MIDBRAIN - Expression summary
Protein expressioni No data
RNA expressioni
Consensus:22.6 nTPM
HPA Brain:105.1 nTPM
GTEx:22.6 nTPM
FANTOM5:177.6 Scaled Tags Per Million
Pig:160.4 nTPM
Mouse:137.9 nTPM
Allen mouse:1.9 Expression energy
BRAIN - SINGLE CELL RNA EXPRESSION
Brain excitatory neuronsBrain inhibitory neuronsOther brain neuronsAstrocytesBergmann gliaOligodendrocyte progenitor cellsOligodendrocytesMicrogliaEpendymal cellsChoroid plexus epithelial cellsVascular endothelial cellsPericytesVascular smooth muscle cellsFibroblastsMonocytesMacrophagesT-cellsB-cellsNK-cells020406080100nCPM

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi 105.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 90.8
2019 Male, age 18, unknown 106.2
1827 Male, age 72, unknown 96.6
2828 Female, age 72, unknown 95.6
1833 Male, age 53, unknown 94.0
1870 Female, age 42, unknown 93.6
2411 Female, age 72, unknown 91.9
1830 Male, age 51, unknown 88.9
2586 Male, age 75, left hemisphere 82.0
2219 Male, age 76, both hemispheres 80.0
2666 Male, age 74, left hemisphere 79.4
Dorsal raphe nucleus
nTPM: 97.7
2298 Female, age 72, unknown 112.0
2016 Female, age 72, unknown 96.7
1828 Male, age 53, unknown 93.8
2750 Male, age 76, both hemispheres 93.6
2047 Male, age 72, unknown 92.2
Inferior colliculus
nTPM: 96.6
2097 Female, age 72, unknown 99.3
1848 Female, age 42, unknown 97.6
2849 Male, age 72, unknown 95.7
1890 Male, age 53, unknown 93.6
Median raphe nucleus
nTPM: 98.9
2220 Male, age 76, midline 98.9
Periaquaductal grey, anterior
nTPM: 91.5
1795 Male, age 51, unknown 94.2
1947 Male, age 18, unknown 92.0
2502 Female, age 75, unknown 88.4
Periaquaductal grey, dorsal
nTPM: 98.7
2850 Male, age 76, both hemispheres 111.3
1840 Male, age 53, unknown 100.2
1831 Male, age 72, unknown 93.7
2464 Female, age 72, unknown 89.5
Periaquaductal grey, lateral
nTPM: 103.1
2272 Male, age 74, both hemispheres 116.3
2140 Male, age 76, both hemispheres 100.2
2053 Male, age 18, unknown 92.8
Pretectal area
nTPM: 105.1
1817 Female, age 42, unknown 122.5
1816 Male, age 51, unknown 115.2
2273 Male, age 74, both hemispheres 115.0
2007 Male, age 72, unknown 113.9
1815 Male, age 53, unknown 110.5
1944 Female, age 72, unknown 109.3
2667 Female, age 75, unknown 101.1
2224 Female, age 72, unknown 100.0
2407 Male, age 75, both hemispheres 98.1
2825 Male, age 18, unknown 88.6
2316 Male, age 76, right hemisphere 82.1
Red nucleus
nTPM: 94.5
2725 Female, age 75, unknown 103.7
2503 Female, age 72, unknown 102.9
1865 Male, age 51, unknown 100.9
2785 Male, age 18, unknown 100.5
1821 Female, age 72, unknown 99.0
2823 Male, age 76, right hemisphere 98.4
1954 Female, age 42, unknown 96.0
1904 Male, age 53, unknown 94.8
2227 Male, age 72, unknown 91.5
2769 Male, age 72, unknown 91.5
2588 Male, age 74, left hemisphere 78.9
2584 Male, age 75, left hemisphere 76.1
Substantia nigra
nTPM: 94.7
2409 Female, age 72, unknown 106.4
1889 Female, age 72, unknown 105.5
2590 Female, age 75, unknown 97.5
1916 Female, age 42, unknown 95.4
1851 Male, age 51, unknown 92.8
1941 Male, age 53, unknown 92.4
2665 Male, age 74, both hemispheres 91.6
2583 Male, age 75, right hemisphere 90.5
2699 Male, age 18, unknown 87.6
2241 Male, age 72, unknown 87.0
Superior colliculus
nTPM: 96.1
2261 Male, age 18, unknown 106.7
1995 Male, age 72, unknown 105.6
2087 Female, age 72, unknown 105.1
2587 Male, age 74, left hemisphere 97.7
1913 Female, age 42, unknown 97.0
1796 Male, age 53, unknown 96.8
1895 Male, age 76, right hemisphere 91.8
2668 Female, age 75, unknown 90.0
1839 Male, age 51, unknown 87.4
2664 Male, age 75, both hemispheres 82.3
Ventral tegmental area
nTPM: 92.5
2410 Female, age 72, unknown 99.7
2223 Female, age 72, unknown 97.5
2218 Male, age 76, both hemispheres 96.3
2021 Male, age 53, unknown 88.5
1915 Female, age 42, unknown 87.0
1942 Male, age 51, unknown 86.1

