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The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.
The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".
Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.
Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.
& Survival analysisi
Kaplan-Meier plots summarize results from analysis of correlation between mRNA expression level and patient survival. Patients were divided based on level of expression into one of the two groups "low" (under cut off) or "high" (over cut off). X-axis shows time for survival (years) and y-axis shows the probability of survival, where 1.0 corresponds to 100 percent.
IGLC2 is not prognostic in Testicular Germ Cell Tumor (TCGA)
Stage:
Survival analysis
Current cut offi
Current cut-off shows the cut-off (FPKM) currently selected. It may be changed manually. When the current cut-off is changed, the vertical dashed line indicating cut-off, the interactive survival scatter plot and the Kaplan-Meier curve will be automatically adjusted to show results accordingly.
:
Best expression cut offi
Based on the FPKM value of each gene, patients were classified into two groups and association between prognosis (survival) and gene expression (FPKM) was examined. The best expression cut-off refers the FPKM value that yields maximal difference with regard to survival between the two groups at the lowest log-rank P-value. Best expression cut-off was selected based on survival analysis .
When clicking on this number, the vertical dashed line indicating cut-off, the interactive survival plot, and the Kaplan-Meier curve will be adjusted to show results based on the best expression cut-off.
Median expression refers to the median FPKM value calculated based on the gene expression (FPKM) data from all patients in this dataset. When clicking on this number, the vertical dashed line indicating cut-off, the interactive survival plot, and the Kaplan-Meier curve will be adjusted to show results based on the median expression.
Median follow up time refers to the median time (years) after diagnosis with this type of cancer, based on clinical data from all patients in this dataset.
: N/A
P scorei
Log-rank P value for Kaplan-Meier plot showing results from analysis of correlation between mRNA expression level and patient survival.
N/A
5-year survival highi
5-year survival for patients with higher expression than the expression cutoff.
For melanoma and glioma, 3-year survival is shown.
N/A
5-year survival lowi
5-year survival for patients with lower expression than the expression cutoff.
For melanoma and glioma, 3-year survival is shown.
N/A
TCGA RNA samplesi
RNA-seq data is reported as average FPKM (number Fragments Per Kilobase of exon per Million reads), generated by the The Cancer Genome Atlas (TCGA) .
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. FPKM values of the individual samples are presented next to the box plot.
Average TPM
3600.2
Number of samples
133
Samples
Sample
Description
TPM
TCGA-XE-AAOB-01A
0 years, male, white, stage:Stage IS, dead, 513 days
40735.8
TCGA-ZM-AA0H-01A
0 years, male, white, stage:Stage IS, alive, 1736 days
24563.3
TCGA-2G-AAGP-01A
0 years, male, white, stage:Stage IIA, alive, 4018 days
16415.9
TCGA-ZM-AA0F-01A
0 years, male, white, stage:Stage IA, alive, 681 days
15685.6
TCGA-XE-AAOD-01A
0 years, male, white, stage:Stage IB, alive, 2058 days
14717.2
TCGA-2G-AAFH-01A
0 years, male, white, stage:Stage IIB, alive, 1375 days
14239.5
TCGA-4K-AA1H-01A
