MIDBRAIN - Expression summary
Protein expressioni No data
RNA expressioni
Consensus:38.4 nTPM
HPA Brain:134.3 nTPM
GTEx:38.4 nTPM
FANTOM5:63.6 Scaled Tags Per Million
Pig:99.2 nTPM
Mouse:142.2 nTPM
Allen mouse:6.8 Expression energy
BRAIN - SINGLE CELL RNA EXPRESSION
Brain excitatory neuronsBrain inhibitory neuronsOther brain neuronsAstrocytesBergmann gliaOligodendrocyte progenitor cellsOligodendrocytesMicrogliaEpendymal cellsChoroid plexus epithelial cellsVascular endothelial cellsPericytesVascular smooth muscle cellsFibroblastsMonocytesMacrophagesT-cellsB-cellsNK-cells0100200300400nCPM

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi 134.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 116.5
2586 Male, age 75, left hemisphere 127.6
2828 Female, age 72, unknown 125.6
2411 Female, age 72, unknown 124.8
1830 Male, age 51, unknown 123.0
2019 Male, age 18, unknown 120.3
1833 Male, age 53, unknown 114.9
1870 Female, age 42, unknown 111.1
1827 Male, age 72, unknown 110.9
2666 Male, age 74, left hemisphere 107.6
2219 Male, age 76, both hemispheres 99.4
Dorsal raphe nucleus
nTPM: 130.9
2298 Female, age 72, unknown 154.9
1828 Male, age 53, unknown 130.8
2047 Male, age 72, unknown 125.8
2750 Male, age 76, both hemispheres 124.6
2016 Female, age 72, unknown 118.5
Inferior colliculus
nTPM: 112.7
2097 Female, age 72, unknown 120.9
1890 Male, age 53, unknown 117.5
1848 Female, age 42, unknown 111.7
2849 Male, age 72, unknown 100.9
Median raphe nucleus
nTPM: 134.3
2220 Male, age 76, midline 134.3
Periaquaductal grey, anterior
nTPM: 116.9
1795 Male, age 51, unknown 118.1
1947 Male, age 18, unknown 116.5
2502 Female, age 75, unknown 116.0
Periaquaductal grey, dorsal
nTPM: 131.0
2850 Male, age 76, both hemispheres 186.7
1831 Male, age 72, unknown 125.0
2464 Female, age 72, unknown 108.9
1840 Male, age 53, unknown 103.5
Periaquaductal grey, lateral
nTPM: 120.1
2140 Male, age 76, both hemispheres 147.2
2272 Male, age 74, both hemispheres 114.0
2053 Male, age 18, unknown 99.0
Pretectal area
nTPM: 117.6
2273 Male, age 74, both hemispheres 137.9
1817 Female, age 42, unknown 132.4
2007 Male, age 72, unknown 132.1
1815 Male, age 53, unknown 127.1
2224 Female, age 72, unknown 122.6
1816 Male, age 51, unknown 115.1
2825 Male, age 18, unknown 110.3
2667 Female, age 75, unknown 110.2
2316 Male, age 76, right hemisphere 110.1
1944 Female, age 72, unknown 109.6
2407 Male, age 75, both hemispheres 86.6
Red nucleus
nTPM: 128.3
1821 Female, age 72, unknown 144.7
1904 Male, age 53, unknown 139.8
1865 Male, age 51, unknown 135.8
2725 Female, age 75, unknown 135.7
2785 Male, age 18, unknown 132.3
1954 Female, age 42, unknown 131.5
2227 Male, age 72, unknown 128.7
2769 Male, age 72, unknown 128.5
2503 Female, age 72, unknown 128.1
2823 Male, age 76, right hemisphere 125.3
2584 Male, age 75, left hemisphere 107.6
2588 Male, age 74, left hemisphere 101.1
Substantia nigra
nTPM: 132.5
1916 Female, age 42, unknown 152.8
2241 Male, age 72, unknown 143.6
1851 Male, age 51, unknown 143.1
2699 Male, age 18, unknown 141.9
1941 Male, age 53, unknown 137.6
2409 Female, age 72, unknown 129.4
1889 Female, age 72, unknown 129.0
2583 Male, age 75, right hemisphere 128.7
2590 Female, age 75, unknown 115.0
2665 Male, age 74, both hemispheres 103.7
Superior colliculus
nTPM: 112.2
2668 Female, age 75, unknown 128.5
2087 Female, age 72, unknown 123.1
2261 Male, age 18, unknown 122.8
1796 Male, age 53, unknown 118.3
1913 Female, age 42, unknown 112.3
1995 Male, age 72, unknown 110.0
2587 Male, age 74, left hemisphere 106.0
1895 Male, age 76, right hemisphere 104.3
2664 Male, age 75, both hemispheres 101.1
1839 Male, age 51, unknown 95.9
Ventral tegmental area
nTPM: 122.0
1915 Female, age 42, unknown 136.8
2218 Male, age 76, both hemispheres 129.2
2223 Female, age 72, unknown 126.6
1942 Male, age 51, unknown 116.3
2410 Female, age 72, unknown 113.5
2021 Male, age 53, unknown 109.5

