Expression of SSR1 in skin cancer - The Human Protein Atlas

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SSR1

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Field

Term

Cluster

Cell type

Category

Cluster

Cluster

Pathway

SUMMARY

TISSUE

BRAIN

SINGLE CELL

SUBCELL

CANCER

BLOOD

CELL LINE

STRUCTURE

INTERACTION

SSR1

SKIN CANCER - Protein expressionⁱ A mouse-over function shows sample information and annotation data. Click on an image to view it in a full screen mode. Samples can be filtered based on level of antibody staining by selecting one or several of the following categories: high, medium, low and not detected. The assay and annotation is described here. Note that samples used for immunohistochemistry by the Human Protein Atlas do not correspond to samples in the TCGA dataset.

Antibody stainingⁱ Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells. Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample. Ascending and descending describe two types of gradient, based on difference in staining intensity between enterocytes in crypts and apical enterocytes. Ascending - the staining intensity is stronger in apical enterocytes (towards the lumen) compared to enterocytes in the crypts (gland based) Descending - the staining is weaker in apical enterocytes compared to enterocytes in crypts	Antibody HPA011276		Antibody HPA017062
Staining
High
Medium
Low
Not detected
Intensity
Strong
Moderate
Weak
Negative
Quantity
>75%
75%-25%
<25%
None
Location
Nuclear
Cytoplasmic/membranous
Cytoplasmic/membranous,nuclear
None
Squamous cell carcinoma, NOS
Basal cell carcinoma Adnexal tumor, benign
Basal cell carcinoma
Squamous cell carcinoma in situ, NOS Squamous cell carcinoma, NOS
Squamous cell carcinoma, NOS Squamous cell carcinoma, metastatic, NOS

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.

contact@proteinatlas.org