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The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.
The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".
Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.
Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.
& Survival analysisi
Kaplan-Meier plots summarize results from analysis of correlation between mRNA expression level and patient survival. Patients were divided based on level of expression into one of the two groups "low" (under cut off) or "high" (over cut off). X-axis shows time for survival (years) and y-axis shows the probability of survival, where 1.0 corresponds to 100 percent.
EEF1A1 is not prognostic in Pancreatic Adenocarcinoma (TCGA)
Stage:
Survival analysis
Current cut offi
Current cut-off shows the cut-off (FPKM) currently selected. It may be changed manually. When the current cut-off is changed, the vertical dashed line indicating cut-off, the interactive survival scatter plot and the Kaplan-Meier curve will be automatically adjusted to show results accordingly.
:
Best expression cut offi
Based on the FPKM value of each gene, patients were classified into two groups and association between prognosis (survival) and gene expression (FPKM) was examined. The best expression cut-off refers the FPKM value that yields maximal difference with regard to survival between the two groups at the lowest log-rank P-value. Best expression cut-off was selected based on survival analysis .
When clicking on this number, the vertical dashed line indicating cut-off, the interactive survival plot, and the Kaplan-Meier curve will be adjusted to show results based on the best expression cut-off.
Median expression refers to the median FPKM value calculated based on the gene expression (FPKM) data from all patients in this dataset. When clicking on this number, the vertical dashed line indicating cut-off, the interactive survival plot, and the Kaplan-Meier curve will be adjusted to show results based on the median expression.
Median follow up time refers to the median time (years) after diagnosis with this type of cancer, based on clinical data from all patients in this dataset.
: N/A
P scorei
Log-rank P value for Kaplan-Meier plot showing results from analysis of correlation between mRNA expression level and patient survival.
N/A
5-year survival highi
5-year survival for patients with higher expression than the expression cutoff.
For melanoma and glioma, 3-year survival is shown.
N/A
5-year survival lowi
5-year survival for patients with lower expression than the expression cutoff.
For melanoma and glioma, 3-year survival is shown.
N/A
TCGA RNA samplesi
RNA-seq data is reported as average FPKM (number Fragments Per Kilobase of exon per Million reads), generated by the The Cancer Genome Atlas (TCGA) .
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. FPKM values of the individual samples are presented next to the box plot.
Average TPM
4995.4
Number of samples
176
Samples
Sample
Description
TPM
TCGA-IB-7887-01A
0 years, female, white, stage:Stage IIB, dead, 110 days
12175.1
TCGA-HZ-8005-01A
0 years, male, white, stage:Stage IIB, dead, 120 days
9681.9
TCGA-Z5-AAPL-01A
0 years, female, white, stage:Stage IIA, alive, 467 days
9515.6
TCGA-IB-7644-01A
0 years, female, white, stage:Stage IV, dead, 394 days
8922.2
TCGA-RL-AAAS-01A
0 years, female, white, stage:Stage IB, alive, 9 days
7808.3
TCGA-HZ-A9TJ-01A
0 years, male, white, stage:Stage IV, alive, 603 days
7805.9
TCGA-IB-7889-01A
0 years, female, white, stage:Stage IIB, dead, 481 days
7783.5
TCGA-F2-A44G-01A
0 years, female, white, stage:Stage IIB, dead, 233 days
7622.8
TCGA-Q3-A5QY-01A
0 years, male, white, stage:Stage IIB, alive, 416 days
7500.6
TCGA-US-A77J-01A
0 years, female, white, stage:Stage IIB, dead, 568 days
7434.4
TCGA-IB-7886-01A
0 years, male, white, stage:Stage IIB, dead, 123 days
7396.1
TCGA-HZ-8002-01A
0 years, male, white, stage:Stage IIB, dead, 366 days
7066.5
TCGA-LB-A8F3-01A
