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The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.
The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".
Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.
Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.
& Survival analysisi
Kaplan-Meier plots summarize results from analysis of correlation between mRNA expression level and patient survival. Patients were divided based on level of expression into one of the two groups "low" (under cut off) or "high" (over cut off). X-axis shows time for survival (years) and y-axis shows the probability of survival, where 1.0 corresponds to 100 percent.
MARK2 is not prognostic in Colon Adenocarcinoma (TCGA)
Stage:
Survival analysis
Current cut offi
Current cut-off shows the cut-off (FPKM) currently selected. It may be changed manually. When the current cut-off is changed, the vertical dashed line indicating cut-off, the interactive survival scatter plot and the Kaplan-Meier curve will be automatically adjusted to show results accordingly.
:
Best expression cut offi
Based on the FPKM value of each gene, patients were classified into two groups and association between prognosis (survival) and gene expression (FPKM) was examined. The best expression cut-off refers the FPKM value that yields maximal difference with regard to survival between the two groups at the lowest log-rank P-value. Best expression cut-off was selected based on survival analysis .
When clicking on this number, the vertical dashed line indicating cut-off, the interactive survival plot, and the Kaplan-Meier curve will be adjusted to show results based on the best expression cut-off.
Median expression refers to the median FPKM value calculated based on the gene expression (FPKM) data from all patients in this dataset. When clicking on this number, the vertical dashed line indicating cut-off, the interactive survival plot, and the Kaplan-Meier curve will be adjusted to show results based on the median expression.
Median follow up time refers to the median time (years) after diagnosis with this type of cancer, based on clinical data from all patients in this dataset.
: N/A
P scorei
Log-rank P value for Kaplan-Meier plot showing results from analysis of correlation between mRNA expression level and patient survival.
N/A
5-year survival highi
5-year survival for patients with higher expression than the expression cutoff.
For melanoma and glioma, 3-year survival is shown.
N/A
5-year survival lowi
5-year survival for patients with lower expression than the expression cutoff.
For melanoma and glioma, 3-year survival is shown.
N/A
TCGA RNA samplesi
RNA-seq data is reported as average FPKM (number Fragments Per Kilobase of exon per Million reads), generated by the The Cancer Genome Atlas (TCGA) .
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. FPKM values of the individual samples are presented next to the box plot.
Average TPM
24.4
Number of samples
254
Samples
Sample
Description
TPM
TCGA-D5-6533-01A
68 years, female, white, stage:'--, alive, 775 days
44.7
TCGA-D5-6922-01A
76 years, male, white, stage:Stage IIIA, alive, 308 days
44.6
TCGA-AA-3713-01A
68 years, male, stage:Stage IV, alive, 579 days
43.9
TCGA-A6-6140-01A
62 years, male, white, stage:Stage IIA, alive, 734 days
43.8
TCGA-D5-6539-01A
45 years, female, white, stage:'--, alive, 380 days
43.7
TCGA-G4-6303-01A
54 years, female, white, stage:Stage IV, dead, 2003 days
43.6
TCGA-DM-A1D0-01A
79 years, female, white, stage:Stage IIA, alive, 3974 days
43.2
TCGA-D5-6920-01A
77 years, female, white, stage:Stage IIA, alive, 377 days
42.1
TCGA-D5-6923-01A
57 years, male, white, stage:Stage I, alive, 378 days
41.8
TCGA-G4-6321-01A
60 years, female, white, stage:Stage III, alive, 672 days
40.8
TCGA-D5-6927-01A
34 years, male, white, stage:Stage IIA, alive, 287 days
40.1
TCGA-F4-6856-01A
45 years, male, white, stage:Stage I, alive, 1074 days
39.9
TCGA-CM-6675-01A
35 years, male, black or african american, stage:Stage IVB, alive, 397 days
39.3
TCGA-QG-A5Z1-01A
71 years, male, black or african american, stage:Stage IIIB, dead, 256 days
39.1
TCGA-A6-2675-01A
78 years, male, white, stage:Stage IIA, alive, 1321 days
38.4
TCGA-AD-6895-01A
84 years, male, white, stage:Stage IIIB, alive, 763 days
38.2
TCGA-F4-6570-01A
78 years, female, white, stage:Stage IIA, dead, 188 days
38.0
TCGA-A6-6649-01A
66 years, male, white, stage:Stage IIIB, alive, 735 days
37.5
TCGA-AD-6965-01A
62 years, male, white, stage:Stage IIIC, alive, 805 days
37.5
TCGA-A6-6648-01A
56 years, male, white, stage:Stage IVA, alive, 766 days
37.1
TCGA-A6-6650-01A
69 years, female, black or african american, stage:Stage IIA, alive, 627 days
36.9
TCGA-SS-A7HO-01A
44 years, female, black or african american, stage:Stage IIB, alive, 1829 days
36.8
TCGA-NH-A6GA-01A
58 years, male, black or african american, stage:Stage IIIC, dead, 302 days
36.7
TCGA-D5-6538-01A
79 years, female, white, stage:Stage IIIB, alive, 521 days
35.3
TCGA-AZ-6603-01A
77 years, female, white, stage:'--, dead, 899 days
35.3
TCGA-CK-5913-01A
58 years, female, white, stage:Stage IIA, alive, 1561 days
35.0
TCGA-AY-6197-01A
60 years, male, white, stage:Stage IIA, alive, 652 days
35.0
TCGA-CM-6165-01A
74 years, male, white, stage:Stage IIA, alive, 488 days
34.9
TCGA-AZ-6607-01A
69 years, male, white, stage:Stage IV, dead, 97 days
34.9
TCGA-D5-6926-01A
65 years, male, white, stage:Stage IIIB, alive, 275 days
34.7
TCGA-D5-6931-01A
77 years, male, white, stage:Stage IIIC, alive, 365 days
34.6
TCGA-CA-6718-01A
46 years, male, asian, stage:Stage IIA, dead, 306 days
34.3
TCGA-AU-6004-01A
69 years, female, white, stage:Stage I, alive, 824 days
34.0
TCGA-F4-6459-01A
61 years, female, white, stage:Stage IIIB, dead, 262 days
34.0
TCGA-D5-6535-01A
80 years, female, white, stage:Stage IIIB, alive, 460 days
33.8
TCGA-A6-6142-01A
56 years, female, white, stage:Stage IVA, alive, 763 days
33.8
TCGA-A6-6137-01A
55 years, male, white, stage:Stage IIIB, alive, 824 days
33.7
TCGA-AY-6386-01A
66 years, female, black or african american, stage:Stage IIIB, alive, 542 days
33.5
TCGA-DM-A28F-01A
73 years, male, white, stage:Stage IIIB, dead, 1094 days
33.3
TCGA-G4-6295-01A
70 years, female, white, stage:Stage II, alive, 254 days
33.1
TCGA-CK-6747-01A
87 years, female, white, stage:Stage IIA, alive, 820 days
32.9
TCGA-D5-6534-01A
62 years, female, white, stage:Stage IIA, alive, 1316 days
32.6
TCGA-D5-6898-01A
51 years, female, white, stage:Stage I, alive, 229 days
32.4
TCGA-CM-6162-01A
48 years, female, white, stage:Stage IIIB, alive, 365 days
32.2
TCGA-F4-6805-01A
58 years, female, white, stage:Stage IIA, alive, 1047 days
32.1
TCGA-AA-3655-01A
68 years, male, stage:Stage II, alive, 1856 days
32.0
TCGA-AY-A8YK-01A
44 years, male, black or african american, stage:Stage IVA, alive, 573 days
32.0
TCGA-CA-5797-01A
56 years, male, asian, stage:Stage IIA, alive, 383 days
31.6
TCGA-G4-6314-01A
76 years, female, white, stage:Stage IV, alive, 1093 days
31.5
TCGA-F4-6854-01A
77 years, female, white, stage:Stage IIA, alive, 16 days
31.3
TCGA-AD-6899-01A
84 years, male, white, stage:Stage IIIC, dead, 176 days
31.3
TCGA-A6-5657-01A
65 years, male, black or african american, stage:Stage IIIB, alive, 962 days
31.3
TCGA-CM-6170-01A
73 years, female, white, stage:Stage I, alive, 457 days
31.2
TCGA-G4-6311-01A
80 years, male, white, stage:Stage III, alive, 1199 days
31.2
TCGA-AD-6548-01A
81 years, female, white, stage:Stage I, alive, 650 days
31.1
TCGA-D5-6530-01A
53 years, male, white, stage:Stage I, alive, 621 days
31.0
TCGA-CM-5348-01A
72 years, male, white, stage:Stage IIIB, alive, 699 days
30.9
TCGA-CK-5912-01A
81 years, male, white, stage:Stage I, dead, 1493 days
30.9
TCGA-DM-A28C-01A
74 years, male, white, stage:Stage IIA, dead, 2475 days
30.6
TCGA-G4-6309-01A
40 years, female, black or african american, stage:Stage IIIB, alive, 2600 days
30.1
TCGA-D5-7000-01A
79 years, female, white, stage:Stage I, alive, 312 days
30.1
TCGA-F4-6807-01A
51 years, female, white, stage:Stage IIIC, alive, 1309 days
30.1
TCGA-QG-A5Z2-01A
61 years, male, black or african american, stage:Stage I, alive, 952 days
30.0
TCGA-CM-6164-01A
46 years, female, white, stage:Stage IIA, alive, 883 days
30.0
TCGA-CK-4952-01A
48 years, female, white, stage:Stage IIIC, alive, 475 days
29.7
TCGA-QG-A5YX-01A
61 years, female, black or african american, stage:Stage IIA, alive, 1003 days
29.7
TCGA-AZ-6606-01A
81 years, male, white, stage:Stage IV, dead, 357 days
29.3
TCGA-CA-6715-01A
63 years, male, asian, stage:Stage IIIB, alive, 383 days
29.0
TCGA-T9-A92H-01A
82 years, male, black or african american, stage:Stage IIA, alive, 362 days
29.0
TCGA-A6-6781-01A
43 years, male, white, stage:Stage IIIC, alive, 598 days
29.0
TCGA-D5-5538-01A
60 years, female, white, stage:Stage IIIB, dead, 1661 days
28.9
TCGA-A6-5667-01A
40 years, female, white, stage:Stage IIIB, alive, 887 days
28.6
TCGA-A6-6652-01A
59 years, male, black or african american, stage:Stage IVA, alive, 751 days
28.6
TCGA-F4-6460-01A
51 years, female, white, stage:Stage IIIB, dead, 972 days
28.5
TCGA-WS-AB45-01A
52 years, female, black or african american, stage:Stage IIA, alive, 2130 days
28.4
TCGA-G4-6625-01A
77 years, female, white, stage:Stage IIA, alive, 2792 days
28.4
TCGA-D5-6532-01A
61 years, male, white, stage:Stage IIA, alive, 555 days
28.3
TCGA-NH-A8F7-01A
53 years, female, black or african american, stage:Stage IIA, alive, 543 days
28.3
TCGA-D5-6540-01A
66 years, male, white, stage:Stage I, alive, 491 days
28.3
TCGA-G4-6297-01A
55 years, female, white, stage:Stage IV, alive, 2506 days
27.9
TCGA-G4-6586-01A
73 years, female, white, stage:Stage IIA, alive, 1089 days
27.9
TCGA-AM-5820-01A
59 years, female, white, stage:Stage IVA, alive, 14 days
27.9
TCGA-F4-6461-01A
41 years, female, white, stage:Stage IIIC, dead, 338 days
27.8
TCGA-CM-4751-01A
62 years, male, white, stage:Stage IIIB, alive, 822 days
27.7
TCGA-AZ-6601-01A
68 years, male, white, stage:Stage II, dead, 3042 days
27.6
TCGA-A6-A565-01A
34 years, female, black or african american, stage:Stage IIIC, dead, 494 days
27.6
TCGA-CM-6161-01A
36 years, female, white, stage:Stage I, alive, 457 days
27.5
TCGA-CM-6169-01A
67 years, male, black or african american, stage:Stage IIA, alive, 396 days
27.5
TCGA-DM-A285-01A
71 years, female, white, stage:Stage IV, dead, 179 days
27.4
TCGA-A6-6138-01A
61 years, male, white, stage:Stage I, alive, 685 days
27.3
TCGA-G4-6299-01A
69 years, male, white, stage:Stage IIIC, alive, 2268 days
27.1
TCGA-NH-A50U-01A
42 years, male, black or african american, stage:Stage IVA, dead, 334 days
26.9
TCGA-D5-6932-01A
69 years, male, white, stage:Stage IIA, alive, 346 days
26.7
TCGA-AY-A69D-01A
55 years, female, black or african american, stage:Stage IIA, alive, 543 days
26.7
TCGA-CA-6719-01A
77 years, male, asian, stage:Stage IIA, alive, 435 days
26.7
TCGA-AZ-6600-01A
64 years, male, black or african american, stage:Stage IV, dead, 368 days
26.6
TCGA-A6-5664-01A
80 years, male, black or african american, stage:Stage IIIC, alive, 672 days
26.6
TCGA-A6-5661-01A
80 years, female, black or african american, stage:Stage IIA, alive, 1020 days
26.5
TCGA-CM-6168-01A
84 years, female, black or african american, stage:Stage IIA, alive, 395 days
26.4
TCGA-G4-6306-01A
71 years, male, white, stage:'--, alive, 1359 days
26.3
TCGA-A6-A567-01A
56 years, male, black or african american, stage:Stage IV, dead, 1881 days
26.2
TCGA-CA-5254-01A
42 years, female, asian, stage:Stage IIA, alive, 386 days
26.0
TCGA-CM-6676-01A
82 years, male, white, stage:Stage I, alive, 337 days
26.0
TCGA-CK-5916-01A
71 years, female, white, stage:Stage I, dead, 643 days
25.9
TCGA-CK-4950-01A
68 years, female, black or african american, stage:Stage IIIB, alive, 2599 days
25.8
TCGA-AD-6963-01A
58 years, male, white, stage:'--, alive, 834 days
25.8
TCGA-CM-6171-01A
77 years, female, white, stage:Stage I, alive, 427 days
25.8
TCGA-A6-5662-01A
46 years, male, white, stage:Stage IVA, alive, 718 days
