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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
Annotated protein expressioni
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA021259
Spermatids and enteroendocrine cells showed strong cytoplasmic staining. Squamous epithelia and salivary glands exhibited moderate membranous immunoreactivity. Lymphoid cells outside reaction centra and heart muscle displayed moderate cytoplasmic staining. Malignant lymphomas showed moderate cytoplasmic staining while cases of malignant melanomas, urothelial cancers and squamous cell carcinomas displayed moderate membranous immunoreactivity. Remaining normal and malignant tissues were generally negative.
HPA021260
Most normal cells were weakly stained or negative. Gastrointestinal tract, liver, exocrine pancreas, placenta, male genitals and neuronal cells showed moderate to strong cytoplasmic positivity.
HPA021271
Squamous epithelia, parts of the gastrointestinal tract, renal tubules, placenta and muscle cells showed moderate cytoplasmic staining. Cholangiocarcinomas, thyroid and skin cancers exhibited weak to moderate cytoplasmic staining. Remaining normal and malignant tissues were weakly stained or negative.
The Human Protein Atlas project is funded