0 years, female, black or african american, stage:Stage IIA, alive, 379 days
6902.6
TCGA-IB-AAUR-01A
0 years, male, white, stage:Stage IIB, alive, 338 days
6895.1
TCGA-2L-AAQA-01A
0 years, male, white, stage:Stage IIB, dead, 143 days
6858.5
TCGA-XN-A8T5-01A
0 years, female, white, stage:Stage IB, alive, 720 days
6811.5
TCGA-IB-AAUV-01A
0 years, male, white, stage:Stage IIB, alive, 404 days
6785.2
TCGA-XD-AAUH-01A
0 years, female, white, stage:Stage IIB, alive, 395 days
6703.0
TCGA-3A-A9IO-01A
0 years, male, white, stage:'--, alive, 1942 days
6638.1
TCGA-HZ-7920-01A
0 years, male, white, stage:Stage IB, dead, 236 days
6515.5
TCGA-IB-7888-01A
0 years, female, black or african american, stage:Stage IIA, dead, 1332 days
6496.0
TCGA-HZ-8001-01A
0 years, male, white, stage:Stage III, alive, 706 days
6350.9
TCGA-FB-AAPZ-01A
0 years, male, white, stage:Stage IIB, alive, 716 days
6342.2
TCGA-3A-A9IR-01A
0 years, female, white, stage:Stage IB, alive, 1542 days
6317.2
TCGA-2J-AABR-01A
0 years, female, white, stage:Stage IIA, alive, 438 days
6295.1
TCGA-XD-AAUG-01A
0 years, female, white, stage:Stage IV, alive, 420 days
6284.7
TCGA-HZ-7926-01A
0 years, male, black or african american, stage:Stage IIB, dead, 518 days
6234.0
TCGA-IB-A7M4-01A
0 years, male, white, stage:Stage IIB, alive, 483 days
6225.4
TCGA-IB-7649-01A
0 years, female, stage:Stage IIB, dead, 467 days
6218.6
TCGA-F2-7276-01A
0 years, male, white, stage:Stage IIB, dead, 216 days
6157.1
TCGA-HZ-A77P-01A
0 years, male, white, stage:Stage IIB, alive, 330 days
6118.5
TCGA-FB-A5VM-01A
0 years, male, white, stage:Stage IB, dead, 498 days
6101.2
TCGA-2J-AAB9-01A
0 years, female, white, stage:Stage IIB, dead, 627 days
6053.3
TCGA-HZ-7925-01A
0 years, male, white, stage:Stage IIB, dead, 614 days
6044.7
TCGA-F2-7273-01A
0 years, male, black or african american, stage:Stage IIB, dead, 592 days
6001.2
TCGA-FB-AAQ2-01A
0 years, female, white, stage:Stage IIB, dead, 153 days
5954.7
TCGA-FB-AAPU-01A
0 years, female, asian, stage:Stage IIA, dead, 381 days
5930.5
TCGA-FB-AAQ0-01A
0 years, male, white, stage:Stage IIA, dead, 473 days
5922.3
TCGA-3A-A9J0-01A
0 years, male, white, stage:Stage IIB, alive, 743 days
5914.9
TCGA-IB-7654-01A
0 years, male, white, stage:Stage IIB, dead, 476 days
5882.4
TCGA-IB-AAUW-01A
0 years, female, white, stage:Stage IIB, dead, 230 days
5881.2
TCGA-IB-A5SQ-01A
0 years, female, white, stage:Stage IB, dead, 219 days
5835.0
TCGA-HZ-7924-01A
0 years, female, white, stage:Stage IIA, alive, 840 days
5829.4
TCGA-HZ-A49H-01A
0 years, female, white, stage:Stage IIB, alive, 491 days
5783.5
TCGA-2J-AABT-01A
0 years, female, white, stage:Stage IIB, alive, 319 days
5779.1
TCGA-IB-A5ST-01A
0 years, female, white, stage:Stage IIB, alive, 635 days
5773.2
TCGA-3A-A9IJ-01A
0 years, male, white, stage:Stage IB, alive, 1854 days
5670.0
TCGA-XD-AAUI-01A
0 years, female, white, stage:Stage IIB, dead, 366 days
5668.6
TCGA-FB-A78T-01A
0 years, female, white, stage:Stage IIB, dead, 375 days
5656.0
TCGA-HZ-7922-01A
0 years, female, white, stage:Stage IIB, alive, 4 days
5651.4
TCGA-2L-AAQL-01A
0 years, male, white, stage:Stage IIB, dead, 292 days
5649.9
TCGA-2J-AAB8-01A
0 years, male, white, stage:Stage IIB, alive, 80 days
5629.8
TCGA-3A-A9IX-01A
0 years, male, white, stage:Stage IA, alive, 1037 days
5607.3
TCGA-3E-AAAZ-01A
0 years, male, white, stage:Stage IIA, dead, 2182 days
5573.8
TCGA-IB-7645-01A
0 years, female, stage:Stage IIB, dead, 1502 days
5572.1
TCGA-IB-7897-01A
0 years, female, white, stage:Stage IIB, dead, 486 days
5561.7
TCGA-3A-A9I5-01A
0 years, male, white, stage:'--, alive, 1794 days
5542.8
TCGA-FB-AAPP-01A
0 years, male, white, stage:Stage IIB, dead, 485 days
5532.2
TCGA-IB-AAUS-01A
0 years, female, white, stage:Stage IIB, alive, 225 days
5526.2
TCGA-IB-7893-01A
0 years, male, white, stage:Stage IIA, dead, 117 days
5490.0
TCGA-2J-AABA-01A
0 years, male, white, stage:Stage IIB, dead, 607 days
5484.0
TCGA-IB-AAUP-01A
0 years, male, white, stage:Stage IIB, alive, 431 days
