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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
Annotated protein expressioni
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA052474
Neuronal cells in CNS and a subset of renal tubules showed strong cytoplasmic positivity. Superficial cells in squamous epithelia displayed moderate staining. Other normal tissues were negative.
HPA052484
Neuronal cells displayed strong cytoplasmic staining. Purkinje cells, small intestine, fraction of skeletal muscle cells, thyroid gland, adrenal gland, heart myocytes and Leydig cells showed weak to moderate staining. Remaining normal tissues were negative.
HPA053767
Strong membranous and/or cytoplasmic positivity was observed in most normal tissues. Neuronal and glial cells displayed moderate cytoplasmic and nuclear staining. Placental trophoblastic cells and skeletal myocytes were negative.
CAB037216
Most normal tissues exhibited weak to moderate nuclear and/or cytoplasmic immunoreactivity. Gall bladder, salivary and uterine gland showed additional membranous positivity. Thyroid gland and neuronal cells of lateral ventricles were strongly stained. Appendix, liver cells, glial cells and the lymphoid tissues were negative.
The Human Protein Atlas project is funded
