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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
Annotated protein expressioni
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA015641
Nuclear staining in most tissues and cells. Additional cytoplasmic staining in a few tissues e.g. squamous and glandular epithelia. Chief cells of stomach and neuronal cells of CNS showed distinct cytoplasmic immunoreactivity while strong nuclear staining was observed in cells of ductus seminiferus in the testis and Purkinje cells of the cerebellum. Distinct staining in reaction centers in tonsil, other leucocytes were virtually negative.
CAB008108
Most of the normal tissues displayed moderate nuclear positivity which in a few cases was accompanied with cytoplasmic staining. Strong nuclear immunoreactivity was observed in cells of seminiferus duct and CNS. Basal cells of surface epithelium, smooth and skeletal muscle cells showed strong cytoplasmic staining.
The Human Protein Atlas project is funded
