Expression of CXCL10 in glioma - The Human Protein Atlas

GLIOBLASTOMA MULTIFORME (TCGA) - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

CXCL10 is not prognostic in Glioblastoma Multiforme (TCGA)

Stage:

Survival analysis

Current cut offⁱ :

Best expression cut offⁱ : 12.45

Median expressionⁱ : N/A

Median follow up timeⁱ : N/A

P scoreⁱ N/A

3-year survival highⁱ N/A

3-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average TPM

27.9

Number of samples

141

Samples

Sample	Description	TPM
TCGA-28-5218-01A	0 years, male, white, stage:'--, dead, 157 days	286.6
TCGA-06-0130-01A	0 years, male, white, stage:'--, dead, 394 days	201.6
TCGA-28-2513-01A	0 years, female, white, stage:'--, alive, 222 days	137.1
TCGA-28-5204-01A	0 years, male, white, stage:'--, dead, 454 days	130.0
TCGA-12-5295-01A	0 years, female, white, stage:'--, dead, 454 days	123.4
TCGA-12-3653-01A	0 years, female, white, stage:'--, dead, 442 days	120.6
TCGA-02-2486-01A	0 years, male, white, stage:'--, dead, 618 days	118.7
TCGA-06-2563-01A	0 years, female, white, stage:'--, alive, 932 days	111.5
TCGA-16-0846-01A	0 years, male, white, stage:'--, dead, 119 days	105.4
TCGA-32-2638-01A	0 years, male, white, stage:'--, dead, 766 days	104.3
TCGA-12-5299-01A	0 years, female, white, stage:'--, dead, 98 days	101.1
TCGA-06-0750-01A	0 years, male, white, stage:'--, dead, 28 days	91.2
TCGA-41-2572-01A	0 years, male, white, stage:'--, dead, 406 days	89.5
TCGA-02-2485-01A	0 years, male, black or african american, stage:'--, alive, 470 days	88.5
TCGA-32-4213-01A	0 years, female, white, stage:'--, alive, 604 days	79.8
TCGA-27-1831-01A	0 years, male, white, stage:'--, dead, 505 days	72.7
TCGA-32-5222-01A	0 years, male, white, stage:'--, dead, 585 days	72.4
TCGA-14-0817-01A	0 years, female, white, stage:'--, dead, 164 days	72.1
TCGA-06-0219-01A	0 years, male, white, stage:'--, dead, 22 days	71.9
TCGA-27-1834-01A	0 years, male, white, stage:'--, dead, 1233 days	59.8
TCGA-06-2567-01A	0 years, male, white, stage:'--, dead, 133 days	54.3
TCGA-06-0139-01A	0 years, male, white, stage:'--, dead, 362 days	52.2
TCGA-06-2557-01A	0 years, male, black or african american, stage:'--, dead, 33 days	49.3
TCGA-27-2526-01A	0 years, female, white, stage:'--, dead, 87 days	46.4
TCGA-28-5209-01A	0 years, female, white, stage:'--, alive, 442 days	40.6
TCGA-32-2632-01A	0 years, male, white, stage:'--, dead, 269 days	40.6
TCGA-32-2615-01A	0 years, male, white, stage:'--, dead, 485 days	35.7
TCGA-27-1835-01A	0 years, female, white, stage:'--, dead, 648 days	35.4
TCGA-28-5220-01A	0 years, male, white, stage:'--, dead, 388 days	33.8
TCGA-06-0187-01A	0 years, male, white, stage:'--, dead, 828 days	33.5