5476.3
TCGA-FB-A4P6-01A
0 years, male, white, stage:Stage IIB, alive, 767 days
5456.5
TCGA-IB-7891-01A
0 years, female, white, stage:Stage IIB, dead, 913 days
5408.4
TCGA-IB-7885-01A
0 years, female, white, stage:Stage IIB, alive, 1257 days
5397.2
TCGA-FB-AAQ3-01A
0 years, female, white, stage:Stage IIB, dead, 31 days
5358.8
TCGA-H6-A45N-01A
0 years, female, white, stage:Stage IIB, dead, 397 days
5331.0
TCGA-2J-AABK-01A
0 years, male, white, stage:Stage IIB, alive, 484 days
5284.8
TCGA-FB-AAPQ-01A
0 years, male, white, stage:Stage IIB, dead, 1130 days
5269.9
TCGA-IB-7890-01A
0 years, male, stage:Stage IB, dead, 598 days
5268.2
TCGA-IB-AAUQ-01A
0 years, male, white, stage:Stage IIB, dead, 183 days
5236.6
TCGA-F2-A44H-01A
0 years, male, white, stage:Stage IIA, alive, 586 days
5233.3
TCGA-IB-AAUT-01A
0 years, male, white, stage:Stage IIB, alive, 287 days
5179.6
TCGA-RB-AA9M-01A
0 years, male, white, stage:Stage IIB, alive, 286 days
5128.5
TCGA-HZ-A49G-01A
0 years, female, white, stage:Stage IIB, alive, 660 days
5109.1
TCGA-HZ-7923-01A
0 years, male, white, stage:Stage IIA, alive, 314 days
5097.1
TCGA-S4-A8RO-01A
0 years, female, white, stage:Stage IIB, alive, 525 days
5081.3
TCGA-IB-7652-01A
0 years, female, asian, stage:Stage IIB, alive, 1116 days
5078.9
TCGA-H8-A6C1-01A
0 years, male, white, stage:Stage IIA, alive, 671 days
5062.3
TCGA-Q3-AA2A-01A
0 years, female, white, stage:Stage IB, alive, 95 days
5047.3
TCGA-IB-A6UG-01A
0 years, male, white, stage:Stage IIB, dead, 41 days
5041.7
TCGA-2J-AABP-01A
0 years, female, white, stage:Stage IIB, alive, 463 days
5034.4
TCGA-HZ-8519-01A
0 years, male, white, stage:Stage IA, alive, 454 days
5016.7
TCGA-3E-AAAY-01A
0 years, male, white, stage:Stage IIB, alive, 2285 days
4972.7
TCGA-IB-7651-01A
0 years, female, white, stage:Stage IIB, dead, 603 days
4969.7
TCGA-XD-AAUL-01A
0 years, male, white, stage:Stage IIA, alive, 498 days
4964.1
TCGA-HZ-7919-01A
0 years, female, white, stage:Stage IIB, dead, 593 days
4921.1
TCGA-HZ-A8P1-01A
0 years, male, white, stage:Stage IB, alive, 7 days
4878.9
TCGA-HZ-7918-01A
0 years, male, white, stage:Stage IIB, alive, 969 days
4877.1
TCGA-US-A77E-01A
0 years, male, white, stage:Stage IIB, dead, 430 days
4863.6
TCGA-S4-A8RP-01A
0 years, female, white, stage:Stage IIB, dead, 702 days
4836.8
TCGA-2J-AAB1-01A
0 years, male, white, stage:Stage IIB, dead, 66 days
4823.9
TCGA-FB-AAQ6-01A
0 years, male, white, stage:Stage IA, dead, 244 days
4813.6
TCGA-3A-A9IC-01A
0 years, female, white, stage:Stage IIB, dead, 738 days
4779.2
TCGA-XN-A8T3-01A
0 years, male, white, stage:Stage IB, alive, 951 days
4776.1
TCGA-2J-AAB4-01A
0 years, male, white, stage:Stage IIB, alive, 729 days
4756.0
TCGA-3A-A9IB-01A
0 years, female, white, stage:Stage IIB, dead, 224 days
4690.5
TCGA-HV-AA8V-01A
0 years, male, asian, stage:Stage IIB, alive, 920 days
4689.6
TCGA-HZ-8636-01A
0 years, female, white, stage:Stage IV, dead, 545 days
4667.8
TCGA-FB-AAQ1-01A
0 years, male, white, stage:Stage IIB, dead, 123 days
4609.2
TCGA-HZ-8638-01A
0 years, female, white, stage:Stage IA, dead, 151 days
4604.3
TCGA-FB-AAPS-01A
0 years, female, white, stage:Stage IIB, alive, 228 days
4591.8
TCGA-2J-AABI-01A
0 years, female, white, stage:Stage IIA, alive, 969 days
4573.6
TCGA-HV-A5A4-01A
0 years, female, asian, stage:Stage IIA, alive, 232 days
4565.6
TCGA-2J-AAB6-01A
0 years, male, white, stage:Stage IIA, dead, 293 days
4564.8
TCGA-IB-A5SO-01A
0 years, male, white, stage:Stage IIB, dead, 365 days
4551.9
TCGA-HZ-A4BH-01A
0 years, male, white, stage:Stage IIB, alive, 194 days
4546.2
TCGA-HZ-A49I-01A
0 years, male, white, stage:Stage IIB, dead, 308 days
4532.8
TCGA-HV-A5A5-01A
0 years, female, asian, stage:Stage IIB, alive, 289 days
4506.5
TCGA-3A-A9I7-01A
0 years, male, black or african american, stage:Stage IIB, alive, 1323 days
4491.6
TCGA-F2-A7TX-01A
0 years, male, white, stage:Stage IIB, dead, 95 days
4487.6
TCGA-2J-AABE-01A
0 years, male, white, stage:Stage IIA, alive, 676 days
4475.8
