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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
Annotated protein expressioni
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA023904
Most normal tissues showed moderate cytoplasmic immunoreactivity. Purkinje cells, urinary bladder and trophoblasts were strongly stained.
HPA024010
Most normal tissues showed weak to moderate cytoplasmic staining. The intestine showed strong membranous and cytoplasmic staining. Neuronal cells showed moderate nuclear and cytoplasmic staining. Liver, exocrine pancreas and glial cells were negative.
HPA025960
Most of the normal tissues displayed moderate to strong cytoplasmic and membranous positivity. Membranous staining was for example observed in the salivary gland and hepatic bile ducts. Hepatocytes, muscle cells, cells in the CNS, ovarian and endometrial stroma were negative.
CAB017037
Moderate to strong cytoplasmic and nuclear immunoreactivity was observed in most normal tissues. Additional membranous positivity was for example observed in breast, the intestine and renal tubules. Myocytes were negative.
The Human Protein Atlas project is funded
