Expression of LPA in testis cancer - The Human Protein Atlas

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LPA

Search result

Field

Cluster

Pathway

SUMMARY

TISSUE

BRAIN

SINGLE CELL

SUBCELL

CANCER

BLOOD

CELL LINE

STRUCT & INT

LPA

TESTICULAR GERM CELL TUMOR (TCGA) - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

Survival analysis data not available.

TCGA RNA samplesⁱ

Average TPM

0.0

Number of samples

133

Samples

Sample	Description	TPM
TCGA-2G-AAGX-01A	0 years, male, white, stage:Stage IA, alive, 5514 days	1.2
TCGA-SN-A84W-01A	0 years, male, white, stage:Stage IS, alive, 293 days	1.2
TCGA-2G-AAG6-01A	0 years, male, white, stage:Stage IS, alive, 2231 days	0.8
TCGA-2G-AAH3-01A	0 years, male, white, stage:Stage I, alive, 1822 days	0.8
TCGA-2G-AAGI-01A	0 years, male, white, stage:Stage IS, alive, 3137 days	0.6
TCGA-2G-AAFJ-01A	0 years, male, asian, stage:'--, alive, 792 days	0.5
TCGA-2G-AAGV-01A	0 years, male, white, stage:'--, alive, 4527 days	0.4
TCGA-2G-AAL5-01A	0 years, male, white, stage:Stage I, alive, 7437 days	0.3
TCGA-2G-AAFZ-01A	0 years, male, white, stage:Stage III, alive, 1353 days	0.3
TCGA-XE-AAOJ-01A	0 years, male, white, stage:Stage IS, alive, 1550 days	0.3
TCGA-YU-A94D-01A	0 years, male, stage:Stage IIIB, alive, 2167 days	0.3
TCGA-2G-AAGC-01A	0 years, male, white, stage:Stage IS, alive, 2585 days	0.2
TCGA-S6-A8JW-01A	0 years, male, white, stage:Stage IS, alive, 698 days	0.2
TCGA-XE-A8H5-01A	0 years, male, stage:Stage IS, alive, 1217 days	0.2
TCGA-2G-AAFH-01A	0 years, male, white, stage:Stage IIB, alive, 1375 days	0.2
TCGA-2G-AAGY-01A	0 years, male, white, stage:Stage IS, alive, 5329 days	0.2
TCGA-YU-A90Q-01A	0 years, male, stage:Stage IB, alive, 1964 days	0.2
TCGA-2G-AAH2-01A	0 years, male, white, stage:Stage IS, alive, 6060 days	0.2
TCGA-XE-AAOC-01A	0 years, male, white, stage:Stage IA, alive, 270 days	0.2
TCGA-2G-AAEW-01A	0 years, male, white, stage:Stage IS, dead, 618 days	0.2
TCGA-XE-AAO3-01A	0 years, male, asian, stage:Stage I, alive, 2857 days	0.2
TCGA-2G-AAF8-01A	0 years, male, white, stage:Stage IA, alive, 3911 days	0.2
TCGA-VF-A8AA-01A	0 years, male, white, stage:Stage I, alive, 1146 days	0.1
TCGA-2X-A9D6-01A	0 years, male, white, stage:Stage I, alive, 607 days	0.1
TCGA-YU-A90P-01A	0 years, male, white, stage:Stage IA, alive, 2069 days	0.1
TCGA-2G-AAF4-01A	0 years, male, white, stage:Stage I, alive, 2315 days	0.1
TCGA-2G-AAF1-01A	0 years, male, asian, stage:Stage IS, alive, 1403 days	0.1
TCGA-2G-AAG7-01A	0 years, male, white, stage:Stage IS, alive, 2475 days	0.1
TCGA-ZM-AA0D-01A	0 years, male, white, stage:Stage IA, alive, 848 days	0.1
TCGA-2G-AAGM-01A	0 years, male, white, stage:Stage IS, alive, 3891 days	0.1
TCGA-2G-AAKH-01A	0 years, male, white, stage:Stage II, alive, 6862 days	0.1
TCGA-2G-AAGP-01A	0 years, male, white, stage:Stage IIA, alive, 4018 days	0.1
TCGA-2G-AAGK-01A	0 years, male, white, stage:Stage IS, alive, 3621 days	0.1
