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The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.
The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".
Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.
Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.
& Survival analysisi
Kaplan-Meier plots summarize results from analysis of correlation between mRNA expression level and patient survival. Patients were divided based on level of expression into one of the two groups "low" (under cut off) or "high" (over cut off). X-axis shows time for survival (years) and y-axis shows the probability of survival, where 1.0 corresponds to 100 percent.
MT-ND5 is not prognostic in Testicular Germ Cell Tumor (TCGA)
Stage:
Survival analysis
Current cut offi
Current cut-off shows the cut-off (FPKM) currently selected. It may be changed manually. When the current cut-off is changed, the vertical dashed line indicating cut-off, the interactive survival scatter plot and the Kaplan-Meier curve will be automatically adjusted to show results accordingly.
:
Best expression cut offi
Based on the FPKM value of each gene, patients were classified into two groups and association between prognosis (survival) and gene expression (FPKM) was examined. The best expression cut-off refers the FPKM value that yields maximal difference with regard to survival between the two groups at the lowest log-rank P-value. Best expression cut-off was selected based on survival analysis .
When clicking on this number, the vertical dashed line indicating cut-off, the interactive survival plot, and the Kaplan-Meier curve will be adjusted to show results based on the best expression cut-off.
Median expression refers to the median FPKM value calculated based on the gene expression (FPKM) data from all patients in this dataset. When clicking on this number, the vertical dashed line indicating cut-off, the interactive survival plot, and the Kaplan-Meier curve will be adjusted to show results based on the median expression.
Median follow up time refers to the median time (years) after diagnosis with this type of cancer, based on clinical data from all patients in this dataset.
: N/A
P scorei
Log-rank P value for Kaplan-Meier plot showing results from analysis of correlation between mRNA expression level and patient survival.
N/A
5-year survival highi
5-year survival for patients with higher expression than the expression cutoff.
For melanoma and glioma, 3-year survival is shown.
N/A
5-year survival lowi
5-year survival for patients with lower expression than the expression cutoff.
For melanoma and glioma, 3-year survival is shown.
N/A
TCGA RNA samplesi
RNA-seq data is reported as average FPKM (number Fragments Per Kilobase of exon per Million reads), generated by the The Cancer Genome Atlas (TCGA) .
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. FPKM values of the individual samples are presented next to the box plot.
Average TPM
1485.5
Number of samples
133
Samples
Sample
Description
TPM
TCGA-ZM-AA06-01A
0 years, male, white, stage:Stage IB, alive, 1498 days
9198.6
TCGA-ZM-AA05-01A
0 years, male, white, stage:Stage IIC, alive, 1126 days
8155.8
TCGA-ZM-AA0E-01A
0 years, male, white, stage:Stage IA, alive, 811 days
8089.9
TCGA-XE-AAOL-01A
0 years, male, black or african american, stage:Stage I, alive, 13 days
7870.9
TCGA-XE-AAO6-01A
0 years, male, white, stage:Stage IA, alive, 240 days
6161.9
TCGA-ZM-AA0H-01A
0 years, male, white, stage:Stage IS, alive, 1736 days