MIDBRAIN - GTEx RNA-seqi
Max subtype nTPMi 22.6
GTEx sample id Sample description nTPM
19.422.325.111.532.105101520253035
Brain - Substantia nigra
Average nTPM: 22.6
Samples: 183

Max nTPM: 36.5
Min nTPM: 11.5
Std nTPM: 4.6
Median nTPM: 22.3
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 36.5
GTEX-1192X-0011-R2b-SM-GI4VV 50-59 years, male 36.0
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 35.3
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 34.8
GTEX-WVLH-0011-R2A-SM-3MJFJ 50-59 years, male 34.3
GTEX-1MJK2-0011-R2b-SM-EXUS5 50-59 years, male 34.2
GTEX-ZYY3-0011-R2a-SM-GNTB2 60-69 years, female 32.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 31.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 31.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 31.0
GTEX-1JN1M-0011-R2b-SM-G9EPE 60-69 years, female 30.7
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MIDBRAIN - FANTOM5 CAGEi
Max subtype Scaled Tags Per Millioni 177.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 177.6
FF:10158-103A5 76 years, female 177.6

MIDBRAIN - Pig RNA-seqi
Max subtype nTPMi 160.4
Pig sample Sample description nTPM
124.8128.4133.8118.1146.3020406080100120140
 		Substantia nigra
nTPM: 130.3
Samples: 4

Max nTPM: 146.3
Min nTPM: 118.1
Sample A Female 146.3
Sample B Female 118.1
Sample C Male 127.1
Sample D Male 129.7
137.2155.9179.1127.1202.5020406080100120140160180200
 		Midbrain
nTPM: 160.4
Samples: 4

Max nTPM: 202.5
Min nTPM: 127.1
Sample A Female 202.5
Sample B Female 127.1
Sample C Male 171.3
Sample D Male 140.5
120.1122.9124.3117.2125.80102030405060708090100110120
 		Periaqueductal gray
nTPM: 122.0
Samples: 3

Max nTPM: 125.8
Min nTPM: 117.2
Sample B Female 125.8
Sample C Male 122.9
Sample D Male 117.2
141.2150.7158.2133.2160.2020406080100120140160
 		Superior colliculi
nTPM: 148.7
Samples: 4

Max nTPM: 160.2
Min nTPM: 133.2
Sample A Female 157.5
Sample B Female 133.2
Sample C Male 160.2
Sample D Male 143.8

MIDBRAIN - Mouse RNA-seqi
Max subtype nTPMi 137.9
Mouse sample Sample description nTPM
133.5139.0143.3126.4147.1020406080100120140
 		Midbrain
nTPM: 137.9
Samples: 4

Max nTPM: 147.1
Min nTPM: 126.4
Sample A Male 126.4
Sample B Male 142.1
Sample C Female 147.1
Sample D Female 135.9

MIDBRAIN - Allen Mouse ISHi
Max subtype Expression energyi 1.9
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 1.9
71232750 Antisense, RP_050503_01_B07, Mouse strain C57BL/6J (56 days, male) 1.9

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