TCGA-XE-AAO4-01A	0 years, male, white, stage:Stage IA, alive, 367 days	0.1
TCGA-XE-AANI-01A	0 years, male, white, stage:Stage IS, alive, 1041 days	0.1
TCGA-XE-A8H1-01A	0 years, male, white, stage:Stage IS, alive, 209 days	0.1
TCGA-2G-AAG3-01A	0 years, male, white, stage:Stage IS, alive, 1593 days	0.1
TCGA-2G-AAH4-01A	0 years, male, white, stage:Stage II, alive, 6210 days	0.1
TCGA-2G-AAG5-01A	0 years, male, white, stage:Stage IS, alive, 2299 days	0.1
TCGA-XE-AAOL-01A	0 years, male, black or african american, stage:Stage I, alive, 13 days	0.1
TCGA-2G-AAGO-01A	0 years, male, white, stage:Stage IS, alive, 4026 days	0.1
TCGA-2G-AAH0-01A	0 years, male, white, stage:Stage IS, alive, 5477 days	0.1
TCGA-YU-A912-01A	0 years, male, black or african american, stage:Stage IIIC, alive, 866 days	0.1
TCGA-WZ-A7V4-01A	0 years, male, white, stage:Stage I, alive, 894 days	0.1
TCGA-WZ-A7V5-01A	0 years, male, white, stage:Stage I, alive, 1061 days	0.1
TCGA-2G-AAHA-01A	0 years, male, white, stage:Stage IB, alive, 3349 days	0.1
TCGA-SB-A6J6-01A	0 years, male, white, stage:Stage IA, alive, 413 days	0.1
TCGA-2G-AAG0-01A	0 years, male, white, stage:Stage IS, alive, 1529 days	0.0
TCGA-2G-AAFY-01A	0 years, male, white, stage:Stage IIA, alive, 1099 days	0.0
TCGA-2G-AAHP-01A	0 years, male, white, stage:Stage IS, alive, 5667 days	0.0
TCGA-ZM-AA06-01A	0 years, male, white, stage:Stage IB, alive, 1498 days	0.0
TCGA-2G-AAGG-01A	0 years, male, white, stage:Stage IIIC, alive, 2611 days	0.0
TCGA-2G-AAG9-01A	0 years, male, white, stage:Stage IIIB, alive, 2234 days	0.0
TCGA-2G-AAHG-01A	0 years, male, white, stage:Stage I, alive, 1819 days	0.0
TCGA-WZ-A8D5-01A	0 years, male, white, stage:'--, alive, 774 days	0.0
TCGA-VF-A8AE-01A	0 years, male, white, stage:Stage IA, alive, 727 days	0.0
TCGA-XE-A8H4-01A	0 years, male, white, stage:Stage IA, alive, 559 days	0.0
TCGA-XE-AAOD-01A	0 years, male, white, stage:Stage IB, alive, 2058 days	0.0
TCGA-W4-A7U4-01A	0 years, male, white, stage:'--, alive, 738 days	0.0
TCGA-2G-AAFI-01A	0 years, male, white, stage:Stage IB, alive, 675 days	0.0
TCGA-YU-A90W-01A	0 years, male, white, stage:Stage IA, alive, 1113 days	0.0
TCGA-2G-AAGZ-01A	0 years, male, white, stage:Stage IIIA, alive, 5233 days	0.0
TCGA-YU-A90Y-01A	0 years, male, black or african american, stage:Stage IIIC, dead, 17 days	0.0
TCGA-SO-A8JP-01A	0 years, male, white, stage:Stage I, alive, 540 days	0.0
TCGA-2G-AAGJ-01A	0 years, male, black or african american, stage:Stage IA, alive, 2938 days	0.0
TCGA-VF-A8AC-01A	0 years, male, white, stage:Stage IA, alive, 1083 days	0.0
TCGA-XE-AAOB-01A	0 years, male, white, stage:Stage IS, dead, 513 days	0.0
TCGA-2G-AAFO-01A	0 years, male, white, stage:Stage IIA, alive, 685 days	0.0
TCGA-ZM-AA0B-01A	0 years, male, white, stage:Stage IA, alive, 838 days	0.0
TCGA-ZM-AA0N-01A	0 years, male, white, stage:Stage IB, alive, 634 days	0.0
