Transcription factor landscape - Immune cell - dendritic cells

Transcriptome analysis shows that 50% (n=9998) of all human proteins (n=20162) are detected in dendritic cells and 582 of these genes show an elevated expression in any dendritic cells compared to other cell type groups. Learn more about genes with elevated expression here.

In-depth analysis of transcription factor genes expressed in dendritic cells highlights 39 transcription factors with elevated expression in dendritic cells compared to other immune lineages. In total, 12 transcription factors are classified as enriched in dendritic cells.

Here we provide the expression overview of all transcription factors that show enriched expression levels in dendritic cells compared to other cell types. The gene expression overview, across different cell types is accopanied by the top 3 nearest neighbours based on single cell RNA expression and correlation in the clustering analysis.

Enriched transcription factors

Gene

Expression

Expression clustering

CUX2

Lineage enriched (Dendritic cells)

3 nearest neighbours based on single cell RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data.	Clusterⁱ ID of the expression cluster of the neighboring gene.
KCNK10	Potassium two pore domain channel subfamily K member 10	1.0000	44
ETV2	ETS variant transcription factor 2	1.0000	44
PTPRS	Protein tyrosine phosphatase receptor type S	1.0000	44

MYBL2

Lineage enriched (Dendritic cells)

3 nearest neighbours based on single cell RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data.	Clusterⁱ ID of the expression cluster of the neighboring gene.
DERL3	Derlin 3	1.0000	44
ETV2	ETS variant transcription factor 2	1.0000	44
PTPRS	Protein tyrosine phosphatase receptor type S	1.0000	44

ZFAT

Lineage enriched (Dendritic cells)

3 nearest neighbours based on single cell RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data.	Clusterⁱ ID of the expression cluster of the neighboring gene.
XXYLT1	Xyloside xylosyltransferase 1	1.0000	29
EGLN3	Egl-9 family hypoxia inducible factor 3	1.0000	29
PLD4	Phospholipase D family member 4	1.0000	29

IRF7

Lineage enriched (Dendritic cells)

3 nearest neighbours based on single cell RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data.	Clusterⁱ ID of the expression cluster of the neighboring gene.
MAP2K1	Mitogen-activated protein kinase kinase 1	1.0000	44
SLC2A8	Solute carrier family 2 member 8	1.0000	44
TUBG1	Tubulin gamma 1	1.0000	44

EHF

Lineage enriched (Dendritic cells)

3 nearest neighbours based on single cell RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data.	Clusterⁱ ID of the expression cluster of the neighboring gene.
MRC1	Mannose receptor C-type 1	0.9762	2
DHRS4L2	Dehydrogenase/reductase 4 like 2	0.9762	2
ERICH5	Glutamate rich 5	0.9762	2

ZNF556

Lineage enriched (Dendritic cells)

3 nearest neighbours based on single cell RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data.	Clusterⁱ ID of the expression cluster of the neighboring gene.
PACSIN1	Protein kinase C and casein kinase substrate in neurons 1	1.0000	8
CFAP251	Cilia and flagella associated protein 251	1.0000	8
BEND6	BEN domain containing 6	1.0000	8

ZNF366

Lineage enriched (Dendritic cells)

3 nearest neighbours based on single cell RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data.	Clusterⁱ ID of the expression cluster of the neighboring gene.
CD1E	CD1e molecule	1.0000	2
GPR33	G protein-coupled receptor 33	1.0000	2
GEM	GTP binding protein overexpressed in skeletal muscle	1.0000	2

IRF8

Lineage enriched (Dendritic cells)

3 nearest neighbours based on single cell RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data.	Clusterⁱ ID of the expression cluster of the neighboring gene.
KCNK10	Potassium two pore domain channel subfamily K member 10	1.0000	44
ETV2	ETS variant transcription factor 2	1.0000	44
PTPRS	Protein tyrosine phosphatase receptor type S	1.0000	44

ETV2

Lineage enriched (Dendritic cells)

