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HEAD AND NECK SQUAMOUS CELL CARCINOMA (TCGA) - Interactive survival scatter ploti
The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.
The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".
Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.
Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.
& Survival analysisi
Kaplan-Meier plots summarize results from analysis of correlation between mRNA expression level and patient survival. Patients were divided based on level of expression into one of the two groups "low" (under cut off) or "high" (over cut off). X-axis shows time for survival (years) and y-axis shows the probability of survival, where 1.0 corresponds to 100 percent.
Survival analysis data not available.
HEAD AND NECK SQUAMOUS CELL CARCINOMA - Protein relative expression (CPTAC)
Number of samples
183
Samples
Sample ID
Sample type
nRPX
CPT0235910003
Tumor
0.7
CPT0087990003
Tumor
0.6
CPT0163410003
Tumor
0.6
CPT0245450003
Tumor
0.6
CPT0127050003
Tumor
0.6
CPT0163910003
Tumor
0.6
CPT0163160003
Tumor
0.5
CPT0246590003
Tumor
0.5
CPT0195680003
Tumor
0.5
CPT0094420004
Tumor
0.5
CPT0245630003
Tumor
0.5
CPT0250310003
Tumor
0.4
CPT0163650003
Tumor
0.4
CPT0245500003
Tumor
0.4
CPT0163530003
Tumor
0.4
CPT0201830004
Tumor
0.4
CPT0245550003
Tumor
0.4
CPT0220610003
Tumor
0.4
CPT0194420003
Tumor
0.4
CPT0123180003
Tumor
0.4
CPT0237130004
Tumor
0.4
CPT0011130005
Tumor
0.4
CPT0223970003
Tumor
0.4
CPT0248520003
Tumor
0.4
CPT0163340003
Tumor
0.4
CPT0281470002
Normal
0.3
CPT0013000004
Tumor
0.3
CPT0094490004
Tumor
0.3
CPT0013130003
Tumor
0.3
CPT0248330003
Tumor
0.3
CPT0184530003
Tumor
0.3
CPT0237620004
Tumor
0.3
CPT0226440003
Tumor
0.3
CPT0245230004
Tumor
0.3
CPT0163790003
Tumor
0.3
CPT0235470002
Normal
0.3
CPT0011290003
Tumor
0.3
CPT0162990004
Tumor
0.2
CPT0195860003
Tumor
0.2
CPT0088060004
Tumor
0.2
CPT0245600003
Tumor
0.2
CPT0235460003
Tumor
0.2
CPT0245060004
Tumor
0.2
CPT0243090003
Tumor
0.2
CPT0169740004
Normal
0.2
CPT0013210004
Tumor
0.2
CPT0162940003
Tumor
0.2
CPT0245300003
Tumor
0.2
CPT0229220002
Normal
0.2
CPT0095040003
Tumor
0.2
CPT0226130003
Tumor
0.2
CPT0237480004
Tumor
0.2
CPT0163480003
Tumor
0.2
CPT0226250004
Tumor
0.2
CPT0196210003
Tumor
0.2
CPT0245680003
Tumor
0.1
CPT0169640003
Tumor
0.1
CPT0245350003
Tumor
0.1
CPT0084630009
Tumor
0.1
CPT0236620003
Tumor
0.1
CPT0008960003
Normal
0.1
CPT0278700002
Normal
0.1
CPT0199880003
Tumor
0.1
CPT0245410003
Normal
0.1
CPT0194250003
Tumor
0.1
CPT0222180003
Tumor
0.1
CPT0199820003
Tumor
0.1
CPT0163600003
Tumor
0.1
CPT0163090003
Tumor
0.1
CPT0244940004
Tumor
0.1
CPT0163240003
Tumor
0.1
CPT0245730003
Tumor
0.1
CPT0176770003
Tumor
0.1
CPT0207870004
Tumor
0.1
CPT0163840003
Tumor
0.1
CPT0177010003
Tumor
0.1
CPT0248350003
Normal
0.1
CPT0008630003
Tumor
0.1
CPT0162890003
Tumor
0.1
CPT0245180003
Tumor
0.1
CPT0094350004
Tumor
0.1
CPT0094280004
Tumor
0.1
CPT0011320003
Normal
0.1
CPT0245400003
Tumor
0.1
CPT0246540003
Tumor
0.1
CPT0246670003
Tumor
0.1
CPT0177710003
Tumor
0.1
