Scroll down to view mRNA expression data in more detail.

                                          Consensus:40.3 nTPM
                                          HPA:40.3 nTPM
                                          GTEx:22.0 nTPM
                                          FANTOM5:22.6 Scaled Tags Per Million
                                          URINARY BLADDER - SINGLE CELL RNA EXPRESSION
                                          Explore single cell type data
                                          Schwann cellsUrothelial cellsSmooth muscle cellsVascular endothelial cellsLymphatic endothelial cellsPericytesVascular smooth muscle cellsFibroblastsMast cellsNeutrophilsMonocytesMacrophagesT-cellsInnate lymphoid cellsB-cellsPlasma cellsNK-cells020406080100120140nCPM

                                          URINARY BLADDER - Antibody stainingi

                                          Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells. Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.

                                          Ascending and descending describe two types of gradient, based on difference in staining intensity between enterocytes in crypts and apical enterocytes.

                                          Ascending - the staining intensity is stronger in apical enterocytes (towards the lumen) compared to enterocytes in the crypts (gland based)

                                          Descending - the staining is weaker in apical enterocytes compared to enterocytes in crypts

                                          Antibody HPA014845
                                          Urothelial cells Medium



                                          URINARY BLADDER - HPA RNA-seqi

                                          The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.

                                          Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.

                                          Average nTPMi

                                          Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

                                          40.3
                                          overview
                                          Male, age 74
                                          Urinary bladder sample 264
                                          nTPM: 26.5
                                          Cell types%
                                          Urothelial cells:
                                          5

                                          Smooth muscle cells:
                                          60

                                          Fibroblasts:
                                          20

                                          Endothelial cells:
                                          10

                                          Other cell types:
                                          5

                                          overview
                                          Male, age 80
                                          Urinary bladder sample 265
                                          nTPM: 40.1
                                          Cell types%
                                          Urothelial cells:
                                          10

                                          Smooth muscle cells:
                                          45

                                          Fibroblasts:
                                          15

                                          Endothelial cells:
                                          10

                                          Other cell types:
                                          20

                                          N/A
                                          Female, age 0.1
                                          Urinary bladder sample 1597
                                          nTPM: 53.1
                                          N/A
                                          Female, age 0.1
                                          Urinary bladder sample 1598
                                          nTPM: 41.6

                                          URINARY BLADDER - GTEx RNA-seqi

                                          RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

                                          Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

                                          Max subtype nTPMi

                                          Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

                                          22.0
                                          GTEx sample id Sample description nTPM
                                          14.721.628.26.747.10510152025303540455055
                                          14.721.628.26.747.10510152025303540455055
                                          Bladder
                                          Average nTPM: 22.0
                                          Samples: 77