TCGA-19-4065-01A	0 years, male, white, stage:'--, alive, 214 days	31.0
TCGA-06-5414-01A	0 years, male, white, stage:'--, alive, 273 days	29.5
TCGA-12-3652-01A	0 years, male, white, stage:'--, dead, 1062 days	29.2
TCGA-06-0238-01A	0 years, male, white, stage:'--, dead, 405 days	28.9
TCGA-06-0878-01A	0 years, male, white, stage:'--, alive, 218 days	28.6
TCGA-06-0168-01A	0 years, female, white, stage:'--, dead, 598 days	28.3
TCGA-27-2519-01A	0 years, male, white, stage:'--, dead, 550 days	27.0
TCGA-27-1837-01A	0 years, male, white, stage:'--, dead, 427 days	26.5
TCGA-06-5408-01A	0 years, female, white, stage:'--, dead, 357 days	26.4
TCGA-14-0787-01A	0 years, male, asian, stage:'--, dead, 68 days	26.2
TCGA-26-5139-01A	0 years, female, white, stage:'--, alive, 48 days	26.2
TCGA-06-0645-01A	0 years, female, white, stage:'--, dead, 175 days	25.9
TCGA-28-2514-01A	0 years, male, asian, stage:'--, alive, 160 days	24.4
TCGA-32-2616-01A	0 years, female, white, stage:'--, dead, 224 days	24.2
TCGA-06-2565-01A	0 years, male, asian, stage:'--, dead, 506 days	24.2
TCGA-06-0129-01A	0 years, male, asian, stage:'--, dead, 1024 days	23.7
TCGA-06-5413-01A	0 years, male, white, stage:'--, alive, 268 days	22.9
TCGA-28-1753-01A	0 years, male, white, stage:'--, alive, 37 days	22.1
TCGA-06-5859-01A	0 years, male, white, stage:'--, alive, 139 days	21.5
TCGA-06-0138-01A	0 years, male, white, stage:'--, dead, 737 days	21.3
TCGA-06-0646-01A	0 years, male, white, stage:'--, dead, 175 days	21.2
TCGA-06-2561-01A	0 years, female, white, stage:'--, dead, 537 days	20.1
TCGA-32-1980-01A	0 years, male, white, stage:'--, dead, 36 days	18.7
TCGA-12-0616-01A	0 years, female, white, stage:'--, dead, 448 days	18.1
TCGA-32-1982-01A	0 years, female, white, stage:'--, dead, 142 days	17.6
TCGA-06-5412-01A	0 years, female, white, stage:'--, dead, 138 days	16.3
TCGA-06-0132-01A	0 years, male, white, stage:'--, dead, 771 days	16.2
TCGA-06-0156-01A	0 years, male, white, stage:'--, dead, 178 days	16.2
TCGA-14-1823-01A	0 years, female, white, stage:'--, dead, 543 days	16.1
TCGA-14-2554-01A	0 years, female, white, stage:'--, dead, 532 days	15.9
TCGA-26-5135-01A	0 years, female, white, stage:'--, dead, 270 days	15.5
TCGA-14-1829-01A	0 years, male, black or african american, stage:'--, alive, 218 days	15.4
TCGA-02-0055-01A	0 years, female, white, stage:'--, dead, 76 days	15.4
TCGA-28-5208-01A	0 years, male, white, stage:'--, dead, 544 days	14.0
TCGA-19-2619-01A	0 years, female, black or african american, stage:'--, alive, 294 days	13.8
TCGA-06-0211-01A	0 years, male, white, stage:'--, dead, 360 days	13.2
TCGA-19-1390-01A	0 years, female, white, stage:'--, dead, 772 days	13.1
