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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
Annotated protein expressioni
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA018859
Normal tissues displayed moderate to strong nuclear positivity often combined with cytoplasmic staining. Cells in CNS were weakly stained or negative.
HPA019938
Weak to moderate nuclear positivity was oserved in most normal tissues. Glandular cells in intestine, renal tubules and urothelium were strongly stained. Squamous epithelia were generally negative.
HPA025230
Most normal tissues showed moderate nuclear positivity, combined with a few cases of cytoplasmic staining. Strong straining was observed in gall bladder, exocrine pancreas, adrenal cortex and renal tubules. Myocytes and liver were weakly stained or negative.
CAB002679
Cells in gastrointestinal tract, squamous epithelium, gall bladder, exocrine pancreas, urothelium and male genitalia exhibited moderate to strong granular cytoplasmic staining. Liver, cells in CNS and lymphoid tissues were mainly negative.
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