GENERAL INFORMATIONi
Gene namei ANK3
Synonyms
Gene descriptioni Ankyrin 3
Protein classi Cancer-related genes
Disease related genes
Human disease related genes
Plasma proteins
Potential drug targets
Transporters
Predicted locationi Intracellular
Protein evidence Evidence at protein level (all genes)
GENE INFORMATIONi
Chromosome 10
Cytoband q21.2
Chromosome location (bp) 60026298 - 60733490
Number of transcriptsi 24
Ensembl ENSG00000151150 (version 109)
Entrez gene 288
HGNC HGNC:494
UniProt Q12955 (UniProt - Evidence at protein level)
neXtProt NX_Q12955
GeneCards ANK3
Antibodypedia ANK3 antibodies


PROTEIN FUNCTION
Protein function (UniProt)i Membrane-cytoskeleton linker. May participate in the maintenance/targeting of ion channels and cell adhesion molecules at the nodes of Ranvier and axonal initial segments 1. In skeletal muscle, required for costamere localization of DMD and betaDAG1 (By similarity). Regulates KCNA1 channel activity in function of dietary Mg(2+) levels, and thereby contributes to the regulation of renal Mg(2+) reabsorption 2. Required for intracellular adhesion and junctional conductance in myocytes, potentially via stabilization of GJA1/CX43 protein abundance and promotion of PKP2, GJA1/CX43, and SCN5A/Nav1.5 localization to cell-cell junctions (By similarity). show less
Gene summary (Entrez)i Ankyrins are a family of proteins that are believed to link the integral membrane proteins to the underlying spectrin-actin cytoskeleton and play key roles in activities such as cell motility, activation, proliferation, contact, and the maintenance of specialized membrane domains. Multiple isoforms of ankyrin with different affinities for various target proteins are expressed in a tissue-specific, developmentally regulated manner. Most ankyrins are typically composed of three structural domains: an amino-terminal domain containing multiple ankyrin repeats; a central region with a highly conserved spectrin binding domain; and a carboxy-terminal regulatory domain which is the least conserved and subject to variation. Ankyrin 3 is an immunologically distinct gene product from ankyrins 1 and 2, and was originally found at the axonal initial segment and nodes of Ranvier of neurons in the central and peripheral nervous systems. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011] show less
PROTEIN INFORMATIONi
Splice variant SwissProt TrEMBL Protein class Gene ontology Length & mass Signal peptide
(predicted)		 Transmembrane regions
(predicted)
ANK3-201
ENSP00000280772
ENST00000280772
Q12955
[Direct mapping] Ankyrin-3
Show all
Transporters
   Accessory Factors Involved in Transport
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Mutated cancer genes
Disease related genes
Potential drug targets
Human disease related genes
   Other diseases
   Mental and behavioural disorders
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000281 [mitotic cytokinesis]
GO:0005200 [structural constituent of cytoskeleton]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005764 [lysosome]
GO:0005783 [endoplasmic reticulum]
GO:0005794 [Golgi apparatus]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005923 [bicellular tight junction]
GO:0007009 [plasma membrane organization]
GO:0007010 [cytoskeleton organization]
GO:0007165 [signal transduction]
GO:0007409 [axonogenesis]
GO:0007528 [neuromuscular junction development]
GO:0008092 [cytoskeletal protein binding]
GO:0008093 [cytoskeletal anchor activity]
GO:0009925 [basal plasma membrane]
GO:0009986 [cell surface]
GO:0010628 [positive regulation of gene expression]
GO:0010650 [positive regulation of cell communication by electrical coupling]
GO:0010765 [positive regulation of sodium ion transport]
GO:0010960 [magnesium ion homeostasis]
GO:0014704 [intercalated disc]
GO:0014731 [spectrin-associated cytoskeleton]
GO:0016020 [membrane]
GO:0016323 [basolateral plasma membrane]
GO:0016328 [lateral plasma membrane]
GO:0016529 [sarcoplasmic reticulum]
GO:0019228 [neuronal action potential]
GO:0030018 [Z disc]
GO:0030315 [T-tubule]
GO:0030424 [axon]
GO:0030425 [dendrite]
GO:0030507 [spectrin binding]
GO:0030674 [protein-macromolecule adaptor activity]
GO:0031594 [neuromuscular junction]
GO:0033268 [node of Ranvier]
GO:0034112 [positive regulation of homotypic cell-cell adhesion]
GO:0042383 [sarcolemma]
GO:0042995 [cell projection]