25.6
TCGA-D5-6924-01A
68 years, male, white, stage:Stage IIA, alive, 435 days
25.5
TCGA-AA-3660-01A
51 years, female, stage:Stage II, alive, 2375 days
25.4
TCGA-DM-A28A-01A
78 years, male, white, stage:Stage IIIC, dead, 805 days
25.4
TCGA-CA-6716-01A
65 years, male, asian, stage:Stage IIA, alive, 371 days
25.4
TCGA-F4-6569-01A
60 years, male, white, stage:Stage I, alive, 1087 days
25.1
TCGA-G4-6626-01A
90 years, male, white, stage:Stage IIA, dead, 1 days
25.1
TCGA-G4-6307-01A
37 years, female, white, stage:Stage IIIB, alive, 1674 days
25.0
TCGA-QL-A97D-01A
84 years, female, black or african american, stage:Stage I, alive, 666 days
24.8
TCGA-CM-6680-01A
78 years, female, white, stage:Stage IIIB, alive, 366 days
24.7
TCGA-CA-6717-01A
57 years, male, asian, stage:Stage IIA, alive, 388 days
24.3
TCGA-AZ-6599-01A
72 years, male, white, stage:Stage I, dead, 206 days
24.3
TCGA-F4-6704-01A
60 years, male, american indian or alaska native, stage:Stage IIIC, alive, 47 days
24.2
TCGA-QG-A5YV-01A
64 years, female, black or african american, stage:Stage IIIC, alive, 1301 days
24.1
TCGA-A6-6653-01A
82 years, male, white, stage:Stage I, alive, 742 days
24.0
TCGA-DM-A28E-01A
72 years, female, white, stage:Stage IIA, alive, 3648 days
24.0
TCGA-CM-6679-01A
58 years, male, white, stage:Stage IIA, alive, 306 days
23.9
TCGA-A6-5665-01A
84 years, female, white, stage:Stage IIA, alive, 671 days
23.7
TCGA-A6-A56B-01A
57 years, male, black or african american, stage:Stage IIIB, dead, 1711 days
23.5
TCGA-NH-A8F8-01A
79 years, male, black or african american, stage:Stage IV, dead, 511 days
23.5
TCGA-G4-6315-01A
66 years, male, white, stage:Stage IV, alive, 1883 days
23.4
TCGA-D5-6531-01A
75 years, male, white, stage:Stage IIA, alive, 540 days
23.3
TCGA-D5-6928-01A
80 years, male, white, stage:Stage IIA, alive, 354 days
23.3
TCGA-AA-3496-01A
83 years, female, stage:Stage II, alive, 31 days
23.2
TCGA-AD-5900-01A
67 years, male, white, stage:Stage I, alive, 370 days
23.1
TCGA-A6-6780-01A
74 years, male, white, stage:Stage IIA, alive, 612 days
23.1
TCGA-A6-A5ZU-01A
59 years, male, black or african american, stage:Stage IIIB, alive, 293 days
22.8
TCGA-D5-6930-01A
67 years, male, white, stage:Stage IIA, alive, 406 days
22.8
TCGA-AA-3511-01A
64 years, male, stage:Stage II, alive, 212 days
22.8
TCGA-G4-6588-01A
58 years, female, white, stage:Stage IIA, alive, 796 days
22.8
TCGA-DM-A1DB-01A
68 years, male, white, stage:Stage IIA, dead, 1348 days
22.6
TCGA-AA-3697-01A
77 years, male, stage:Stage II, alive, 2587 days
22.4
TCGA-A6-2674-01A
71 years, male, white, stage:Stage IV, alive, 1331 days
22.4
TCGA-NH-A6GB-01A
71 years, female, black or african american, stage:Stage IIIC, alive, 476 days
22.3
TCGA-CM-6674-01A
39 years, male, white, stage:Stage IIA, alive, 394 days
22.1
TCGA-A6-6141-01A
31 years, male, black or african american, stage:Stage IIA, alive, 255 days
22.1
TCGA-F4-6463-01A
51 years, male, white, stage:Stage IIA, alive, 1087 days
22.0
TCGA-AZ-6598-01A
77 years, female, white, stage:Stage II, dead, 1503 days
22.0
TCGA-AA-3489-01A
75 years, male, stage:Stage II, dead, 214 days
21.9
TCGA-G4-6627-01A
84 years, male, white, stage:Stage IIA, alive, 2175 days
21.8
TCGA-CM-5861-01A
63 years, female, white, stage:Stage IIA, alive, 457 days
21.6
TCGA-A6-5660-01A
73 years, male, black or african american, stage:Stage IIIC, alive, 888 days
21.3
TCGA-CM-5863-01A
60 years, female, white, stage:Stage IIIB, alive, 457 days
21.3
TCGA-AD-6890-01A
65 years, male, white, stage:'--, alive, 746 days
21.3
TCGA-AD-6888-01A
73 years, male, white, stage:Stage IIIB, dead, 472 days
21.1
TCGA-G4-6322-01A
65 years, male, white, stage:Stage IIIB, alive, 792 days
21.1
TCGA-NH-A50V-01A
69 years, male, black or african american, stage:Stage IIIB, alive, 588 days
21.1
TCGA-CA-5255-01A
45 years, male, asian, stage:Stage IIA, alive, 376 days
20.9
TCGA-4N-A93T-01A
67 years, male, black or african american, stage:Stage IIIB, alive, 146 days
20.9
TCGA-G4-6628-01A
78 years, male, white, stage:Stage I, alive, 2424 days
20.9
TCGA-3L-AA1B-01A
61 years, female, black or african american, stage:Stage I, alive, 475 days
20.9
TCGA-5M-AAT4-01A
74 years, male, black or african american, stage:Stage IV, dead, 49 days
20.8
TCGA-A6-4105-01A
79 years, male, white, stage:Stage IIA, dead, 442 days
20.8
TCGA-F4-6806-01A
59 years, female, white, stage:Stage I, alive, 1260 days
20.7
TCGA-AZ-6608-01A
55 years, female, white, stage:Stage IIIA, dead, 59 days
20.7
TCGA-AY-5543-01A
65 years, female, black or african american, stage:Stage IVA, alive, 1004 days
20.7
TCGA-AA-A02K-01A
50 years, male, stage:Stage IV, dead, 426 days
20.6
TCGA-G4-6293-01A
49 years, female, white, stage:Stage III, alive, 4051 days
20.6
TCGA-D5-5539-01A
60 years, male, white, stage:Stage IIIA, alive, 596 days
20.6
TCGA-AA-3675-01A
84 years, male, stage:Stage II, alive, 1431 days
20.6
TCGA-F4-6808-01A
54 years, female, white, stage:Stage I, alive, 1024 days
20.4
TCGA-CK-6748-01A
45 years, female, white, stage:Stage IV, alive, 61 days
20.3
TCGA-F4-6703-01A
64 years, male, white, stage:Stage IIA, alive, 1456 days
20.2
TCGA-CK-6751-01A
88 years, female, white, stage:Stage I, alive, 518 days
20.2
TCGA-DM-A0XF-01A
68 years, female, white, stage:Stage IIIC, dead, 1162 days
20.2
TCGA-DM-A1HA-01A
82 years, male, white, stage:Stage IIIC, alive, 2600 days
20.0
TCGA-F4-6809-01A
52 years, female, white, stage:Stage IVA, dead, 403 days
19.9
TCGA-A6-5656-01A
74 years, male, white, stage:Stage I, alive, 1001 days
19.8
TCGA-G4-6310-01A
69 years, male, white, stage:Stage IIIB, alive, 1935 days
19.8
TCGA-A6-5659-01A
82 years, male, white, stage:Stage I, alive, 926 days
19.7
TCGA-QG-A5YW-01A
55 years, female, black or african american, stage:Stage IIIC, alive, 896 days
19.6
TCGA-G4-6304-01A
66 years, female, white, stage:Stage IIB, alive, 1631 days
19.4
TCGA-F4-6855-01A
70 years, female, white, stage:Stage IIA, alive, 1442 days
19.4
TCGA-A6-6654-01A
65 years, female, white, stage:Stage IIIB, alive, 726 days
19.2
TCGA-DM-A1D9-01A
67 years, female, white, stage:Stage IIA, alive, 4270 days
19.2
TCGA-AZ-5403-01A
43 years, male, white, stage:Stage II, dead, 1910 days
19.2
TCGA-AD-6889-01A
76 years, male, asian, stage:Stage IIA, dead, 2532 days
19.1
TCGA-CM-6677-01A
75 years, female, white, stage:Stage IIA, alive, 337 days
19.1
TCGA-D5-6929-01A
49 years, female, white, stage:Stage IV, alive, 408 days
19.0
TCGA-D5-5537-01A
83 years, male, white, stage:'--, dead, 1381 days
19.0
TCGA-AA-A02Y-01A
73 years, male, stage:Stage I, alive, 1216 days
19.0
TCGA-CM-6172-01A
70 years, female, white, stage:Stage IIIB, alive, 335 days
18.8
TCGA-AZ-6605-01A
77 years, male, white, stage:Stage IIIB, dead, 159 days
18.7
TCGA-A6-3809-01A
71 years, female, white, stage:Stage IIB, alive, 996 days
18.7
TCGA-5M-AAT6-01A
40 years, female, black or african american, stage:Stage IV, dead, 290 days
18.6
TCGA-CM-6166-01A
48 years, female, white, stage:Stage I, alive, 669 days
18.6
TCGA-D5-6529-01A
69 years, male, white, stage:Stage IIA, alive, 614 days
18.5
TCGA-AY-6196-01A
47 years, male, white, stage:Stage IIIC, alive, 6 days
18.5
TCGA-5M-AATE-01A
76 years, male, black or african american, stage:Stage IIA, alive, 1200 days
18.5
TCGA-NH-A6GC-01A
66 years, female, black or african american, stage:Stage IVB, alive, 389 days
18.4
TCGA-CM-6163-01A
74 years, male, white, stage:Stage I, alive, 427 days
18.4
TCGA-DM-A28H-01A
50 years, male, white, stage:Stage IIIC, alive, 3561 days
18.3
TCGA-D5-6541-01A
49 years, male, white, stage:Stage IIA, alive, 474 days
18.1
TCGA-D5-6537-01A
64 years, male, white, stage:Stage IIIB, dead, 146 days
17.9
TCGA-AD-6964-01A
58 years, male, white, stage:'--, dead, 331 days
17.7
TCGA-AD-6901-01A
78 years, male, white, stage:'--, dead, 682 days
17.7
TCGA-CK-5914-01A
81 years, male, white, stage:Stage IIIB, alive, 669 days
17.6
TCGA-AA-3663-01A
42 years, male, stage:Stage II, alive, 212 days
17.5
TCGA-AZ-5407-01A
51 years, female, white, stage:Stage I, alive, 2683 days
17.5
TCGA-4T-AA8H-01A
42 years, female, black or african american, stage:Stage IIA, alive, 385 days
17.5
TCGA-DM-A1D7-01A
82 years, male, white, stage:Stage IIA, dead, 405 days
17.5
TCGA-A6-6651-01A
55 years, female, white, stage:Stage IIIB, alive, 662 days
17.4
TCGA-AA-3526-01A
57 years, male, stage:Stage I, alive, 580 days
17.4
TCGA-AA-3662-01A
80 years, female, stage:Stage IV, alive, 184 days
17.2
TCGA-DM-A1HB-01A
75 years, male, white, stage:Stage IIIB, alive, 4126 days
17.2
TCGA-AZ-4323-01A
37 years, male, white, stage:Stage IV, dead, 43 days
17.1
TCGA-G4-6323-01A
50 years, male, black or african american, stage:Stage IA, alive, 419 days
17.1
TCGA-G4-6294-01A
75 years, male, white, stage:Stage IV, dead, 858 days
16.8
TCGA-A6-3810-01A
62 years, male, white, stage:Stage IIA, alive, 1111 days
16.7
TCGA-DM-A1DA-01A
71 years, female, white, stage:Stage IIIC, dead, 228 days
16.7
TCGA-CM-5344-01A
39 years, female, white, stage:Stage IIIB, alive, 670 days
16.3
TCGA-CM-6167-01A
57 years, female, black or african american, stage:Stage IIIC, alive, 456 days
16.2
TCGA-G4-6320-01A
73 years, male, white, stage:Stage III, alive, 804 days
15.7
TCGA-A6-6782-01A
82 years, male, white, stage:Stage IIB, alive, 617 days
15.5
TCGA-A6-A566-01A
55 years, female, black or african american, stage:Stage IIIB, dead, 758 days
15.5
TCGA-CM-5868-01A
59 years, female, white, stage:Stage IVA, alive, 518 days
15.2
TCGA-DM-A1D8-01A
50 years, female, white, stage:'--, dead, 383 days
15.2
TCGA-AD-A5EK-01A
51 years, male, black or african american, stage:Stage I, alive, 500 days
15.2
TCGA-AZ-4616-01A
82 years, female, white, stage:Stage IV, dead, 156 days
15.2
TCGA-AU-3779-01A
80 years, female, white, stage:Stage IIA, alive, 441 days
15.1
TCGA-DM-A28K-01A
75 years, male, white, stage:Stage IIA, alive, 2988 days
15.0
TCGA-DM-A0X9-01A
71 years, female, white, stage:Stage IIA, alive, 3641 days
15.0
TCGA-RU-A8FL-01A
51 years, male, black or african american, stage:Stage IIIB, alive, 1177 days
15.0
TCGA-CM-5860-01A
44 years, male, white, stage:Stage IIA, alive, 974 days
14.7
TCGA-G4-6317-01A
51 years, female, white, stage:Stage IIIC, alive, 1095 days
14.7
TCGA-AY-A54L-01A
74 years, female, black or african american, stage:Stage I, alive, 525 days
14.4
TCGA-A6-5666-01A
78 years, male, white, stage:Stage IIC, alive, 995 days
14.0
TCGA-CM-6678-01A
63 years, female, white, stage:Stage IVA, alive, 335 days
13.4
TCGA-AM-5821-01A
68 years, female, white, stage:Stage IIA, alive, 28 days
13.4
TCGA-A6-2686-01A
81 years, female, white, stage:Stage IIA, dead, 1126 days
13.2
TCGA-AY-A71X-01A
54 years, female, black or african american, stage:Stage I, alive, 588 days
13.1
TCGA-DM-A1D4-01A
80 years, male, white, stage:Stage IIA, dead, 2821 days
12.3
TCGA-DM-A280-01A
70 years, female, white, stage:Stage IIA, dead, 236 days
12.2
TCGA-DM-A282-01A
60 years, female, white, stage:Stage IIA, alive, 4233 days
12.2
TCGA-DM-A28M-01A
63 years, male, white, stage:Stage IIA, alive, 2895 days
11.8
TCGA-CM-4743-01A
69 years, male, white, stage:Stage IIA, alive, 701 days
11.5
TCGA-DM-A288-01A
68 years, male, white, stage:Stage IIIC, dead, 427 days
11.4
TCGA-DM-A28G-01A
75 years, male, white, stage:Stage IIA, dead, 1849 days
11.4
TCGA-AA-3685-01A
69 years, male, stage:Stage II, alive, 1127 days
11.0
TCGA-NH-A50T-01A
68 years, female, black or african american, stage:Stage IIA, alive, 553 days
10.9
TCGA-CM-5864-01A
60 years, male, white, stage:Stage I, alive, 457 days
10.5
TCGA-DM-A0XD-01A
65 years, male, white, stage:Stage IIA, dead, 743 days
9.9
TCGA-D5-6536-01A
73 years, male, white, stage:Stage IIA, alive, 543 days
9.8
TCGA-DM-A1D6-01A
88 years, male, white, stage:Stage IIA, dead, 570 days
9.4
TCGA-CM-4744-01A
69 years, male, white, stage:Stage I, alive, 609 days
9.4
TCGA-CM-5862-01A
80 years, male, white, stage:Stage IVA, dead, 153 days
9.4
TCGA-CM-5349-01A
68 years, female, white, stage:Stage IIA, alive, 915 days
The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.
