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L3HYPDH
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                                          • L3HYPDH
                                          TISSUE PRIMARY DATA URINARY BLADDER Show tissue menu
                                          ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BLOOD VESSEL BONE MARROW BREAST BRONCHUS CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON
                                          DUODENUM ENDOMETRIUM EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MIDBRAIN
                                          NASOPHARYNX ORAL MUCOSA OVARY PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN
                                          SMALL INTESTINE SMOOTH MUSCLE SOFT TISSUE SPINAL CORD SPLEEN STOMACH TESTIS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA
                                          ANTIBODIES
                                          AND
                                          VALIDATION
                                          Dictionary
                                          Urinary bladder
                                          Tissue proteome
                                          Tissue methods
                                          URINARY BLADDER - Expression summary
                                          Protein expression
                                          Urinary bladderi

                                          On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

                                          h
                                          m
                                          l
                                          n
                                          Urothelial cells: Low
                                          RNA expressioni

                                          A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

                                          Scroll down to view mRNA expression data in more detail.

                                          Consensus:13.7 nTPM
                                          HPA:6.8 nTPM
                                          GTEx:13.7 nTPM
                                          FANTOM5:16.1 Scaled Tags Per Million
                                          URINARY BLADDER - SINGLE CELL RNA EXPRESSION
                                          Explore single cell type data
                                          Schwann cellsUrothelial cellsSmooth muscle cellsVascular endothelial cellsLymphatic endothelial cellsPericytesVascular smooth muscle cellsFibroblastsMast cellsNeutrophilsMonocytesMacrophagesT-cellsInnate lymphoid cellsB-cellsPlasma cellsNK-cells05101520nCPM

                                          URINARY BLADDER - Antibody stainingi

                                          Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells. Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.

                                          Ascending and descending describe two types of gradient, based on difference in staining intensity between enterocytes in crypts and apical enterocytes.

                                          Ascending - the staining intensity is stronger in apical enterocytes (towards the lumen) compared to enterocytes in the crypts (gland based)

                                          Descending - the staining is weaker in apical enterocytes compared to enterocytes in crypts

                                          Antibody HPA056694
                                          Urothelial cells Low


                                          URINARY BLADDER - HPA RNA-seqi

                                          The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.

                                          Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.

                                          Average nTPMi

                                          Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

                                          6.8
                                          overview
                                          Male, age 74
                                          Urinary bladder sample 264
                                          nTPM: 9.6
                                          Cell types%
                                          Urothelial cells:
                                          5

                                          Smooth muscle cells:
                                          60

                                          Fibroblasts:
                                          20

                                          Endothelial cells:
                                          10

                                          Other cell types:
                                          5

                                          overview
                                          Male, age 80
                                          Urinary bladder sample 265
                                          nTPM: 6.2
                                          Cell types%
                                          Urothelial cells:
                                          10

                                          Smooth muscle cells:
                                          45

                                          Fibroblasts:
                                          15

                                          Endothelial cells:
                                          10

                                          Other cell types:
                                          20

                                          N/A
                                          Female, age 0.1
                                          Urinary bladder sample 1597
                                          nTPM: 5.7
                                          N/A
                                          Female, age 0.1
                                          Urinary bladder sample 1598
                                          nTPM: 5.9

                                          URINARY BLADDER - GTEx RNA-seqi

                                          RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

                                          Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

                                          Max subtype nTPMi

                                          Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

                                          13.7
                                          GTEx sample id Sample description nTPM
                                          11.113.516.25.421.6024681012141618202224
                                          11.113.516.25.421.6024681012141618202224
                                          Bladder
                                          Average nTPM: 13.7
                                          Samples: 77