3 nearest neighbours based on single cell RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data.	Clusterⁱ ID of the expression cluster of the neighboring gene.
DERL3	Derlin 3	1.0000	44
PTPRS	Protein tyrosine phosphatase receptor type S	1.0000	44
SHD	Src homology 2 domain containing transforming protein D	1.0000	44

SNAI1

Lineage enriched (Dendritic cells)

3 nearest neighbours based on single cell RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data.	Clusterⁱ ID of the expression cluster of the neighboring gene.
SCARB1	Scavenger receptor class B member 1	1.0000	2
NEGR1	Neuronal growth regulator 1	1.0000	2
P2RY6	Pyrimidinergic receptor P2Y6	1.0000	2

FOSL1

Lineage enriched (Dendritic cells)

3 nearest neighbours based on single cell RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data.	Clusterⁱ ID of the expression cluster of the neighboring gene.
CST3	Cystatin C	0.9524	10
MACROH2A1	MacroH2A.1 histone	0.9524	10
NAGK	N-acetylglucosamine kinase	0.9524	10

PBX3

Lineage enriched (Dendritic cells)

3 nearest neighbours based on single cell RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data.	Clusterⁱ ID of the expression cluster of the neighboring gene.
CLASP2	Cytoplasmic linker associated protein 2	0.9524	5
YPEL1	Yippee like 1	0.9286	8
PLCXD2	Phosphatidylinositol specific phospholipase C X domain containing 2	0.9048	30

Enriched transcription factors

Gene

Expression

Expression clustering

SPIB

Group enriched (B-cells, Dendritic cells)

3 nearest neighbours based on single cell RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data.	Clusterⁱ ID of the expression cluster of the neighboring gene.
BLNK	B cell linker	0.9762	12
TXNDC5	Thioredoxin domain containing 5	0.9762	12
MZB1	Marginal zone B and B1 cell specific protein	0.9762	12

MYCL

Group enriched (Dendritic cells, Monocytes)

3 nearest neighbours based on single cell RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data.	Clusterⁱ ID of the expression cluster of the neighboring gene.
SPOCK3	SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3	1.0000	2
COMT	Catechol-O-methyltransferase	1.0000	2
MAN2B1	Mannosidase alpha class 2B member 1	1.0000	2

MSC

Group enriched (B-cells, Dendritic cells, T-cells)

3 nearest neighbours based on single cell RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data.	Clusterⁱ ID of the expression cluster of the neighboring gene.
PTTG1	PTTG1 regulator of sister chromatid separation, securin	1.0000	16
TNFRSF19	TNF receptor superfamily member 19	0.9762	16
PCLAF	PCNA clamp associated factor	0.9762	16

BATF3

Group enriched (Dendritic cells, Monocytes)

3 nearest neighbours based on single cell RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data.	Clusterⁱ ID of the expression cluster of the neighboring gene.
FZD1	Frizzled class receptor 1	1.0000	40
RIOK3	RIO kinase 3	1.0000	40
NHSL1	NHS like 1	1.0000	40

TCF4

Group enriched (B-cells, Dendritic cells)

3 nearest neighbours based on single cell RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data.	Clusterⁱ ID of the expression cluster of the neighboring gene.
KCNK10	Potassium two pore domain channel subfamily K member 10	1.0000	44
ETV2	ETS variant transcription factor 2	1.0000	44
PTPRS	Protein tyrosine phosphatase receptor type S	1.0000	44

TFEC

Group enriched (B-cells, Dendritic cells, Monocytes)

3 nearest neighbours based on single cell RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data.	Clusterⁱ ID of the expression cluster of the neighboring gene.
CRIP3	Cysteine rich protein 3	1.0000	2
GPR33	G protein-coupled receptor 33	0.9762	2
PKIB	CAMP-dependent protein kinase inhibitor beta	0.9762	2

BCL11A

Group enriched (B-cells, Dendritic cells)

3 nearest neighbours based on single cell RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data.	Clusterⁱ ID of the expression cluster of the neighboring gene.
CYB561A3	Cytochrome b561 family member A3	1.0000	12
SPIB	Spi-B transcription factor	0.9762	12
MTG1	Mitochondrial ribosome associated GTPase 1	0.9762	12