CPT0087820003
Tumor
0.0
CPT0013030003
Normal
0.0
CPT0222360003
Tumor
0.0
CPT0190850003
Tumor
0.0
CPT0241980004
Tumor
0.0
CPT0235920003
Normal
0.0
C3N-04275-05
Normal
0.0
CPT0177200003
Tumor
0.0
C3N-04276-06
Normal
0.0
CPT0223450003
Tumor
0.0
CPT0226030003
Tumor
0.0
CPT0008930003
Tumor
0.0
CPT0094560004
Tumor
0.0
CPT0245010003
Tumor
0.0
CPT0226390003
Tumor
0.0
CPT0194800003
Normal
0.0
C3N-00857-05
Normal
0.0
C3N-01758-04
Normal
-0.1
CPT0163430003
Normal
-0.1
CPT0163020003
Normal
-0.1
CPT0024810003
Tumor
-0.1
CPT0163490003
Normal
-0.1
CPT0226340003
Tumor
-0.1
CPT0194260003
Normal
-0.1
C3N-02693-06
Normal
-0.1
CPT0194960003
Tumor
-0.1
CPT0008520008
Tumor
-0.1
CPT0163800003
Normal
-0.1
CPT0163250003
Normal
-0.1
CPT0177390003
Tumor
-0.1
CPT0013460003
Normal
-0.1
CPT0245460003
Normal
-0.1
CPT0199700003
Tumor
-0.1
CPT0013430003
Tumor
-0.1
CPT0169730003
Tumor
-0.1
CPT0163170003
Normal
-0.1
CPT0226270003
Normal
-0.2
CPT0245140003
Normal
-0.2
CPT0123260003
Tumor
-0.2
C3N-01620-05
Normal
-0.2
CPT0013250003
Normal
-0.2
C3N-04279-05
Normal
-0.2
CPT0244890004
Tumor
-0.2
CPT0088010003
Normal
-0.2
CPT0256560003
Tumor
-0.2
CPT0226090003
Normal
-0.2
CPT0226350003
Normal
-0.2
CPT0084650004
Normal
-0.2
CPT0196040003
Tumor
-0.2
CPT0196060003
Normal
-0.2
CPT0245130003
Tumor
-0.2
CPT0088410003
Tumor
-0.2
CPT0226450003
Normal
-0.2
CPT0261520003
Tumor
-0.2
CPT0169890003
Tumor
-0.2
CPT0237500003
Normal
-0.2
CPT0163610003
Normal
-0.2
CPT0199890003
Normal
-0.2
CPT0163720003
Normal
-0.2
CPT0194790003
Tumor
-0.2
CPT0236870003
Normal
-0.2
CPT0123190003
Normal
-0.3
CPT0177220003
Normal
-0.3
CPT0246620003
Tumor
-0.3
CPT0237150003
Normal
-0.3
CPT0163860003
Normal
-0.3
CPT0199710003
Normal
-0.3
CPT0088080003
Normal
-0.3
CPT0094580003
Normal
-0.3
C3N-00295-05
Normal
-0.3
CPT0237640003
Normal
-0.3
CPT0222200003
Normal
-0.3
CPT0169920003
Normal
-0.3
CPT0199830003
Normal
-0.3
CPT0236850004
Tumor
-0.3
CPT0201860004
Normal
-0.3
CPT0242000004
Normal
-0.3
CPT0243140004
Normal
-0.3
CPT0190860003
Normal
-0.3
CPT0195880003
Normal
-0.4
CPT0088430003
Normal
-0.4
CPT0236640003
Normal
-0.4
CPT0220620003
Normal
-0.4
CPT0163740003
Tumor
-0.4
CPT0123280003
Normal
-0.4
CPT0223460003
Normal
-0.5
CPT0245560003
Normal
-0.5
CPT0245020003
Normal
-0.5
C3N-01859-04
Normal
-0.5
CPT0226400003
Normal
-0.6
CPT0195700003
Normal
-0.6
CPT0245190003
Normal
-0.7
CPT0229230003
Normal
N/A
CPT0169750003
Normal
N/A
CPT0229210003
Tumor
N/A
CPT0229190003
Tumor
N/A
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HEAD AND NECK CANCER - Protein expressioni
A mouse-over function shows sample information and annotation data. Click on an image to view it in a full screen mode. Samples can be filtered based on level of antibody staining by selecting one or several of the following categories: high, medium, low and not detected. The assay and annotation is described here.
Note that samples used for immunohistochemistry by the Human Protein Atlas do not correspond to samples in the TCGA dataset.
Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.