                                          Max nTPM: 25.4
                                          Min nTPM: 5.4
                                          Std nTPM: 3.8
                                          Median nTPM: 13.5
                                          GTEX-T8EM-1726-SM-GPRWO 40-49 years, male 25.4
                                          GTEX-QDT8-2826-SM-GOQYY 30-39 years, female 21.6
                                          GTEX-PLZ6-1026-SM-GQ1C8 30-39 years, male 21.5
                                          GTEX-QXCU-2226-SM-GPI87 50-59 years, male 20.4
                                          GTEX-SUCS-1226-SM-GPI9A 70-79 years, male 20.4
                                          GTEX-PLZ5-1326-SM-GQ1C2 50-59 years, male 20.3
                                          GTEX-SE5C-1026-SM-4BRUG 40-49 years, female 20.2
                                          GTEX-QEG5-2326-SM-GRR2Z 20-29 years, male 19.8
                                          GTEX-P44H-2226-SM-E9U4P 40-49 years, male 19.6
                                          GTEX-TKQ2-0526-SM-GRR15 50-59 years, male 18.4
                                          GTEX-R55C-1226-SM-GOQY7 40-49 years, male 18.3
                                          GTEX-RM2N-1026-SM-GOQY8 50-59 years, male 18.3
                                          GTEX-RWS6-1426-SM-GPRWQ 60-69 years, female 17.8
                                          GTEX-S4P3-0826-SM-H7OF3 50-59 years, female 17.5
                                          GTEX-NPJ8-1126-SM-GNTAI 40-49 years, male 17.0
                                          GTEX-QCQG-0826-SM-GPI8H 50-59 years, female 16.6
                                          GTEX-N7MT-1826-SM-GQ1C9 60-69 years, female 16.5
                                          GTEX-P4QS-1926-SM-GQ1BY 60-69 years, male 16.5
                                          GTEX-T2IS-2526-SM-GRR23 20-29 years, female 16.5
                                          GTEX-REY6-2026-SM-GPRYL 60-69 years, male 16.2
                                          GTEX-TMMY-1526-SM-4DXST 40-49 years, female 16.1
                                          GTEX-PX3G-1926-SM-GQ1ED 20-29 years, female 15.9
                                          GTEX-OIZF-1926-SM-7PBZS 60-69 years, male 15.5
                                          GTEX-QDVN-1426-SM-GPRWL 50-59 years, male 15.2
                                          GTEX-P4QT-1926-SM-HAUYQ 50-59 years, female 15.0
                                          GTEX-QEG4-2126-SM-GQ1CE 30-39 years, male 15.0
                                          GTEX-QDVJ-1526-SM-GPI84 50-59 years, male 14.9
                                          GTEX-OXRK-1926-SM-GRR1N 50-59 years, female 14.5
                                          GTEX-P4PQ-1926-SM-GRR14 60-69 years, male 14.5
                                          GTEX-P78B-2126-SM-GQ1C3 40-49 years, female 14.5
                                          GTEX-T5JC-1126-SM-GPIA1 20-29 years, male 14.5
                                          GTEX-T5JW-1026-SM-EZ6LR 20-29 years, female 14.5
                                          GTEX-QV31-0926-SM-GQ1C6 30-39 years, male 14.2
                                          GTEX-S4UY-0926-SM-4AD6O 40-49 years, female 13.9
                                          GTEX-T6MO-0926-SM-GPRWN 40-49 years, female 13.9
                                          GTEX-PW2O-1026-SM-GPRWA 20-29 years, male 13.8
                                          GTEX-QEL4-1826-SM-EZ6KU 50-59 years, male 13.6
                                          GTEX-U4B1-1226-SM-4DXT7 40-49 years, male 13.6
                                          GTEX-OIZI-1926-SM-H7OGY 40-49 years, male 13.5
                                          GTEX-U3ZM-0826-SM-4DXU6 40-49 years, male 13.1
                                          GTEX-Q2AH-1326-SM-GPRWF 40-49 years, male 12.9
                                          GTEX-RWSA-2126-SM-H7OG7 40-49 years, male 12.9
                                          GTEX-QLQ7-1226-SM-GOQYE 60-69 years, male 12.5
                                          GTEX-PWN1-1926-SM-HAUZN 40-49 years, female 12.1
                                          GTEX-Q734-1226-SM-GRR21 40-49 years, female 12.0
                                          GTEX-R55G-1326-SM-HAUYU 40-49 years, female 11.9
                                          GTEX-R45C-2426-SM-HL11G 60-69 years, female 11.8
                                          GTEX-S33H-1926-SM-EYYVH 30-39 years, male 11.8
                                          GTEX-N7MS-2126-SM-GRR2X 60-69 years, male 11.7
                                          GTEX-QLQW-0826-SM-H7OG2 30-39 years, male 11.7
                                          GTEX-OHPK-1926-SM-H7OF2 50-59 years, female 11.4
                                          GTEX-S32W-1126-SM-4AD5V 50-59 years, female 11.4
                                          GTEX-S95S-0626-SM-EZ6L8 60-69 years, male 11.4
                                          GTEX-RN64-2426-SM-EZ6L2 50-59 years, male 11.3
                                          GTEX-OOBK-1926-SM-HAUZL 40-49 years, male 11.2
                                          GTEX-OOBJ-1926-SM-GRR1P 60-69 years, male 11.1
                                          GTEX-P4PP-1926-SM-HAUZM 30-39 years, female 11.1
                                          GTEX-QMRM-1326-SM-HAUYS 50-59 years, male 11.1
                                          GTEX-S4Q7-0926-SM-4AD5D 20-29 years, male 11.1
                                          GTEX-U3ZH-0826-SM-H6Q7I 30-39 years, male 10.9
                                          GTEX-Q2AI-1026-SM-GRR3I 40-49 years, male 10.8
                                          GTEX-QV44-1426-SM-GPI8D 50-59 years, male 10.7
                                          GTEX-OHPM-1926-SM-H7OG1 50-59 years, male 10.5
                                          GTEX-RNOR-2126-SM-EXURR 50-59 years, female 10.5
                                          GTEX-RUSQ-1326-SM-GQ1EA 50-59 years, male 10.5
                                          GTEX-OIZH-1926-SM-GPRXO 50-59 years, male 10.1
                                          GTEX-S7SF-1126-SM-GQ1CH 20-29 years, female 9.7
                                          GTEX-T6MN-2226-SM-EVYAM 50-59 years, male 9.6
                                          GTEX-POMQ-0926-SM-H6Q6H 20-29 years, female 9.2
                                          GTEX-OHPL-1926-SM-HAV18 60-69 years, female 8.8
                                          GTEX-PWCY-1126-SM-H7OGX 20-29 years, female 8.8
                                          GTEX-SNMC-0826-SM-4DM66 20-29 years, male 8.6
                                          GTEX-SNOS-0526-SM-4DM54 40-49 years, male 8.3
                                          GTEX-O5YT-1926-SM-H6Q82 20-29 years, male 7.9
                                          GTEX-R53T-1426-SM-H7OG3 50-59 years, female 7.7
                                          GTEX-U3ZN-1226-SM-4DXUD 30-39 years, female 7.4
                                          GTEX-S3XE-1226-SM-4AD4L 50-59 years, male 5.4
                                          Show allShow less

                                          URINARY BLADDER - FANTOM5 CAGEi

                                          RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

                                          Max subtype Scaled Tags Per Millioni

                                          Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

                                          16.1
                                          FANTOM5 sample id Sample description Scaled Tags Per Million
                                          Bladder
                                          Scaled Tags Per Million: 16.1
                                          FF:10011-101C2 55,58,79 years, mixed 16.1

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