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Broad and general moderate-strong intensity immunostaining of microglial cells throughout the entire forebrain. This stainig is less intense (weak) in the upper (I-III) layers of neocortex and in the thalamus.
In the brainstem, the strong microglial immunostaining is more restricted to certain (gray-matter reach) regions, like the periaqueductal gray matter, substantia nigra or the dorsal (periventricular) region of the medulla; however, with less intensity, i9t occurs in all brainstem regions. In the cerebellum, only weak microglial staining is noticed.
In addition, strong somatic (cytoplasmic+nuclear) immunostaining of subsets of neurons is noticed in the lateral septum and in the (anterior and tuberal) hypothalamus.
Positive cells and structuresi
Manually selected location of the protein positivity, observed by immunofluorescence staining in mouse brain.
The Human Protein Atlas project is funded
