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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
Annotated protein expressioni
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA047217
Cells in seminiferus ducts of testis and post-menopausal endometrial gland displayed strong cytoplasmic and membranous staining. Germinal center cells of tonsil exhibited strong cytoplasmic staining. Weak to moderate cytoplasmic immunoreactivity was observed in gastrointestinal tract, gall bladder, exocrine pancreas, breast, smooth and skeletal muscle cells. Neuronal cells displayed moderate cytoplasmic and nucleolar staining. Remaining normal cells were negative.
HPA054023
Prostate displayed strong cytoplasmic staining with additional nuclear positivity in Leydig cells. Moderate cytoplasmic or membranous staining was observed in adrenocortical cells, respiratory epithelia, Purkinje cells, stomach, intestine, gall bladder, renal tubules, ovarian follicles, salivary gland and myocytes. Remaining normal tissues were weakly stained or negative.
CAB079950
Cytoplasmic positivity of varying intensity was observed in a majority of normal tissues. A few tissues, e.g. testis and adrenal gland, showed additional nuclear positivity.