0 years, male, white, stage:Stage IA, alive, 518 days
12016.9
TCGA-ZM-AA0B-01A
0 years, male, white, stage:Stage IA, alive, 838 days
11603.8
TCGA-ZM-AA0N-01A
0 years, male, white, stage:Stage IB, alive, 634 days
11320.1
TCGA-WZ-A7V5-01A
0 years, male, white, stage:Stage I, alive, 1061 days
10166.2
TCGA-2X-A9D5-01A
0 years, male, white, stage:Stage I, alive, 435 days
8986.4
TCGA-YU-A90W-01A
0 years, male, white, stage:Stage IA, alive, 1113 days
8937.7
TCGA-4K-AA1I-01A
0 years, male, white, stage:Stage IA, alive, 3 days
7796.7
TCGA-2G-AAF1-01A
0 years, male, asian, stage:Stage IS, alive, 1403 days
7750.3
TCGA-2G-AAH4-01A
0 years, male, white, stage:Stage II, alive, 6210 days
7639.6
TCGA-2G-AAEX-01A
0 years, male, white, stage:Stage IS, alive, 1259 days
7548.2
TCGA-ZM-AA06-01A
0 years, male, white, stage:Stage IB, alive, 1498 days
7540.7
TCGA-WZ-A7V3-01A
0 years, male, white, stage:Stage I, alive, 753 days
7263.8
TCGA-X3-A8G4-01A
0 years, male, white, stage:Stage IS, alive, 856 days
7130.5
TCGA-2G-AALP-01A
0 years, male, white, stage:Stage IIIB, alive, 2645 days
6529.1
TCGA-2G-AAGY-01A
0 years, male, white, stage:Stage IS, alive, 5329 days
6501.0
TCGA-2G-AAF8-01A
0 years, male, white, stage:Stage IA, alive, 3911 days
6372.3
TCGA-WZ-A8D5-01A
0 years, male, white, stage:'--, alive, 774 days
6193.4
TCGA-2G-AAGZ-01A
0 years, male, white, stage:Stage IIIA, alive, 5233 days
6061.1
TCGA-XE-AANV-01A
0 years, male, stage:Stage IB, alive, 1701 days
6017.1
TCGA-VF-A8AA-01A
0 years, male, white, stage:Stage I, alive, 1146 days
5957.1
TCGA-2G-AAH3-01A
0 years, male, white, stage:Stage I, alive, 1822 days
5927.5
TCGA-WZ-A7V4-01A
0 years, male, white, stage:Stage I, alive, 894 days
5920.1
TCGA-2G-AAGJ-01A
0 years, male, black or african american, stage:Stage IA, alive, 2938 days
5632.2
TCGA-2G-AAKH-01A
0 years, male, white, stage:Stage II, alive, 6862 days
5525.9
TCGA-SB-A6J6-01A
0 years, male, white, stage:Stage IA, alive, 413 days
5372.7
TCGA-2X-A9D6-01A
0 years, male, white, stage:Stage I, alive, 607 days
5211.2
TCGA-2G-AAHC-01A
0 years, male, white, stage:Stage IS, alive, 5539 days
5020.7
TCGA-2G-AAFM-01A
0 years, male, white, stage:Stage IIA, alive, 503 days
4995.9
TCGA-XE-A9SE-01A
0 years, male, white, stage:Stage IA, alive, 708 days
4886.6
TCGA-VF-A8AC-01A
0 years, male, white, stage:Stage IA, alive, 1083 days
4879.0
TCGA-XY-A9T9-01A
0 years, male, white, stage:Stage IS, alive, 281 days
4788.8
TCGA-ZM-AA0E-01A
0 years, male, white, stage:Stage IA, alive, 811 days
4614.1
TCGA-VF-A8AD-01A
0 years, male, white, stage:Stage IB, alive, 1006 days
4552.6
TCGA-XY-A89B-01A
0 years, male, white, stage:Stage IA, alive, 471 days
4451.1
TCGA-2G-AAFL-01A
0 years, male, white, stage:Stage IB, alive, 750 days
4449.0
TCGA-SB-A76C-01A
0 years, male, white, stage:'--, alive, 42 days
4053.1
TCGA-W4-A7U3-01A
0 years, male, white, stage:'--, alive, 149 days
3941.6
TCGA-2G-AAFO-01A
0 years, male, white, stage:Stage IIA, alive, 685 days
3916.3
TCGA-4K-AAAL-01A
0 years, male, white, stage:Stage IS, alive, 483 days
3858.2
TCGA-XE-AAOF-01A
0 years, male, asian, stage:Stage IA, alive, 1268 days
3824.6
TCGA-2G-AAFV-01A
0 years, male, white, stage:Stage IS, alive, 1389 days
3614.5
TCGA-2G-AAHN-01A
0 years, male, white, stage:Stage I, alive, 6445 days
3542.0
TCGA-VF-A8AE-01A
0 years, male, white, stage:Stage IA, alive, 727 days
3438.9
TCGA-XE-A8H4-01A
0 years, male, white, stage:Stage IA, alive, 559 days
3414.9
TCGA-S6-A8JW-01A
0 years, male, white, stage:Stage IS, alive, 698 days
3344.7