CEBPA

Group enriched (Dendritic cells, Granulocytes, Monocytes)

3 nearest neighbours based on single cell RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data.	Clusterⁱ ID of the expression cluster of the neighboring gene.
DRAM1	DNA damage regulated autophagy modulator 1	1.0000	40
SPA17	Sperm autoantigenic protein 17	0.9762	10
SEZ6L	Seizure related 6 homolog like	0.9762	40

IRF5

Group enriched (B-cells, Dendritic cells, Monocytes)

3 nearest neighbours based on single cell RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data.	Clusterⁱ ID of the expression cluster of the neighboring gene.
STAC3	SH3 and cysteine rich domain 3	1.0000	38
AIFM3	Apoptosis inducing factor mitochondria associated 3	1.0000	38
FGD6	FYVE, RhoGEF and PH domain containing 6	1.0000	38

VDR

Group enriched (Dendritic cells, Granulocytes, Monocytes)

3 nearest neighbours based on single cell RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data.	Clusterⁱ ID of the expression cluster of the neighboring gene.
STX12	Syntaxin 12	1.0000	40
RYR1	Ryanodine receptor 1	1.0000	40
PRR16	Proline rich 16	1.0000	40

ATF5

Group enriched (Dendritic cells, Monocytes)

3 nearest neighbours based on single cell RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data.	Clusterⁱ ID of the expression cluster of the neighboring gene.
MFSD2A	Major facilitator superfamily domain containing 2A	1.0000	2
LHFPL6	LHFPL tetraspan subfamily member 6	0.9762	2
MGST2	Microsomal glutathione S-transferase 2	0.9762	2

ETS2

Group enriched (Dendritic cells, Granulocytes, Monocytes)

3 nearest neighbours based on single cell RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data.	Clusterⁱ ID of the expression cluster of the neighboring gene.
MTF1	Metal regulatory transcription factor 1	1.0000	38
FTH1	Ferritin heavy chain 1	1.0000	38
NPTN	Neuroplastin	1.0000	38

VENTX

Group enriched (Dendritic cells, Granulocytes, Monocytes)

3 nearest neighbours based on single cell RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data.	Clusterⁱ ID of the expression cluster of the neighboring gene.
MARCO	Macrophage receptor with collagenous structure	1.0000	40
TCN2	Transcobalamin 2	1.0000	40
TMEM255B	Transmembrane protein 255B	1.0000	40

GFI1

Group enriched (Dendritic cells, T-cells)

3 nearest neighbours based on single cell RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data.	Clusterⁱ ID of the expression cluster of the neighboring gene.
TRGV5	T cell receptor gamma variable 5	1.0000	1
IFNL1	Interferon lambda 1	1.0000	1
KLRK1	Killer cell lectin like receptor K1	0.9762	1

HOXA9

Group enriched (Dendritic cells, Granulocytes, Nk-cells)

3 nearest neighbours based on single cell RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data.	Clusterⁱ ID of the expression cluster of the neighboring gene.
POLR3G	RNA polymerase III subunit G	1.0000	32
ZNF559-ZNF177	ZNF559-ZNF177 readthrough	1.0000	32
TAPBP	TAP binding protein	1.0000	32

MITF

Group enriched (Dendritic cells, Granulocytes, Monocytes)

3 nearest neighbours based on single cell RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data.	Clusterⁱ ID of the expression cluster of the neighboring gene.
GPR162	G protein-coupled receptor 162	0.9762	38
RNF130	Ring finger protein 130	0.9762	38
RPN1	Ribophorin I	0.9762	38

ZNF521

Group enriched (Dendritic cells, Granulocytes)

3 nearest neighbours based on single cell RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data.	Clusterⁱ ID of the expression cluster of the neighboring gene.
PLAC8	Placenta associated 8	0.9762	8
ENSG00000286264	Novel protein	0.9762	8
KLRF2	Killer cell lectin like receptor F2	0.9762	8