GO:0043001 [Golgi to plasma membrane protein transport]
GO:0043005 [neuron projection]
GO:0043034 [costamere]
GO:0043194 [axon initial segment]
GO:0043266 [regulation of potassium ion transport]
GO:0044325 [transmembrane transporter binding]
GO:0045184 [establishment of protein localization]
GO:0045202 [synapse]
GO:0045211 [postsynaptic membrane]
GO:0045296 [cadherin binding]
GO:0045838 [positive regulation of membrane potential]
GO:0051179 [localization]
GO:0071286 [cellular response to magnesium ion]
GO:0071709 [membrane assembly]
GO:0072659 [protein localization to plasma membrane]
GO:0072660 [maintenance of protein location in plasma membrane]
GO:0090314 [positive regulation of protein targeting to membrane]
GO:0099612 [protein localization to axon]
GO:1900827 [positive regulation of membrane depolarization during cardiac muscle cell action potential]
GO:1902260 [negative regulation of delayed rectifier potassium channel activity]
GO:2000651 [positive regulation of sodium ion transmembrane transporter activity]
GO:2001259 [positive regulation of cation channel activity]
Show all
 4377 aa
480.4 kDa 		No 0
ANK3-202
ENSP00000347436
ENST00000355288
Q12955
[Direct mapping] Ankyrin-3
Show all
Transporters
   Accessory Factors Involved in Transport
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Mutated cancer genes
Disease related genes
Potential drug targets
Human disease related genes
   Other diseases
   Mental and behavioural disorders
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000281 [mitotic cytokinesis]
GO:0005200 [structural constituent of cytoskeleton]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005764 [lysosome]
GO:0005783 [endoplasmic reticulum]
GO:0005794 [Golgi apparatus]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005923 [bicellular tight junction]
GO:0007009 [plasma membrane organization]
GO:0007010 [cytoskeleton organization]
GO:0007165 [signal transduction]
GO:0007409 [axonogenesis]
GO:0007528 [neuromuscular junction development]
GO:0008092 [cytoskeletal protein binding]
GO:0008093 [cytoskeletal anchor activity]
GO:0009925 [basal plasma membrane]
GO:0009986 [cell surface]
GO:0010628 [positive regulation of gene expression]
GO:0010650 [positive regulation of cell communication by electrical coupling]
GO:0010765 [positive regulation of sodium ion transport]
GO:0010960 [magnesium ion homeostasis]
GO:0014704 [intercalated disc]
GO:0014731 [spectrin-associated cytoskeleton]
GO:0016020 [membrane]
GO:0016323 [basolateral plasma membrane]
GO:0016328 [lateral plasma membrane]
GO:0016529 [sarcoplasmic reticulum]
GO:0019228 [neuronal action potential]
GO:0030018 [Z disc]
GO:0030315 [T-tubule]
GO:0030424 [axon]
GO:0030425 [dendrite]
GO:0030507 [spectrin binding]
GO:0030674 [protein-macromolecule adaptor activity]
GO:0031594 [neuromuscular junction]
GO:0033268 [node of Ranvier]
GO:0034112 [positive regulation of homotypic cell-cell adhesion]
GO:0042383 [sarcolemma]
GO:0042995 [cell projection]
GO:0043001 [Golgi to plasma membrane protein transport]
GO:0043005 [neuron projection]
GO:0043034 [costamere]
GO:0043194 [axon initial segment]
GO:0043266 [regulation of potassium ion transport]
GO:0044325 [transmembrane transporter binding]
GO:0045184 [establishment of protein localization]
GO:0045202 [synapse]
GO:0045211 [postsynaptic membrane]
GO:0045296 [cadherin binding]
GO:0045838 [positive regulation of membrane potential]
GO:0051179 [localization]
GO:0071286 [cellular response to magnesium ion]
GO:0071709 [membrane assembly]
GO:0072659 [protein localization to plasma membrane]
GO:0072660 [maintenance of protein location in plasma membrane]
GO:0090314 [positive regulation of protein targeting to membrane]
GO:0099612 [protein localization to axon]
GO:1900827 [positive regulation of membrane depolarization during cardiac muscle cell action potential]
GO:1902260 [negative regulation of delayed rectifier potassium channel activity]
GO:2000651 [positive regulation of sodium ion transmembrane transporter activity]
GO:2001259 [positive regulation of cation channel activity]
Show all
 1001 aa
111.1 kDa 		No 0
ANK3-203
ENSP00000362921
ENST00000373815
B1AQT1
[Direct mapping] Ankyrin-3
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Cancer-related genes
   Mutated cancer genes
Human disease related genes
   Other diseases