                                          Max nTPM: 57.1
                                          Min nTPM: 6.7
                                          Std nTPM: 10.2
                                          Median nTPM: 21.6
                                          GTEX-RUSQ-1326-SM-GQ1EA 50-59 years, male 57.1
                                          GTEX-POMQ-0926-SM-H6Q6H 20-29 years, female 47.1
                                          GTEX-S7SF-1126-SM-GQ1CH 20-29 years, female 43.1
                                          GTEX-P4QT-1926-SM-HAUYQ 50-59 years, female 39.2
                                          GTEX-PWN1-1926-SM-HAUZN 40-49 years, female 37.3
                                          GTEX-OHPL-1926-SM-HAV18 60-69 years, female 36.9
                                          GTEX-Q2AI-1026-SM-GRR3I 40-49 years, male 36.9
                                          GTEX-SNMC-0826-SM-4DM66 20-29 years, male 36.2
                                          GTEX-R53T-1426-SM-H7OG3 50-59 years, female 34.6
                                          GTEX-SNOS-0526-SM-4DM54 40-49 years, male 33.9
                                          GTEX-U3ZN-1226-SM-4DXUD 30-39 years, female 33.7
                                          GTEX-OOBK-1926-SM-HAUZL 40-49 years, male 32.8
                                          GTEX-PWCY-1126-SM-H7OGX 20-29 years, female 32.4
                                          GTEX-T5JW-1026-SM-EZ6LR 20-29 years, female 31.8
                                          GTEX-QDVN-1426-SM-GPRWL 50-59 years, male 30.8
                                          GTEX-S3XE-1226-SM-4AD4L 50-59 years, male 30.8
                                          GTEX-OHPM-1926-SM-H7OG1 50-59 years, male 28.8
                                          GTEX-OIZH-1926-SM-GPRXO 50-59 years, male 28.7
                                          GTEX-T6MO-0926-SM-GPRWN 40-49 years, female 28.6
                                          GTEX-NPJ8-1126-SM-GNTAI 40-49 years, male 28.2
                                          GTEX-S4UY-0926-SM-4AD6O 40-49 years, female 27.9
                                          GTEX-O5YT-1926-SM-H6Q82 20-29 years, male 27.8
                                          GTEX-T8EM-1726-SM-GPRWO 40-49 years, male 27.7
                                          GTEX-QCQG-0826-SM-GPI8H 50-59 years, female 27.4
                                          GTEX-P4PP-1926-SM-HAUZM 30-39 years, female 27.0
                                          GTEX-QV44-1426-SM-GPI8D 50-59 years, male 26.2
                                          GTEX-S33H-1926-SM-EYYVH 30-39 years, male 26.0
                                          GTEX-QMRM-1326-SM-HAUYS 50-59 years, male 25.8
                                          GTEX-T6MN-2226-SM-EVYAM 50-59 years, male 24.1
                                          GTEX-Q2AH-1326-SM-GPRWF 40-49 years, male 23.7
                                          GTEX-S4Q7-0926-SM-4AD5D 20-29 years, male 23.7
                                          GTEX-PW2O-1026-SM-GPRWA 20-29 years, male 23.3
                                          GTEX-QLQW-0826-SM-H7OG2 30-39 years, male 23.3
                                          GTEX-R55G-1326-SM-HAUYU 40-49 years, female 23.2
                                          GTEX-RM2N-1026-SM-GOQY8 50-59 years, male 22.5
                                          GTEX-OIZF-1926-SM-7PBZS 60-69 years, male 22.4
                                          GTEX-PX3G-1926-SM-GQ1ED 20-29 years, female 22.1
                                          GTEX-QEG5-2326-SM-GRR2Z 20-29 years, male 21.8
                                          GTEX-N7MS-2126-SM-GRR2X 60-69 years, male 21.6
                                          GTEX-QLQ7-1226-SM-GOQYE 60-69 years, male 20.6
                                          GTEX-U3ZH-0826-SM-H6Q7I 30-39 years, male 19.6
                                          GTEX-QEG4-2126-SM-GQ1CE 30-39 years, male 19.4
                                          GTEX-S32W-1126-SM-4AD5V 50-59 years, female 18.8
                                          GTEX-R45C-2426-SM-HL11G 60-69 years, female 18.4
                                          GTEX-PLZ5-1326-SM-GQ1C2 50-59 years, male 18.1
                                          GTEX-QDVJ-1526-SM-GPI84 50-59 years, male 18.1
                                          GTEX-P78B-2126-SM-GQ1C3 40-49 years, female 17.8
                                          GTEX-SUCS-1226-SM-GPI9A 70-79 years, male 17.2
                                          GTEX-U4B1-1226-SM-4DXT7 40-49 years, male 17.2
                                          GTEX-RNOR-2126-SM-EXURR 50-59 years, female 16.6
                                          GTEX-OXRK-1926-SM-GRR1N 50-59 years, female 16.1
                                          GTEX-RN64-2426-SM-EZ6L2 50-59 years, male 15.4
                                          GTEX-OIZI-1926-SM-H7OGY 40-49 years, male 15.3
                                          GTEX-P4QS-1926-SM-GQ1BY 60-69 years, male 15.1
                                          GTEX-QXCU-2226-SM-GPI87 50-59 years, male 15.1
                                          GTEX-R55C-1226-SM-GOQY7 40-49 years, male 15.1
                                          GTEX-RWSA-2126-SM-H7OG7 40-49 years, male 14.8
                                          GTEX-N7MT-1826-SM-GQ1C9 60-69 years, female 14.7
                                          GTEX-QDT8-2826-SM-GOQYY 30-39 years, female 14.6
                                          GTEX-P4PQ-1926-SM-GRR14 60-69 years, male 14.0
                                          GTEX-QEL4-1826-SM-EZ6KU 50-59 years, male 13.5
                                          GTEX-OOBJ-1926-SM-GRR1P 60-69 years, male 12.6
                                          GTEX-SE5C-1026-SM-4BRUG 40-49 years, female 12.6
                                          GTEX-TMMY-1526-SM-4DXST 40-49 years, female 12.2
                                          GTEX-U3ZM-0826-SM-4DXU6 40-49 years, male 10.1
                                          GTEX-OHPK-1926-SM-H7OF2 50-59 years, female 9.9
                                          GTEX-QV31-0926-SM-GQ1C6 30-39 years, male 9.9
                                          GTEX-P44H-2226-SM-E9U4P 40-49 years, male 9.5
                                          GTEX-S4P3-0826-SM-H7OF3 50-59 years, female 9.4
                                          GTEX-S95S-0626-SM-EZ6L8 60-69 years, male 9.3
                                          GTEX-T5JC-1126-SM-GPIA1 20-29 years, male 9.3
                                          GTEX-T2IS-2526-SM-GRR23 20-29 years, female 9.1
                                          GTEX-RWS6-1426-SM-GPRWQ 60-69 years, female 8.7
                                          GTEX-TKQ2-0526-SM-GRR15 50-59 years, male 8.5
                                          GTEX-Q734-1226-SM-GRR21 40-49 years, female 8.2
                                          GTEX-PLZ6-1026-SM-GQ1C8 30-39 years, male 7.1
                                          GTEX-REY6-2026-SM-GPRYL 60-69 years, male 6.7
                                          Show allShow less

                                          URINARY BLADDER - FANTOM5 CAGEi

                                          RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

                                          Max subtype Scaled Tags Per Millioni

                                          Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

                                          22.6
                                          FANTOM5 sample id Sample description Scaled Tags Per Million
                                          Bladder
                                          Scaled Tags Per Million: 22.6
                                          FF:10011-101C2 55,58,79 years, mixed 22.6

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