TCGA-SN-A84X-01A	0 years, male, white, stage:Stage IS, alive, 312 days	0.0
TCGA-2G-AAHN-01A	0 years, male, white, stage:Stage I, alive, 6445 days	0.0
TCGA-XE-AAO6-01A	0 years, male, white, stage:Stage IA, alive, 240 days	0.0
TCGA-XE-AANV-01A	0 years, male, stage:Stage IB, alive, 1701 days	0.0
TCGA-VF-A8AD-01A	0 years, male, white, stage:Stage IB, alive, 1006 days	0.0
TCGA-2G-AAHL-01A	0 years, male, white, stage:Stage I, alive, 7081 days	0.0
TCGA-VF-A8A9-01A	0 years, male, white, stage:Stage IA, alive, 1119 days	0.0
TCGA-2G-AAFG-01A	0 years, male, white, stage:Stage IS, alive, 6183 days	0.0
TCGA-VF-A8A8-01A	0 years, male, white, stage:Stage IA, alive, 1131 days	0.0
TCGA-W4-A7U2-01A	0 years, male, white, stage:'--, alive, 1263 days	0.0
TCGA-2G-AAFM-01A	0 years, male, white, stage:Stage IIA, alive, 503 days	0.0
TCGA-ZM-AA0H-01A	0 years, male, white, stage:Stage IS, alive, 1736 days	0.0
TCGA-2X-A9D5-01A	0 years, male, white, stage:Stage I, alive, 435 days	0.0
TCGA-2G-AAF6-01A	0 years, male, white, stage:Stage IS, alive, 3491 days	0.0
TCGA-2G-AAFN-01A	0 years, male, white, stage:Stage IIIB, alive, 773 days	0.0
TCGA-4K-AA1H-01A	0 years, male, white, stage:Stage IA, alive, 518 days	0.0
TCGA-YU-A90S-01A	0 years, male, white, stage:Stage IA, alive, 971 days	0.0
TCGA-2G-AALP-01A	0 years, male, white, stage:Stage IIIB, alive, 2645 days	0.0
TCGA-S6-A8JY-01A	0 years, male, white, stage:Stage IS, alive, 278 days	0.0
TCGA-2G-AAGT-01A	0 years, male, white, stage:Stage IS, alive, 4406 days	0.0
TCGA-2G-AAFE-01A	0 years, male, white, stage:Stage IIA, alive, 4702 days	0.0
TCGA-2G-AAGS-01A	0 years, male, white, stage:Stage IIIB, alive, 4816 days	0.0
TCGA-2G-AAGW-01A	0 years, male, white, stage:Stage IS, alive, 4899 days	0.0
TCGA-SN-A6IS-01A	0 years, male, white, stage:Stage IS, alive, 496 days	0.0
TCGA-4K-AAAL-01A	0 years, male, white, stage:Stage IS, alive, 483 days	0.0
TCGA-2G-AAHC-01A	0 years, male, white, stage:Stage IS, alive, 5539 days	0.0
TCGA-XY-A89B-01A	0 years, male, white, stage:Stage IA, alive, 471 days	0.0
TCGA-YU-A94I-01A	0 years, male, stage:Stage IA, alive, 536 days	0.0
TCGA-4K-AA1G-01A	0 years, male, white, stage:Stage IS, alive, 436 days	0.0
TCGA-XY-A9T9-01A	0 years, male, white, stage:Stage IS, alive, 281 days	0.0
TCGA-2G-AAKD-01A	0 years, male, white, stage:Stage III, alive, 6340 days	0.0
TCGA-W4-A7U3-01A	0 years, male, white, stage:'--, alive, 149 days	0.0
TCGA-2G-AAKG-01A	0 years, male, white, stage:Stage I, alive, 6598 days	0.0
TCGA-SB-A76C-01A	0 years, male, white, stage:'--, alive, 42 days	0.0
TCGA-2G-AAKM-01A	0 years, male, white, stage:Stage II, dead, 6972 days	0.0
TCGA-2G-AAKL-01A	0 years, male, white, stage:Stage II, alive, 7023 days	0.0
TCGA-XE-AANR-01A	0 years, male, white, stage:Stage I, alive, 14 days	0.0
TCGA-SN-A84Y-01A	0 years, male, white, stage:Stage IS, alive, 524 days	0.0
TCGA-S6-A8JX-01A	0 years, male, white, stage:Stage IB, alive, 552 days	0.0