TCGA-SN-A84X-01A
0 years, male, white, stage:Stage IS, alive, 312 days
3317.0
TCGA-2G-AAG9-01A
0 years, male, white, stage:Stage IIIB, alive, 2234 days
3228.6
TCGA-XE-AANI-01A
0 years, male, white, stage:Stage IS, alive, 1041 days
3092.4
TCGA-YU-A90S-01A
0 years, male, white, stage:Stage IA, alive, 971 days
3038.5
TCGA-2G-AAHA-01A
0 years, male, white, stage:Stage IB, alive, 3349 days
3003.0
TCGA-SN-A6IS-01A
0 years, male, white, stage:Stage IS, alive, 496 days
2842.0
TCGA-ZM-AA0D-01A
0 years, male, white, stage:Stage IA, alive, 848 days
2831.4
TCGA-2G-AAFG-01A
0 years, male, white, stage:Stage IS, alive, 6183 days
2648.9
TCGA-YU-A90P-01A
0 years, male, white, stage:Stage IA, alive, 2069 days
2488.7
TCGA-W4-A7U2-01A
0 years, male, white, stage:'--, alive, 1263 days
2413.0
TCGA-2G-AAF4-01A
0 years, male, white, stage:Stage I, alive, 2315 days
2297.8
TCGA-VF-A8A9-01A
0 years, male, white, stage:Stage IA, alive, 1119 days
2216.2
TCGA-XE-AAOL-01A
0 years, male, black or african american, stage:Stage I, alive, 13 days
2114.3
TCGA-SN-A84W-01A
0 years, male, white, stage:Stage IS, alive, 293 days
2081.0
TCGA-2G-AAGK-01A
0 years, male, white, stage:Stage IS, alive, 3621 days
1937.8
TCGA-YU-A94D-01A
0 years, male, stage:Stage IIIB, alive, 2167 days
1926.3
TCGA-2G-AAGG-01A
0 years, male, white, stage:Stage IIIC, alive, 2611 days
1802.1
TCGA-2G-AAF6-01A
0 years, male, white, stage:Stage IS, alive, 3491 days
1701.6
TCGA-2G-AAFY-01A
0 years, male, white, stage:Stage IIA, alive, 1099 days
1679.6
TCGA-XE-AANJ-01A
0 years, male, white, stage:Stage IS, alive, 2007 days
1558.8
TCGA-2G-AAHG-01A
0 years, male, white, stage:Stage I, alive, 1819 days
1556.6
TCGA-XE-AAOJ-01A
0 years, male, white, stage:Stage IS, alive, 1550 days
1511.4
TCGA-2G-AAHL-01A
0 years, male, white, stage:Stage I, alive, 7081 days
1420.1
TCGA-YU-A90Y-01A
0 years, male, black or african american, stage:Stage IIIC, dead, 17 days
1354.7
TCGA-2G-AAG3-01A
0 years, male, white, stage:Stage IS, alive, 1593 days
1326.1
TCGA-2G-AAKG-01A
0 years, male, white, stage:Stage I, alive, 6598 days
1217.6
TCGA-XE-AAO4-01A
0 years, male, white, stage:Stage IA, alive, 367 days
1139.3
TCGA-XE-AANR-01A
0 years, male, white, stage:Stage I, alive, 14 days
1096.4
TCGA-XE-A8H5-01A
0 years, male, stage:Stage IS, alive, 1217 days
1081.2
TCGA-2G-AAH8-01A
0 years, male, white, stage:Stage IIIC, alive, 2248 days
1055.2
TCGA-ZM-AA05-01A
0 years, male, white, stage:Stage IIC, alive, 1126 days
1034.9
TCGA-2G-AAG8-01A
0 years, male, white, stage:Stage IB, alive, 2289 days
1034.9
TCGA-2G-AAGI-01A
0 years, male, white, stage:Stage IS, alive, 3137 days
981.0
TCGA-VF-A8AB-01A
0 years, male, black or african american, stage:Stage IA, alive, 760 days
961.8
TCGA-S6-A8JY-01A
0 years, male, white, stage:Stage IS, alive, 278 days
937.8
TCGA-YU-A912-01A
0 years, male, black or african american, stage:Stage IIIC, alive, 866 days
856.4
TCGA-2G-AAFN-01A
0 years, male, white, stage:Stage IIIB, alive, 773 days
809.2
TCGA-XY-A8S2-01A
0 years, male, white, stage:Stage I, alive, 672 days
743.2
TCGA-XE-AAOC-01A
0 years, male, white, stage:Stage IA, alive, 270 days
741.4
TCGA-2G-AAGT-01A
0 years, male, white, stage:Stage IS, alive, 4406 days
691.3
TCGA-2G-AAG0-01A
0 years, male, white, stage:Stage IS, alive, 1529 days
659.1
TCGA-YU-AA61-01A
0 years, male, white, stage:Stage IS, alive, 864 days
650.9
TCGA-2G-AAGN-01A
0 years, male, white, stage:Stage IIIB, alive, 3656 days
635.8
TCGA-2G-AAGF-01A
0 years, male, white, stage:Stage IS, alive, 2734 days
