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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
Annotated protein expressioni
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA017980
Distinct membranous and occasional cytoplasmic immunoreactivity was observed in proximal renal tubuli, seminiferus duct cells, the parathyroid gland, trophoblasts, pancreatic islet cells and basal cells in squamous epithelia. Vessels in the CNS stained strongly. Remaining normal cells were in general negative.
CAB010455
The parathyroid gland, pancreatic islet cells, seminiferous duct cells, proximal renal tubules and the basal layer in squamous epithelia showed distinct cytoplasmic and membranous immunoreactivity. Parts of the intestine and subsets of cells in lymphoid tissue showed moderate membranous staining. Normal tissues in general displayed weak positivity or were negative.