The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".
Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.
Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.
& Survival analysisi
Kaplan-Meier plots summarize results from analysis of correlation between mRNA expression level and patient survival. Patients were divided based on level of expression into one of the two groups "low" (under cut off) or "high" (over cut off). X-axis shows time for survival (years) and y-axis shows the probability of survival, where 1.0 corresponds to 100 percent.
MARK2 is not prognostic in Colon Adenocarcinoma (validation)
Stage:
Survival analysis
Current cut offi
Current cut-off shows the cut-off (FPKM) currently selected. It may be changed manually. When the current cut-off is changed, the vertical dashed line indicating cut-off, the interactive survival scatter plot and the Kaplan-Meier curve will be automatically adjusted to show results accordingly.
:
Best expression cut offi
Based on the FPKM value of each gene, patients were classified into two groups and association between prognosis (survival) and gene expression (FPKM) was examined. The best expression cut-off refers the FPKM value that yields maximal difference with regard to survival between the two groups at the lowest log-rank P-value. Best expression cut-off was selected based on survival analysis .
When clicking on this number, the vertical dashed line indicating cut-off, the interactive survival plot, and the Kaplan-Meier curve will be adjusted to show results based on the best expression cut-off.
Median expression refers to the median FPKM value calculated based on the gene expression (FPKM) data from all patients in this dataset. When clicking on this number, the vertical dashed line indicating cut-off, the interactive survival plot, and the Kaplan-Meier curve will be adjusted to show results based on the median expression.
Median follow up time refers to the median time (years) after diagnosis with this type of cancer, based on clinical data from all patients in this dataset.
: N/A
P scorei
Log-rank P value for Kaplan-Meier plot showing results from analysis of correlation between mRNA expression level and patient survival.
N/A
5-year survival highi
5-year survival for patients with higher expression than the expression cutoff.
For melanoma and glioma, 3-year survival is shown.
N/A
5-year survival lowi
5-year survival for patients with lower expression than the expression cutoff.
For melanoma and glioma, 3-year survival is shown.
N/A
TCGA RNA samplesi
RNA-seq data is reported as average FPKM (number Fragments Per Kilobase of exon per Million reads), generated by the The Cancer Genome Atlas (TCGA) .
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. FPKM values of the individual samples are presented next to the box plot.
Average TPM
52.1
Number of samples
486
Samples
Sample
Description
TPM
U3032
61 years, female, NA, stage:T3N1M0, alive, 449 days
90.2
U3008
82 years, female, NA, stage:T2N0M0, alive, 473 days
87.1
U0275
69 years, female, NA, stage:T3N2M0, alive, 549 days
80.7
U2882
65 years, female, NA, stage:T3N1M0, alive, 637 days
79.4
U0157
83 years, male, NA, stage:T4N0M0, dead, 131 days
78.3
U1264
69 years, female, NA, stage:T3N0M0, dead, 1583 days
78.2
U0427
59 years, male, NA, stage:T2N0M0, alive, 1193 days
78.0
U1074
77 years, male, NA, stage:T3N0M0, dead, 1043 days
78.0
U0404
57 years, female, NA, stage:T3N2M0, dead, 204 days
77.4
U0104
87 years, female, NA, stage:T4N0M0, dead, 1639 days
76.4
U1447
57 years, male, NA, stage:T4N1M0, alive, 988 days
76.2
U0217
76 years, female, NA, stage:T3N0M0, dead, 538 days
76.1
U0063
95 years, male, NA, stage:T1N0M0, dead, 1779 days
75.9
U0002
82 years, female, NA, stage:T3N2M0, alive, 3691 days
75.3
U1040
83 years, male, NA, stage:T2N0M0, alive, 1029 days
74.9
U0464
49 years, male, NA, stage:T3N0M0, alive, 918 days
74.8
U2803
66 years, male, NA, stage:T3N1M0, alive, 744 days
74.4
U2754
81 years, male, NA, stage:T4N0M0, alive, 809 days
74.3
U2798
68 years, male, NA, stage:T3N0M0, alive, 751 days
73.1
U0292
71 years, male, NA, stage:T4N1M0, alive, 1666 days
72.8
U2979
73 years, male, NA, stage:T3N2M0, alive, 616 days
72.4
U1374
66 years, male, NA, stage:T4N0M0, alive, 827 days
72.1
U0399
63 years, female, NA, stage:T4N2M0, dead, 547 days
72.1
U0185
80 years, male, NA, stage:T1N0M0, alive, 1248 days
72.1
U1276
66 years, male, NA, stage:T3N0M0, alive, 2474 days
72.0
U0215
77 years, male, NA, stage:T3N0M0, alive, 1269 days
71.9
U0937
86 years, male, NA, stage:T2N0M0, dead, 1558 days
71.8
U0221
77 years, male, NA, stage:T3N0M0, alive, 569 days
71.7
U2942
74 years, male, NA, stage:T2N0M0, alive, 549 days
71.6
U0949
84 years, female, NA, stage:T3N0M1, dead, 594 days
71.5
U0977
84 years, female, NA, stage:T4N2M0, dead, 140 days
71.3
U0191
80 years, male, NA, stage:T3N1M0, alive, 900 days
71.1
U0127
80 years, female, NA, stage:T3N0M0, dead, 2753 days
71.0
U1421
59 years, female, NA, stage:T3N1M0, alive, 1905 days
70.8
U2843
89 years, female, NA, stage:T3N0M0, alive, 674 days
70.6
U1078
80 years, female, NA, stage:T3N0M0, alive, 1016 days
70.2
U0239
76 years, male, NA, stage:T2N0M0, alive, 67 days
70.1
U2971
62 years, male, NA, stage:T4aN0M0, alive, 629 days
69.9
U2891
81 years, male, NA, stage:T3N1M0, alive, 619 days
69.5
U0203
77 years, male, NA, stage:T3N0M0, dead, 827 days
69.1
U3122
85 years, female, NA, stage:T3N0M1, dead, 91 days
69.0
U0444
52 years, female, NA, stage:T4N1M0, alive, 1841 days
68.9
U0987
82 years, female, NA, stage:T3N0M0, alive, 2482 days
68.8
U0181
74 years, female, NA, stage:T1N0M0, alive, 3623 days
68.7
U0915
88 years, female, NA, stage:T3N0M0, alive, 1613 days
68.7
U0198
77 years, male, NA, stage:T3N1M0, alive, 1272 days
68.4
U1303
66 years, male, NA, stage:T4N1M0, alive, 2283 days
68.2
U2774
66 years, female, NA, stage:T3N0M0, alive, 783 days
68.2
U0323
69 years, male, NA, stage:T2N0M0, dead, 1016 days
68.1
U0929
85 years, male, NA, stage:T4N1M0, alive, 436 days
67.7
U2837
76 years, female, NA, stage:T4N1M0, alive, 681 days
67.4
U2935
70 years, male, NA, stage:T4N1M0, alive, 555 days
67.3
U0950
86 years, female, NA, stage:T4N1M0, alive, 1834 days
67.1
U0267
73 years, male, NA, stage:T4N0M0, dead, 445 days
67.1
U0414
60 years, male, NA, stage:T3N0M0, alive, 1691 days
67.0
U2981
74 years, male, NA, stage:T3N0M0, alive, 508 days
66.7
U1401
60 years, female, NA, stage:T3N0M0, alive, 1482 days
66.6
U2995
81 years, female, NA, stage:T3N1M0, alive, 491 days
66.4
U1432
60 years, female, NA, stage:T3N1M0, alive, 577 days
66.4
U0967
84 years, male, NA, stage:T2N0M0, dead, 1691 days
66.0
U2861
78 years, male, NA, stage:T3N0M0, alive, 652 days
65.9
U0163
81 years, male, NA, stage:T4N0M0, alive, 697 days
65.7
U0387
65 years, male, NA, stage:T2N0M0, alive, 1327 days
65.5
U0474
30 years, male, NA, stage:T3N1M0, alive, 1017 days
65.4
U2956
86 years, female, NA, stage:T3N0M0, alive, 540 days
65.4
U2927
51 years, male, NA, stage:T3N1M0, alive, 564 days
65.2
U1045
80 years, female, NA, stage:T4N2M0, alive, 1239 days
65.1
U0589
56 years, female, NA, stage:T3N0M0, alive, 1176 days
65.1
U0078
91 years, female, NA, stage:T3N0M0, alive, 1183 days
65.1
U2782
79 years, male, NA, stage:T3N1M1, alive, 773 days
65.1
U2896
81 years, female, NA, stage:T3N1M0, alive, 609 days
65.0
U1291
68 years, female, NA, stage:T3N0M0, alive, 2000 days
65.0
U0360
67 years, female, NA, stage:T3N0M0, dead, 1016 days
64.8
U3037
63 years, male, NA, stage:T3N1M0, alive, 405 days
64.6
U0451
47 years, female, NA, stage:T4N2M0, alive, 3023 days
64.6
U0356
68 years, male, NA, stage:T4N1M0, alive, 536 days
64.5
U1239
69 years, male, NA, stage:T2N0M0, dead, 1998 days
64.4
U2958
84 years, female, NA, stage:T1N0M0, alive, 536 days
64.4
U0328
66 years, male, NA, stage:T4N0M0, dead, 1362 days
64.3
U0976
82 years, female, NA, stage:T3N2M0, dead, 97 days
64.1
U2747
85 years, female, NA, stage:T4N1M0, dead, 54 days
64.0
U0438
53 years, female, NA, stage:T3N0M0, alive, 2009 days
63.9
U2959
63 years, male, NA, stage:T3N2M0, alive, 536 days
63.8
U2753
81 years, female, NA, stage:T2N0M0, alive, 813 days
63.8
U0162
82 years, female, NA, stage:T3N0M0, alive, 1488 days
63.8
U1129
74 years, male, NA, stage:T3N0M0, dead, 118 days
63.6
U2815
82 years, female, NA, stage:T3N0M0, alive, 717 days
63.6
U0378
66 years, female, NA, stage:T4N1M0, dead, 815 days
63.5
U0195
73 years, male, NA, stage:T3N0M0, alive, 3326 days
63.5
U0112
86 years, female, NA, stage:T3N0M1, alive, 551 days
63.5
U1448
53 years, male, NA, stage:T3N0M1, dead, 1512 days
63.3
U3039
74 years, male, NA, stage:T4N1M1, dead, 366 days
63.1
U0168
81 years, male, NA, stage:T3N0M0, dead, 948 days
62.9
U0253
74 years, female, NA, stage:T3N0M0, alive, 958 days
62.9
U2780
75 years, male, NA, stage:T3N0M0, alive, 778 days
62.7
U1352
61 years, male, NA, stage:T3N2M1, dead, 741 days
62.6
U0186
73 years, female, NA, stage:T2N0M0, alive, 3726 days
62.6
U1060
78 years, male, NA, stage:T3N0M0, alive, 2442 days
62.6
U1251
69 years, male, NA, stage:T4N2M0, alive, 126 days
62.4
U0435
52 years, female, NA, stage:T2N0M0, alive, 3616 days
62.4
U1095
76 years, female, NA, stage:T3N1M1, alive, 2425 days
62.3
U0179
75 years, male, NA, stage:T3N1M0, dead, 1043 days
62.3
U0111
88 years, male, NA, stage:T2N0M0, alive, 1117 days
62.2
U0082
85 years, female, NA, stage:T3N1M0, dead, 2339 days
62.1
U1032
80 years, male, NA, stage:T3N1M0, alive, 2113 days
62.1
U1429
58 years, female, NA, stage:T3N0M0, alive, 1660 days
62.0
U0122
85 years, female, NA, stage:T2N0M0, dead, 159 days
61.6
U0250
74 years, female, NA, stage:T4N0M0, dead, 906 days
61.5
U0472
32 years, male, NA, stage:TXN2M0, alive, 542 days
61.5
U1102
77 years, male, NA, stage:T2N0M0, alive, 1354 days
61.4
U0144
84 years, male, NA, stage:T3N0M0, alive, 1218 days
61.3
U0231
77 years, female, NA, stage:T2N0M0, alive, 991 days
61.3
U0446
53 years, male, NA, stage:T2N0M0, alive, 1446 days
61.3
U0898
90 years, female, NA, stage:T4aN0M0, dead, 340 days
61.2
U1274
69 years, male, NA, stage:T2N1M0, alive, 1198 days
61.1
U1047
75 years, female, NA, stage:T4N2M0, alive, 3592 days
61.0
U1162
73 years, male, NA, stage:T2N1M0, dead, 354 days
61.0
U0068
92 years, female, NA, stage:T3N1M0, alive, 1991 days
61.0
U0447
51 years, male, NA, stage:T4N1M0, dead, 1819 days
60.9
U3051
48 years, male, NA, stage:T3N2M0, alive, 415 days
60.8
U0469
42 years, male, NA, stage:T3N0M0, dead, 409 days
60.7
U0463
49 years, male, NA, stage:T3N0M0, alive, 946 days
60.4
U3048
57 years, male, NA, stage:T4N2M0, alive, 535 days
60.3
U0439
56 years, male, NA, stage:T3N1M0, alive, 1418 days
60.3
U2856
71 years, female, NA, stage:T4N1M1, alive, 660 days
60.2
U0999
84 years, male, NA, stage:T3N2M0, alive, 860 days
60.1
U0278
73 years, female, NA, stage:T2N0M0, alive, 763 days
60.0
U0390
64 years, male, NA, stage:T3N1M0, alive, 871 days
59.8
U0972
83 years, female, NA, stage:T1N0M0, alive, 2473 days
59.7
U0377
59 years, female, NA, stage:T3N2M0, alive, 3720 days
59.7
U0165
81 years, female, NA, stage:T2N0M0, alive, 1702 days
59.6
U1147
73 years, male, NA, stage:T3N0M0, dead, 282 days
