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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
No data
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
8.5
nTPM
HPA Brain:
50.0
nTPM
GTEx:
8.5
nTPM
Pig:
20.7
nTPM
Mouse:
44.8
nTPM
Allen mouse:
8.7
Expression energy
MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
50.0
Sample id
Sample description
nTPM
Cuneiform nucleus nTPM: 47.0
2219
Male, age 76, both hemispheres
65.5
2586
Male, age 75, left hemisphere
57.5
1827
Male, age 72, unknown
51.1
2666
Male, age 74, left hemisphere
49.9
2828
Female, age 72, unknown
46.0
1833
Male, age 53, unknown
45.4
2411
Female, age 72, unknown
45.2
1830
Male, age 51, unknown
37.5
2019
Male, age 18, unknown
36.8
1870
Female, age 42, unknown
34.7
Dorsal raphe nucleus nTPM: 39.7
2047
Male, age 72, unknown
46.3
2298
Female, age 72, unknown
42.3
1828
Male, age 53, unknown
41.8
2750
Male, age 76, both hemispheres
36.2
2016
Female, age 72, unknown
31.8
Inferior colliculus nTPM: 46.0
2849
Male, age 72, unknown
53.3
1848
Female, age 42, unknown
45.8
1890
Male, age 53, unknown
44.1
2097
Female, age 72, unknown
40.5
Median raphe nucleus nTPM: 50.0
2220
Male, age 76, midline
50.0
Periaquaductal grey, anterior nTPM: 40.8
1795
Male, age 51, unknown
45.3
1947
Male, age 18, unknown
44.0
2502
Female, age 75, unknown
33.2
Periaquaductal grey, dorsal nTPM: 45.1
1831
Male, age 72, unknown
51.5
1840
Male, age 53, unknown
45.7
2464
Female, age 72, unknown
43.4
2850
Male, age 76, both hemispheres
39.7
Periaquaductal grey, lateral nTPM: 37.5
2053
Male, age 18, unknown
42.7
2140
Male, age 76, both hemispheres
39.6
2272
Male, age 74, both hemispheres
30.3
Pretectal area nTPM: 44.8
1816
Male, age 51, unknown
61.7
1944
Female, age 72, unknown
58.6
2407
Male, age 75, both hemispheres
53.9
2007
Male, age 72, unknown
47.3
1817
Female, age 42, unknown
45.3
2825
Male, age 18, unknown
41.0
2224
Female, age 72, unknown
40.2
1815
Male, age 53, unknown
39.2
2667
Female, age 75, unknown
39.1
2316
Male, age 76, right hemisphere
36.6
2273
Male, age 74, both hemispheres
30.2
Red nucleus nTPM: 37.1
2584
Male, age 75, left hemisphere
52.3
2725
Female, age 75, unknown
40.9
2785
Male, age 18, unknown
40.7
1954
Female, age 42, unknown
37.5
1821
Female, age 72, unknown
37.0
2769
Male, age 72, unknown
36.2
2227
Male, age 72, unknown
36.1
2588
Male, age 74, left hemisphere
34.5
2823
Male, age 76, right hemisphere
33.8
2503
Female, age 72, unknown
33.2
1904
Male, age 53, unknown
33.0
1865
Male, age 51, unknown
30.4
Substantia nigra nTPM: 38.9
1889
Female, age 72, unknown
51.3
1941
Male, age 53, unknown
49.8
2583
Male, age 75, right hemisphere
46.5
1916
Female, age 42, unknown
42.4
2590
Female, age 75, unknown
39.8
2665
Male, age 74, both hemispheres
38.0
1851
Male, age 51, unknown
36.4
2699
Male, age 18, unknown
32.2
2241
Male, age 72, unknown
29.9
2409
Female, age 72, unknown
23.0
Superior colliculus nTPM: 42.1
2087
Female, age 72, unknown
54.5
2668
Female, age 75, unknown
48.5
1895
Male, age 76, right hemisphere
48.2
2664
Male, age 75, both hemispheres
47.8
2261
Male, age 18, unknown
47.1
1796
Male, age 53, unknown
41.6
1839
Male, age 51, unknown
38.6
1913
Female, age 42, unknown
33.3
2587
Male, age 74, left hemisphere
33.0
1995
Male, age 72, unknown
28.7
Ventral tegmental area nTPM: 38.2
2218
Male, age 76, both hemispheres
42.0
1942
Male, age 51, unknown
40.1
1915
Female, age 42, unknown
39.9
2410
Female, age 72, unknown
39.2
2021
Male, age 53, unknown
35.1
2223
Female, age 72, unknown
33.0
MIDBRAIN - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
8.5
GTEx sample id
Sample description
nTPM
Brain - Substantia nigra Average nTPM: 8.5
Samples: 139
Max nTPM: 23.7
Min nTPM: 3.3
Std nTPM: 3.4
Median nTPM: 7.8
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
44.8
Mouse sample
Sample description
nTPM
Midbrain nTPM: 44.8
Samples: 4
Max nTPM: 47.3
Min nTPM: 43.7
Sample A
Male
43.7
Sample B
Male
44.0
Sample C
Female
47.3
Sample D
Female
44.2
MIDBRAIN - Allen Mouse ISHi
In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.
Max subtype Expression energyi
Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.