MIDBRAIN - Expression summary
Protein expressioni No data
RNA expressioni
Consensus:83.1 nTPM
HPA Brain:171.8 nTPM
GTEx:83.1 nTPM
FANTOM5:129.6 Scaled Tags Per Million
Pig:76.9 nTPM
Mouse:27.0 nTPM
Allen mouse:2.8 Expression energy
BRAIN - SINGLE CELL RNA EXPRESSION
Brain excitatory neuronsBrain inhibitory neuronsOther brain neuronsAstrocytesBergmann gliaOligodendrocyte progenitor cellsOligodendrocytesMicrogliaEpendymal cellsChoroid plexus epithelial cellsVascular endothelial cellsPericytesVascular smooth muscle cellsFibroblastsMonocytesMacrophagesT-cellsB-cellsNK-cells0100200300400500600nCPM

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi 171.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 143.2
2586 Male, age 75, left hemisphere 197.6
2019 Male, age 18, unknown 187.9
2828 Female, age 72, unknown 152.2
1830 Male, age 51, unknown 138.3
1833 Male, age 53, unknown 136.2
2411 Female, age 72, unknown 131.6
2666 Male, age 74, left hemisphere 127.4
1870 Female, age 42, unknown 124.4
1827 Male, age 72, unknown 118.3
2219 Male, age 76, both hemispheres 118.3
Dorsal raphe nucleus
nTPM: 99.8
2750 Male, age 76, both hemispheres 134.5
1828 Male, age 53, unknown 114.9
2016 Female, age 72, unknown 89.4
2047 Male, age 72, unknown 87.9
2298 Female, age 72, unknown 72.2
Inferior colliculus
nTPM: 115.5
1890 Male, age 53, unknown 151.1
2097 Female, age 72, unknown 113.3
1848 Female, age 42, unknown 103.0
2849 Male, age 72, unknown 94.7
Median raphe nucleus
nTPM: 90.4
2220 Male, age 76, midline 90.4
Periaquaductal grey, anterior
nTPM: 92.8
2502 Female, age 75, unknown 106.9
1795 Male, age 51, unknown 94.8
1947 Male, age 18, unknown 76.7
Periaquaductal grey, dorsal
nTPM: 74.7
2464 Female, age 72, unknown 99.5
1831 Male, age 72, unknown 87.9
1840 Male, age 53, unknown 61.1
2850 Male, age 76, both hemispheres 50.4
Periaquaductal grey, lateral
nTPM: 71.4
2053 Male, age 18, unknown 84.6
2272 Male, age 74, both hemispheres 81.8
2140 Male, age 76, both hemispheres 47.7
Pretectal area
nTPM: 114.5
1817 Female, age 42, unknown 158.5
2007 Male, age 72, unknown 144.9
1815 Male, age 53, unknown 143.5
1816 Male, age 51, unknown 139.0
1944 Female, age 72, unknown 133.0
2667 Female, age 75, unknown 118.8
2407 Male, age 75, both hemispheres 118.6
2316 Male, age 76, right hemisphere 82.2
2825 Male, age 18, unknown 80.2
2273 Male, age 74, both hemispheres 76.8
2224 Female, age 72, unknown 64.2
Red nucleus
nTPM: 171.8
2823 Male, age 76, right hemisphere 193.0
2588 Male, age 74, left hemisphere 192.5
2584 Male, age 75, left hemisphere 183.9
1904 Male, age 53, unknown 183.8
2785 Male, age 18, unknown 183.2
2227 Male, age 72, unknown 181.8
2769 Male, age 72, unknown 177.7
1865 Male, age 51, unknown 174.0
1821 Female, age 72, unknown 165.0
2503 Female, age 72, unknown 163.4
1954 Female, age 42, unknown 154.0
2725 Female, age 75, unknown 108.8
Substantia nigra
nTPM: 120.8
2583 Male, age 75, right hemisphere 168.9
2665 Male, age 74, both hemispheres 152.3
1889 Female, age 72, unknown 126.5
1851 Male, age 51, unknown 119.2
2590 Female, age 75, unknown 119.1
1916 Female, age 42, unknown 117.1
2699 Male, age 18, unknown 112.2
2409 Female, age 72, unknown 101.6
1941 Male, age 53, unknown 100.6
2241 Male, age 72, unknown 90.2
Superior colliculus
nTPM: 125.0
2668 Female, age 75, unknown 153.4
1995 Male, age 72, unknown 143.8
2664 Male, age 75, both hemispheres 143.6
2087 Female, age 72, unknown 132.9
1913 Female, age 42, unknown 132.3
2261 Male, age 18, unknown 122.3
2587 Male, age 74, left hemisphere 118.5
1839 Male, age 51, unknown 105.9
1796 Male, age 53, unknown 102.0
1895 Male, age 76, right hemisphere 95.3
Ventral tegmental area
nTPM: 115.7
2223 Female, age 72, unknown 180.9
2410 Female, age 72, unknown 128.5
2218 Male, age 76, both hemispheres 100.8
1942 Male, age 51, unknown 99.5
1915 Female, age 42, unknown 96.2
2021 Male, age 53, unknown 88.3