59.6
U1049
82 years, female, NA, stage:T3N1M0, alive, 1200 days
59.5
U0240
75 years, female, NA, stage:T3N1M0, dead, 800 days
59.5
U1041
81 years, male, NA, stage:T2N0M0, alive, 1108 days
59.4
U2948
74 years, female, NA, stage:T3N1M0, alive, 543 days
59.4
U1369
63 years, male, NA, stage:T3N0M0, dead, 1604 days
59.3
U0149
82 years, female, NA, stage:T3N2M0, alive, 1715 days
59.2
U0317
64 years, female, NA, stage:T3N2M0, alive, 3209 days
58.9
U0384
64 years, male, NA, stage:T2N1M1, alive, 1024 days
58.8
U1208
74 years, female, NA, stage:T1N0M0, alive, 834 days
58.8
U0260
69 years, male, NA, stage:T1N0M1, alive, 2928 days
58.8
U0224
72 years, female, NA, stage:T3N0M0, alive, 2367 days
58.6
U0379
63 years, male, NA, stage:T2N0M0, alive, 1819 days
58.4
U2889
77 years, male, NA, stage:T4N0M0, alive, 623 days
58.4
U0420
56 years, male, NA, stage:T4N1M1, alive, 417 days
58.4
U0095
86 years, male, NA, stage:T4N1M0, dead, 1034 days
58.2
U0348
69 years, female, NA, stage:T3N0M0, alive, 533 days
58.0
U1386
62 years, male, NA, stage:T3N1M0, alive, 1518 days
58.0
U0309
68 years, female, NA, stage:T3N0M0, dead, 1898 days
57.8
U0069
94 years, female, NA, stage:T4N2M0, dead, 135 days
57.8
U0473
33 years, male, NA, stage:T3N1M0, alive, 786 days
57.7
U0256
74 years, male, NA, stage:T3N0M0, alive, 738 days
57.7
U0413
61 years, male, NA, stage:T2N0M0, alive, 1228 days
57.6
U2975
85 years, male, NA, stage:T4N1M0, alive, 514 days
57.5
U1141
71 years, female, NA, stage:T4N1M1, dead, 596 days
57.4
U0148
80 years, male, NA, stage:T3N0M0, alive, 1780 days
57.4
U2792
68 years, male, NA, stage:T2N1M0, alive, 758 days
57.3
U0370
67 years, female, NA, stage:T3N0M0, alive, 1047 days
57.1
U1188
72 years, female, NA, stage:T3N0M0, dead, 967 days
56.9
U1130
78 years, male, NA, stage:T2N1M0, alive, 913 days
56.8
U2947
77 years, female, NA, stage:T3N0M0, alive, 543 days
56.7
U1235
71 years, female, NA, stage:T2N0M0, alive, 1319 days
56.7
U0142
80 years, female, NA, stage:T4N1M0, alive, 2340 days
56.6
U0004
61 years, female, NA, stage:T4N0M0, alive, 3649 days
56.6
U1304
69 years, female, NA, stage:TXNXM0, alive, 1081 days
56.5
U1155
75 years, male, NA, stage:T4N1M0, alive, 1815 days
56.4
U0281
72 years, male, NA, stage:T3N2M0, alive, 933 days
56.3
U0169
82 years, male, NA, stage:T4N2M0, alive, 616 days
56.2
U1366
63 years, male, NA, stage:T3N1M0, alive, 2010 days
56.2
U0970
86 years, female, NA, stage:T4N1M0, alive, 939 days
56.1
U1017
82 years, male, NA, stage:T3N0M0, alive, 615 days
56.0
U0108
84 years, female, NA, stage:T3N0M1, alive, 535 days
56.0
U1252
70 years, female, NA, stage:T4N2M0, alive, 1309 days
55.8
U0124
81 years, female, NA, stage:T1N0M0, alive, 2430 days
55.8
U0218
77 years, female, NA, stage:T3N0M0, alive, 714 days
55.7
U0459
49 years, female, NA, stage:T3N0M0, alive, 966 days
55.7
U0121
86 years, male, NA, stage:T4N2M0, alive, 655 days
55.5
U0467
38 years, female, NA, stage:T3N0M0, alive, 1848 days
55.5
U0383
60 years, male, NA, stage:T3N2M1, dead, 595 days
55.5
U0363
61 years, male, NA, stage:T3N1M0, alive, 3601 days
55.5
U0110
87 years, female, NA, stage:T3N1M1, dead, 878 days
55.4
U0269
69 years, female, NA, stage:T3N0M0, alive, 2530 days
55.3
U3029
84 years, male, NA, stage:T2N0M0, alive, 475 days
54.9
U0099
85 years, female, NA, stage:T3N0M0, dead, 986 days
54.9
U1486
39 years, female, NA, stage:T4N0M0, alive, 1606 days
54.9
U0073
87 years, male, NA, stage:T4N0MX, dead, 318 days
54.8
U0098
84 years, male, NA, stage:T3N0M0, dead, 2473 days
54.8
U0236
72 years, male, NA, stage:T3N1M0, alive, 1842 days
54.8
U3100
89 years, male, NA, stage:T3N1M0, dead, 1608 days
54.7
U0209
74 years, male, NA, stage:T3N1M0, alive, 2109 days
54.6
U0204
78 years, male, NA, stage:T3N0M0, dead, 770 days
54.4
U0156
82 years, female, NA, stage:T4N1M0, alive, 1573 days
54.3
U0189
74 years, female, NA, stage:T3N0M0, dead, 1823 days
54.2
U0135
82 years, female, NA, stage:T3N0M0, alive, 1738 days
54.2
U0091
90 years, male, NA, stage:T3N0M0, alive, 520 days
54.2
U0288
72 years, male, NA, stage:T1N0M0, alive, 1513 days
54.1
U0319
65 years, male, NA, stage:T3N0M0, alive, 2801 days
54.1
U1034
80 years, male, NA, stage:T4N0M0, alive, 1575 days
54.0
U0287
69 years, female, NA, stage:T2N0M0, alive, 1897 days
54.0
U1022
81 years, male, NA, stage:T4N2M0, dead, 61 days
54.0
U0375
66 years, male, NA, stage:T3N0M0, dead, 666 days
54.0
U0133
85 years, female, NA, stage:T3N0M0, alive, 773 days
54.0
U0456
46 years, male, NA, stage:T4N0M0, dead, 2222 days
53.9
U1122
75 years, female, NA, stage:T3N2M0, alive, 1675 days
53.9
U1114
76 years, female, NA, stage:TXNXM1, dead, 473 days
53.7
U0227
72 years, female, NA, stage:T4N2M0, alive, 291 days
53.6
U0126
79 years, male, NA, stage:T3N0M0, dead, 2876 days
53.5
U0368
67 years, male, NA, stage:T2N0M0, alive, 801 days
53.4
U0394
65 years, male, NA, stage:T2N1M0, alive, 969 days
53.4
U1349
63 years, female, NA, stage:T3N1M0, alive, 1899 days
53.3
U0119
81 years, female, NA, stage:T3N0M0, alive, 3259 days
53.3
U0355
67 years, male, NA, stage:T4N1M0, dead, 1038 days
53.3
U0938
86 years, female, NA, stage:T3N0M0, dead, 1231 days
53.2
U0182
79 years, female, NA, stage:T4N1M0, dead, 260 days
53.1
U1069
77 years, female, NA, stage:T3N0M0, dead, 2187 days
53.1
U0177
81 years, female, NA, stage:T3N0M0, alive, 355 days
53.0
U0398
63 years, female, NA, stage:T3N0M0, alive, 721 days
52.9
U3012
66 years, male, NA, stage:T3N0M0, alive, 472 days
52.8
U3018
67 years, male, NA, stage:T4N1M0, alive, 463 days
52.8
U0280
68 years, male, NA, stage:T3N1M1, alive, 2731 days
52.8
U0072
88 years, male, NA, stage:T3N0M0, alive, 2772 days
52.7
U1094
79 years, female, NA, stage:T4N1M0, alive, 1267 days
52.7
U0362
66 years, male, NA, stage:T3N0M0, alive, 1148 days
52.6
U0916
88 years, female, NA, stage:T3N0M0, alive, 1578 days
52.6
U0442
56 years, male, NA, stage:T3N0M0, alive, 619 days
52.5
U0465
43 years, male, NA, stage:T3N0M0, alive, 2383 days
52.5
U1253
68 years, female, NA, stage:T3N0M0, dead, 165 days
52.4
U0933
85 years, male, NA, stage:T3N2M0, dead, 1960 days
52.2
U2842
60 years, female, NA, stage:T4N2M0, alive, 675 days
52.1
U0075
88 years, male, NA, stage:T3N0M0, dead, 3 days
52.0
U0176
76 years, male, NA, stage:T3N1M0, alive, 2600 days
51.8
U3022
77 years, male, NA, stage:T2N0M0, alive, 484 days
51.8
U0939
82 years, male, NA, stage:T3N1M0, alive, 2960 days
51.8
U0117
83 years, female, NA, stage:T2N0M0, dead, 1078 days
51.7
U0440
51 years, female, NA, stage:T4N0M0, dead, 2743 days
51.7
U1158
76 years, female, NA, stage:T3N1M0, alive, 721 days
51.6
U0450
52 years, female, NA, stage:T3N1M0, alive, 763 days
51.5
U0199
78 years, female, NA, stage:T4N2M0, alive, 1372 days
51.5
U3030
77 years, female, NA, stage:T3N0M0, alive, 380 days
51.5
U0333
66 years, female, NA, stage:T3N2M0, dead, 1959 days
51.5
U1120
76 years, male, NA, stage:T4N1M1, alive, 823 days
51.5
U1204
71 years, male, NA, stage:T4N2M0, alive, 2214 days
51.4
U0428
60 years, male, NA, stage:T4N1M1, alive, 1016 days
51.4
U3042
62 years, male, NA, stage:T3N0M0, alive, 324 days
51.4
U0416
61 years, male, NA, stage:T1N1M0, alive, 1228 days
51.2
U0277
72 years, male, NA, stage:T2N1M0, alive, 270 days
51.2
U0462
45 years, female, NA, stage:T4N1M0, alive, 1017 days
51.0
U0352
62 years, female, NA, stage:T4N2M0, dead, 385 days
51.0
U0263
69 years, female, NA, stage:T3N0M1, alive, 362 days
51.0
U1321
65 years, male, NA, stage:T3N1M0, alive, 2578 days
50.9
U0270
70 years, female, NA, stage:T1N0M0, alive, 2187 days
50.9
U0365
68 years, female, NA, stage:T4N1M0, dead, 313 days
50.9
U1347
65 years, female, NA, stage:T3N0M0, alive, 1401 days
50.9
U0389
64 years, female, NA, stage:T3N1M0, dead, 927 days
50.9
U1150
75 years, female, NA, stage:T3N0M0, alive, 15 days
50.8
U0367
61 years, female, NA, stage:T3N1M0, alive, 3075 days
50.7
U0396
59 years, male, NA, stage:T4N2M0, alive, 2243 days
50.7
U0382
61 years, female, NA, stage:T3N0M0, alive, 2550 days
50.7
U2999
79 years, female, NA, stage:T2N0M0, alive, 581 days
50.7
U1258
70 years, male, NA, stage:T3N1M0, alive, 1373 days
50.7
U0436
59 years, male, NA, stage:T4N1M1, alive, 960 days
50.6
U2964
84 years, male, NA, stage:T3N1M0, alive, 637 days
50.5
U0429
58 years, female, NA, stage:T3N0M1, alive, 1099 days
50.5
U1344
65 years, female, NA, stage:T3N1M0, alive, 1450 days
50.5
U3043
68 years, female, NA, stage:T3N2M0, alive, 287 days
50.4
U1327
66 years, female, NA, stage:T3N0M0, alive, 1613 days
50.4
U0125
86 years, female, NA, stage:T1N0M0, dead, 668 days
50.3
U2819
86 years, female, NA, stage:T3N0M0, alive, 708 days
50.3
U0107
82 years, male, NA, stage:T3N0M0, dead, 2354 days
50.3
U1436
56 years, female, NA, stage:T3N0M0, alive, 1745 days
50.3
U0131
81 years, female, NA, stage:T4N2M1, alive, 238 days
50.0
U0066
93 years, male, NA, stage:T3N0M0, dead, 2486 days
50.0
U0306
71 years, male, NA, stage:T3N1M0, dead, 717 days
49.9
U0397
62 years, male, NA, stage:T4N0M0, alive, 1663 days
49.6
U3034
64 years, female, NA, stage:T3N1M0, alive, 443 days
49.6
U0105
82 years, female, NA, stage:T2N0M0, dead, 2158 days
49.6
U0318
71 years, male, NA, stage:T3N0M0, alive, 762 days
49.5
U0123
83 years, male, NA, stage:T3N0M0, dead, 1880 days
49.5
U0991
83 years, male, NA, stage:T4N2M0, dead, 534 days
49.3
U3000
69 years, female, NA, stage:T3N0M0, alive, 584 days
49.3
U1392
61 years, male, NA, stage:T3N0M0, alive, 1513 days
49.1
U0308
72 years, male, NA, stage:T4N1M0, alive, 1075 days
49.1
U0109
82 years, female, NA, stage:T4N2M1, alive, 144 days
49.0
U1220
70 years, male, NA, stage:T3N2M0, dead, 1953 days
49.0
U0357
64 years, female, NA, stage:T3N0M0, alive, 2285 days
48.9
U1212
74 years, female, NA, stage:T2N0M0, alive, 69 days
48.8
U0303
67 years, female, NA, stage:T3N0M0, alive, 2847 days
48.7
U0067
92 years, female, NA, stage:T3N0M0, alive, 2180 days
48.7
U3024
76 years, female, NA, stage:T3N0M0, alive, 463 days
48.7
U0161
78 years, male, NA, stage:T4N2M1, alive, 42 days
48.7
U2848
67 years, female, NA, stage:T4N2M0, alive, 669 days
48.7
U0273
68 years, male, NA, stage:T2N1M0, alive, 2641 days
48.6
U0129
82 years, male, NA, stage:T4N0M0, dead, 1265 days
48.5
U0955
83 years, female, NA, stage:T3N0M0, alive, 2170 days
48.5
U1067
79 years, male, NA, stage:T3N0M0, alive, 1570 days
48.5
U0249
75 years, female, NA, stage:T4N2M0, dead, 874 days
48.4
U0207
73 years, female, NA, stage:T3N0M0, dead, 2593 days
48.3
U0373
64 years, female, NA, stage:T3N0M0, alive, 1822 days
48.2
U1257
71 years, male, NA, stage:T3N0M0, alive, 833 days
48.1
U0113
88 years, male, NA, stage:T4N2M0, alive, 1102 days
48.1
U1338
67 years, female, NA, stage:T4N1M0, dead, 716 days
48.0
U1472
47 years, female, NA, stage:T3N1M0, alive, 1316 days
48.0
U0381
60 years, male, NA, stage:T3N1M0, dead, 71 days
48.0
U0172
78 years, male, NA, stage:T4N0M0, dead, 678 days
47.8
U1483
43 years, female, NA, stage:T3N0M0, alive, 1094 days
47.8
U3038
82 years, male, NA, stage:T3N0M0, alive, 328 days
47.7
U0361
63 years, male, NA, stage:T3N0M0, alive, 686 days
47.6
U0183
74 years, male, NA, stage:T3N1M1, dead, 2957 days
47.6
U0376