572.5
TCGA-YU-A90Q-01A
0 years, male, stage:Stage IB, alive, 1964 days
508.0
TCGA-2G-AAG7-01A
0 years, male, white, stage:Stage IS, alive, 2475 days
493.7
TCGA-XE-AAO6-01A
0 years, male, white, stage:Stage IA, alive, 240 days
485.5
TCGA-2G-AAGO-01A
0 years, male, white, stage:Stage IS, alive, 4026 days
474.4
TCGA-2G-AAFI-01A
0 years, male, white, stage:Stage IB, alive, 675 days
467.1
TCGA-2G-AAH0-01A
0 years, male, white, stage:Stage IS, alive, 5477 days
457.0
TCGA-2G-AAFZ-01A
0 years, male, white, stage:Stage III, alive, 1353 days
402.0
TCGA-2G-AAHP-01A
0 years, male, white, stage:Stage IS, alive, 5667 days
399.3
TCGA-2G-AAGA-01A
0 years, male, white, stage:Stage IIA, alive, 2439 days
365.0
TCGA-2G-AAH2-01A
0 years, male, white, stage:Stage IS, alive, 6060 days
320.7
TCGA-2G-AAGM-01A
0 years, male, white, stage:Stage IS, alive, 3891 days
289.6
TCGA-W4-A7U4-01A
0 years, male, white, stage:'--, alive, 738 days
270.3
TCGA-2G-AAEW-01A
0 years, male, white, stage:Stage IS, dead, 618 days
267.8
TCGA-2G-AAHT-01A
0 years, male, white, stage:Stage IS, alive, 542 days
254.8
TCGA-2G-AAKM-01A
0 years, male, white, stage:Stage II, dead, 6972 days
199.8
TCGA-2G-AAGE-01A
0 years, male, white, stage:Stage IS, alive, 2478 days
189.1
TCGA-2G-AAKD-01A
0 years, male, white, stage:Stage III, alive, 6340 days
179.3
TCGA-SO-A8JP-01A
0 years, male, white, stage:Stage I, alive, 540 days
177.9
TCGA-2G-AAKL-01A
0 years, male, white, stage:Stage II, alive, 7023 days
161.3
TCGA-2G-AAL7-01A
0 years, male, white, stage:Stage IS, alive, 3991 days
158.7
TCGA-XE-AAO3-01A
0 years, male, asian, stage:Stage I, alive, 2857 days
133.1
TCGA-2G-AAGC-01A
0 years, male, white, stage:Stage IS, alive, 2585 days
126.1
TCGA-XE-A8H1-01A
0 years, male, white, stage:Stage IS, alive, 209 days
119.7
TCGA-2G-AAG6-01A
0 years, male, white, stage:Stage IS, alive, 2231 days
118.6
TCGA-2G-AAFJ-01A
0 years, male, asian, stage:'--, alive, 792 days
115.8
TCGA-2G-AAFE-01A
0 years, male, white, stage:Stage IIA, alive, 4702 days
114.4
TCGA-2G-AAG5-01A
0 years, male, white, stage:Stage IS, alive, 2299 days
92.7
TCGA-YU-AA4L-01A
0 years, male, black or african american, stage:Stage IIIC, alive, 1573 days
82.1
TCGA-4K-AA1G-01A
0 years, male, white, stage:Stage IS, alive, 436 days
79.3
TCGA-2G-AAGV-01A
0 years, male, white, stage:'--, alive, 4527 days
48.4
TCGA-YU-A94I-01A
0 years, male, stage:Stage IA, alive, 536 days
41.2
TCGA-SN-A84Y-01A
0 years, male, white, stage:Stage IS, alive, 524 days
38.3
TCGA-VF-A8A8-01A
0 years, male, white, stage:Stage IA, alive, 1131 days
25.9
TCGA-2G-AAGX-01A
0 years, male, white, stage:Stage IA, alive, 5514 days
17.2
TCGA-2G-AAL5-01A
0 years, male, white, stage:Stage I, alive, 7437 days
4.2
TCGA-S6-A8JX-01A
0 years, male, white, stage:Stage IB, alive, 552 days
0.0
TCGA-2G-AAGS-01A
0 years, male, white, stage:Stage IIIB, alive, 4816 days
0.0
TCGA-2G-AAGW-01A
0 years, male, white, stage:Stage IS, alive, 4899 days
0.0
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TESTIS CANCER - Protein expressioni
A mouse-over function shows sample information and annotation data. Click on an image to view it in a full screen mode. Samples can be filtered based on level of antibody staining by selecting one or several of the following categories: high, medium, low and not detected. The assay and annotation is described here.
Note that samples used for immunohistochemistry by the Human Protein Atlas do not correspond to samples in the TCGA dataset.
The Human Protein Atlas project is funded