TCGA-H6-8124-01A
0 years, female, white, stage:Stage IIB, alive, 392 days
4469.1
TCGA-YB-A89D-01A
0 years, male, white, stage:Stage IIB, alive, 350 days
4467.6
TCGA-FB-A4P5-01A
0 years, female, white, stage:Stage IIB, dead, 179 days
4453.9
TCGA-3A-A9IZ-01A
0 years, male, white, stage:Stage IIB, dead, 308 days
4423.9
TCGA-HZ-A77Q-01A
0 years, female, white, stage:Stage IIB, alive, 33 days
4415.2
TCGA-RB-A7B8-01A
0 years, female, white, stage:Stage IIB, dead, 466 days
4397.2
TCGA-US-A774-01A
0 years, female, white, stage:Stage IIB, dead, 695 days
4393.6
TCGA-2L-AAQJ-01A
0 years, female, white, stage:Stage III, dead, 394 days
4363.4
TCGA-2J-AABO-01A
0 years, male, white, stage:Stage IIB, alive, 440 days
4325.4
TCGA-IB-8127-01A
0 years, male, white, stage:Stage IIB, alive, 522 days
4299.4
TCGA-2J-AABU-01A
0 years, male, white, stage:Stage IIB, dead, 277 days
4278.7
TCGA-IB-7646-01A
0 years, male, white, stage:Stage IIB, dead, 145 days
4277.2
TCGA-US-A779-01A
0 years, female, white, stage:Stage IIB, dead, 511 days
4226.5
TCGA-HZ-8315-01A
0 years, female, white, stage:Stage IIA, dead, 299 days
4222.1
TCGA-FB-A7DR-01A
0 years, male, asian, stage:Stage IIA, dead, 353 days
4220.5
TCGA-IB-A6UF-01A
0 years, male, white, stage:Stage IIB, alive, 666 days
4214.4
TCGA-FB-AAPY-01A
0 years, male, white, stage:Stage IIB, dead, 1059 days
4211.5
TCGA-IB-A5SS-01A
0 years, female, white, stage:Stage IIB, dead, 460 days
4208.8
TCGA-FB-A545-01A
0 years, female, white, stage:Stage IIB, dead, 732 days
4152.7
TCGA-HZ-A4BK-01A
0 years, male, white, stage:Stage IIB, alive, 657 days
4099.5
TCGA-IB-A7LX-01A
0 years, male, white, stage:Stage IIB, dead, 250 days
4057.4
TCGA-US-A776-01A
0 years, male, white, stage:Stage IIA, alive, 1216 days
4005.4
TCGA-PZ-A5RE-01A
0 years, female, white, stage:Stage IIB, dead, 470 days
3925.6
TCGA-2J-AABF-01A
0 years, male, white, stage:Stage IIB, dead, 691 days
3916.2
TCGA-3A-A9IU-01A
0 years, male, white, stage:Stage IIB, dead, 458 days
3907.9
TCGA-F2-A8YN-01A
0 years, male, white, stage:Stage IIA, alive, 517 days
3896.5
TCGA-F2-6879-01A
0 years, male, white, stage:Stage IIB, dead, 334 days
3879.3
TCGA-OE-A75W-01A
0 years, male, white, stage:Stage IIA, dead, 267 days
3821.2
TCGA-HZ-A77O-01A
0 years, female, white, stage:Stage IIB, dead, 160 days
3790.4
TCGA-2L-AAQE-01A
0 years, male, white, stage:Stage IIB, dead, 684 days
3749.3
TCGA-2L-AAQI-01A
0 years, male, white, stage:Stage IIB, dead, 103 days
3719.0
TCGA-IB-AAUU-01A
0 years, male, white, stage:Stage IIB, alive, 245 days
3692.9
TCGA-YY-A8LH-01A
0 years, female, white, stage:Stage IIB, alive, 2016 days
3685.5
TCGA-L1-A7W4-01A
0 years, female, white, stage:Stage IIB, dead, 278 days
3637.9
TCGA-HZ-7289-01A
0 years, male, white, stage:Stage IIB, dead, 661 days
3630.3
TCGA-M8-A5N4-01A
0 years, female, stage:Stage IIA, alive, 584 days
3615.0
TCGA-YH-A8SY-01A
0 years, female, white, stage:'--, alive, 388 days
3435.2
TCGA-HZ-8637-01A
0 years, female, white, stage:Stage IIB, dead, 517 days
3424.1
TCGA-HV-A5A6-01A
0 years, female, asian, stage:Stage IIB, dead, 2036 days
3400.2
TCGA-2J-AABH-01A
0 years, male, white, stage:Stage IIA, alive, 1287 days
3394.9
TCGA-3A-A9IN-01A
0 years, female, white, stage:Stage IB, alive, 2084 days
3386.6
TCGA-HZ-8317-01A
0 years, female, white, stage:Stage IIB, dead, 378 days
3382.1
TCGA-3A-A9IL-01A
0 years, female, white, stage:Stage I, alive, 2741 days
3338.9
TCGA-IB-AAUO-01A
0 years, female, white, stage:Stage IIB, dead, 239 days
3337.6
TCGA-3A-A9IH-01A
0 years, female, white, stage:Stage IA, alive, 1021 days
3298.3
TCGA-IB-AAUM-01A
0 years, male, white, stage:Stage IIB, alive, 8 days
3294.7
TCGA-IB-AAUN-01A
0 years, female, white, stage:Stage IB, dead, 144 days
3283.3
TCGA-3A-A9I9-01A
0 years, male, white, stage:Stage IIA, dead, 634 days
3268.7
TCGA-IB-A5SP-01A
0 years, male, white, stage:Stage IIA, alive, 482 days
3232.6
TCGA-2L-AAQM-01A
0 years, male, white, stage:Stage IIB, alive, 1383 days
3184.0
TCGA-3A-A9IV-01A