TCGA-06-0141-01A	0 years, male, white, stage:'--, dead, 313 days	13.0
TCGA-32-1970-01A	0 years, male, white, stage:'--, dead, 468 days	12.9
TCGA-06-5856-01A	0 years, male, white, stage:'--, dead, 114 days	12.8
TCGA-27-2524-01A	0 years, male, white, stage:'--, dead, 231 days	12.6
TCGA-06-0745-01A	0 years, male, white, stage:'--, dead, 239 days	12.6
TCGA-12-0619-01A	0 years, male, white, stage:'--, dead, 1062 days	12.3
TCGA-06-2559-01A	0 years, male, white, stage:'--, dead, 150 days	11.6
TCGA-06-5858-01A	0 years, female, white, stage:'--, alive, 187 days	11.4
TCGA-06-0178-01A	0 years, male, white, stage:'--, dead, 2681 days	11.4
TCGA-06-0882-01A	0 years, male, white, stage:'--, dead, 632 days	11.3
TCGA-06-0158-01A	0 years, male, white, stage:'--, dead, 329 days	11.2
TCGA-06-2570-01A	0 years, female, white, stage:'--, alive, 958 days	11.2
TCGA-19-2629-01A	0 years, male, white, stage:'--, dead, 737 days	10.7
TCGA-76-4929-01A	0 years, female, white, stage:'--, dead, 111 days	10.6
TCGA-06-0743-01A	0 years, male, white, stage:'--, dead, 803 days	10.5
TCGA-28-5215-01A	0 years, female, white, stage:'--, dead, 335 days	10.4
TCGA-02-0047-01A	0 years, male, white, stage:'--, dead, 448 days	10.3
TCGA-06-0125-01A	0 years, female, white, stage:'--, dead, 1448 days	10.2
TCGA-27-1832-01A	0 years, female, white, stage:'--, dead, 300 days	9.3
TCGA-32-2634-01A	0 years, male, white, stage:'--, alive, 693 days	8.5
TCGA-14-1034-01A	0 years, female, stage:'--, dead, 485 days	8.3
TCGA-06-5418-01A	0 years, female, white, stage:'--, dead, 83 days	8.3
TCGA-06-0157-01A	0 years, female, white, stage:'--, dead, 97 days	8.1
TCGA-06-0744-01A	0 years, male, white, stage:'--, dead, 1426 days	7.9
TCGA-26-5132-01A	0 years, male, white, stage:'--, alive, 286 days	7.9
TCGA-06-0644-01A	0 years, male, black or african american, stage:'--, dead, 384 days	7.8
TCGA-06-1804-01A	0 years, female, white, stage:'--, dead, 414 days	7.7
TCGA-76-4927-01A	0 years, male, white, stage:'--, dead, 535 days	7.5
TCGA-14-0871-01A	0 years, female, white, stage:'--, dead, 880 days	7.4
TCGA-06-2564-01A	0 years, male, white, stage:'--, alive, 181 days	6.5
TCGA-41-4097-01A	0 years, female, white, stage:'--, dead, 6 days	6.4
TCGA-26-5134-01A	0 years, male, white, stage:'--, alive, 167 days	6.2
TCGA-28-5207-01A	0 years, male, white, stage:'--, dead, 343 days	6.2
TCGA-27-1830-01A	0 years, male, white, stage:'--, dead, 154 days	6.1
TCGA-15-0742-01A	0 years, male, white, stage:'--, dead, 419 days	6.1
TCGA-06-0749-01A	0 years, male, black or african american, stage:'--, dead, 82 days	6.0
TCGA-06-5416-01A	0 years, female, white, stage:'--, alive, 204 days	5.9
TCGA-06-5411-01A	0 years, male, white, stage:'--, dead, 254 days	5.9
