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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
Annotated protein expressioni
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA031999
Strong cytoplasmic and nuclear staining was observed in subset of cells in red pulp of spleen. Follicle cells in ovary and neurons in hippocampus displayed weak cytoplasmic staining. Squamous cells in esophagus and vagina showed weak membrane positivity. Other normal tissues were negative.
HPA032017
A subset of immune cells showed strong cytoplasmic staining. Remaining normal tissues were negative.
CAB016268
Inflammatory cells were distinctly stained. Hematopoietic cells and a subset of cells in intestinal tract, seminal vesicle and cells in red pulp of spleen showed strong cytoplasmic staining. A subset of cells in most squamous epithelia showed weak cytoplasmic and membranous positivity. Remaining normal tissues were negative.
CAB080545
Moderate to strong membranous and cytoplasmic staining was observed mainly in subsets of immune cells, squamous epithelial cells, neuronal and prostate glandular cells. Most remaining normal cells were weakly stained or negative.
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