5774.2
TCGA-ZM-AA0F-01A
0 years, male, white, stage:Stage IA, alive, 681 days
5488.1
TCGA-ZM-AA0N-01A
0 years, male, white, stage:Stage IB, alive, 634 days
4048.0
TCGA-2G-AAG6-01A
0 years, male, white, stage:Stage IS, alive, 2231 days
3768.8
TCGA-ZM-AA0D-01A
0 years, male, white, stage:Stage IA, alive, 848 days
3714.1
TCGA-YU-A90S-01A
0 years, male, white, stage:Stage IA, alive, 971 days
3321.5
TCGA-S6-A8JX-01A
0 years, male, white, stage:Stage IB, alive, 552 days
3296.5
TCGA-XE-AAO4-01A
0 years, male, white, stage:Stage IA, alive, 367 days
3240.5
TCGA-ZM-AA0B-01A
0 years, male, white, stage:Stage IA, alive, 838 days
3228.4
TCGA-2G-AAHG-01A
0 years, male, white, stage:Stage I, alive, 1819 days
2906.4
TCGA-VF-A8AB-01A
0 years, male, black or african american, stage:Stage IA, alive, 760 days
2172.4
TCGA-XY-A89B-01A
0 years, male, white, stage:Stage IA, alive, 471 days
2145.6
TCGA-YU-A94I-01A
0 years, male, stage:Stage IA, alive, 536 days
2134.2
TCGA-WZ-A7V4-01A
0 years, male, white, stage:Stage I, alive, 894 days
2086.4
TCGA-S6-A8JY-01A
0 years, male, white, stage:Stage IS, alive, 278 days
2072.7
TCGA-2G-AAGG-01A
0 years, male, white, stage:Stage IIIC, alive, 2611 days
2001.1
TCGA-2G-AAFE-01A
0 years, male, white, stage:Stage IIA, alive, 4702 days
1991.6
TCGA-YU-A912-01A
0 years, male, black or african american, stage:Stage IIIC, alive, 866 days
1981.7
TCGA-YU-A90Y-01A
0 years, male, black or african american, stage:Stage IIIC, dead, 17 days
1906.0
TCGA-2G-AAH2-01A
0 years, male, white, stage:Stage IS, alive, 6060 days
1903.6
TCGA-YU-A90W-01A
0 years, male, white, stage:Stage IA, alive, 1113 days
1884.7
TCGA-2G-AAG5-01A
0 years, male, white, stage:Stage IS, alive, 2299 days
1878.2
TCGA-2G-AAGV-01A
0 years, male, white, stage:'--, alive, 4527 days
1835.6
TCGA-XE-AAOC-01A
0 years, male, white, stage:Stage IA, alive, 270 days
1805.1
TCGA-YU-A90Q-01A
0 years, male, stage:Stage IB, alive, 1964 days
1788.2
TCGA-2G-AAG3-01A
0 years, male, white, stage:Stage IS, alive, 1593 days
1758.7
TCGA-2G-AAGY-01A
0 years, male, white, stage:Stage IS, alive, 5329 days
1751.6
TCGA-2G-AAKM-01A
0 years, male, white, stage:Stage II, dead, 6972 days
1666.4
TCGA-2G-AAH3-01A
0 years, male, white, stage:Stage I, alive, 1822 days
1592.4
TCGA-2G-AAG9-01A
0 years, male, white, stage:Stage IIIB, alive, 2234 days
1449.8
TCGA-XE-A8H4-01A
0 years, male, white, stage:Stage IA, alive, 559 days
1444.5
TCGA-2G-AAGP-01A
0 years, male, white, stage:Stage IIA, alive, 4018 days
1439.6
TCGA-SN-A84W-01A
0 years, male, white, stage:Stage IS, alive, 293 days
1432.8
TCGA-2X-A9D6-01A
0 years, male, white, stage:Stage I, alive, 607 days
1421.6
TCGA-2X-A9D5-01A
0 years, male, white, stage:Stage I, alive, 435 days
1420.6
TCGA-XE-AAOF-01A
0 years, male, asian, stage:Stage IA, alive, 1268 days
1419.2
TCGA-4K-AA1I-01A
0 years, male, white, stage:Stage IA, alive, 3 days
1417.3
TCGA-2G-AAFJ-01A
0 years, male, asian, stage:'--, alive, 792 days
1411.0
TCGA-WZ-A7V5-01A
0 years, male, white, stage:Stage I, alive, 1061 days
1393.9
TCGA-WZ-A7V3-01A
0 years, male, white, stage:Stage I, alive, 753 days
1340.9
TCGA-XE-AANI-01A
0 years, male, white, stage:Stage IS, alive, 1041 days
1337.1
TCGA-2G-AAHC-01A
0 years, male, white, stage:Stage IS, alive, 5539 days
1330.4
TCGA-YU-AA61-01A
0 years, male, white, stage:Stage IS, alive, 864 days
1289.4
TCGA-SN-A6IS-01A
0 years, male, white, stage:Stage IS, alive, 496 days
1279.4
TCGA-YU-A90P-01A
0 years, male, white, stage:Stage IA, alive, 2069 days
1277.5