TCGA-27-2523-01A	0 years, male, white, stage:'--, dead, 489 days	5.7
TCGA-06-0190-01A	0 years, male, white, stage:'--, dead, 317 days	5.7
TCGA-19-2624-01A	0 years, male, white, stage:'--, dead, 5 days	5.7
TCGA-19-5960-01A	0 years, male, white, stage:'--, dead, 455 days	5.5
TCGA-76-4932-01A	0 years, female, white, stage:'--, dead, 1458 days	5.4
TCGA-06-2562-01A	0 years, male, white, stage:'--, dead, 382 days	5.4
TCGA-76-4925-01A	0 years, male, white, stage:'--, dead, 146 days	5.4
TCGA-06-5410-01A	0 years, female, white, stage:'--, dead, 108 days	5.4
TCGA-06-0184-01A	0 years, male, white, stage:'--, dead, 2126 days	5.3
TCGA-02-2483-01A	0 years, male, asian, stage:'--, alive, 466 days	4.7
TCGA-28-5216-01A	0 years, male, white, stage:'--, alive, 415 days	4.7
TCGA-19-2625-01A	0 years, female, white, stage:'--, dead, 124 days	4.5
TCGA-15-1444-01A	0 years, male, white, stage:'--, dead, 1537 days	4.3
TCGA-06-0747-01A	0 years, male, white, stage:'--, dead, 82 days	4.2
TCGA-14-0789-01A	0 years, male, white, stage:'--, dead, 342 days	4.2
TCGA-14-1825-01A	0 years, male, white, stage:'--, dead, 232 days	4.1
TCGA-12-0618-01A	0 years, male, white, stage:'--, dead, 395 days	4.1
TCGA-12-3650-01A	0 years, male, white, stage:'--, dead, 333 days	4.1
TCGA-06-0686-01A	0 years, male, white, stage:'--, dead, 432 days	3.8
TCGA-12-0821-01A	0 years, male, white, stage:'--, dead, 323 days	3.7
TCGA-27-2528-01A	0 years, male, white, stage:'--, dead, 480 days	3.4
TCGA-26-5133-01A	0 years, male, white, stage:'--, alive, 452 days	3.2
TCGA-41-3915-01A	0 years, male, white, stage:'--, dead, 360 days	3.2
TCGA-28-2509-01A	0 years, female, white, stage:'--, alive, 145 days	3.1
TCGA-06-5417-01A	0 years, female, white, stage:'--, alive, 155 days	3.0
TCGA-06-0210-01A	0 years, female, white, stage:'--, dead, 225 days	3.0
TCGA-76-4931-01A	0 years, female, white, stage:'--, dead, 279 days	2.9
TCGA-06-0174-01A	0 years, male, white, stage:'--, dead, 98 days	2.8
TCGA-06-2558-01A	0 years, female, white, stage:'--, dead, 380 days	2.7
TCGA-41-5651-01A	0 years, female, black or african american, stage:'--, dead, 460 days	2.6
TCGA-19-2620-01A	0 years, male, white, stage:'--, dead, 148 days	2.5
TCGA-08-0386-01A	0 years, male, white, stage:'--, dead, 548 days	1.4
TCGA-06-2569-01A	0 years, female, black or african american, stage:'--, alive, 13 days	1.1
TCGA-41-2571-01A	0 years, male, white, stage:'--, dead, 26 days	1.0
TCGA-27-2521-01A	0 years, male, white, stage:'--, dead, 510 days	0.9
TCGA-26-1442-01A	0 years, male, white, stage:'--, alive, 953 days	0.9
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GLIOBLASTOMA MULTIFORME (VALIDATION) - Interactive survival scatter plotⁱ