   Mental and behavioural disorders
Protein evidence (Ezkurdia et al 2014)
Show all
 195 aa
21.5 kDa 		No 0
ANK3-204
ENSP00000362926
ENST00000373820
H0Y3A4
[Direct mapping] Ankyrin-3
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Cancer-related genes
   Mutated cancer genes
Human disease related genes
   Other diseases
   Mental and behavioural disorders
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005886 [plasma membrane]
GO:0007165 [signal transduction]
Show all
 459 aa
50.7 kDa 		No 0
ANK3-205
ENSP00000362933
ENST00000373827
Q12955
[Direct mapping] Ankyrin-3
Show all
Transporters
   Accessory Factors Involved in Transport
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Mutated cancer genes
Disease related genes
Potential drug targets
Human disease related genes
   Other diseases
   Mental and behavioural disorders
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000281 [mitotic cytokinesis]
GO:0005200 [structural constituent of cytoskeleton]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005764 [lysosome]
GO:0005783 [endoplasmic reticulum]
GO:0005794 [Golgi apparatus]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005923 [bicellular tight junction]
GO:0007009 [plasma membrane organization]
GO:0007010 [cytoskeleton organization]
GO:0007165 [signal transduction]
GO:0007409 [axonogenesis]
GO:0007528 [neuromuscular junction development]
GO:0008092 [cytoskeletal protein binding]
GO:0008093 [cytoskeletal anchor activity]
GO:0009925 [basal plasma membrane]
GO:0009986 [cell surface]
GO:0010628 [positive regulation of gene expression]
GO:0010650 [positive regulation of cell communication by electrical coupling]
GO:0010765 [positive regulation of sodium ion transport]
GO:0010960 [magnesium ion homeostasis]
GO:0014704 [intercalated disc]
GO:0014731 [spectrin-associated cytoskeleton]
GO:0016020 [membrane]
GO:0016323 [basolateral plasma membrane]
GO:0016328 [lateral plasma membrane]
GO:0016529 [sarcoplasmic reticulum]
GO:0019228 [neuronal action potential]
GO:0030018 [Z disc]
GO:0030315 [T-tubule]
GO:0030424 [axon]
GO:0030425 [dendrite]
GO:0030507 [spectrin binding]
GO:0030674 [protein-macromolecule adaptor activity]
GO:0031594 [neuromuscular junction]
GO:0033268 [node of Ranvier]
GO:0034112 [positive regulation of homotypic cell-cell adhesion]
GO:0042383 [sarcolemma]
GO:0042995 [cell projection]
GO:0043001 [Golgi to plasma membrane protein transport]
GO:0043005 [neuron projection]
GO:0043034 [costamere]
GO:0043194 [axon initial segment]
GO:0043266 [regulation of potassium ion transport]
GO:0044325 [transmembrane transporter binding]
GO:0045184 [establishment of protein localization]
GO:0045202 [synapse]
GO:0045211 [postsynaptic membrane]
GO:0045296 [cadherin binding]
GO:0045838 [positive regulation of membrane potential]
GO:0051179 [localization]
GO:0071286 [cellular response to magnesium ion]
GO:0071709 [membrane assembly]
GO:0072659 [protein localization to plasma membrane]
GO:0072660 [maintenance of protein location in plasma membrane]
GO:0090314 [positive regulation of protein targeting to membrane]
GO:0099612 [protein localization to axon]
GO:1900827 [positive regulation of membrane depolarization during cardiac muscle cell action potential]
GO:1902260 [negative regulation of delayed rectifier potassium channel activity]
GO:2000651 [positive regulation of sodium ion transmembrane transporter activity]
GO:2001259 [positive regulation of cation channel activity]
Show all
 1861 aa
202.6 kDa 		No 0
ANK3-206
ENSP00000480249
ENST00000459732
A0A087WWI5
[Direct mapping] Ankyrin-3
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Cancer-related genes
   Mutated cancer genes
Human disease related genes
   Other diseases
   Mental and behavioural disorders
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0007165 [signal transduction]
Show all
 96 aa
10.7 kDa 		No 0
ANK3-207
ENSP00000426690
ENST00000460468
D6RF31
[Direct mapping] Ankyrin-3
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Cancer-related genes
   Mutated cancer genes
Human disease related genes
   Other diseases
   Mental and behavioural disorders
Protein evidence (Ezkurdia et al 2014)
Show all
 86 aa
9.6 kDa 		No 0
ANK3-209
ENSP00000423968
ENST00000467420
H0Y9E9
[Direct mapping] Ankyrin-3
Show all
   SCAMPI predicted membrane proteins
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Cancer-related genes