66 years, male, NA, stage:T2N1M0, alive, 965 days
47.4
U1474
45 years, female, NA, stage:T1N0MX, alive, 2012 days
47.4
U1086
73 years, female, NA, stage:T1N0M0, alive, 2907 days
47.2
U0332
66 years, female, NA, stage:T3N0M0, alive, 2101 days
47.2
U0426
59 years, male, NA, stage:T3N0M0, dead, 976 days
47.2
U0445
51 years, female, NA, stage:T3N0M0, alive, 1851 days
47.2
U0297
67 years, female, NA, stage:T3N2M0, alive, 1196 days
47.1
U1446
53 years, female, NA, stage:T3N0M0, alive, 2314 days
47.0
U0336
68 years, female, NA, stage:T3N0M0, alive, 1100 days
47.0
U3050
61 years, female, NA, stage:T3N0M0, alive, 407 days
47.0
U1099
77 years, female, NA, stage:T3N0M0, alive, 2068 days
46.9
U0152
82 years, male, NA, stage:T3N1M0, alive, 989 days
46.9
U0102
87 years, female, NA, stage:T4N2M0, dead, 670 days
46.9
U0090
85 years, female, NA, stage:T3N0M0, dead, 1258 days
46.8
U1145
74 years, female, NA, stage:T3N0M0, dead, 445 days
46.8
U0307
65 years, male, NA, stage:T3N0M0, alive, 2921 days
46.8
U3025
68 years, male, NA, stage:T4N2M1, alive, 377 days
46.6
U0302
73 years, male, NA, stage:T1N0M0, alive, 892 days
46.6
U0266
70 years, female, NA, stage:T3N1M0, dead, 2221 days
46.5
U0449
50 years, female, NA, stage:T3N0M0, alive, 1851 days
46.5
U0274
70 years, male, NA, stage:T3N0M0, dead, 1570 days
46.5
U0966
84 years, male, NA, stage:T4N0M0, dead, 1513 days
46.2
U0960
86 years, male, NA, stage:T3N0M0, alive, 1009 days
46.1
U2953
55 years, female, NA, stage:T4aN0M0, alive, 541 days
46.0
U0094
89 years, female, NA, stage:T3N2M0, alive, 741 days
45.9
U0103
88 years, female, NA, stage:T3N1M0, alive, 1197 days
45.9
U1246
70 years, female, NA, stage:T3N0M0, alive, 1441 days
45.9
U0166
82 years, female, NA, stage:T3N0M0, alive, 763 days
45.9
U0313
70 years, male, NA, stage:T4N1M0, dead, 1142 days
45.8
U0170
77 years, male, NA, stage:T4N1M0, dead, 832 days
45.7
U0247
70 years, female, NA, stage:T3N1M0, alive, 2538 days
45.6
U0143
80 years, male, NA, stage:T3N2M0, alive, 2313 days
45.5
U1241
70 years, male, NA, stage:T3N1M0, dead, 49 days
45.4
U0314
67 years, female, NA, stage:T1N0M0, dead, 2436 days
45.4
U2928
52 years, male, NA, stage:T2N0M0, alive, 563 days
45.2
U1396
62 years, female, NA, stage:T4N0M0, alive, 1168 days
45.2
U0085
88 years, male, NA, stage:T4N1M0, dead, 1698 days
45.1
U1103
76 years, female, NA, stage:T4N2M0, alive, 975 days
45.1
U1317
68 years, male, NA, stage:T4N1M0, alive, 965 days
45.0
U0222
72 years, female, NA, stage:T3N2M1, alive, 1779 days
44.6
U0089
85 years, female, NA, stage:T1NXM0, dead, 2365 days
44.6
U0146
79 years, female, NA, stage:T3N2M0, dead, 733 days
44.6
U0385
65 years, male, NA, stage:T3N0M0, alive, 902 days
44.6
U1201
72 years, male, NA, stage:T3N2M0, alive, 1484 days
44.6
U1031
80 years, male, NA, stage:T1N1M0, alive, 1625 days
44.4
U1292
69 years, female, NA, stage:T4N1M0, alive, 1147 days
44.4
U0350
68 years, female, NA, stage:T4N0M0, alive, 770 days
44.3
U0344
69 years, male, NA, stage:T2N1M0, dead, 818 days
44.3
U0171
78 years, female, NA, stage:T3N1M0, dead, 1920 days
44.2
U0340
69 years, female, NA, stage:T4N2M1, dead, 438 days
44.2
U0448
46 years, male, NA, stage:T3N2M0, alive, 3615 days
44.1
U1184
70 years, male, NA, stage:T4N1M0, alive, 290 days
44.0
U0338
68 years, female, NA, stage:T3N0M0, alive, 1016 days
43.9
U0345
65 years, female, NA, stage:T3N0M0, alive, 2127 days
43.7
U3005
74 years, male, NA, stage:T3N0M0, alive, 478 days
43.7
U0321
70 years, female, NA, stage:T3N0M0, alive, 1029 days
43.7
U0208
76 years, female, NA, stage:T3N1M0, dead, 1233 days
43.7
U0386
60 years, female, NA, stage:T4N1M1, alive, 2592 days
43.6
U1111
76 years, female, NA, stage:T3N0M0, dead, 1631 days
43.5
U1213
73 years, female, NA, stage:T2N0M0, alive, 560 days
43.4
U0326
64 years, female, NA, stage:T3N0M0, alive, 3178 days
43.4
U0358
64 years, female, NA, stage:T4N1M0, alive, 2290 days
43.3
U0349
63 years, male, NA, stage:T3N1M0, alive, 2682 days
43.2
U0254
75 years, female, NA, stage:T3N1M0, alive, 659 days
43.2
U0290
72 years, male, NA, stage:T4N2M0, dead, 593 days
43.2
U0411
59 years, female, NA, stage:T3N1M0, alive, 1868 days
43.1
U0245
71 years, female, NA, stage:T3N1M0, dead, 564 days
43.0
U1127
71 years, female, NA, stage:T3N0M0, alive, 3465 days
43.0
U0460
43 years, female, NA, stage:T3N0M0, dead, 2069 days
43.0
U0100
85 years, female, NA, stage:T3N0M0, dead, 1920 days
42.9
U1250
70 years, male, NA, stage:T2N0M0, alive, 597 days
42.8
U0433
58 years, male, NA, stage:T4N1M1, dead, 440 days
42.8
U0421
60 years, male, NA, stage:T3N1M0, alive, 674 days
42.8
U1267
65 years, male, NA, stage:T3N1M0, dead, 2869 days
42.7
U0101
84 years, male, NA, stage:T3N1M1, alive, 1878 days
42.7
U0285
69 years, female, NA, stage:T3N0M0, alive, 2165 days
42.6
U1160
74 years, male, NA, stage:T3N1M0, alive, 1557 days
42.5
U0180
74 years, male, NA, stage:T3N0M1, dead, 965 days
42.5
U1062
78 years, female, NA, stage:T4N0M0, alive, 1689 days
42.4
U0092
84 years, male, NA, stage:T3N0M0, alive, 2779 days
42.3
U0229
70 years, female, NA, stage:TXN2M1, dead, 2115 days
42.2
U0235
75 years, female, NA, stage:T3N0M0, alive, 1327 days
42.2
U1065
75 years, female, NA, stage:T3N2M0, alive, 2954 days
42.1
U0369
66 years, female, NA, stage:T3N0M0, dead, 1095 days
42.1
U0312
65 years, female, NA, stage:T4N2M1, alive, 499 days
42.0
U1037
80 years, male, NA, stage:T4N0M0, alive, 1658 days
42.0
U0259
68 years, female, NA, stage:T4N2M0, alive, 76 days
41.9
U0335
65 years, female, NA, stage:T3N1M0, alive, 2464 days
41.9
U0315
65 years, female, NA, stage:T2N0M0, alive, 1973 days
41.9
U0268
67 years, male, NA, stage:T3N0M0, alive, 2978 days
41.9
U1343
62 years, female, NA, stage:T4N2M0, alive, 3178 days
41.8
U0106
82 years, female, NA, stage:T3N1M0, dead, 653 days
41.8
U0233
71 years, female, NA, stage:T3N1M0, alive, 975 days
41.8
U1044
76 years, male, NA, stage:T4N0M0, alive, 3146 days
41.8
U0392
64 years, male, NA, stage:T3N2M0, alive, 489 days
41.8
U0244
69 years, female, NA, stage:T3N1M0, alive, 3184 days
41.7
U0087
87 years, female, NA, stage:T3N2M0, dead, 337 days
41.6
U0134
82 years, male, NA, stage:T3N0M0, alive, 2009 days
41.6
U0942
88 years, male, NA, stage:T3N0M0, alive, 665 days
41.6
U0403
60 years, male, NA, stage:T3N1M1, dead, 1809 days
41.4
U0211
76 years, female, NA, stage:T3N1M0, alive, 1236 days
41.4
U0590
75 years, female, NA, stage:T3N0M0, alive, 661 days
41.0
U1007
82 years, male, NA, stage:T3N0M0, alive, 1333 days
41.0
U1046
78 years, female, NA, stage:T4N2M1, dead, 697 days
41.0
U0401
60 years, male, NA, stage:T4N1M0, alive, 1715 days
40.9
U0196
75 years, male, NA, stage:T3N0M0, alive, 2086 days
40.9
U0347
68 years, female, NA, stage:T4N1M1, alive, 628 days
40.9
U0295
67 years, male, NA, stage:T3N0M0, dead, 2572 days
40.6
U0178
76 years, female, NA, stage:T3N1M0, dead, 2096 days
40.6
U1454
54 years, female, NA, stage:T3N0M0, alive, 393 days
40.5
U0084
86 years, male, NA, stage:T3N0M0, dead, 1662 days
40.5
U0145
81 years, male, NA, stage:T3N1M1, alive, 623 days
40.3
U0300
71 years, male, NA, stage:T2N0M0, alive, 974 days
40.3
U1018
81 years, male, NA, stage:T4N1M1, dead, 1693 days
40.2
U1346
66 years, female, NA, stage:T3N0M0, alive, 1137 days
40.1
U0083
88 years, male, NA, stage:T4N0M0, dead, 731 days
39.9
U0154
83 years, male, NA, stage:T3N0M0, alive, 820 days
39.8
U0175
77 years, male, NA, stage:T3N2M0, alive, 1875 days
39.7
U0223
71 years, male, NA, stage:T4N1M0, alive, 1812 days
39.5
U0153
80 years, female, NA, stage:T3N0M0, dead, 1718 days
39.4
U1473
46 years, female, NA, stage:T3N0M0, alive, 1553 days
39.3
U2902
86 years, female, NA, stage:T2N0M0, alive, 596 days
39.2
U0455
47 years, female, NA, stage:T3N2M0, alive, 2445 days
39.1
U1071
78 years, female, NA, stage:T4N0M1, alive, 1514 days
39.1
U0908
89 years, female, NA, stage:T3N0M1, dead, 40 days
39.1
U1240
70 years, male, NA, stage:T4N0M0, alive, 765 days
39.0
U0320
66 years, female, NA, stage:T4N2M1, alive, 188 days
38.9
U0443
54 years, male, NA, stage:T3N0M0, alive, 1677 days
38.6
U0289
66 years, female, NA, stage:T3N0M0, alive, 3511 days
38.5
U0424
56 years, male, NA, stage:T3N0M0, alive, 2192 days
38.5
U1073
79 years, female, NA, stage:T3N1M0, alive, 1359 days
38.3
U1013
82 years, female, NA, stage:T2N1M0, alive, 1439 days
38.1
U1107
80 years, male, NA, stage:T3N0M0, alive, 329 days
37.9
U0246
74 years, female, NA, stage:T4N0M0, dead, 1192 days
37.9
U0158
76 years, male, NA, stage:T1N0M0, dead, 3101 days
37.7
U1332
65 years, male, NA, stage:T3N0M0, alive, 1672 days
37.7
U0070
89 years, male, NA, stage:T1N0M0, dead, 1319 days
37.3
U0151
80 years, female, NA, stage:T3N0M0, alive, 2014 days
37.1
U0187
77 years, male, NA, stage:T3N2M0, alive, 1632 days
37.1
U1301
66 years, female, NA, stage:T4N2M0, dead, 877 days
37.0
U1104
78 years, female, NA, stage:T4N0M0, alive, 1109 days
37.0
U1072
80 years, male, NA, stage:T1N0M0, alive, 1446 days
36.6
U0210
75 years, male, NA, stage:T3N0M0, dead, 1800 days
36.5
U0202
73 years, male, NA, stage:T3N0M0, dead, 2670 days
36.3
U0882
93 years, male, NA, stage:T3N0M0, alive, 1675 days
36.2
U0354
69 years, male, NA, stage:T3N1M0, alive, 430 days
35.9
U0257
69 years, male, NA, stage:T3N1M0, dead, 2508 days
35.8
U1183
73 years, male, NA, stage:T4N2M0, alive, 959 days
34.6
U0193
76 years, male, NA, stage:T3N1M0, dead, 876 days
34.4
U1059
77 years, male, NA, stage:T3N1M0, alive, 2790 days
34.4
U0453
46 years, male, NA, stage:T3N0M0, alive, 2859 days
34.1
U0081
87 years, male, NA, stage:T3N2M0, dead, 248 days
33.8
U0984
84 years, female, NA, stage:T4N0M0, alive, 1287 days
33.7
U1075
78 years, female, NA, stage:T3N0M0, alive, 1290 days
33.7
U0200
73 years, female, NA, stage:T3N0M0, alive, 2614 days
33.4
U0316
68 years, male, NA, stage:T3N2M0, alive, 2012 days
33.3
U0408
56 years, female, NA, stage:T4N0M0, dead, 2100 days
33.3
U0136
79 years, female, NA, stage:T3N0M0, dead, 2795 days
33.3
U0993
83 years, male, NA, stage:T4N2M0, alive, 1267 days
33.3
U0115
84 years, female, NA, stage:T3N0M0, dead, 1738 days
33.2
U0400
62 years, male, NA, stage:T4N0M0, dead, 1073 days
33.2
U0262
69 years, female, NA, stage:T2N0M0, alive, 2534 days
32.9
U0471
38 years, female, NA, stage:T3N1M0, alive, 1673 days
32.9
U0934
87 years, female, NA, stage:T3N0M0, alive, 1185 days
32.4
U1228
71 years, male, NA, stage:T3N0M0, alive, 1333 days
32.2
U0167
79 years, male, NA, stage:T3N1M0, alive, 1820 days
31.9
U0441
50 years, female, NA, stage:T2N1M0, alive, 2738 days
31.6
U0225
77 years, male, NA, stage:T3N1M0, alive, 581 days
30.4
U0252
70 years, male, NA, stage:T3N1M0, dead, 1761 days
30.1
U0141
81 years, male, NA, stage:T3N2M0, alive, 2079 days
28.3
U0248
72 years, male, NA, stage:T3N0M0, alive, 1870 days
27.6
U0234
75 years, male, NA, stage:T1N1M0, alive, 990 days
26.1
U0327
70 years, male, NA, stage:T4N0M0, alive, 833 days
25.2
U0214
72 years, male, NA, stage:T4N1M1, alive, 788 days
25.1
U0342
68 years, male, NA, stage:T4N2M0, alive, 305 days
24.2
U1384
62 years, male, NA, stage:T4N1M0, alive, 1319 days
1.8
U0074
89 years, female, NA, stage:T3N0M0, dead, 1438 days
The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.
