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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
Annotated protein expressioni
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA054026
Normal tissues displayed moderate to strong cytoplasmic staining with additional membranous or nuclear positivity in several tissues. Purkinje cells, adipocytes, liver, exocrine pancreas, parathyroid and seminal vesicle were negative.
CAB010823
Macrophages, gastric glandular cells, pancreatic islet cells as well as subsets of glial cells and lymphoid cells showed strong cytoplasmic staining. Moderate immunoreactivity was observed in respiratory epithelium, fallopian tube, kidney and Langerhans cells in skin. Most remaining normal tissues were weakly stained or negative.
CAB016728
Most of the normal tissues displayed moderate to strong cytoplasmic positivity occasionally accompanied with membranous staining. Additionally strong nuclear staining was observed in the spleen and glial cells of CNS. Macrophages were strongly stained e.g. in liver, skin and lung. Liver, endocrine glands except islet cells, testicular and neuronal cells were weakly stained or negative.
CAB036009
Moderate cytoplasmic positivity was observed in bone marrow, macrophages, a subset of glial cells, kidney, islet cells and ducts in salivary gland. Endometrial glands were strongly stained. Most remaining normal tissues were weakly stained or negative.