0 years, female, white, stage:Stage IB, alive, 1103 days
3149.6
TCGA-2J-AABV-01A
0 years, male, white, stage:Stage IIB, dead, 652 days
3107.8
TCGA-3A-A9IS-01A
0 years, male, white, stage:Stage IB, alive, 998 days
3102.3
TCGA-HV-A5A3-01A
0 years, male, asian, stage:Stage IIA, dead, 128 days
3080.7
TCGA-US-A77G-01A
0 years, male, white, stage:Stage IIB, dead, 12 days
3018.8
TCGA-HV-AA8X-01A
0 years, female, asian, stage:Stage IIB, dead, 532 days
2985.5
TCGA-S4-A8RM-01A
0 years, male, white, stage:Stage IIB, alive, 737 days
2881.2
TCGA-IB-8126-01A
0 years, female, white, stage:Stage III, alive, 462 days
2672.4
TCGA-HV-A7OL-01A
0 years, male, asian, stage:Stage IIA, alive, 252 days
2629.3
TCGA-LB-A9Q5-01A
0 years, female, white, stage:Stage IIB, dead, 313 days
2498.3
TCGA-LB-A7SX-01A
0 years, female, black or african american, stage:Stage IIB, dead, 393 days
2445.1
TCGA-HZ-8003-01A
0 years, female, white, stage:Stage IIB, dead, 596 days
2249.0
TCGA-F2-6880-01A
0 years, male, white, stage:Stage IIB, alive, 295 days
2209.2
TCGA-HV-A7OP-01A
0 years, male, asian, stage:Stage IIB, alive, 978 days
The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.
The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".
Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.
Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.
& Survival analysisi
Kaplan-Meier plots summarize results from analysis of correlation between mRNA expression level and patient survival. Patients were divided based on level of expression into one of the two groups "low" (under cut off) or "high" (over cut off). X-axis shows time for survival (years) and y-axis shows the probability of survival, where 1.0 corresponds to 100 percent.
EEF1A1 is not prognostic in Pancreatic Adenocarcinoma (validation)
Stage:
Survival analysis
Current cut offi
Current cut-off shows the cut-off (FPKM) currently selected. It may be changed manually. When the current cut-off is changed, the vertical dashed line indicating cut-off, the interactive survival scatter plot and the Kaplan-Meier curve will be automatically adjusted to show results accordingly.
:
Best expression cut offi
Based on the FPKM value of each gene, patients were classified into two groups and association between prognosis (survival) and gene expression (FPKM) was examined. The best expression cut-off refers the FPKM value that yields maximal difference with regard to survival between the two groups at the lowest log-rank P-value. Best expression cut-off was selected based on survival analysis .
When clicking on this number, the vertical dashed line indicating cut-off, the interactive survival plot, and the Kaplan-Meier curve will be adjusted to show results based on the best expression cut-off.
Median expression refers to the median FPKM value calculated based on the gene expression (FPKM) data from all patients in this dataset. When clicking on this number, the vertical dashed line indicating cut-off, the interactive survival plot, and the Kaplan-Meier curve will be adjusted to show results based on the median expression.
Median follow up time refers to the median time (years) after diagnosis with this type of cancer, based on clinical data from all patients in this dataset.
: N/A
P scorei
Log-rank P value for Kaplan-Meier plot showing results from analysis of correlation between mRNA expression level and patient survival.
N/A
5-year survival highi
5-year survival for patients with higher expression than the expression cutoff.
For melanoma and glioma, 3-year survival is shown.
N/A
5-year survival lowi
5-year survival for patients with lower expression than the expression cutoff.
For melanoma and glioma, 3-year survival is shown.
N/A
TCGA RNA samplesi
RNA-seq data is reported as average FPKM (number Fragments Per Kilobase of exon per Million reads), generated by the The Cancer Genome Atlas (TCGA) .
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. FPKM values of the individual samples are presented next to the box plot.