TCGA-2G-AAL7-01A	0 years, male, white, stage:Stage IS, alive, 3991 days	0.0
TCGA-2G-AAGA-01A	0 years, male, white, stage:Stage IIA, alive, 2439 days	0.0
TCGA-XE-AANJ-01A	0 years, male, white, stage:Stage IS, alive, 2007 days	0.0
TCGA-2G-AAFV-01A	0 years, male, white, stage:Stage IS, alive, 1389 days	0.0
TCGA-XE-AAOF-01A	0 years, male, asian, stage:Stage IA, alive, 1268 days	0.0
TCGA-2G-AAEX-01A	0 years, male, white, stage:Stage IS, alive, 1259 days	0.0
TCGA-ZM-AA05-01A	0 years, male, white, stage:Stage IIC, alive, 1126 days	0.0
TCGA-2G-AAH8-01A	0 years, male, white, stage:Stage IIIC, alive, 2248 days	0.0
TCGA-2G-AAG8-01A	0 years, male, white, stage:Stage IB, alive, 2289 days	0.0
TCGA-YU-AA61-01A	0 years, male, white, stage:Stage IS, alive, 864 days	0.0
TCGA-X3-A8G4-01A	0 years, male, white, stage:Stage IS, alive, 856 days	0.0
TCGA-ZM-AA0E-01A	0 years, male, white, stage:Stage IA, alive, 811 days	0.0
TCGA-2G-AAHT-01A	0 years, male, white, stage:Stage IS, alive, 542 days	0.0
TCGA-2G-AAGE-01A	0 years, male, white, stage:Stage IS, alive, 2478 days	0.0
TCGA-VF-A8AB-01A	0 years, male, black or african american, stage:Stage IA, alive, 760 days	0.0
TCGA-2G-AAGF-01A	0 years, male, white, stage:Stage IS, alive, 2734 days	0.0
TCGA-WZ-A7V3-01A	0 years, male, white, stage:Stage I, alive, 753 days	0.0
TCGA-2G-AAFL-01A	0 years, male, white, stage:Stage IB, alive, 750 days	0.0
TCGA-XE-A9SE-01A	0 years, male, white, stage:Stage IA, alive, 708 days	0.0
TCGA-ZM-AA0F-01A	0 years, male, white, stage:Stage IA, alive, 681 days	0.0
TCGA-XY-A8S2-01A	0 years, male, white, stage:Stage I, alive, 672 days	0.0
TCGA-2G-AAGN-01A	0 years, male, white, stage:Stage IIIB, alive, 3656 days	0.0
TCGA-YU-AA4L-01A	0 years, male, black or african american, stage:Stage IIIC, alive, 1573 days	0.0
TCGA-4K-AA1I-01A	0 years, male, white, stage:Stage IA, alive, 3 days	0.0
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TESTIS CANCER - Protein expressionⁱ A mouse-over function shows sample information and annotation data. Click on an image to view it in a full screen mode. Samples can be filtered based on level of antibody staining by selecting one or several of the following categories: high, medium, low and not detected. The assay and annotation is described here. Note that samples used for immunohistochemistry by the Human Protein Atlas do not correspond to samples in the TCGA dataset.

Antibody stainingⁱ Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells. Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.	Antibody HPA060604	Antibody CAB016072
Staining
High
Medium
Low
Not detected
Intensity
Strong
Moderate
Weak
Negative
Quantity
>75%
75%-25%
<25%
None
Location
Nuclear
Cytoplasmic/membranous
Cytoplasmic/membranous,nuclear
None
Seminoma, NOS
Carcinoma, Embryonal, NOS
Carcinoma, Embryonal, NOS Teratoma, malignant, NOS
Seminoma, NOS Carcinoma, Embryonal, NOS

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.

contact@proteinatlas.org