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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
Annotated protein expressioni
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA046404
Lung macrophages, Kupffer cells in liver, macrophages in red pulp of spleen along with subset of cells in lymphoid tissues, hematopoietic cells and cells in seminiferus ducts of testis displayed strong cytoplasmic staining. Respiratory epithelia, gall bladder, fallopian tube, Purkinje cells, seminal vesicle and decidual cells showed weak to moderate positivity. Remaining normal tissues were negative.
HPA051974
Strong cytoplasmic positivity was observed in red pulp of spleen, hematopoietic cells, Kupffer cells and macrophages. Renal tubules and peripheral nerve were moderately stained. Subset of neuronal cells in cerebral cortex showed moderate nuclear staining. Alveolar macrophages exhibited moderate cytoplasmic and membranous positivity. Remaining normal tissues were negative.
CAB002432
Strong immunoreactivity in macrophages e.g. Kupfer cells in the liver, Hofbauer cells in placenta and inflammatory macrophages in other tissues. Other cells were virtually negative.
The Human Protein Atlas project is funded
