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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
Annotated protein expressioni
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA043564
Gastrointestinal tract showed strong cytoplasmic and membranous positivity while fraction of non-germinal center cells of lymphoid tissues displayed strong cytoplasmic and nuclear staining. Respiratory epithelia, gall bladder, adrenal gland, subsets of cells in seminiferus ducts of testis, breast and hematopoietic cells were moderately stained. Additional nuclear positivity was observed in stomach, neuronal cells, placental trophoblasts and urothelial cells. Remaining normal cells were weakly stained or negative.
HPA048267
Most normal tissues showed weak to moderate cytoplasmic staining with additional nuclear positivity in many cases. Glandular cells in stomach, small intestine and myocytes in skeletal muscle showed strong immunoreactivity. Skin, lung, soft tissues, lymphoid tissues and glial cells were in general negative.
The Human Protein Atlas project is funded