ZNF710

Group enriched (Dendritic cells, Granulocytes, Monocytes)

3 nearest neighbours based on single cell RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data.	Clusterⁱ ID of the expression cluster of the neighboring gene.
CMTM6	CKLF like MARVEL transmembrane domain containing 6	0.9762	37
GNGT2	G protein subunit gamma transducin 2	0.9762	37
CALM2	Calmodulin 2	0.9762	37

IRF4

Group enriched (B-cells, Dendritic cells, T-cells)

3 nearest neighbours based on single cell RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data.	Clusterⁱ ID of the expression cluster of the neighboring gene.
NPIPA9	Nuclear pore complex interacting protein family, member A9	1.0000	23
TLR10	Toll like receptor 10	1.0000	23
PARM1	Prostate androgen-regulated mucin-like protein 1	1.0000	23

MEF2C

Group enriched (B-cells, Dendritic cells, Monocytes)

3 nearest neighbours based on single cell RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data.	Clusterⁱ ID of the expression cluster of the neighboring gene.
OLFML1	Olfactomedin like 1	1.0000	23
RUBCNL	Rubicon like autophagy enhancer	1.0000	23
UVRAG	UV radiation resistance associated	0.9762	23

MYB

Group enriched (Dendritic cells, Granulocytes)

3 nearest neighbours based on single cell RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data.	Clusterⁱ ID of the expression cluster of the neighboring gene.
C11orf58	Chromosome 11 open reading frame 58	1.0000	41
STMP1	Short transmembrane mitochondrial protein 1	1.0000	41
MFAP3L	Microfibril associated protein 3 like	1.0000	41

NANOG

Group enriched (Dendritic cells, Granulocytes)

3 nearest neighbours based on single cell RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data.	Clusterⁱ ID of the expression cluster of the neighboring gene.
PAPLN	Papilin, proteoglycan like sulfated glycoprotein	0.9762	2
BRD3	Bromodomain containing 3	0.9762	2
ENKD1	Enkurin domain containing 1	0.9524	2

PPARA

Group enriched (Dendritic cells, Granulocytes)

3 nearest neighbours based on single cell RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data.	Clusterⁱ ID of the expression cluster of the neighboring gene.
ORAI3	ORAI calcium release-activated calcium modulator 3	1.0000	22
EIF5	Eukaryotic translation initiation factor 5	1.0000	22
FZR1	Fizzy and cell division cycle 20 related 1	1.0000	22

SOX4

Group enriched (Dendritic cells, Granulocytes, Monocytes)

3 nearest neighbours based on single cell RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data.	Clusterⁱ ID of the expression cluster of the neighboring gene.
RC3H2	Ring finger and CCCH-type domains 2	1.0000	10
ATAT1	Alpha tubulin acetyltransferase 1	1.0000	10
RFT1	RFT1 homolog	1.0000	10

TSC22D1

Group enriched (Dendritic cells, Granulocytes, Nk-cells)

3 nearest neighbours based on single cell RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data.	Clusterⁱ ID of the expression cluster of the neighboring gene.
WIPF2	WAS/WASL interacting protein family member 2	1.0000	41
RMND5A	Required for meiotic nuclear division 5 homolog A	1.0000	41
PPIP5K2	Diphosphoinositol pentakisphosphate kinase 2	1.0000	41

RARG

Group enriched (Dendritic cells, T-cells)

3 nearest neighbours based on single cell RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data.	Clusterⁱ ID of the expression cluster of the neighboring gene.
TC2N	Tandem C2 domains, nuclear	1.0000	27
CCNI2	Cyclin I family member 2	1.0000	27
CD247	CD247 molecule	1.0000	27

ZXDC

Group enriched (Dendritic cells, Granulocytes, Monocytes)

3 nearest neighbours based on single cell RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data.	Clusterⁱ ID of the expression cluster of the neighboring gene.
BICD2	BICD cargo adaptor 2	0.9762	7
TMLHE	Trimethyllysine hydroxylase, epsilon	0.9524	7
LIMK1	LIM domain kinase 1	0.9524	7