& Survival analysisⁱ

CXCL10 is not prognostic in Glioblastoma Multiforme (validation)

Stage:

Survival analysis

Current cut offⁱ :

Best expression cut offⁱ : 2.22

Median expressionⁱ : N/A

Median follow up timeⁱ : N/A

P scoreⁱ N/A

3-year survival highⁱ N/A

3-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average TPM

32.9

Number of samples

Samples

Sample	Description	TPM
AK178	N, NA, stage:NA, dead, 240 days	403.9
AK072	N, NA, stage:NA, dead, 150 days	394.4
AK185	N, NA, stage:NA, alive, 330 days	384.0
AK123	N, NA, stage:NA, dead, 180 days	121.7
AK100	N, NA, stage:NA, alive, 960 days	114.4
AK205	N, NA, stage:NA, dead, 120 days	82.0
AK003	N, NA, stage:NA, dead, 600 days	37.0
AK236	N, NA, stage:NA, dead, 360 days	32.4
AK103	N, NA, stage:NA, alive, 1320 days	23.4
AK226	N, NA, stage:NA, dead, 360 days	18.0
AK183	N, NA, stage:NA, alive, 360 days	17.2
AK099	N, NA, stage:NA, dead, 420 days	17.1
AK098	N, NA, stage:NA, dead, 660 days	17.0
AK153	N, NA, stage:NA, dead, 240 days	16.7
AK216	N, NA, stage:NA, dead, 360 days	15.9
AK227	N, NA, stage:NA, alive, 300 days	15.2
AK085	N, NA, stage:NA, alive, 660 days	15.0
AK195	N, NA, stage:NA, dead, 390 days	13.6
AK081	N, NA, stage:NA, dead, 180 days	13.1
AK068	N, NA, stage:NA, alive, 360 days	12.0
AK188	N, NA, stage:NA, alive, 420 days	10.4
AK005	N, NA, stage:NA, dead, 240 days	9.9
AK167	N, NA, stage:NA, dead, 180 days	9.1
AK053	N, NA, stage:NA, dead, 300 days	8.8
AK071	N, NA, stage:NA, dead, 540 days	8.2
AK158	N, NA, stage:NA, dead, 360 days	7.2
AK133	N, NA, stage:NA, dead, 360 days	6.8
AK199	N, NA, stage:NA, alive, 1860 days	6.6
AK124	N, NA, stage:NA, alive, 1920 days	5.8
AK231	N, NA, stage:NA, dead, 240 days	5.6
AK089	N, NA, stage:NA, dead, 330 days	5.4
AK030	N, NA, stage:NA, dead, 120 days	5.3
AK079	N, NA, stage:NA, dead, 210 days	5.2
AK051	N, NA, stage:NA, dead, 360 days	4.6
AK218	N, NA, stage:NA, dead, 180 days	4.3
AK173	N, NA, stage:NA, dead, 180 days	4.2
AK041	N, NA, stage:NA, alive, 810 days	4.2
AK091	N, NA, stage:NA, dead, 210 days	3.9
AK049	N, NA, stage:NA, dead, 180 days	3.7
AK142	N, NA, stage:NA, alive, 90 days	3.1
AK149	N, NA, stage:NA, dead, 420 days	2.7
AK002	N, NA, stage:NA, dead, 570 days	2.3
AK076	N, NA, stage:NA, alive, 660 days	2.2
AK139	N, NA, stage:NA, dead, 270 days	2.1
AK066	N, NA, stage:NA, alive, 960 days	2.1
AK055	N, NA, stage:NA, dead, 240 days	1.6
AK074	N, NA, stage:NA, alive, 300 days	1.4
AK134	N, NA, stage:NA, dead, 360 days	1.2
AK088	N, NA, stage:NA, dead, 360 days	1.0
AK035	N, NA, stage:NA, dead, 210 days	1.0
AK213	N, NA, stage:NA, alive, 2010 days	0.9
AK156	N, NA, stage:NA, dead, 330 days	0.7
AK165	N, NA, stage:NA, alive, 360 days	0.7
AK117	N, NA, stage:NA, dead, 210 days	0.6
AK015	N, NA, stage:NA, alive, 720 days	0.6
AK006	N, NA, stage:NA, dead, 360 days	0.6
AK043	N, NA, stage:NA, alive, 660 days	0.6
AK102	N, NA, stage:NA, alive, 1740 days	0.3
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GLIOBLASTOMA MULTIFORME - Protein relative expression (CPTAC)