Average TPM
2919.2
Number of samples
80
Samples
Sample
Description
TPM
DO34961
0 years, male, NA, stage:, dead, 632 days
10918.6
DO33400
0 years, female, NA, stage:, alive, 1043 days
10455.4
DO34785
0 years, female, NA, stage:, alive, 721 days
6054.0
DO34817
0 years, female, NA, stage:, alive, 540 days
5180.2
DO33512
female, NA, stage:, dead, 499 days
4410.2
DO49204
0 years, male, NA, stage:, dead, 156 days
4393.4
DO32863
0 years, male, NA, stage:, dead, 715 days
4349.6
DO49137
0 years, female, NA, stage:, alive, 232 days
4295.9
DO34801
0 years, male, NA, stage:, alive, 626 days
4073.7
DO49166
0 years, female, NA, stage:, alive, 222 days
3999.1
DO49170
0 years, male, NA, stage:, alive, 197 days
3953.2
DO34264
0 years, female, NA, stage:, dead, 1144 days
3943.3
DO49129
0 years, male, NA, stage:, alive, 337 days
3777.5
DO34608
0 years, female, NA, stage:, dead, 709 days
3757.8
DO49076
0 years, male, NA, stage:, dead, 480 days
3672.5
DO33488
0 years, male, NA, stage:, alive, 844 days
3584.4
DO49133
0 years, female, NA, stage:, alive, 188 days
3558.2
DO49168
0 years, male, NA, stage:, alive, 149 days
3540.6
DO49135
0 years, male, NA, stage:, alive, 270 days
3509.1
DO34640
0 years, female, NA, stage:, dead, 287 days
3508.8
DO34448
0 years, female, NA, stage:, dead, 719 days
3495.2
DO32875
0 years, male, NA, stage:, dead, 348 days
3486.5
DO49178
0 years, male, NA, stage:, dead, 27 days
3454.0
DO34240
0 years, male, NA, stage:, dead, 236 days
3392.5
DO34504
0 years, male, NA, stage:, dead, 257 days
3369.9
DO49164
0 years, male, NA, stage:, alive, 272 days
3347.5
DO32829
0 years, female, NA, stage:T2N0MX, dead, 1874 days
3341.0
DO34793
0 years, male, NA, stage:, dead, 427 days
3331.1
DO33168
0 years, female, NA, stage:, dead, 8 days
3255.5
DO49079
0 years, male, NA, stage:, dead, 332 days
3193.9
DO34720
0 years, male, NA, stage:, alive, 555 days
3111.4
DO33128
0 years, male, NA, stage:, dead, 423 days
3080.6
DO49185
0 years, male, NA, stage:, alive, 179 days
2981.8
DO32860
0 years, male, NA, stage:, dead, 1259 days
2946.2
DO49138
0 years, male, NA, stage:, dead, 230 days
2877.1
DO49183
0 years, female, NA, stage:, dead, 429 days
2819.0
DO49080
0 years, male, NA, stage:, alive, 83 days
2817.5
DO34696
0 years, male, NA, stage:, alive, 689 days
2802.7
DO34680
0 years, male, NA, stage:, dead, 99 days
2794.4
DO33984
0 years, male, NA, stage:, alive, 847 days
2782.6
DO33552
0 years, female, NA, stage:, alive, 873 days
2773.2
DO32900
0 years, male, NA, stage:, dead, 768 days
2765.3
DO33392
0 years, male, NA, stage:, alive, 1014 days
2711.9
DO34728
0 years, female, NA, stage:, alive, 508 days
2664.1
DO34600
0 years, male, NA, stage:, dead, 537 days
2659.7
DO49130
0 years, female, NA, stage:, alive, 351 days
2622.9
DO34656
0 years, female, NA, stage:, alive, 834 days
2612.5
DO49127
0 years, female, NA, stage:, alive, 392 days
2572.1
DO49193
0 years, male, NA, stage:, dead, 1 days
2499.8
DO49181
0 years, male, NA, stage:, dead, 1534 days
2488.6
DO33336
0 years, female, NA, stage:, dead, 451 days
2474.3
DO34736
0 years, female, NA, stage:, dead, 203 days
2443.9
DO33368
0 years, male, NA, stage:, dead, 98 days
2388.8
DO34432
0 years, female, NA, stage:, dead, 400 days
2381.7
DO32878
0 years, female, NA, stage:, dead, 260 days
2349.7
DO49078
0 years, male, NA, stage:, dead, 465 days
2345.0
DO49113
0 years, female, NA, stage:, alive, 413 days
2299.0
DO33376
0 years, female, NA, stage:, alive, 909 days
2134.4
DO34809
0 years, female, NA, stage:, dead, 297 days
2072.8
DO34905
0 years, male, NA, stage:, alive, 1142 days
2069.8
DO33344
0 years, male, NA, stage:, dead, 361 days
2050.3
DO34288
0 years, female, NA, stage:, dead, 220 days
2049.1
DO34849
0 years, female, NA, stage:, dead, 272 days
2016.3
DO34616
0 years, female, NA, stage:, alive, 666 days