The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".
Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.
Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.
& Survival analysisi
Kaplan-Meier plots summarize results from analysis of correlation between mRNA expression level and patient survival. Patients were divided based on level of expression into one of the two groups "low" (under cut off) or "high" (over cut off). X-axis shows time for survival (years) and y-axis shows the probability of survival, where 1.0 corresponds to 100 percent.
MARK2 is not prognostic in Rectum Adenocarcinoma (TCGA)
Stage:
Survival analysis
Current cut offi
Current cut-off shows the cut-off (FPKM) currently selected. It may be changed manually. When the current cut-off is changed, the vertical dashed line indicating cut-off, the interactive survival scatter plot and the Kaplan-Meier curve will be automatically adjusted to show results accordingly.
:
Best expression cut offi
Based on the FPKM value of each gene, patients were classified into two groups and association between prognosis (survival) and gene expression (FPKM) was examined. The best expression cut-off refers the FPKM value that yields maximal difference with regard to survival between the two groups at the lowest log-rank P-value. Best expression cut-off was selected based on survival analysis .
When clicking on this number, the vertical dashed line indicating cut-off, the interactive survival plot, and the Kaplan-Meier curve will be adjusted to show results based on the best expression cut-off.
Median expression refers to the median FPKM value calculated based on the gene expression (FPKM) data from all patients in this dataset. When clicking on this number, the vertical dashed line indicating cut-off, the interactive survival plot, and the Kaplan-Meier curve will be adjusted to show results based on the median expression.
Median follow up time refers to the median time (years) after diagnosis with this type of cancer, based on clinical data from all patients in this dataset.
: N/A
P scorei
Log-rank P value for Kaplan-Meier plot showing results from analysis of correlation between mRNA expression level and patient survival.
N/A
5-year survival highi
5-year survival for patients with higher expression than the expression cutoff.
For melanoma and glioma, 3-year survival is shown.
N/A
5-year survival lowi
5-year survival for patients with lower expression than the expression cutoff.
For melanoma and glioma, 3-year survival is shown.
N/A
TCGA RNA samplesi
RNA-seq data is reported as average FPKM (number Fragments Per Kilobase of exon per Million reads), generated by the The Cancer Genome Atlas (TCGA) .
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. FPKM values of the individual samples are presented next to the box plot.
Average TPM
22.8
Number of samples
88
Samples
Sample
Description
TPM
TCGA-EI-6885-01A
57 years, female, white, stage:Stage IV, alive, 415 days
40.9
TCGA-AG-4021-01A
84 years, female, stage:Stage IV, dead, 121 days
40.7
TCGA-EI-6882-01A
59 years, male, white, stage:Stage IIA, alive, 262 days
38.9
TCGA-EI-6508-01A
48 years, female, white, stage:Stage IIIB, alive, 636 days
38.0
TCGA-CI-6620-01A
41 years, female, white, stage:Stage IVA, alive, 1009 days
35.4
TCGA-AG-3732-01A
78 years, female, stage:Stage I, alive, 1003 days
35.3
TCGA-EI-7004-01A
37 years, female, white, stage:'--, alive, 257 days
35.0
TCGA-EI-6884-01A
71 years, male, white, stage:Stage IIIA, alive, 328 days
34.3
TCGA-DC-6157-01A
48 years, male, black or african american, stage:Stage I, alive, 1581 days
34.2
TCGA-AH-6897-01A
48 years, male, white, stage:Stage I, alive, 804 days
34.0
TCGA-EI-6506-01A
78 years, female, white, stage:Stage IIA, alive, 625 days
32.5
TCGA-CL-5917-01A
71 years, female, white, stage:Stage IIIC, alive, 2376 days
30.9
TCGA-EI-6512-01A
64 years, female, white, stage:Stage IIIB, alive, 538 days
30.6
TCGA-AG-3731-01A
65 years, male, stage:Stage IV, alive, 1126 days
30.5
TCGA-EI-6513-01A
59 years, male, white, stage:Stage IIIB, alive, 497 days
30.0
TCGA-F5-6464-01A
77 years, female, white, stage:Stage IIIC, dead, 303 days
29.5
TCGA-DC-6156-01A
62 years, male, white, stage:Stage IVA, alive, 943 days
29.5
TCGA-EF-5830-01A
54 years, male, white, stage:Stage IIB, alive, 106 days
28.4
TCGA-F5-6702-01A
71 years, male, white, stage:Stage IVA, dead, 869 days
28.0
TCGA-F5-6571-01A
62 years, female, white, stage:Stage IIA, alive, 1288 days
28.0
TCGA-F5-6465-01A
64 years, female, white, stage:Stage IIA, alive, 1506 days
27.2
TCGA-DC-6154-01A
57 years, female, white, stage:Stage IVA, alive, 365 days
26.9
TCGA-DC-6683-01A
43 years, male, white, stage:Stage IIIB, alive, 762 days
26.9
TCGA-F5-6861-01A
60 years, female, white, stage:Stage IIA, alive, 1160 days
26.4
TCGA-EI-7002-01A
58 years, male, white, stage:Stage IV, alive, 364 days
26.3
TCGA-AF-6655-01A
66 years, male, white, stage:Stage IIIA, alive, 609 days
26.2
TCGA-CI-6622-01A
74 years, male, white, stage:Stage IIB, alive, 1362 days
26.1
TCGA-DC-6681-01A
70 years, female, white, stage:Stage IVA, alive, 790 days
26.1
TCGA-EI-6507-01A
60 years, male, white, stage:Stage IIA, alive, 607 days
26.0
TCGA-AG-3592-01A
68 years, male, stage:Stage IIA, alive, 1035 days
25.9
TCGA-AH-6547-01A
79 years, female, white, stage:'--, dead, 76 days
25.8
TCGA-AF-A56N-01A
47 years, female, black or african american, stage:Stage IIA, alive, 360 days
25.7
TCGA-F5-6863-01A
71 years, female, white, stage:Stage IIIB, dead, 361 days
25.7
TCGA-EI-6511-01A
52 years, male, white, stage:Stage IIIB, alive, 482 days
25.6
TCGA-AG-3742-01A
85 years, female, stage:Stage I, alive, 30 days
25.6
TCGA-F5-6813-01A
70 years, male, white, stage:Stage IIIC, dead, 598 days
25.4
TCGA-DC-6158-01A
70 years, male, white, stage:Stage I, dead, 334 days
25.4
TCGA-CI-6621-01A
63 years, male, white, stage:Stage IIIB, alive, 419 days
25.4
TCGA-EI-6881-01A
60 years, male, white, stage:Stage IIIA, alive, 499 days
25.4
TCGA-AH-6644-01A
73 years, male, white, stage:'--, alive, 838 days
25.1
TCGA-AG-3902-01A
61 years, male, stage:Stage IIA, alive, 974 days
24.8
TCGA-F5-6814-01A
57 years, male, white, stage:Stage IIA, alive, 1131 days
24.8
TCGA-AF-3911-01A
48 years, male, white, stage:Stage IIIC, alive, 1148 days
23.9
TCGA-AG-4022-01A
59 years, female, stage:Stage II, alive, 1400 days
23.2
TCGA-EI-6883-01A
63 years, male, white, stage:Stage IIC, alive, 350 days
23.0
TCGA-G5-6235-01A
72 years, male, white, stage:Stage IIIB, alive, 1696 days
22.7
TCGA-AH-6549-01A
66 years, male, white, stage:'--, alive, 532 days
22.6
TCGA-AH-6903-01A
46 years, male, white, stage:Stage IIIB, alive, 592 days
22.5
TCGA-DC-4749-01A
57 years, male, white, stage:Stage I, alive, 762 days
22.0
TCGA-F5-6811-01A
72 years, female, white, stage:Stage IIA, alive, 979 days
21.7
TCGA-DC-6160-01A
68 years, male, white, stage:Stage I, alive, 1339 days
21.2
TCGA-F5-6864-01A
74 years, female, white, stage:Stage IIIB, alive, 379 days
20.6
TCGA-EI-6917-01A
33 years, male, white, stage:Stage IIIA, alive, 531 days
20.6
TCGA-EI-6514-01A
59 years, female, white, stage:Stage IIA, alive, 496 days
20.4
TCGA-G5-6572-01A
56 years, male, white, stage:'--, dead, 1432 days
20.4
TCGA-AF-A56L-01A
48 years, female, black or african american, stage:Stage IIIC, alive, 2007 days
20.3
TCGA-DY-A1DC-01A
72 years, female, white, stage:Stage IIA, dead, 1258 days
19.8
TCGA-DY-A1DE-01A
56 years, female, white, stage:Stage IIA, alive, 3932 days
19.3
TCGA-AH-6643-01A
50 years, male, white, stage:Stage IIIC, dead, 1314 days
19.2
TCGA-AF-2693-01A
75 years, male, white, stage:Stage I, alive, 1155 days
19.2
TCGA-EI-6510-01A
77 years, female, white, stage:'--, alive, 556 days
19.1
TCGA-G5-6641-01A
67 years, male, white, stage:Stage IIIA, alive, 804 days
19.0
TCGA-DC-5869-01A
62 years, female, black or african american, stage:Stage IIIB, alive, 943 days
18.7
TCGA-G5-6233-01A
74 years, male, white, stage:'--, dead, 556 days
17.9
TCGA-AF-6136-01A
72 years, female, white, stage:Stage IIIB, alive, 741 days
17.7
TCGA-AF-2687-01A
57 years, male, white, stage:Stage IIIC, alive, 1427 days
17.6
TCGA-AF-A56K-01A
56 years, male, black or african american, stage:Stage IIA, alive, 2635 days
17.5
TCGA-CL-4957-01A
79 years, female, stage:'--, dead, 425 days
16.9
TCGA-DY-A0XA-01A
57 years, female, white, stage:Stage IIA, alive, 3846 days
16.3
TCGA-EF-5831-01A
72 years, male, white, stage:Stage IIA, alive, 127 days
16.3
TCGA-AH-6544-01A
60 years, male, white, stage:'--, alive, 1173 days
15.7
TCGA-AF-4110-01A
77 years, male, white, stage:Stage IVA, alive, 912 days
15.7
TCGA-DC-6682-01A
57 years, male, white, stage:Stage IIA, alive, 762 days
15.5
TCGA-DC-4745-01A
49 years, female, white, stage:Stage IIIB, alive, 639 days
15.2
TCGA-F5-6812-01A
67 years, male, white, stage:Stage IIA, alive, 1110 days
14.1
TCGA-AF-5654-01A
73 years, female, white, stage:Stage I, dead, 512 days
13.8
TCGA-EI-6509-01A
53 years, male, white, stage:Stage IIIC, alive, 517 days
13.1
TCGA-AF-2690-01A
76 years, female, white, stage:Stage IIIC, dead, 524 days
11.9
TCGA-DY-A1DG-01A
75 years, male, white, stage:Stage IVA, dead, 1566 days
11.8
TCGA-DT-5265-01A
51 years, male, asian, stage:Stage II, alive, 384 days
11.5
TCGA-DY-A1DD-01A
77 years, female, white, stage:Stage IIIB, dead, 1741 days
11.4
TCGA-AF-6672-01A
43 years, male, white, stage:Stage IV, alive, 748 days
11.4
TCGA-BM-6198-01A
73 years, male, white, stage:Stage IIIB, alive, 646 days
11.1
TCGA-DC-6155-01A
31 years, female, white, stage:Stage IIIA, alive, 425 days
9.6
TCGA-DC-5337-01A
69 years, male, white, stage:Stage I, alive, 792 days
9.2
TCGA-DY-A1DF-01A
73 years, female, white, stage:Stage IIIC, dead, 734 days
9.0
TCGA-AG-3591-01A
66 years, female, stage:Stage IIA, alive, 1035 days
8.8
TCGA-DY-A1H8-01A
77 years, female, white, stage:Stage IIIA, dead, 992 days
The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.
