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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
Annotated protein expressioni
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA039835
Strong cytoplasmic positivity was observed in peripheral nerves and neuropil in the CNS. Subsets of glial cells, cells in white pulp of spleen and muscle cells showed weak to moderate staining. Thyroid, adrenal cortex, keratinocytes, gastric chief cells and pancreatic ducts showed moderate to strong membranous staining. Remaining normal tissues were in general negative.
CAB000142
Neuropil in the CNS showed strong immunoreactivity. Strong cytoplasmic and membranous staining was observed in heart, pancreatic islets, Leydig cells, gastric chief cells, thyroid and the adrenal gland. Cytoplasmic positivity was observed in smooth muscle and subsets of cells in breast. Remaining normal cells were generally negative.
CAB018071
Neuropil in the CNS and peripheral nerves were distinctly stained. Cells in the molecular and granular layer of cerebellum showed moderate cytoplasmic positivity. The adrenal gland and gastric chief cells displayed membranous staining. Remaining normal tissues were mainly negative.
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