   Mutated cancer genes
Human disease related genes
   Other diseases
   Mental and behavioural disorders
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0007165 [signal transduction]
Show all
 1792 aa
195.9 kDa 		No 0
ANK3-211
ENSP00000422657
ENST00000474360
H0Y8Z4
[Direct mapping] Ankyrin-3
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Cancer-related genes
   Mutated cancer genes
Human disease related genes
   Other diseases
   Mental and behavioural disorders
Protein evidence (Ezkurdia et al 2014)
Show all
 114 aa
12.8 kDa 		No 0
ANK3-213
ENSP00000483483
ENST00000486349
A0A087X0L3
[Direct mapping] Ankyrin-3
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Cancer-related genes
   Mutated cancer genes
Human disease related genes
   Other diseases
   Mental and behavioural disorders
Protein evidence (Ezkurdia et al 2014)
Show all
 63 aa
6.7 kDa 		No 0
ANK3-215
ENSP00000423057
ENST00000502769
H0Y951
[Direct mapping] Ankyrin-3
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Cancer-related genes
   Mutated cancer genes
Human disease related genes
   Other diseases
   Mental and behavioural disorders
Protein evidence (Ezkurdia et al 2014)
Show all
 166 aa
18.1 kDa 		No 0
ANK3-216
ENSP00000425236
ENST00000503366
Q12955
[Direct mapping] Ankyrin-3
Show all
Transporters
   Accessory Factors Involved in Transport
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Mutated cancer genes
Disease related genes
Potential drug targets
Human disease related genes
   Other diseases
   Mental and behavioural disorders
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000281 [mitotic cytokinesis]
GO:0005200 [structural constituent of cytoskeleton]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005764 [lysosome]
GO:0005783 [endoplasmic reticulum]
GO:0005794 [Golgi apparatus]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005923 [bicellular tight junction]
GO:0007009 [plasma membrane organization]
GO:0007010 [cytoskeleton organization]
GO:0007165 [signal transduction]
GO:0007409 [axonogenesis]
GO:0007528 [neuromuscular junction development]
GO:0008092 [cytoskeletal protein binding]
GO:0008093 [cytoskeletal anchor activity]
GO:0009925 [basal plasma membrane]
GO:0009986 [cell surface]
GO:0010628 [positive regulation of gene expression]
GO:0010650 [positive regulation of cell communication by electrical coupling]
GO:0010765 [positive regulation of sodium ion transport]
GO:0010960 [magnesium ion homeostasis]
GO:0014704 [intercalated disc]
GO:0014731 [spectrin-associated cytoskeleton]
GO:0016020 [membrane]
GO:0016323 [basolateral plasma membrane]
GO:0016328 [lateral plasma membrane]
GO:0016529 [sarcoplasmic reticulum]
GO:0019228 [neuronal action potential]
GO:0030018 [Z disc]
GO:0030315 [T-tubule]
GO:0030424 [axon]
GO:0030425 [dendrite]
GO:0030507 [spectrin binding]
GO:0030674 [protein-macromolecule adaptor activity]
GO:0031594 [neuromuscular junction]
GO:0033268 [node of Ranvier]
GO:0034112 [positive regulation of homotypic cell-cell adhesion]
GO:0042383 [sarcolemma]
GO:0042995 [cell projection]
GO:0043001 [Golgi to plasma membrane protein transport]
GO:0043005 [neuron projection]
GO:0043034 [costamere]
GO:0043194 [axon initial segment]
GO:0043266 [regulation of potassium ion transport]
GO:0044325 [transmembrane transporter binding]
GO:0045184 [establishment of protein localization]
GO:0045202 [synapse]
GO:0045211 [postsynaptic membrane]
GO:0045296 [cadherin binding]
GO:0045838 [positive regulation of membrane potential]
GO:0051179 [localization]
GO:0071286 [cellular response to magnesium ion]
GO:0071709 [membrane assembly]
GO:0072659 [protein localization to plasma membrane]
GO:0072660 [maintenance of protein location in plasma membrane]
GO:0090314 [positive regulation of protein targeting to membrane]
GO:0099612 [protein localization to axon]
GO:1900827 [positive regulation of membrane depolarization during cardiac muscle cell action potential]
GO:1902260 [negative regulation of delayed rectifier potassium channel activity]
GO:2000651 [positive regulation of sodium ion transmembrane transporter activity]
GO:2001259 [positive regulation of cation channel activity]
Show all
 1868 aa
204.1 kDa 		No 0
ANK3-217
ENSP00000426011
ENST00000503925
D6RHY3
[Direct mapping] Ankyrin-3
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Cancer-related genes
