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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
Annotated protein expressioni
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA003303
Most epithelial cells displayed weak cytoplasmic immunoreactivity. Stronger staining was observed in placental decidual cells, breast and neuronal cells. Cells in seminiferus ducts showed additional nuclear staining.
HPA028872
Most normal tissues displayed weak to moderate cytoplasmic and nuclear staining with additional nuclear membrane staining in some cases. Large intestine, exocrine pancreas, cells in seminiferous ducts of testis and peripheral nerves displayed strong cytoplasmic staining.
HPA030445
Most of the normal tissues displayed weak to moderate nuclear and cytoplasmic positivity. The lung, liver, pancreas, neuronal cells and spleen were generally negative.
CAB073417
Most normal tissues showed weak to moderate nuclear, cytoplasmic and membranous staining. Intestinal tract displayed strong membranous and cytoplasmic positivity. The neuropil showed strong positivity. Squamous epithelia showed moderate to strong nuclear staining. Liver, cells in glomeruli, Leydig cells, spleen and muscle myocytes were negative.
The Human Protein Atlas project is funded
