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Cytoplasmic immunoreactivity in virtually all neurons in the brain. The staining intensity is usually high. Especially strong in the neocortex, hypothalamus, mitral cells in the olfactory bulb, Purkinje cells in the cerebellum and multiple medullar/pontine nuclei (like motor trigeminal nucleus or lateral paragigantocellular nucleus).
Positive cells and structuresi
Manually selected location of the protein positivity, observed by immunofluorescence staining in mouse brain.
Soma and dendrite in neurons. Choroid plexus and circumventricular organs of ependymal cells.
Distinct positivity in paraventricular hypothalamic nucleus and periventricular hypothalamic nucleus (hypothalamus, interbrain)