   Mutated cancer genes
Human disease related genes
   Other diseases
   Mental and behavioural disorders
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
Show all
 273 aa
29.1 kDa 		No 0
ANK3-218
ENSP00000422506
ENST00000506635
D6RBY7
[Direct mapping] Ankyrin-3
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Cancer-related genes
   Mutated cancer genes
Human disease related genes
   Other diseases
   Mental and behavioural disorders
Protein evidence (Ezkurdia et al 2014)
Show all
 72 aa
8 kDa 		No 0
ANK3-221
ENSP00000426258
ENST00000511043
H0YA66
[Direct mapping] Ankyrin-3
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Cancer-related genes
   Mutated cancer genes
Human disease related genes
   Other diseases
   Mental and behavioural disorders
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0007165 [signal transduction]
Show all
 187 aa
20.8 kDa 		No 0
ANK3-222
ENSP00000426582
ENST00000513049
D6RFK6
[Direct mapping] Ankyrin-3
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Cancer-related genes
   Mutated cancer genes
Human disease related genes
   Other diseases
   Mental and behavioural disorders
Protein evidence (Ezkurdia et al 2014)
Show all
 159 aa
17.8 kDa 		No 0
ANK3-223
ENSP00000427121
ENST00000514197
H0YAH5
[Direct mapping] Ankyrin-3
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Cancer-related genes
   Mutated cancer genes
Human disease related genes
   Other diseases
   Mental and behavioural disorders
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0007165 [signal transduction]
Show all
 217 aa
23.7 kDa 		No 0
ANK3-224
ENSP00000477827
ENST00000610321
A0A087WTF3
[Direct mapping] Ankyrin-3
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Cancer-related genes
   Mutated cancer genes
Human disease related genes
   Other diseases
   Mental and behavioural disorders
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005886 [plasma membrane]
GO:0007165 [signal transduction]
GO:0016020 [membrane]
Show all
 1643 aa
179.5 kDa 		No 0
ANK3-225
ENSP00000479337
ENST00000610901
A0A087WVC2
[Direct mapping] Ankyrin-3
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Cancer-related genes
   Mutated cancer genes
Human disease related genes
   Other diseases
   Mental and behavioural disorders
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0007165 [signal transduction]
Show all
 322 aa
36 kDa 		No 0
ANK3-226
ENSP00000481611
ENST00000612776
A0A087WY90
[Direct mapping] Ankyrin-3
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Cancer-related genes
   Mutated cancer genes
Human disease related genes
   Other diseases
   Mental and behavioural disorders
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005886 [plasma membrane]
Show all
 178 aa
19.4 kDa 		No 0
ANK3-227
ENSP00000477814
ENST00000613207
A0A087WTE8
[Direct mapping] Ankyrin-3
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Cancer-related genes
   Mutated cancer genes
Human disease related genes
   Other diseases
   Mental and behavioural disorders
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0007165 [signal transduction]
Show all
 241 aa
26.9 kDa 		No 0
ANK3-228
ENSP00000482401
ENST00000616444
A0A087WZ65
[Direct mapping] Ankyrin-3
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Cancer-related genes
   Mutated cancer genes
Human disease related genes
   Other diseases
   Mental and behavioural disorders
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005886 [plasma membrane]
GO:0007165 [signal transduction]
GO:0016020 [membrane]
Show all
 973 aa
108.6 kDa 		No 0
ANK3-229
ENSP00000480745
ENST00000617800
A0A087WX55
[Direct mapping] Ankyrin-3
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Cancer-related genes
   Mutated cancer genes
Human disease related genes
   Other diseases
   Mental and behavioural disorders
Protein evidence (Ezkurdia et al 2014)
Show all
 175 aa
19.7 kDa 		No 0
ANK3-230
ENSP00000482307
ENST00000618080
A0A087WZ26
[Direct mapping] Ankyrin-3
Show all
   SCAMPI predicted membrane proteins
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Cancer-related genes
   Mutated cancer genes
Human disease related genes
   Other diseases
   Mental and behavioural disorders
Protein evidence (Ezkurdia et al 2014)
Show all
 201 aa
22.2 kDa 		No 0

Contact

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