MIDBRAIN - GTEx RNA-seqi
Max subtype nTPMi 83.1
GTEx sample id Sample description nTPM
62.376.891.120.4125.1050100150200250300350400
Brain - Substantia nigra
Average nTPM: 83.1
Samples: 183

Max nTPM: 439.9
Min nTPM: 20.4
Std nTPM: 46.1
Median nTPM: 76.8
GTEX-WL46-0011-R2A-SM-3LK6O 50-59 years, male 439.9
GTEX-1MJK2-0011-R2b-SM-EXUS5 50-59 years, male 439.1
GTEX-1N5O9-0011-R2a-SM-G8LM1 60-69 years, male 210.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 199.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 186.6
GTEX-1IDJH-0011-R2a-SM-GPI9D 70-79 years, male 138.9
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 134.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 125.1
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 122.8
GTEX-1I19N-0011-R2b-SM-GPRYG 70-79 years, male 120.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 120.7
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MIDBRAIN - FANTOM5 CAGEi
Max subtype Scaled Tags Per Millioni 129.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 129.6
FF:10158-103A5 76 years, female 129.6

MIDBRAIN - Pig RNA-seqi
Max subtype nTPMi 76.9
Pig sample Sample description nTPM
54.360.065.744.075.9010203040506070
 		Substantia nigra
nTPM: 60.0
Samples: 4

Max nTPM: 75.9
Min nTPM: 44.0
Sample A Female 57.7
Sample B Female 44.0
Sample C Male 62.3
Sample D Male 75.9
57.763.883.051.367.80102030405060708090100110120
 		Midbrain
nTPM: 76.9
Samples: 4

Max nTPM: 128.8
Min nTPM: 51.3
Sample A Female 128.8
Sample B Female 51.3
Sample C Male 59.8
Sample D Male 67.8
41.342.444.540.246.6051015202530354045
 		Periaqueductal gray
nTPM: 43.1
Samples: 3

Max nTPM: 46.6
Min nTPM: 40.2
Sample B Female 46.6
Sample C Male 42.4
Sample D Male 40.2
56.363.364.362.765.505101520253035404550556065
 		Superior colliculi
nTPM: 57.3
Samples: 4

Max nTPM: 65.5
Min nTPM: 37.1
Sample A Female 63.9
Sample B Female 37.1
Sample C Male 62.7
Sample D Male 65.5

MIDBRAIN - Mouse RNA-seqi
Max subtype nTPMi 27.0
Mouse sample Sample description nTPM
26.427.328.025.628.00246810121416182022242628
 		Midbrain
nTPM: 27.1
Samples: 4

Max nTPM: 28.0
Min nTPM: 25.6
Sample A Male 28.0
Sample B Male 25.6
Sample C Female 28.0
Sample D Female 26.6

MIDBRAIN - Allen Mouse ISHi
Max subtype Expression energyi 2.8
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 2.8
1735 Antisense, RP_040507_02_H04, Mouse strain C57BL/6J (56 days, male) 4.1
77371857 Antisense, RP_070129_01_B10, Mouse strain C57BL/6J (56 days, male) 1.4
1734 Antisense, RP_040507_02_H04, Mouse strain C57BL/6J (56 days, male) 0.2

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