Number of samples

110

Samples

Sample ID	Sample type	nRPX
CPT0206330003	Tumor	N/A
CPT0186100003	Tumor	N/A
CPT0123530003	Tumor	N/A
CPT0201710003	Tumor	N/A
CPT0216920008	Tumor	N/A
CPT0218890004	Tumor	N/A
CPT0224390004	Tumor	N/A
CPT0204390003	Normal	N/A
CPT0093590003	Tumor	N/A
CPT0167750004	Tumor	N/A
CPT0204400003	Normal	N/A
CPT0079790003	Tumor	N/A
CPT0218690004	Tumor	N/A
CPT0204370003	Normal	N/A
CPT0161730003	Tumor	N/A
CPT0168720003	Tumor	N/A
CPT0206880003	Tumor	N/A
CPT0189650004	Tumor	N/A
CPT0204350003	Normal	N/A
CPT0168380003	Tumor	N/A
CPT0205890003	Tumor	N/A
CPT0217880003	Tumor	N/A
CPT0206560003	Tumor	N/A
CPT0087680003	Tumor	N/A
CPT0206000004	Tumor	N/A
CPT0218670003	Tumor	N/A
CPT0204340003	Normal	N/A
CPT0189850004	Tumor	N/A
CPT0224330003	Tumor	N/A
CPT0218330004	Tumor	N/A
CPT0167640003	Tumor	N/A
CPT0002410011	Tumor	N/A
CPT0093450003	Tumor	N/A
CPT0206110003	Tumor	N/A
CPT0217430008	Tumor	N/A
CPT0217000004	Tumor	N/A
CPT0196850003	Tumor	N/A
CPT0189250003	Tumor	N/A
CPT0189570004	Tumor	N/A
CPT0162020003	Tumor	N/A
CPT0167530003	Tumor	N/A
CPT0207030003	Tumor	N/A
CPT0127420003	Tumor	N/A
CPT0205670004	Tumor	N/A
CPT0208980003	Tumor	N/A
CPT0206780003	Tumor	N/A
CPT0182500003	Tumor	N/A
CPT0217710008	Tumor	N/A
CPT0168830003	Tumor	N/A
CPT0182550003	Tumor	N/A
CPT0189460003	Tumor	N/A
CPT0167860004	Tumor	N/A
CPT0125220003	Tumor	N/A
CPT0171580008	Tumor	N/A
CPT0087730003	Tumor	N/A
CPT0104330003	Tumor	N/A
CPT0168590003	Tumor	N/A
CPT0205450004	Tumor	N/A
CPT0219080004	Tumor	N/A
CPT0087570003	Tumor	N/A
CPT0162140003	Tumor	N/A
CPT0175060003	Tumor	N/A
CPT0205780003	Tumor	N/A
CPT0218960004	Tumor	N/A
CPT0064650003	Tumor	N/A
CPT0125570003	Tumor	N/A
CPT0190360004	Tumor	N/A
CPT0206670004	Tumor	N/A
CPT0204380003	Normal	N/A
CPT0092440003	Tumor	N/A
CPT0162100003	Tumor	N/A
CPT0221180003	Tumor	N/A
CPT0225760003	Tumor	N/A
CPT0093510003	Tumor	N/A
CPT0190240004	Tumor	N/A
CPT0228220003	Tumor	N/A
CPT0204410003	Normal	N/A
CPT0224540004	Tumor	N/A
CPT0209440003	Tumor	N/A
CPT0089150003	Tumor	N/A
CPT0204360003	Normal	N/A
CPT0168080003	Tumor	N/A
CPT0078580003	Tumor	N/A
CPT0127480003	Tumor	N/A
CPT0204420003	Normal	N/A
CPT0218830004	Tumor	N/A
CPT0225730003	Tumor	N/A
CPT0093360003	Tumor	N/A
CPT0168270003	Tumor	N/A
CPT0206450003	Tumor	N/A
CPT0207090003	Tumor	N/A
CPT0104220003	Tumor	N/A
CPT0224600003	Tumor	N/A
CPT0087950003	Tumor	N/A
CPT0204330003	Normal	N/A
CPT0199770003	Tumor	N/A
CPT0205570003	Tumor	N/A
CPT0093550003	Tumor	N/A
CPT0167970003	Tumor	N/A
CPT0182580003	Tumor	N/A
CPT0168480003	Tumor	N/A
CPT0206230003	Tumor	N/A
CPT0189750004	Tumor	N/A
CPT0217100003	Tumor	N/A
CPT0064890003	Tumor	N/A
CPT0217190003	Tumor	N/A
CPT0218770003	Tumor	N/A
CPT0125510003	Tumor	N/A
CPT0217060003	Tumor	N/A
CPT0071100003	Tumor	N/A
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GLIOMA - Protein expressionⁱ

Pending cancer tissue analysis