1943.4
DO33408
0 years, female, NA, stage:, alive, 909 days
1861.9
DO33544
0 years, female, NA, stage:, dead, 412 days
1857.6
DO34312
0 years, female, NA, stage:, dead, 226 days
1693.8
DO33480
0 years, male, NA, stage:, alive, 1054 days
1612.5
DO34368
0 years, female, NA, stage:, dead, 537 days
1517.2
DO49090
0 years, female, NA, stage:, dead, 152 days
1287.9
DO33472
0 years, female, NA, stage:, dead, 388 days
1219.4
DO33600
0 years, female, NA, stage:, alive, 854 days
1197.9
DO49087
0 years, female, NA, stage:, dead, 260 days
1197.1
DO49199
0 years, male, NA, stage:, dead, 1095 days
1145.8
DO49172
0 years, female, NA, stage:, dead, 1021 days
995.1
DO49184
0 years, male, NA, stage:, dead, 455 days
833.5
DO49074
0 years, male, NA, stage:, dead, 168 days
799.0
DO49175
0 years, male, NA, stage:, dead, 414 days
692.0
DO49198
0 years, female, NA, stage:, dead, 251 days
609.3
DO34336
0 years, female, NA, stage:, alive, 743 days
13.2
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PANCREATIC DUCTAL ADENOCARCINOMA - Protein relative expression (CPTAC)
Number of samples
235
Samples
Sample ID
Sample type
nRPX
C3L-00189-04
Normal
0.8
CPT0127290003
Normal
0.7
CPT0123890003
Normal
0.7
CPT0063580003
Normal
0.7
CPT0017130003
Normal
0.7
CPT0089750004
Normal
0.6
CPT0170260004
Normal
0.6
C3L-03632-04
Normal
0.6
CPT0347820002
Normal
0.6
CPT0011540003
Normal
0.6
CPT0078180003
Normal
0.6
CPT0183770004
Normal
0.5
CPT0025760003
Normal
0.5
CPT0238740004
Normal
0.5
CPT0239920004
Normal
0.5
CPT0218220004
Normal
0.5
CPT0198930003
Normal
0.5
CPT0238640004
Normal
0.5
CPT0091680003
Normal
0.5
CPT0237920004
Normal
0.5
CPT0236800004
Normal
0.5
CPT0209650004
Normal
0.4
CPT0238940004
Normal
0.4
CPT0236360004
Normal
0.4
CPT0123460003
Normal
0.4
CPT0208710004
Normal
0.4
CPT0187540004
Normal
0.3
CPT0077810003
Normal
0.3
CPT0208850004
Normal
0.3
CPT0123770003
Normal
0.3
CPT0355190003
Normal
0.3
CPT0347880002
Normal
0.3
CPT0236710004
Normal
0.2
C3N-00709-06
Normal
0.2
C3N-02573-03
Normal
0.2
CPT0237850004
Normal
0.2
CPT0077950003
Normal
0.2
CPT0123670003
Normal
0.2
CPT0162780004
Normal
0.2
CPT0125010003
Normal
0.2
CPT0347760002
Normal
0.2
CPT0108960003
Normal
0.2
CPT0347850002
Normal
0.1
CPT0276030003
Normal
0.1
CPT0248440003
Normal
0.1
CPT0166780004
Normal
0.1
CPT0239140004
Normal
0.1
CPT0124000003
Normal
0.1
CPT0247090003
Tumor
0.1
CPT0238610009
Tumor
0.1
CPT0355200003
Normal
0.0
CPT0124530003
Normal
0.0
CPT0123650003
Tumor
0.0
CPT0198440004
Normal
0.0
CPT0066020003
Normal
0.0
CPT0166760004
Tumor
0.0
CPT0226600004
Tumor
0.0
CPT0093880003
Normal
0.0
CPT0001750003
Normal
0.0
WU-PDA1
Tumor
0.0
CPT0276010003
Tumor
0.0
CPT0092630003
Tumor
0.0
CPT0236340004
Tumor
0.0
CPT0246950003
Normal
0.0
CPT0086210003
Normal
-0.1
CPT0077880003
Normal
-0.1
CPT0064110003
Normal
-0.1
CPT0081360004
Tumor
-0.1
CPT0254680003
Tumor
-0.1
CPT0125130003
Tumor
-0.1
CPT0124610004
Tumor
-0.1
CPT0124360003
Tumor
-0.1
CPT0064090003
Tumor
-0.1
CPT0208840004
Tumor
-0.1
CPT0221240004
Tumor
-0.1
CPT0248620003
Normal
-0.1
CPT0221470005
Tumor
-0.1
CPT0081060004
Tumor
-0.1
CPT0241320005
Tumor
-0.1
CPT0019410004
Tumor
-0.1
CPT0089720003
Tumor
-0.1
CPT0083270003
Tumor
-0.1
CPT0162670004
Normal
-0.1
CPT0221250004
Normal
-0.1
CPT0236560004
Tumor
-0.1
CPT0001730017
Tumor
-0.1
CPT0123990003
Tumor
-0.1
CPT0093860003
Tumor
-0.1
CPT0217700004
Tumor
-0.1
CPT0207990004
Normal
-0.1
CPT0094180003
Tumor
-0.1
CPT0124500004
Tumor
-0.1
CPT0161990005
Tumor
-0.1
CPT0125090003
Tumor
-0.1
CPT0246810003
Tumor
-0.1
CPT0081470004
Tumor
-0.2
CPT0238440005
Tumor
-0.2
CPT0246220004
Normal
-0.2
CPT0014040003
Tumor
-0.2
CPT0063570003
Tumor
-0.2
CPT0347790002
Normal
-0.2
CPT0065570003
Tumor
-0.2
CPT0161770004
Tumor
-0.2
CPT0247040003
Tumor
-0.2
CPT0209640005
Tumor
-0.2
CPT0237840004
Tumor
-0.2
CPT0185920004
Tumor
-0.2
CPT0198700005
