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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Glial cells:
Not detected
Neuronal cells:
Medium
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
54751.7
nTPM
HPA Brain:
22494.4
nTPM
GTEx:
54751.7
nTPM
Pig:
11371.5
nTPM
Mouse:
15892.4
nTPM
Allen mouse:
23.5
Expression energy
HIPPOCAMPUS - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA068400
Antibody CAB032215
Glial cells
Low
Not detected
Neuronal cells
Medium
Medium
HIPPOCAMPAL FORMATION - HPA Brain RNA-seq
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
22494.4
Sample id
Sample description
nTPM
Hippocampus nTPM: 22226.2
2621
Female, age 67, right hemisphere
34629.9
1855
Male, age 76, left hemisphere
28036.1
2529
Female, age 94, left hemisphere
24748.8
2148
Female, age 91, left hemisphere
19370.3
1911
Female, age 85, right hemisphere
15673.9
1898
Male, age 80, left hemisphere
10898.2
Dentate gyrus nTPM: 18910.0
2530
Female, age 94, left hemisphere
34499.5
2531
Female, age 67, both hemispheres
29243.8
2246
Female, age 85, both hemispheres
19021.5
2010
Male, age 76, both hemispheres
12408.3
2528
Male, age 74, both hemispheres
9412.2
1927
Female, age 91, both hemispheres
8874.5
Entorhinal gyrus nTPM: 13805.0
2686
Male, age 75, right hemisphere
25026.3
2613
Female, age 94, left hemisphere
18724.2
2117
Female, age 91, right hemisphere
11074.2
1938
Female, age 85, left hemisphere
10104.7
1787
Male, age 76, left hemisphere
9409.4
2764
Male, age 80, right hemisphere
8490.9
Hippocampus, CA1 nTPM: 12863.0
2527
Male, age 74, both hemispheres
16800.7
2045
Male, age 76, both hemispheres
13665.7
1873
Female, age 85, both hemispheres
12980.3
2749
Male, age 80, left hemisphere
12966.4
2082
Female, age 91, right hemisphere
7901.6
Hippocampus, CA2 nTPM: 13785.5
2437
Female, age 94, left hemisphere
25657.8
1892
Male, age 76, both hemispheres
17829.4
1963
Male, age 80, left hemisphere
11762.6
1940
Female, age 85, left hemisphere
10514.7
2113
Female, age 91, right hemisphere
10036.0
2249
Male, age 74, both hemispheres
6912.6
Hippocampus, CA3 nTPM: 22494.4
2861
Female, age 67, both hemispheres
61698.1
2620
Female, age 94, left hemisphere
18445.4
1867
Male, age 76, both hemispheres
17306.4
2137
Male, age 80, left hemisphere
14745.4
1891
Female, age 85, both hemispheres
11583.8
2436
Male, age 74, both hemispheres
11187.2
Parahippocampal cortex nTPM: 16203.0
2622
Female, age 67, right hemisphere
26926.4
2245
Female, age 91, both hemispheres
25953.2
2692
Male, age 74, both hemispheres
22153.8
2532
Female, age 72, left hemisphere
19509.1
2018
Male, age 76, both hemispheres
16047.6
2693
Female, age 94, both hemispheres
13692.5
2250
Female, age 67, right hemisphere
12617.5
1933
Female, age 85, both hemispheres
9104.0
1850
Male, age 80, both hemispheres
8807.1
1990
Female, age 91, right hemisphere
7218.2
Perirhinal gyrus nTPM: 8907.0
2848
Male, age 76, right hemisphere
11643.7
2521
Female, age 94, right hemisphere
9645.9
1841
Female, age 85, right hemisphere
9150.6
1847
Female, age 91, left hemisphere
7347.5
1794
Male, age 80, right hemisphere
6747.4
Subiculum nTPM: 15425.0
2438
Female, age 94, left hemisphere
30710.1
2619
Male, age 74, both hemispheres
16827.5
2042
Male, age 76, both hemispheres
16560.0
1901
Male, age 80, both hemispheres
10810.7
1977
Female, age 85, both hemispheres
9832.2
2729
Female, age 91, right hemisphere
7809.7
HIPPOCAMPAL FORMATION - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
54751.7
GTEx sample id
Sample description
nTPM
Brain - Hippocampus Average nTPM: 54751.7
Samples: 197
Max nTPM: 245152.6
Min nTPM: 3404.6
Std nTPM: 41049.5
Median nTPM: 42084.2
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
15892.4
Mouse sample
Sample description
nTPM
Entorhinal cortex nTPM: 15892.4
Samples: 4
Max nTPM: 16716.9
Min nTPM: 13814.9
Sample A
Male
16715.9
Sample B
Male
13814.9
Sample C
Female
16716.9
Sample D
Female
16321.9
Hippocampal formation nTPM: 13863.4
Samples: 4
Max nTPM: 16020.4
Min nTPM: 12380.8
Sample A
Male
16020.4
Sample B
Male
13228.4
Sample C
Female
13823.8
Sample D
Female
12380.8
HIPPOCAMPAL FORMATION - Allen Mouse ISHi
In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.
Max subtype Expression energyi
Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.