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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
Annotated protein expressioni
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA011753
Most normal cells displayed weak to moderate cytoplasmic staining. Cells in the granular layer of cerebellum displayed moderate nuclear positivity. Cells in lymphoid tissues and placenta were generally negative.
HPA017206
A majority of normal cells showed weak to moderate cytoplasmic staining. Subsets of cells in CNS and non-germinal center cells in lymphoid tissues were strongly stained. Squamous epithelia, breast, prostate, glial cell and cells in the female genital tract were negative.
CAB004347
Strong nuclear staining in combination with moderate cytoplasmic positivity was observed in granular layer of cerebellum, syncytiotrophoblasts of placenta and in glandular epithelia of the gastro-intestinal tract. Some neuronal cells were also distinctly stained. Remaining normal tissues were in general negative.
The Human Protein Atlas project is funded