The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".
Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.
Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.
& Survival analysisi
Kaplan-Meier plots summarize results from analysis of correlation between mRNA expression level and patient survival. Patients were divided based on level of expression into one of the two groups "low" (under cut off) or "high" (over cut off). X-axis shows time for survival (years) and y-axis shows the probability of survival, where 1.0 corresponds to 100 percent.
MARK2 is not prognostic in Rectum Adenocarcinoma (validation)
Stage:
Survival analysis
Current cut offi
Current cut-off shows the cut-off (FPKM) currently selected. It may be changed manually. When the current cut-off is changed, the vertical dashed line indicating cut-off, the interactive survival scatter plot and the Kaplan-Meier curve will be automatically adjusted to show results accordingly.
:
Best expression cut offi
Based on the FPKM value of each gene, patients were classified into two groups and association between prognosis (survival) and gene expression (FPKM) was examined. The best expression cut-off refers the FPKM value that yields maximal difference with regard to survival between the two groups at the lowest log-rank P-value. Best expression cut-off was selected based on survival analysis .
When clicking on this number, the vertical dashed line indicating cut-off, the interactive survival plot, and the Kaplan-Meier curve will be adjusted to show results based on the best expression cut-off.
Median expression refers to the median FPKM value calculated based on the gene expression (FPKM) data from all patients in this dataset. When clicking on this number, the vertical dashed line indicating cut-off, the interactive survival plot, and the Kaplan-Meier curve will be adjusted to show results based on the median expression.
Median follow up time refers to the median time (years) after diagnosis with this type of cancer, based on clinical data from all patients in this dataset.
: N/A
P scorei
Log-rank P value for Kaplan-Meier plot showing results from analysis of correlation between mRNA expression level and patient survival.
N/A
5-year survival highi
5-year survival for patients with higher expression than the expression cutoff.
For melanoma and glioma, 3-year survival is shown.
N/A
5-year survival lowi
5-year survival for patients with lower expression than the expression cutoff.
For melanoma and glioma, 3-year survival is shown.
N/A
TCGA RNA samplesi
RNA-seq data is reported as average FPKM (number Fragments Per Kilobase of exon per Million reads), generated by the The Cancer Genome Atlas (TCGA) .
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. FPKM values of the individual samples are presented next to the box plot.
Average TPM
47.0
Number of samples
207
Samples
Sample
Description
TPM
U2836
87 years, male, NA, stage:T3N0M0, alive, 322 days
75.9
U2955
50 years, male, NA, stage:T3N1M0, alive, 181 days
73.3
U2761
74 years, female, NA, stage:T3N1M0, alive, 447 days
73.0
U0656
68 years, male, NA, stage:T3N2M0, alive, 1150 days
68.3
U2994
70 years, female, NA, stage:T4N1M0, alive, 132 days
67.6
U0232
71 years, female, NA, stage:T2N0M0, dead, 994 days
67.4
U0637
56 years, male, NA, stage:T3N1M0, alive, 1997 days
66.5
U0695
85 years, male, NA, stage:T3N0M0, alive, 566 days
66.4
U0230
70 years, female, NA, stage:T1N1M0, alive, 3152 days
66.1
U0652
76 years, male, NA, stage:T3N0M0, alive, 1319 days
65.5
U0140
80 years, male, NA, stage:T3N2M0, alive, 2655 days
64.8
U0343
69 years, female, NA, stage:T2N0M0, alive, 701 days
63.7
U0852
36 years, male, NA, stage:T3N2M1, alive, 1651 days
63.7
U2991
77 years, female, NA, stage:T1N0M0, alive, 135 days
62.7
U0654
72 years, male, NA, stage:T3N2M0, alive, 1220 days
62.2
U0086
86 years, female, NA, stage:T3N1M0, dead, 594 days
61.8
U0592
90 years, female, NA, stage:T2N0M0, dead, 670 days
60.9
U0803
68 years, female, NA, stage:T3N1M1, dead, 495 days
60.4
U3023
63 years, female, NA, stage:T2N0M0, alive, 404 days
59.9
U0849
81 years, female, NA, stage:T4N0M1, dead, 267 days
59.8
U0296
67 years, male, NA, stage:T3N0M0, alive, 2610 days
59.2
U0502
65 years, male, NA, stage:T4N1M0, alive, 1065 days
59.1
U0030
82 years, female, NA, stage:T2N0M0, dead, 987 days
59.1
U0238
73 years, male, NA, stage:T3N0M0, dead, 868 days
59.0
U0001
69 years, female, NA, stage:T3N0M0, alive, 3188 days
58.8
U0422
56 years, female, NA, stage:T3N2M1, dead, 1710 days
58.6
U0538
73 years, female, NA, stage:T3N1M0, alive, 1308 days
58.2
U2972
91 years, male, NA, stage:T3N0M0, alive, 161 days
58.2
U2764
65 years, male, NA, stage:T3N2M0, alive, 440 days
58.1
U0494
73 years, male, NA, stage:T4N2M0, alive, 1290 days
58.1
U0651
70 years, male, NA, stage:T3N0M0, alive, 1354 days
57.8
U0391
64 years, female, NA, stage:T3N0M0, alive, 1179 days
57.3
U0809
85 years, female, NA, stage:T3N1M1, dead, 275 days
57.1
U0305
66 years, male, NA, stage:T3N1M0, alive, 2676 days
56.7
U0645
60 years, male, NA, stage:T3N0M0, alive, 1567 days
56.7
U0415
56 years, male, NA, stage:T3N1M0, alive, 2526 days
56.6
U2834
70 years, male, NA, stage:T3N1M0, alive, 323 days
56.5
U0173
77 years, male, NA, stage:T2N0M0, dead, 2375 days
56.1
U0282
70 years, male, NA, stage:T3N2M0, dead, 1869 days
56.0
U0118
81 years, female, NA, stage:T3N2M0, dead, 350 days
55.7
U2960
52 years, male, NA, stage:T3N1M0, alive, 176 days
55.7
U0601
75 years, female, NA, stage:T4N1M0, alive, 1368 days
55.5
U0407
59 years, male, NA, stage:T3N1M0, dead, 2027 days
55.5
U0454
46 years, male, NA, stage:T3N1M0, alive, 2997 days
55.3
U0776
62 years, male, NA, stage:T4N2M0, alive, 1702 days
55.2
U0641
61 years, female, NA, stage:T3N0M0, dead, 1626 days
54.8
U0251
71 years, male, NA, stage:T2N0M0, alive, 1906 days
54.3
U0663
78 years, female, NA, stage:T3N1M0, alive, 762 days
54.0
U0096
88 years, female, NA, stage:T4N2M1, dead, 257 days
54.0
U0804
66 years, female, NA, stage:T3N2M1, dead, 380 days
54.0
U0243
69 years, female, NA, stage:T3N2M0, alive, 2975 days
53.9
U2779
74 years, male, NA, stage:T3N0M0, alive, 419 days
53.7
U0820
74 years, male, NA, stage:T3NXM1, dead, 622 days
53.6
U0713
63 years, male, NA, stage:T2N0M0, alive, 359 days
53.4
U0241
76 years, female, NA, stage:T2N1M0, alive, 552 days
53.3
U0080
86 years, female, NA, stage:T3N0M0, dead, 489 days
53.3
U0650
57 years, female, NA, stage:T2N2M0, alive, 1331 days
53.2
U0535
54 years, female, NA, stage:T4N1M0, alive, 2473 days
53.2
U0137
80 years, male, NA, stage:T3N1M0, dead, 1799 days
53.0
U0077
86 years, female, NA, stage:T2N0M0, dead, 588 days
52.6
U0417
54 years, female, NA, stage:T3N2M1, dead, 893 days
52.3
U0120
80 years, female, NA, stage:T3N0M0, alive, 3233 days
52.2
U0088
86 years, male, NA, stage:T3N1M1, dead, 260 days
52.1
U0430
55 years, male, NA, stage:T3N2M0, dead, 2472 days
52.0
U0380
62 years, male, NA, stage:T2N0M0, alive, 2155 days
51.9
U0364
67 years, female, NA, stage:T4N2M1, dead, 151 days
51.9
U0255
68 years, female, NA, stage:T3N2M0, dead, 1079 days
51.8
U0545
62 years, male, NA, stage:T3N0M0, alive, 2340 days
51.7
U0671
93 years, male, NA, stage:T3N1M0, dead, 785 days
51.7
U0212
77 years, male, NA, stage:T3N0M1, alive, 1330 days
51.6
U0578
42 years, male, NA, stage:T2N2M0, alive, 1724 days
51.0
U0079
86 years, male, NA, stage:T4N2M0, dead, 1891 days
50.8
U0128
86 years, female, NA, stage:T3N1M0, alive, 449 days
50.6
U0334
64 years, male, NA, stage:T3N1M0, alive, 3171 days
50.4
U0707
59 years, male, NA, stage:T3N1M0, alive, 518 days
50.4
U3049
72 years, male, NA, stage:T2N0M0, alive, 533 days
50.3
U0565
84 years, male, NA, stage:T4N1M0, alive, 1452 days
50.2
U0593
74 years, male, NA, stage:T4bN0M0, alive, 876 days
50.1
U0216
72 years, male, NA, stage:T2N0M0, alive, 2684 days
49.9
U0431
59 years, female, NA, stage:T3N1M0, alive, 695 days
49.9
U0519
69 years, male, NA, stage:T4N2M0, dead, 519 days
49.9
U0640
64 years, male, NA, stage:T2N0M0, alive, 1696 days
49.5
U0132
82 years, male, NA, stage:T3N1M0, alive, 1798 days
49.5
U0220
76 years, male, NA, stage:T2N0M0, alive, 1066 days
49.5
U0405
63 years, male, NA, stage:T3N1M0, alive, 829 days
49.5
U0638
52 years, male, NA, stage:T2N0M0, alive, 1801 days
49.4
U0658
75 years, male, NA, stage:T3N2M0, alive, 1108 days
49.3
U0402
58 years, female, NA, stage:T3N1M0, dead, 2487 days
49.2
U0587
47 years, male, NA, stage:T3N1M0, alive, 2107 days
49.1
U0258
73 years, male, NA, stage:T4N1M2, dead, 195 days
48.9
U0114
84 years, male, NA, stage:T3N0M0, alive, 1910 days
48.8
U0374
65 years, female, NA, stage:T2N0M0, alive, 1067 days
48.5
U0511
92 years, female, NA, stage:T3N0M0, dead, 2387 days
48.4
U3047
70 years, male, NA, stage:T3N2M0, alive, 205 days
48.2
U0174
81 years, male, NA, stage:T3N0M0, alive, 450 days
48.2
U0643
58 years, female, NA, stage:T2N1M0, dead, 1583 days
48.0
U0311
70 years, female, NA, stage:T3N1M0, alive, 1176 days
47.9
U0324
70 years, female, NA, stage:T4N1M0, alive, 938 days
47.9
U0293
67 years, male, NA, stage:T3N1M0, alive, 2717 days
47.8
U0192
76 years, male, NA, stage:T3N0M0, alive, 2081 days
47.7
U0802
70 years, male, NA, stage:T3N2M1, dead, 338 days
47.5
U0406
58 years, female, NA, stage:T4N2M1, dead, 778 days
47.5
U0339
64 years, male, NA, stage:T3N2M0, alive, 2155 days
47.2
U0604
67 years, male, NA, stage:T3N1M0, alive, 1522 days
47.1
U0466
40 years, male, NA, stage:T3N0M0, alive, 1381 days
47.0
U0458
49 years, male, NA, stage:T3N2M0, alive, 1073 days
47.0
U0264
69 years, male, NA, stage:T4N2M0, alive, 2020 days
46.5
U0116
85 years, male, NA, stage:T3N1M0, dead, 930 days
46.5
U0550
43 years, male, NA, stage:T3N2M0, alive, 2191 days
46.4
U0353
62 years, female, NA, stage:T1N0M0, alive, 2912 days
46.2
U0418
60 years, male, NA, stage:T4N1M0, alive, 1246 days
45.9
U0484
55 years, male, NA, stage:T4N2M0, alive, 1275 days
45.6
U0532
72 years, male, NA, stage:T3N0M0, dead, 730 days
45.6
U0861
62 years, female, NA, stage:T4N2M1, dead, 184 days
45.5
U0276
73 years, male, NA, stage:T3N1M1, alive, 934 days
45.5
U0437
57 years, male, NA, stage:T1N1M0, alive, 849 days
45.2
U0508
70 years, male, NA, stage:T3N1M0, alive, 1120 days
44.8
U0279
74 years, male, NA, stage:T2N1M0, dead, 176 days
44.8
U0485
74 years, male, NA, stage:T3N0M0, dead, 2737 days
44.7
U0568
59 years, male, NA, stage:T4N1M0, alive, 1287 days
44.4
U0299
71 years, female, NA, stage:T4N2M0, alive, 43426 days
44.4
U0581
66 years, female, NA, stage:T3N2M0, alive, 1660 days
44.2
U0213
71 years, male, NA, stage:T3N1M0, alive, 3018 days
44.2
U0814
80 years, female, NA, stage:T3N1M1, dead, 482 days
44.1
U0423
55 years, female, NA, stage:T4N2M0, alive, 2735 days
43.9
U0805
65 years, male, NA, stage:T3N1M1, dead, 731 days
43.8
U0603
73 years, male, NA, stage:T2N1M0, alive, 1904 days
43.7
U0579
65 years, female, NA, stage:T4aN0M0, alive, 2845 days
43.7
U0600
72 years, male, NA, stage:T3N1M0, alive, 1659 days
43.6
U0648
65 years, female, NA, stage:T3N0M0, alive, 1415 days
43.2
U0657
46 years, female, NA, stage:T2N0M0, dead, 1109 days
43.2
U0857
76 years, male, NA, stage:T4N2M1, dead, 954 days
43.2
U0557
51 years, female, NA, stage:T3N2M0, alive, 2009 days
43.2
U0351
63 years, female, NA, stage:T3N2M0, alive, 2886 days
43.2
U0553
68 years, female, NA, stage:T3N2M0, alive, 1704 days
43.1
U0359
64 years, male, NA, stage:T3N2M0, dead, 2443 days
43.0
U0409
61 years, female, NA, stage:T3N1M0, alive, 934 days
43.0
U0594
71 years, male, NA, stage:T3N0M0, alive, 2852 days
42.4
U0366
67 years, male, NA, stage:T3NXM1, alive, 895 days
42.3
U0498
72 years, female, NA, stage:T4N1M0, alive, 1906 days
42.1
U0388
61 years, male, NA, stage:T2N1M0, alive, 2186 days
42.1
U0605
74 years, male, NA, stage:T2N0M0, alive, 952 days
42.1
U0371
62 years, female, NA, stage:T3N0M0, alive, 2688 days
41.7
U0155
77 years, male, NA, stage:T2N0M0, dead, 1672 days
41.3
U0514
52 years, female, NA, stage:T2N2M0, alive, 2799 days
41.2
U0562
58 years, female, NA, stage:T3N1M0, alive, 3092 days
41.2
U0750
64 years, female, NA, stage:T3N2M0, dead, 1393 days
41.2
U0434
54 years, male, NA, stage:T2N0M0, alive, 2558 days
41.1
U0800
74 years, male, NA, stage:T3N2M1, dead, 411 days
41.1
U0591
81 years, male, NA, stage:T2N0M0, alive, 1023 days
40.9
U0457
50 years, male, NA, stage:T3N0M0, alive, 833 days
40.9
U0346
67 years, male, NA, stage:T4N2M0, alive, 1148 days
40.8
U0561
68 years, female, NA, stage:T3N2M0, alive, 1577 days
40.6
U0862
75 years, male, NA, stage:T4N2M1, dead, 1064 days
40.5
U0329
70 years, male, NA, stage:T3N1M0, dead, 805 days
40.4
U0492
63 years, male, NA, stage:T3N2M0, alive, 1114 days
40.2
U0649
67 years, male, NA, stage:T2N0M0, alive, 1424 days
40.1
U0497
66 years, female, NA, stage:T3N1M0, alive, 1414 days
40.1
U0577
59 years, female, NA, stage:T3N2M0, alive, 2474 days
40.1
U0596
61 years, male, NA, stage:T3N0M0, alive, 2233 days
40.0
U0552
67 years, male, NA, stage:T3N2M0, alive, 1701 days
39.8
U0558
63 years, female, NA, stage:T3N2M0, alive, 2011 days
39.7
U0534
69 years, female, NA, stage:T3N2M0, alive, 1361 days
39.7
U0602
79 years, male, NA, stage:T2N0M0, alive, 1385 days
39.5
U2943
79 years, male, NA, stage:T3N0M0, alive, 189 days
39.3
U0512
65 years, male, NA, stage:T3N0M0, alive, 2550 days
39.2
U0237
71 years, male, NA, stage:T3N1M0, alive, 2492 days
39.0
U0542
68 years, male, NA, stage:T3N2M0, dead, 1482 days
38.6
U0666
59 years, male, NA, stage:T3N1M0, alive, 709 days
38.5
U0304
68 years, male, NA, stage:T3N2M0, alive, 2065 days
38.5
U0159
79 years, female, NA, stage:T3N1M0, alive, 1517 days
38.1
U0556
66 years, male, NA, stage:T3N2M0, alive, 2037 days
38.1
U0284
73 years, male, NA, stage:T3N2M0, alive, 581 days
38.1
U0325
67 years, male, NA, stage:T3N0M0, dead, 1947 days
37.7
U0595
71 years, male, NA, stage:T2N0M0, alive, 2535 days
36.8
U0331
64 years, male, NA, stage:T3N1M1, dead, 906 days
36.5
U0584
66 years, male, NA, stage:T3N2M0, alive, 2705 days
36.2
U0138
80 years, male, NA, stage:T3N1M0, dead, 2472 days
36.1
U0194
79 years, male, NA, stage:T3N1M0, alive, 680 days
36.0
U0694
85 years, male, NA, stage:T4N0M0, dead, 489 days
