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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
Annotated protein expressioni
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA023372
Moderate to strong cytoplasmic positivity was observed in most normal tissues. The liver, islet cells of pancreas, prostate, subset of cells in CNS, spleen and lymph node were negative or weakly stained.
HPA023382
Most normal tissues displayed moderate cytoplasmic positivity. Strong staining was observed in placenta and purkinje cells. The liver, glial cells and subset of lymphoid cells were weakly stained.
HPA024768
Purkinje cells and placenta exhibited strong cytoplasmic expression. Strong apical staining was observed in ciliated cells in fallopian tube. CNS was weakly stained. The remaining normal tissues generally showed moderate cytoplasmic staining often combined with nuclear positivity.