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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Medium
Hepatocytes:
Low
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
112.9
nTPM
HPA:
36.3
nTPM
GTEx:
112.9
nTPM
FANTOM5:
219.0
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA003245
Cholangiocytes
Medium
Hepatocytes
Low
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
36.3
Female, age 60
Liver sample 21 nTPM: 28.3
Male, age 54
Liver sample 23 nTPM: 28.9
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 23.8
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 49
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 17.5
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 29.5
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 64.2
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 34
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 64.3
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 23.9
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
112.9
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 112.9
Samples: 226
Max nTPM: 330.3
Min nTPM: 13.8
Std nTPM: 61.8
Median nTPM: 100.5
GTEX-14PJO-1726-SM-68719
60-69 years, male
330.3
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
317.0
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
311.3
GTEX-13113-1326-SM-5GCOI
60-69 years, female
307.6
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
273.2
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
243.0
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
238.8
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
238.6
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
238.0
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
237.2
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
226.8
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
225.6
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
222.8
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
222.6
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
222.1
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
217.9
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
210.5
GTEX-14XAO-0226-SM-68728
60-69 years, female
210.2
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
210.1
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
204.2
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
200.5
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
199.7
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
197.4
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
197.1
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
197.1
GTEX-12696-0826-SM-5EGGE
60-69 years, male
194.7
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
194.6
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
192.4
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
192.0
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
191.2
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
188.0
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
187.2
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
183.0
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
182.7
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
179.1
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
179.0
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
176.0
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
170.6
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
169.4
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
168.4
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
166.3
GTEX-REY6-1226-SM-48FDR
60-69 years, male
165.1
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
163.0
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
162.6
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
161.8
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
160.8
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
160.8
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
158.9
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
158.6
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
158.5
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
156.6
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
155.0
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
154.2
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
154.2
GTEX-17F96-1226-SM-79OK2
70-79 years, male
153.4
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
152.7
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
152.0
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
150.8
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
150.2
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
148.1
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
147.8
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
146.4
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
145.8
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
144.2
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
143.5
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
143.0
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
141.2
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
140.8
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
140.3
GTEX-RU72-1426-SM-46MUF
50-59 years, female
139.9
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
138.6
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
136.9
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
132.6
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
132.0
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
131.4
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
130.4
GTEX-S32W-1926-SM-4AD63
50-59 years, female
129.9
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
129.8
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
128.8
GTEX-QEL4-1226-SM-447A4
50-59 years, male
128.5
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
127.6
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
124.1
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
124.0
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
122.7
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
122.4
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
122.2
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
121.8
GTEX-14PHX-0526-SM-664NW
50-59 years, male
121.6
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
119.3
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
118.3
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
117.6
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
117.5
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
117.3
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
116.9
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
116.7
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
116.1
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
115.9
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
114.4
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
113.9
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
111.7
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
110.3
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
109.5
GTEX-P78B-1326-SM-3P611
40-49 years, female
109.4
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
108.9
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
108.5
GTEX-O5YV-0726-SM-EV798
60-69 years, female
108.3
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
107.6
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
104.4
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
102.9
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
102.9
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
101.6
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
101.2
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
101.1
GTEX-18A66-2026-SM-7189C
60-69 years, male
99.8
GTEX-X261-1726-SM-4PQYT
50-59 years, male
98.2
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
97.3
GTEX-17HHE-0126-SM-79398
50-59 years, male
96.6
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
94.8
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
94.1
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
94.1
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
93.7
GTEX-11ZUS-2526-SM-59872
30-39 years, male
93.2
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
90.9
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
90.5
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
89.1
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
88.5
GTEX-18465-1626-SM-7LG6N
50-59 years, male
87.8
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
86.9
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
85.2
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
85.0
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
84.9
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
84.6
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
84.6
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
83.8
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
83.7
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
83.7
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
83.5
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
82.6
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
81.7
GTEX-1B933-1226-SM-731DW
50-59 years, female
81.6
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
79.6
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
79.1
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
78.4
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
77.1
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
75.9
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
75.6
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
74.4
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
74.3
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
73.7
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
73.5
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
73.0
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
72.8
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
72.6
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
72.0
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
71.9
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
71.7
GTEX-R53T-0326-SM-48FEC
50-59 years, female
71.6
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
71.0
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
70.7
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
70.2
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
69.0
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
69.0
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
68.4
GTEX-RN64-1826-SM-48FDV
50-59 years, male
67.5
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
67.0
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
66.7
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
66.4
GTEX-1B932-1426-SM-793AN
40-49 years, female
66.3
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
66.0
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
66.0
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
65.9
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
65.8
GTEX-S33H-1626-SM-4AD68
30-39 years, male
65.2
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
64.6
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
63.8
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
63.6
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
63.3
GTEX-14E7W-1526-SM-6871X
70-79 years, male
62.8
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
62.5
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
62.3
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
62.2
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
58.7
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
58.5
GTEX-13112-1426-SM-5EGH8
50-59 years, male
58.5
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
58.1
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
57.4
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
57.3
GTEX-1399T-0826-SM-5IFES
60-69 years, male
57.1
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
57.0
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
56.6
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
54.3
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
54.0
GTEX-Q734-0326-SM-48U15
40-49 years, female
53.9
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
53.8
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
53.1
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
52.4
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
52.2
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
51.9
GTEX-11GSP-0626-SM-5986T
60-69 years, female
50.6
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
50.6
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
50.1
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
49.0
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
48.9
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
46.2
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
46.0
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
43.5
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
43.5
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
43.3
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
41.5
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
40.9
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
37.4
GTEX-18A7A-1526-SM-72D69
50-59 years, female
37.2
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
37.1
GTEX-144GL-1426-SM-79OMA
50-59 years, male
36.5
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
36.1
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
35.3
GTEX-YECK-1926-SM-4W21H
60-69 years, male
33.5
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
30.4
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
30.2
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
29.0
GTEX-QESD-2026-SM-447BI
20-29 years, male
27.5
GTEX-14JG1-1626-SM-664NH
40-49 years, male
26.6
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
21.6
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
20.7
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
13.9
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
13.8
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