35.6
U0294
73 years, male, NA, stage:T4N0M1, alive, 561 days
35.5
U0470
39 years, female, NA, stage:T2N2M0, alive, 961 days
35.5
U0190
75 years, male, NA, stage:T3N0M0, alive, 2367 days
35.3
U0642
87 years, male, NA, stage:T3N0M0, alive, 1603 days
34.3
U0572
67 years, female, NA, stage:T3N1M0, alive, 2621 days
34.2
U0686
77 years, female, NA, stage:T4bN0M0, dead, 123 days
34.2
U0468
38 years, female, NA, stage:T3N0M0, alive, 1921 days
34.2
U0097
83 years, male, NA, stage:T3N0M1, dead, 2903 days
33.6
U0675
84 years, female, NA, stage:T4N1M0, dead, 89 days
33.2
U0848
86 years, male, NA, stage:T3N1M1, dead, 1185 days
33.1
U0478
75 years, male, NA, stage:T4N2M0, alive, 2051 days
32.8
U0865
72 years, female, NA, stage:T3N1M1, dead, 856 days
32.2
U0298
72 years, male, NA, stage:T3N1M0, alive, 513 days
32.1
U0242
69 years, male, NA, stage:T3N0M0, alive, 2950 days
31.8
U0188
76 years, female, NA, stage:T3N1M0, alive, 2134 days
30.9
U0793
80 years, male, NA, stage:T3N1M1, dead, 195 days
30.9
U0533
68 years, male, NA, stage:T3N2M0, alive, 2248 days
30.3
U0147
78 years, female, NA, stage:T3N0M0, dead, 2085 days
29.7
U0539
66 years, male, NA, stage:T4N2M0, alive, 2017 days
29.4
U0555
60 years, male, NA, stage:T3N2M0, alive, 2043 days
27.7
U0576
69 years, male, NA, stage:T3N2M0, alive, 2540 days
27.4
U0205
72 years, female, NA, stage:T3N2M0, alive, 2984 days
26.8
U0271
69 years, female, NA, stage:T3N1M0, alive, 2414 days
25.7
U0322
67 years, male, NA, stage:T4N2M0, alive, 1694 days
24.7
U0228
76 years, male, NA, stage:T2N0M0, alive, 963 days
24.3
U0093
85 years, male, NA, stage:T3N2M0, dead, 1118 days
23.8
U0647
85 years, female, NA, stage:T3N0M0, alive, 1476 days
23.1
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COLON ADENOCARCINOMA - Protein relative expression (CPTAC)
Number of samples
197
Samples
Sample ID
Sample type
nRPX
b2400046-1d25-429d-a821-6040a6
Tumor
0.7
c9f0f144-47f3-4d64-b29f-bcedfa_D2
Normal
0.4
c9730cb4-b52c-4ca8-9652-4509d0_D2
Tumor
0.4
348f6009-e1be-44d2-a093-9ca844_D2
Normal
0.4
bc574f73-89ba-44d7-992e-82622c_D3
Tumor
0.4
ea6df59d-5240-4927-b19d-d44590_D2
Tumor
0.4
411d9597-c785-4de5-b449-29a80d_D2
Normal
0.3
43bc845e-d22e-4c10-b3e8-bc54e6_D2
Normal
0.3
e196a0b4-2a05-43de-bb30-ceb761_D2
Tumor
0.3
372c900a-fced-4eef-9dc4-7282ec_D2
Tumor
0.3
d7608884-a0d6-4e9e-aac7-6cd813_D3
Tumor
0.3
8cc7e656-0152-4359-8566-0581c3
Tumor
0.3
64ed43a2-f083-43cb-9d0d-118495_D2
Normal
0.3
46dfc1e4-0110-4d9f-888e-6a29ab_D2
Normal
0.3
0784c7b3-e6a4-42a8-9288-eb4ba0_D2
Normal
0.3
3765c09a-fff7-4b37-bf2b-452b23_D2
Normal
0.3
642fc6c3-8d4a-4e3d-ad0a-cc088a_D2
Tumor
0.3
e3c012aa-51c2-42b0-a478-bd620f_D2
Normal
0.3
bd67de01-ad7d-431a-9ad6-4dd5a1
Tumor
0.3
515040a4-bbfb-4a15-9e53-e7b6e6_D2
Normal
0.3
803736b3-9ca9-4f9f-bdfe-8783e3_D3
Tumor
0.3
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Tumor
0.3
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Normal
0.2
cbd0e774-c741-4753-9c9e-391a7d_D2
Normal
0.2
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Normal
0.2
c65afd57-530c-4366-b2c8-463a46_D2
Tumor
0.2
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Normal
0.2
8fab37a4-cdf9-4ce8-9081-7b9148_D2
Normal
0.2
5de06adb-e00d-4114-8d76-04bd30_D2
Normal
0.2
54565eae-05c5-4dae-bde9-ae4874_D2
Normal
0.2
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Normal
0.2
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Tumor
0.2
1fbb1add-4660-4ec1-b8c2-360f9f_D2
Normal
0.2
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Normal
0.2
9a48cf57-e1f0-4ea1-9804-d563f2_D2
Normal
0.2
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Normal
0.2
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Normal
0.2
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Tumor
0.2
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Normal
0.2
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Normal
0.2
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Tumor
0.2
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Tumor
0.2
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Normal
0.2
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Normal
0.2
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Tumor
0.2
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Tumor
0.2
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Normal
0.2
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Normal
0.2
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Normal
0.2
0f757044-9bc8-4ed4-90f3-e0a49a_D3
Tumor
0.2
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Tumor
0.2
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Normal
0.2
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Tumor
0.1
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Tumor
0.1
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Normal
0.1
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Normal
0.1
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Normal
0.1
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Tumor
0.1
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Tumor
0.1
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Normal
0.1
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Normal
0.1
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Tumor
0.1
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Normal
0.1
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Normal
0.1
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Tumor
0.1
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Tumor
0.1
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Normal
0.1
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Normal
0.1
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Normal
0.1
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Normal
0.1
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Normal
0.1
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Normal
0.1
23e938d0-92b8-4aea-90c1-4385df_D2
Normal
0.1
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Normal
0.1
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Normal
0.1
3e8019e8-125f-4615-a1fa-a448e9_D2
Normal
0.1
067db520-1b1f-4569-9414-e37a6e_D2
Normal
0.1
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Normal
0.1
176d1b96-8c6e-44fe-8a32-e15194_D2
Normal
0.1
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Normal
0.1
5271982c-5de1-4d6e-b414-b1f3ef_D2
Tumor
0.1
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Tumor
0.1
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Normal
0.1
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Normal
0.1
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Tumor
0.1
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Normal
0.1
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Normal
0.1
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Normal
0.1
21cab01c-e968-42cc-9651-1e53c0_D3
Tumor
0.1
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Normal
0.1
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Normal
0.1
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Normal
0.1
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Normal
0.1
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Normal
0.1
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Tumor
0.1
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Normal
0.1
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Tumor
0.1
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Normal
0.1
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Tumor
0.0
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Tumor
0.0
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Normal
0.0
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Normal
0.0
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Tumor
0.0
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Normal
0.0
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Tumor
0.0
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Normal
0.0
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Tumor
0.0
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Tumor
0.0
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Tumor
0.0
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Tumor
0.0
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Tumor
0.0
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Normal
0.0
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Tumor
0.0
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Normal
0.0
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Normal
0.0
903d5fe0-970a-47be-a97f-3cc914_D2
Normal
0.0
5a3aa99d-ca10-45f6-939f-12392a_D2
Normal
0.0
1c070992-647b-4173-a481-904c4d_D2
Normal
0.0
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Normal
0.0
1425a1a1-c835-47a2-a9b9-4db5d0_D8
Tumor
0.0
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Normal
0.0
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Tumor
0.0
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Normal
0.0
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Tumor
0.0
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Tumor
0.0
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Tumor
0.0
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Normal
0.0
cfb4831f-e9ee-4e11-80fb-958f6f_D2
Tumor
0.0
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Tumor
0.0
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Normal
0.0
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Normal
0.0
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Tumor
0.0
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Tumor
0.0
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Tumor
-0.1
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Normal
-0.1
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Tumor
-0.1
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Normal
-0.1
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Normal
-0.1
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Normal
-0.1
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Tumor
-0.1
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Tumor
-0.1
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Tumor
-0.1
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Normal
-0.1
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Tumor
-0.1
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Tumor
-0.1
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Tumor
-0.1
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Normal
-0.1
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Normal
-0.1
6b0a3188-d8ca-4d50-a377-a8fe4c_D2
Normal
-0.1
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Tumor
-0.1
6797a69d-2f74-44b9-8147-cd4fac_D2
Normal
-0.1
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Normal
-0.1
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Tumor
-0.1
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Tumor
-0.1
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Normal
-0.1
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Normal
-0.1
2f8b02e4-1848-4abc-a95e-dd9eb5_D3
Tumor
-0.1
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Normal
-0.1
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Tumor
-0.1
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Normal
-0.1
233ec093-9a30-4ef4-a12c-91757e_D2
Normal
-0.1
1f79fed9-f0d4-4c45-acd2-ea1441_D2
Normal
-0.1
b605fafc-f7dd-44cc-9c86-da04e3_D2
Tumor
-0.1
5f823547-ee16-45b7-a6a0-ef25d6_D3
Tumor
-0.1
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Tumor
-0.1
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Tumor
-0.1
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Tumor
-0.1
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Tumor
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Tumor
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Tumor
-0.2
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Tumor
-0.2
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Tumor
-0.2
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Tumor
-0.2
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Tumor
-0.2
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Tumor
-0.2
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Tumor
-0.2
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Tumor
-0.2
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Tumor
-0.2
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Tumor
-0.2
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Normal
-0.2
05a33362-82bb-48ac-8feb-ad2ea1_D2
Tumor
-0.2
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Tumor
-0.2
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Tumor
-0.2
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Tumor
-0.2
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Normal
-0.2
4cdeecb5-19fb-493c-91f5-eb0efc_D3
Tumor
-0.2
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Tumor
-0.2
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Tumor
-0.2
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Tumor
-0.3
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Normal
-0.3
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Tumor
-0.3
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Tumor
-0.3
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Tumor
-0.3
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Tumor
-0.3
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Tumor
-0.3
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Normal
-0.4
37219a7c-6fe2-4684-a494-d0be08_D2
Tumor
-0.5
Show allShow less
COLORECTAL CANCER - Protein expressioni
A mouse-over function shows sample information and annotation data. Click on an image to view it in a full screen mode. Samples can be filtered based on level of antibody staining by selecting one or several of the following categories: high, medium, low and not detected. The assay and annotation is described here.
Note that samples used for immunohistochemistry by the Human Protein Atlas do not correspond to samples in the TCGA dataset.
Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
The Human Protein Atlas project is funded