TCGA-2G-AAGC-01A
0 years, male, white, stage:Stage IS, alive, 2585 days
1267.9
TCGA-2G-AAHA-01A
0 years, male, white, stage:Stage IB, alive, 3349 days
1226.9
TCGA-WZ-A8D5-01A
0 years, male, white, stage:'--, alive, 774 days
1220.1
TCGA-XE-AANJ-01A
0 years, male, white, stage:Stage IS, alive, 2007 days
1206.8
TCGA-2G-AAFV-01A
0 years, male, white, stage:Stage IS, alive, 1389 days
1194.3
TCGA-XE-A9SE-01A
0 years, male, white, stage:Stage IA, alive, 708 days
1179.1
TCGA-XE-AAOD-01A
0 years, male, white, stage:Stage IB, alive, 2058 days
1163.7
TCGA-XE-AANV-01A
0 years, male, stage:Stage IB, alive, 1701 days
1160.6
TCGA-2G-AAF4-01A
0 years, male, white, stage:Stage I, alive, 2315 days
1137.0
TCGA-W4-A7U4-01A
0 years, male, white, stage:'--, alive, 738 days
1109.7
TCGA-VF-A8A9-01A
0 years, male, white, stage:Stage IA, alive, 1119 days
1105.3
TCGA-YU-A94D-01A
0 years, male, stage:Stage IIIB, alive, 2167 days
1081.6
TCGA-XE-AAOJ-01A
0 years, male, white, stage:Stage IS, alive, 1550 days
1061.9
TCGA-2G-AAGM-01A
0 years, male, white, stage:Stage IS, alive, 3891 days
1036.9
TCGA-SB-A6J6-01A
0 years, male, white, stage:Stage IA, alive, 413 days
1019.4
TCGA-SB-A76C-01A
0 years, male, white, stage:'--, alive, 42 days
1018.9
TCGA-S6-A8JW-01A
0 years, male, white, stage:Stage IS, alive, 698 days
1015.8
TCGA-2G-AAH0-01A
0 years, male, white, stage:Stage IS, alive, 5477 days
1012.2
TCGA-2G-AAGE-01A
0 years, male, white, stage:Stage IS, alive, 2478 days
984.4
TCGA-2G-AAF8-01A
0 years, male, white, stage:Stage IA, alive, 3911 days
952.9
TCGA-W4-A7U3-01A
0 years, male, white, stage:'--, alive, 149 days
942.5
TCGA-2G-AAGS-01A
0 years, male, white, stage:Stage IIIB, alive, 4816 days
906.4
TCGA-2G-AAG0-01A
0 years, male, white, stage:Stage IS, alive, 1529 days
903.3
TCGA-2G-AAKL-01A
0 years, male, white, stage:Stage II, alive, 7023 days
889.3
TCGA-XE-A8H1-01A
0 years, male, white, stage:Stage IS, alive, 209 days
877.9
TCGA-SO-A8JP-01A
0 years, male, white, stage:Stage I, alive, 540 days
875.6
TCGA-4K-AA1H-01A
0 years, male, white, stage:Stage IA, alive, 518 days
859.1
TCGA-2G-AAL7-01A
0 years, male, white, stage:Stage IS, alive, 3991 days
841.9
TCGA-XY-A9T9-01A
0 years, male, white, stage:Stage IS, alive, 281 days
826.8
TCGA-YU-AA4L-01A
0 years, male, black or african american, stage:Stage IIIC, alive, 1573 days
823.5
TCGA-2G-AAG7-01A
0 years, male, white, stage:Stage IS, alive, 2475 days
822.1
TCGA-2G-AAGI-01A
0 years, male, white, stage:Stage IS, alive, 3137 days
809.2
TCGA-2G-AAKD-01A
0 years, male, white, stage:Stage III, alive, 6340 days
800.3
TCGA-2G-AAGX-01A
0 years, male, white, stage:Stage IA, alive, 5514 days
784.1
TCGA-2G-AAGO-01A
0 years, male, white, stage:Stage IS, alive, 4026 days
781.4
TCGA-2G-AAFG-01A
0 years, male, white, stage:Stage IS, alive, 6183 days
773.8
TCGA-W4-A7U2-01A
0 years, male, white, stage:'--, alive, 1263 days
752.5
TCGA-VF-A8AE-01A
0 years, male, white, stage:Stage IA, alive, 727 days
748.2
TCGA-2G-AAH8-01A
0 years, male, white, stage:Stage IIIC, alive, 2248 days
744.9
TCGA-XE-AAO3-01A
0 years, male, asian, stage:Stage I, alive, 2857 days
728.9
TCGA-XY-A8S2-01A
0 years, male, white, stage:Stage I, alive, 672 days
727.2
TCGA-XE-AAOB-01A
0 years, male, white, stage:Stage IS, dead, 513 days
716.2
TCGA-2G-AAFY-01A
0 years, male, white, stage:Stage IIA, alive, 1099 days
715.5
TCGA-XE-A8H5-01A
0 years, male, stage:Stage IS, alive, 1217 days
707.0
TCGA-2G-AAGA-01A
0 years, male, white, stage:Stage IIA, alive, 2439 days
699.6