MIDBRAIN - GTEx RNA-seqi
Max subtype nTPMi 38.4
GTEx sample id Sample description nTPM
34.237.442.126.753.8051015202530354045505560
Brain - Substantia nigra
Average nTPM: 38.4
Samples: 183

Max nTPM: 63.3
Min nTPM: 21.8
Std nTPM: 6.3
Median nTPM: 37.4
GTEX-1CB4J-0011-R2a-SM-9WG5N 60-69 years, male 63.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 57.6
GTEX-1O9I2-0011-R2b-SM-F3K53 50-59 years, male 55.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 55.4
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 53.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 53.3
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 50.7
GTEX-1LKK1-0011-R2b-SM-G8OLT 50-59 years, female 50.7
GTEX-1JN1M-0011-R2b-SM-G9EPE 60-69 years, female 50.2
GTEX-12696-0011-R2b-SM-GHWPY 60-69 years, male 50.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 47.8
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MIDBRAIN - FANTOM5 CAGEi
Max subtype Scaled Tags Per Millioni 63.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 63.6
FF:10158-103A5 76 years, female 63.6

MIDBRAIN - Pig RNA-seqi
Max subtype nTPMi 99.2
Pig sample Sample description nTPM
88.090.695.886.1105.80102030405060708090100
 		Substantia nigra
nTPM: 93.3
Samples: 4

Max nTPM: 105.8
Min nTPM: 86.1
Sample A Female 105.8
Sample B Female 92.4
Sample C Male 88.7
Sample D Male 86.1
85.791.7105.175.294.10102030405060708090100110120130
 		Midbrain
nTPM: 99.2
Samples: 4

Max nTPM: 138.1
Min nTPM: 75.2
Sample A Female 138.1
Sample B Female 94.1
Sample C Male 89.2
Sample D Male 75.2
84.388.590.080.191.50102030405060708090
 		Periaqueductal gray
nTPM: 86.7
Samples: 3

Max nTPM: 91.5
Min nTPM: 80.1
Sample B Female 88.5
Sample C Male 91.5
Sample D Male 80.1
90.594.295.493.596.70102030405060708090
 		Superior colliculi
nTPM: 91.6
Samples: 4

Max nTPM: 96.7
Min nTPM: 81.4
Sample A Female 96.7
Sample B Female 93.5
Sample C Male 94.9
Sample D Male 81.4

MIDBRAIN - Mouse RNA-seqi
Max subtype nTPMi 142.2
Mouse sample Sample description nTPM
140.1142.3144.4136.0148.2020406080100120140
 		Midbrain
nTPM: 142.2
Samples: 4

Max nTPM: 148.2
Min nTPM: 136.0
Sample A Male 136.0
Sample B Male 143.2
Sample C Female 148.2
Sample D Female 141.4

MIDBRAIN - Allen Mouse ISHi
Max subtype Expression energyi 6.8
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 6.8
74658110 Antisense, RP_060220_02_C06, Mouse strain C57BL/6J (56 days, male) 6.8
641530 Antisense, RP_040914_01_E10, Mouse strain C57BL/6J (56 days, male) 6.7

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