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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
Annotated protein expressioni
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA058363
Fraction of cells in exocrine pancreas and renal tubules displayed moderate cytoplasmic staining. Gastrointestinal tract showed weak to moderate luminal membranous positivity. Weak cytoplasmic staining was observed in placental trophoblasts. Neuropil was distinctly stained. Neurons exhibited weak to moderate nuclear immunoreactivity. Remaining normal tissues were negative.
HPA059577
Prostate showed moderate membranous staining. Fraction of neuronal cells displayed moderate cytoplasmic and nuclear positivity. Stomach and renal tubules showed moderate to strong cytoplasmic and membranous staining. Pancreas and urothelial cells were weakly stained. Moderate cytoplasmic immunoreactivity was observed in ovarian follicles, endocervical glands and megakaryocytes. Remaining normal tissue were negative.