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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
Annotated protein expressioni
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA042455
Macrophages of lung, gastrointestinal tract, exocrine pancreas, leydig cells, lymphoid tissues and renal glomeruli showed moderate to strong cytoplasmic positivity. Distinct reticular pattern was observed in lymphoid germinal centers. Remaining normal tissues were weakly stained or negative.
HPA043579
Lymphoid tissues exhibited moderate to strong cytoplasmic staining with distinct reticular pattern in germinal centers. Renal glomeruli were distinctly stained. Respiratory and squamous epithelia, gastrointestinal tract, exocrine pancreas, glandular cells in female genital tract and breast showed moderate cytoplasmic positivity with a granular pattern. Remaining normal tissues were mainly negative.
HPA049348
Glomeruli of kidney, fraction of bone marrow hematopoietic cells and lymphoid cells were distinctly stained. Most remaining normal tissues were negative.
CAB002491
Strong cytoplasmic positivity with a reticular pattern was observed in lymphatic tissues. Renal glomeruli showed strong membranous immunoreactivity. Remaining normal tissues were negative.
CAB016271
Highly selective cytoplasmic staining of glomeruli in kidney, white pulp in spleen and germinal center in tonsil. Virtually no staining in other tissues.
The Human Protein Atlas project is funded
