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                                          TISSUE PRIMARY DATA URINARY BLADDER Show tissue menu
                                          ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BLOOD VESSEL BONE MARROW BREAST BRONCHUS CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON
                                          DUODENUM ENDOMETRIUM EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MIDBRAIN
                                          NASOPHARYNX ORAL MUCOSA OVARY PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN
                                          SMALL INTESTINE SMOOTH MUSCLE SOFT TISSUE SPINAL CORD SPLEEN STOMACH TESTIS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA
                                          ANTIBODIES
                                          AND
                                          VALIDATION
                                          Dictionary
                                          Urinary bladder
                                          Tissue proteome
                                          Tissue methods
                                          URINARY BLADDER - Expression summary
                                          Protein expression
                                          Urinary bladderi

                                          On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

                                          h
                                          m
                                          l
                                          n
                                          Urothelial cells: High
                                          RNA expressioni

                                          A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

                                          Scroll down to view mRNA expression data in more detail.

                                          Consensus:39.0 nTPM
                                          HPA:35.0 nTPM
                                          GTEx:39.0 nTPM
                                          FANTOM5:17.7 Scaled Tags Per Million
                                          URINARY BLADDER - SINGLE CELL RNA EXPRESSION
                                          Explore single cell type data
                                          Schwann cellsUrothelial cellsSmooth muscle cellsVascular endothelial cellsLymphatic endothelial cellsPericytesVascular smooth muscle cellsFibroblastsMast cellsNeutrophilsMonocytesMacrophagesT-cellsInnate lymphoid cellsB-cellsPlasma cellsNK-cells050100150200250300nCPM

                                          URINARY BLADDER - Antibody stainingi

                                          Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells. Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.

                                          Ascending and descending describe two types of gradient, based on difference in staining intensity between enterocytes in crypts and apical enterocytes.

                                          Ascending - the staining intensity is stronger in apical enterocytes (towards the lumen) compared to enterocytes in the crypts (gland based)

                                          Descending - the staining is weaker in apical enterocytes compared to enterocytes in crypts

                                          Antibody HPA034489Antibody HPA034490
                                          Urothelial cells MediumHigh





                                          URINARY BLADDER - HPA RNA-seqi

                                          The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.

                                          Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.

                                          Average nTPMi

                                          Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

                                          35.0
                                          overview
                                          Male, age 74
                                          Urinary bladder sample 264
                                          nTPM: 32.5
                                          Cell types%
                                          Urothelial cells:
                                          5

                                          Smooth muscle cells:
                                          60

                                          Fibroblasts:
                                          20

                                          Endothelial cells:
                                          10

                                          Other cell types:
                                          5

                                          overview
                                          Male, age 80
                                          Urinary bladder sample 265
                                          nTPM: 32.3
                                          Cell types%
                                          Urothelial cells:
                                          10

                                          Smooth muscle cells:
                                          45

                                          Fibroblasts:
                                          15

                                          Endothelial cells:
                                          10

                                          Other cell types:
                                          20

                                          N/A
                                          Female, age 0.1
                                          Urinary bladder sample 1597
                                          nTPM: 32.1
                                          N/A
                                          Female, age 0.1
                                          Urinary bladder sample 1598
                                          nTPM: 43.3

                                          URINARY BLADDER - GTEx RNA-seqi

                                          RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

                                          Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

                                          Max subtype nTPMi

                                          Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

                                          39.0
                                          GTEx sample id Sample description nTPM
                                          27.237.248.917.979.7010203040506070
                                          27.237.248.917.979.7010203040506070
                                          Bladder
                                          Average nTPM: 39.0
                                          Samples: 77