TCGA-2G-AAKH-01A
0 years, male, white, stage:Stage II, alive, 6862 days
699.5
TCGA-4K-AAAL-01A
0 years, male, white, stage:Stage IS, alive, 483 days
697.8
TCGA-2G-AAKG-01A
0 years, male, white, stage:Stage I, alive, 6598 days
691.4
TCGA-2G-AAFH-01A
0 years, male, white, stage:Stage IIB, alive, 1375 days
686.1
TCGA-VF-A8AA-01A
0 years, male, white, stage:Stage I, alive, 1146 days
671.5
TCGA-2G-AAGT-01A
0 years, male, white, stage:Stage IS, alive, 4406 days
662.7
TCGA-2G-AAFI-01A
0 years, male, white, stage:Stage IB, alive, 675 days
661.3
TCGA-2G-AAEW-01A
0 years, male, white, stage:Stage IS, dead, 618 days
658.6
TCGA-2G-AAEX-01A
0 years, male, white, stage:Stage IS, alive, 1259 days
645.5
TCGA-2G-AAHT-01A
0 years, male, white, stage:Stage IS, alive, 542 days
638.4
TCGA-2G-AAL5-01A
0 years, male, white, stage:Stage I, alive, 7437 days
583.2
TCGA-2G-AAGN-01A
0 years, male, white, stage:Stage IIIB, alive, 3656 days
578.6
TCGA-2G-AAGF-01A
0 years, male, white, stage:Stage IS, alive, 2734 days
574.3
TCGA-2G-AAF1-01A
0 years, male, asian, stage:Stage IS, alive, 1403 days
571.5
TCGA-2G-AAGZ-01A
0 years, male, white, stage:Stage IIIA, alive, 5233 days
563.7
TCGA-VF-A8AD-01A
0 years, male, white, stage:Stage IB, alive, 1006 days
551.9
TCGA-2G-AAH4-01A
0 years, male, white, stage:Stage II, alive, 6210 days
534.2
TCGA-2G-AAFZ-01A
0 years, male, white, stage:Stage III, alive, 1353 days
525.9
TCGA-SN-A84Y-01A
0 years, male, white, stage:Stage IS, alive, 524 days
520.3
TCGA-2G-AAFL-01A
0 years, male, white, stage:Stage IB, alive, 750 days
461.6
TCGA-2G-AAHN-01A
0 years, male, white, stage:Stage I, alive, 6445 days
460.4
TCGA-2G-AAG8-01A
0 years, male, white, stage:Stage IB, alive, 2289 days
457.2
TCGA-2G-AAGK-01A
0 years, male, white, stage:Stage IS, alive, 3621 days
433.9
TCGA-XE-AANR-01A
0 years, male, white, stage:Stage I, alive, 14 days
433.2
TCGA-2G-AALP-01A
0 years, male, white, stage:Stage IIIB, alive, 2645 days
427.0
TCGA-2G-AAF6-01A
0 years, male, white, stage:Stage IS, alive, 3491 days
422.9
TCGA-VF-A8A8-01A
0 years, male, white, stage:Stage IA, alive, 1131 days
401.3
TCGA-4K-AA1G-01A
0 years, male, white, stage:Stage IS, alive, 436 days
393.3
TCGA-X3-A8G4-01A
0 years, male, white, stage:Stage IS, alive, 856 days
393.3
TCGA-2G-AAGW-01A
0 years, male, white, stage:Stage IS, alive, 4899 days
384.4
TCGA-VF-A8AC-01A
0 years, male, white, stage:Stage IA, alive, 1083 days
369.6
TCGA-2G-AAGJ-01A
0 years, male, black or african american, stage:Stage IA, alive, 2938 days
361.7
TCGA-2G-AAFO-01A
0 years, male, white, stage:Stage IIA, alive, 685 days
340.4
TCGA-2G-AAFN-01A
0 years, male, white, stage:Stage IIIB, alive, 773 days
306.8
TCGA-SN-A84X-01A
0 years, male, white, stage:Stage IS, alive, 312 days
297.6
TCGA-2G-AAFM-01A
0 years, male, white, stage:Stage IIA, alive, 503 days
287.7
TCGA-2G-AAHL-01A
0 years, male, white, stage:Stage I, alive, 7081 days
220.8
TCGA-2G-AAHP-01A
0 years, male, white, stage:Stage IS, alive, 5667 days
73.1
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TESTIS CANCER - Protein expressioni
A mouse-over function shows sample information and annotation data. Click on an image to view it in a full screen mode. Samples can be filtered based on level of antibody staining by selecting one or several of the following categories: high, medium, low and not detected. The assay and annotation is described here.
Note that samples used for immunohistochemistry by the Human Protein Atlas do not correspond to samples in the TCGA dataset.