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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
Annotated protein expressioni
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA029165
Most of the normal tissues showed weak to moderate cytoplasmic positivity. Strong staining was observed in hepatocytes, subsets of renal tubuli and a few cases of squamous epithelia. Glial cells, pancreas, spleen and lymphoid reaction center cells were mainly negative.
HPA029167
Most normal tissues showed moderate to strong nucleolar staining with additional cytoplasmic positivity. Spleen, bile ducts, glandular cells in uterine cervix and glial cells were in general negative.
CAB028574
Distinct cytoplasmic positivity was observed in subsets of cells in exocrine pancreas and adrenal cortex. Placental trophoblasts as well as subsets of cells in respiratory epithelium, gastric glands and neurons displayed moderate cytoplasmic and occasional nuclear immunoreactivity. Remaining tissues were weakly stained or negative.