                                          Max nTPM: 79.7
                                          Min nTPM: 17.9
                                          Std nTPM: 14.4
                                          Median nTPM: 37.2
                                          GTEX-QDVJ-1526-SM-GPI84 50-59 years, male 79.7
                                          GTEX-P4QS-1926-SM-GQ1BY 60-69 years, male 75.5
                                          GTEX-SE5C-1026-SM-4BRUG 40-49 years, female 69.2
                                          GTEX-OOBJ-1926-SM-GRR1P 60-69 years, male 67.7
                                          GTEX-SUCS-1226-SM-GPI9A 70-79 years, male 64.3
                                          GTEX-QEL4-1826-SM-EZ6KU 50-59 years, male 62.1
                                          GTEX-TMMY-1526-SM-4DXST 40-49 years, female 61.8
                                          GTEX-Q2AH-1326-SM-GPRWF 40-49 years, male 59.9
                                          GTEX-PLZ5-1326-SM-GQ1C2 50-59 years, male 58.3
                                          GTEX-OIZF-1926-SM-7PBZS 60-69 years, male 57.5
                                          GTEX-PLZ6-1026-SM-GQ1C8 30-39 years, male 56.8
                                          GTEX-OHPK-1926-SM-H7OF2 50-59 years, female 56.5
                                          GTEX-P4PQ-1926-SM-GRR14 60-69 years, male 55.6
                                          GTEX-T5JC-1126-SM-GPIA1 20-29 years, male 55.0
                                          GTEX-TKQ2-0526-SM-GRR15 50-59 years, male 53.4
                                          GTEX-S32W-1126-SM-4AD5V 50-59 years, female 52.9
                                          GTEX-QEG5-2326-SM-GRR2Z 20-29 years, male 52.2
                                          GTEX-S4P3-0826-SM-H7OF3 50-59 years, female 49.6
                                          GTEX-NPJ8-1126-SM-GNTAI 40-49 years, male 49.1
                                          GTEX-U4B1-1226-SM-4DXT7 40-49 years, male 48.9
                                          GTEX-T2IS-2526-SM-GRR23 20-29 years, female 48.8
                                          GTEX-RWS6-1426-SM-GPRWQ 60-69 years, female 48.1
                                          GTEX-OXRK-1926-SM-GRR1N 50-59 years, female 47.2
                                          GTEX-Q734-1226-SM-GRR21 40-49 years, female 46.4
                                          GTEX-U3ZM-0826-SM-4DXU6 40-49 years, male 43.0
                                          GTEX-R55C-1226-SM-GOQY7 40-49 years, male 42.4
                                          GTEX-QDVN-1426-SM-GPRWL 50-59 years, male 41.7
                                          GTEX-QV31-0926-SM-GQ1C6 30-39 years, male 41.5
                                          GTEX-QV44-1426-SM-GPI8D 50-59 years, male 41.4
                                          GTEX-R55G-1326-SM-HAUYU 40-49 years, female 41.4
                                          GTEX-P78B-2126-SM-GQ1C3 40-49 years, female 40.9
                                          GTEX-OIZH-1926-SM-GPRXO 50-59 years, male 40.6
                                          GTEX-OHPM-1926-SM-H7OG1 50-59 years, male 39.7
                                          GTEX-S4Q7-0926-SM-4AD5D 20-29 years, male 39.1
                                          GTEX-QDT8-2826-SM-GOQYY 30-39 years, female 38.5
                                          GTEX-QMRM-1326-SM-HAUYS 50-59 years, male 38.1
                                          GTEX-RM2N-1026-SM-GOQY8 50-59 years, male 37.7
                                          GTEX-P4QT-1926-SM-HAUYQ 50-59 years, female 37.6
                                          GTEX-QCQG-0826-SM-GPI8H 50-59 years, female 37.2
                                          GTEX-S95S-0626-SM-EZ6L8 60-69 years, male 34.5
                                          GTEX-OIZI-1926-SM-H7OGY 40-49 years, male 33.7
                                          GTEX-PW2O-1026-SM-GPRWA 20-29 years, male 33.4
                                          GTEX-REY6-2026-SM-GPRYL 60-69 years, male 32.3
                                          GTEX-S3XE-1226-SM-4AD4L 50-59 years, male 32.1
                                          GTEX-RWSA-2126-SM-H7OG7 40-49 years, male 31.9
                                          GTEX-RN64-2426-SM-EZ6L2 50-59 years, male 31.5
                                          GTEX-T8EM-1726-SM-GPRWO 40-49 years, male 31.1
                                          GTEX-QXCU-2226-SM-GPI87 50-59 years, male 30.7
                                          GTEX-OHPL-1926-SM-HAV18 60-69 years, female 30.0
                                          GTEX-T6MN-2226-SM-EVYAM 50-59 years, male 30.0
                                          GTEX-R45C-2426-SM-HL11G 60-69 years, female 29.4
                                          GTEX-O5YT-1926-SM-H6Q82 20-29 years, male 28.1
                                          GTEX-S33H-1926-SM-EYYVH 30-39 years, male 28.0
                                          GTEX-Q2AI-1026-SM-GRR3I 40-49 years, male 27.7
                                          GTEX-N7MT-1826-SM-GQ1C9 60-69 years, female 27.5
                                          GTEX-QLQ7-1226-SM-GOQYE 60-69 years, male 27.4
                                          GTEX-QLQW-0826-SM-H7OG2 30-39 years, male 27.3
                                          GTEX-R53T-1426-SM-H7OG3 50-59 years, female 27.2
                                          GTEX-T6MO-0926-SM-GPRWN 40-49 years, female 27.2
                                          GTEX-RUSQ-1326-SM-GQ1EA 50-59 years, male 27.1
                                          GTEX-P44H-2226-SM-E9U4P 40-49 years, male 26.7
                                          GTEX-OOBK-1926-SM-HAUZL 40-49 years, male 26.5
                                          GTEX-P4PP-1926-SM-HAUZM 30-39 years, female 25.3
                                          GTEX-PWCY-1126-SM-H7OGX 20-29 years, female 24.9
                                          GTEX-SNOS-0526-SM-4DM54 40-49 years, male 24.9
                                          GTEX-T5JW-1026-SM-EZ6LR 20-29 years, female 24.8
                                          GTEX-N7MS-2126-SM-GRR2X 60-69 years, male 24.6
                                          GTEX-QEG4-2126-SM-GQ1CE 30-39 years, male 24.4
                                          GTEX-POMQ-0926-SM-H6Q6H 20-29 years, female 23.6
                                          GTEX-S7SF-1126-SM-GQ1CH 20-29 years, female 23.6
                                          GTEX-PX3G-1926-SM-GQ1ED 20-29 years, female 23.2
                                          GTEX-PWN1-1926-SM-HAUZN 40-49 years, female 22.8
                                          GTEX-U3ZN-1226-SM-4DXUD 30-39 years, female 22.4
                                          GTEX-RNOR-2126-SM-EXURR 50-59 years, female 22.0
                                          GTEX-SNMC-0826-SM-4DM66 20-29 years, male 20.0
                                          GTEX-S4UY-0926-SM-4AD6O 40-49 years, female 18.7
                                          GTEX-U3ZH-0826-SM-H6Q7I 30-39 years, male 17.9
                                          Show allShow less

                                          URINARY BLADDER - FANTOM5 CAGEi

                                          RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

                                          Max subtype Scaled Tags Per Millioni

                                          Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

                                          17.7
                                          FANTOM5 sample id Sample description Scaled Tags Per Million
                                          Bladder
                                          Scaled Tags Per Million: 17.7
                                          FF:10011-101C2 55,58,79 years, mixed 17.7

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