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CARD11
HPA
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                                        • CARD11
                                        TISSUE PRIMARY DATA TISSUES Show tissue menu
                                        ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BONE MARROW BREAST BRONCHUS CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON DUODENUM
                                        ENDOMETRIUM EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MIDBRAIN NASOPHARYNX
                                        ORAL MUCOSA OVARY PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN SMALL INTESTINE
                                        SMOOTH MUSCLE SOFT TISSUE SPINAL CORD SPLEEN STOMACH TESTIS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA
                                        ANTIBODIES
                                        AND
                                        VALIDATION
                                        Dictionary
                                        Tissue proteome
                                        ANTIBODY PRIMARY DATAi

                                        The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.

                                        The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.

                                        For histological reference, visit the histological dictionary.

                                        Antibodies in assayi

                                        The internal antibody ID for the antibody/antibodies available for this specific target, click link for more antibody information.

                                        HPA052984
                                        Tissue presentation order  
                                        Organ
                                        Cell type
                                        Alphabetical
                                        Tissue Antibody stainingi

                                        This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.

                                        Annotated protein expressioni

                                        This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.

                                        HPA052984

                                        h
                                        m
                                        l
                                        n
                                        h
                                        m
                                        l
                                        n
                                        Brain
                                        Cerebral cortex Neuronal cells
                                        Cerebral cortex Endothelial cells
                                        Cerebral cortex Glial cells
                                        Cerebral cortex Neuropil
                                        Hippocampus Neuronal cells
                                        Hippocampus Glial cells
                                        Caudate Neuronal cells
                                        Caudate Glial cells
                                        Cerebellum Purkinje cells
                                        Cerebellum Cells in granular layer
                                        Cerebellum Cells in molecular layer
                                        Endocrine tissues
                                        Thyroid gland Glandular cells
                                        Parathyroid gland Glandular cells
                                        Adrenal gland Glandular cells
                                        Respiratory system
                                        Nasopharynx Respiratory epithelial cells
                                        Bronchus Respiratory epithelial cells
                                        Lung Alveolar cells
                                        Lung Macrophages
                                        Proximal digestive tract
                                        Oral mucosa Squamous epithelial cells
                                        Salivary gland Glandular cells
                                        Esophagus Squamous epithelial cells
                                        Gastrointestinal tract
                                        Stomach 1 Glandular cells
                                        Stomach 2 Glandular cells
                                        Duodenum Glandular cells
                                        Small intestine Glandular cells
                                        Colon Endothelial cells
                                        Colon Glandular cells
                                        Colon Peripheral nerve/ganglion
                                        Rectum Glandular cells
                                        Liver & Gallbladder
                                        Liver Hepatocytes
                                        Liver Cholangiocytes
                                        Gallbladder Glandular cells
                                        Pancreas
                                        Pancreas Exocrine glandular cells
                                        Pancreas Pancreatic endocrine cells
                                        Kidney & Urinary bladder
                                        Kidney Cells in glomeruli
                                        Kidney Cells in tubules
                                        Urinary bladder Urothelial cells
                                        Male reproductive system
                                        Testis Cells in seminiferous ducts
                                        Testis Leydig cells
                                        Epididymis Glandular cells
                                        Prostate Glandular cells
                                        Seminal vesicle Glandular cells
                                        Breast and female reproductive system
                                        Breast Adipocytes
                                        Breast Glandular cells
                                        Breast Myoepithelial cells
                                        Vagina Squamous epithelial cells
                                        Cervix Squamous epithelial cells
                                        Cervix Glandular cells
                                        Endometrium 1 Glandular cells
                                        Endometrium 1 Cells in endometrial stroma
                                        Endometrium 2 Glandular cells
                                        Endometrium 2 Cells in endometrial stroma
                                        Fallopian tube Glandular cells
                                        Ovary Follicle cells
                                        N/A
                                        Ovary Ovarian stroma cells
                                        Placenta Trophoblastic cells
                                        Placenta Decidual cells
                                        N/A
                                        Muscle tissues
                                        Heart muscle Cardiomyocytes
                                        Skeletal muscle Myocytes
                                        Smooth muscle Smooth muscle cells
                                        Connective & Soft tissue
                                        Adipose tissue Adipocytes
                                        Soft tissue 1 Peripheral nerve
                                        Soft tissue 1 Chondrocytes
                                        Soft tissue 1 Fibroblasts
                                        Soft tissue 2 Fibroblasts
                                        Soft tissue 2 Chondrocytes
                                        N/A
                                        Soft tissue 2 Peripheral nerve
                                        Skin
                                        Skin 1 Fibroblasts
                                        Skin 1 Keratinocytes
                                        Skin 1 Langerhans
                                        Skin 1 Melanocytes
                                        Skin 2 Epidermal cells
                                        Bone marrow & Lymphoid tissues
                                        Appendix Glandular cells
                                        Appendix Lymphoid tissue
                                        Bone marrow Hematopoietic cells
                                        Lymph node Germinal center cells
                                        Lymph node Non-germinal center cells
                                        Tonsil Germinal center cells
                                        Tonsil Non-germinal center cells
                                        Tonsil Squamous epithelial cells
                                        Spleen Cells in white pulp
                                        Spleen Cells in red pulp
                                         
                                        Staining summaryi

                                        Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.

                                        Most normal tissues showed weak to moderate cytoplasmic and/or nuclear positivity. Bone marrow, glial cells, islets of Langerhans and soft tissues were negative.

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