Tumor
-0.2
CPT0094740004
Tumor
-0.2
CPT0248590004
Tumor
-0.2
CPT0086190004
Tumor
-0.2
CPT0008800003
Tumor
-0.2
CPT0017040004
Tumor
-0.2
CPT0123860003
Tumor
-0.2
CPT0094230004
Tumor
-0.2
CPT0170240004
Tumor
-0.2
CPT0123440003
Tumor
-0.2
CPT0077790004
Tumor
-0.2
CPT0077930004
Tumor
-0.2
CPT0239910004
Tumor
-0.2
CPT0227930004
Tumor
-0.2
CPT0355180003
Normal
-0.2
CPT0094630004
Tumor
-0.2
CPT0208690004
Tumor
-0.2
CPT0088180004
Tumor
-0.2
CPT0238710004
Tumor
-0.2
CPT0226650004
Tumor
-0.2
CPT0019300004
Tumor
-0.2
CPT0207980005
Tumor
-0.2
CPT0088320003
Tumor
-0.2
CPT0207780004
Tumor
-0.2
CPT0138990003
Normal
-0.2
CPT0094130004
Tumor
-0.2
CPT0208550005
Tumor
-0.2
CPT0123750003
Tumor
-0.2
CPT0025750003
Tumor
-0.2
CPT0239100009
Tumor
-0.2
C3L-00401-04
Normal
-0.2
CPT0246840003
Tumor
-0.3
CPT0226760004
Tumor
-0.3
CPT0237910004
Tumor
-0.3
CPT0109200004
Tumor
-0.3
CPT0248410004
Tumor
-0.3
CPT0139000004
Tumor
-0.3
CPT0235230004
Tumor
-0.3
CPT0162660004
Tumor
-0.3
CPT0238920004
Tumor
-0.3
CPT0218200004
Tumor
-0.3
CPT0187930005
Tumor
-0.3
CPT0224460004
Tumor
-0.3
CPT0226490004
Tumor
-0.3
CPT0109010004
Tumor
-0.3
CPT0203850004
Tumor
-0.3
CPT0063970004
Tumor
-0.3
CPT0077860003
Tumor
-0.3
CPT0247000003
Normal
-0.3
CPT0162760003
Tumor
-0.3
CPT0064520004
Tumor
-0.3
CPT0065640003
Tumor
-0.3
CPT0237270005
Tumor
-0.3
CPT0078160004
Tumor
-0.3
CPT0064570003
Normal
-0.3
CPT0091660003
Tumor
-0.3
CPT0000250017
Tumor
-0.3
CPT0087890004
Tumor
-0.3
CPT0124410004
Tumor
-0.3
CPT0226530004
Tumor
-0.3
CPT0126160004
Tumor
-0.3
CPT0008750003
Tumor
-0.3
CPT0094030003
Tumor
-0.3
CPT0246210004
Tumor
-0.3
CPT0236780005
Tumor
-0.3
CPT0246720003
Tumor
-0.4
CPT0236700005
Tumor
-0.4
CPT0108400003
Tumor
-0.4
CPT0187550004
Tumor
-0.4
CPT0078090004
Tumor
-0.4
CPT0197440004
Normal
-0.4
CPT0226570004
Tumor
-0.4
CPT0011520003
Tumor
-0.4
CPT0246940003
Tumor
-0.4
CPT0124980004
Tumor
-0.4
CPT0174800003
Normal
-0.4
CPT0241510004
Normal
-0.4
CPT0109300004
Tumor
-0.4
CPT0093980004
Tumor
-0.4
CPT0081260004
Tumor
-0.4
CPT0183450005
Tumor
-0.4
CPT0088260004
Tumor
-0.4
CPT0078030003
Normal
-0.4
CPT0108930003
Tumor
-0.4
CPT0238820005
Tumor
-0.5
CPT0226610004
Normal
-0.5
CPT0197420004
Tumor
-0.5
CPT0264150003
Tumor
-0.5
CPT0198420004
Tumor
-0.5
CPT0238040005
Tumor
-0.5
CPT0186040004
Tumor
-0.5
CPT0093930004
Tumor
-0.5
CPT0198910005
Tumor
-0.5
CPT0174700004
Tumor
-0.6
CPT0078000003
Tumor
-0.6
CPT0238530005
Tumor
-0.6
KoreanReference3
Tumor
-0.6
CPT0209310004
Tumor
-0.6
CPT0226680005
Tumor
-0.6
CPT0246990003
Tumor
-0.6
CPT0246260004
Tumor
-0.6
CPT0183750005
Tumor
-0.6
CPT0094940004
Tumor
-0.6
CPT0241500004
Tumor
-0.7
CPT0127270003
Tumor
-0.7
KoreanReference1
Tumor
-0.7
CPT0078250003
Tumor
-0.7
KoreanReference2
Tumor
-0.8
CPT0247050003
Normal
N/A
CPT0108410003
Normal
N/A
CPT0248320003
Normal
N/A
CPT0166650006
Tumor
N/A
CPT0224470004
Normal
N/A
C3L-01687-04
Normal
N/A
CPT0138890003
Normal
N/A
CPT0109110004
Tumor
N/A
WU-pooled sample
Tumor
N/A
CPT0014060003
Normal
N/A
CPT0109130003
Normal
N/A
CPT0138900004
Tumor
N/A
CPT0166680004
Normal
N/A
CPT0094760003
Normal
N/A
CPT0186050004
Normal
N/A
CPT0237290004
Normal
N/A
CPT0264180003
Normal
N/A
CPT0063990003
Normal
N/A
CPT0126200003
Normal
N/A
CPT0198730004
Normal
N/A
Show allShow less
PANCREATIC CANCER - Protein expressioni
A mouse-over function shows sample information and annotation data. Click on an image to view it in a full screen mode. Samples can be filtered based on level of antibody staining by selecting one or several of the following categories: high, medium, low and not detected. The assay and annotation is described here.
Note that samples used for immunohistochemistry by the Human Protein Atlas do not correspond to samples in the TCGA dataset.
Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
The Human Protein Atlas project is funded
