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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
No data
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
2.6
nTPM
HPA Brain:
5.3
nTPM
GTEx:
2.6
nTPM
Pig:
9.0
nTPM
Mouse:
1.6
nTPM
Allen mouse:
0.1
Expression energy
MIDBRAIN - Annotated protein expression
Pending normal tissue analysis
MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
5.3
Sample id
Sample description
nTPM
Cuneiform nucleus nTPM: 2.5
1827
Male, age 72, unknown
5.4
2828
Female, age 72, unknown
4.6
2019
Male, age 18, unknown
4.4
2219
Male, age 76, both hemispheres
2.6
2666
Male, age 74, left hemisphere
2.3
2411
Female, age 72, unknown
2.2
2586
Male, age 75, left hemisphere
1.6
1833
Male, age 53, unknown
0.9
1870
Female, age 42, unknown
0.8
1830
Male, age 51, unknown
0.7
Dorsal raphe nucleus nTPM: 0.9
2298
Female, age 72, unknown
1.7
1828
Male, age 53, unknown
1.1
2750
Male, age 76, both hemispheres
0.8
2016
Female, age 72, unknown
0.5
2047
Male, age 72, unknown
0.2
Inferior colliculus nTPM: 1.7
2097
Female, age 72, unknown
3.3
1890
Male, age 53, unknown
2.1
1848
Female, age 42, unknown
1.3
2849
Male, age 72, unknown
0.0
Median raphe nucleus nTPM: 1.0
2220
Male, age 76, midline
1.0
Periaquaductal grey, anterior nTPM: 2.5
1795
Male, age 51, unknown
4.6
2502
Female, age 75, unknown
1.5
1947
Male, age 18, unknown
1.4
Periaquaductal grey, dorsal nTPM: 1.5
1831
Male, age 72, unknown
3.3
2464
Female, age 72, unknown
1.4
2850
Male, age 76, both hemispheres
0.8
1840
Male, age 53, unknown
0.4
Periaquaductal grey, lateral nTPM: 1.5
2053
Male, age 18, unknown
2.2
2272
Male, age 74, both hemispheres
1.7
2140
Male, age 76, both hemispheres
0.7
Pretectal area nTPM: 5.3
1816
Male, age 51, unknown
13.6
1944
Female, age 72, unknown
11.1
1815
Male, age 53, unknown
8.1
1817
Female, age 42, unknown
7.6
2007
Male, age 72, unknown
7.5
2667
Female, age 75, unknown
3.0
2273
Male, age 74, both hemispheres
1.7
2224
Female, age 72, unknown
1.6
2407
Male, age 75, both hemispheres
1.5
2316
Male, age 76, right hemisphere
1.3
2825
Male, age 18, unknown
0.9
Red nucleus nTPM: 2.2
2785
Male, age 18, unknown
4.4
1904
Male, age 53, unknown
3.0
1954
Female, age 42, unknown
2.7
1821
Female, age 72, unknown
2.6
2503
Female, age 72, unknown
2.5
1865
Male, age 51, unknown
2.3
2823
Male, age 76, right hemisphere
2.0
2584
Male, age 75, left hemisphere
1.7
2588
Male, age 74, left hemisphere
1.6
2725
Female, age 75, unknown
1.4
2769
Male, age 72, unknown
1.3
2227
Male, age 72, unknown
1.1
Substantia nigra nTPM: 4.5
1916
Female, age 42, unknown
9.5
1851
Male, age 51, unknown
6.6
1889
Female, age 72, unknown
6.2
2665
Male, age 74, both hemispheres
4.2
2409
Female, age 72, unknown
4.1
1941
Male, age 53, unknown
3.9
2241
Male, age 72, unknown
3.4
2583
Male, age 75, right hemisphere
3.1
2590
Female, age 75, unknown
2.2
2699
Male, age 18, unknown
2.0
Superior colliculus nTPM: 4.8
2668
Female, age 75, unknown
13.8
2087
Female, age 72, unknown
9.5
2261
Male, age 18, unknown
6.0
1796
Male, age 53, unknown
5.7
1995
Male, age 72, unknown
4.2
1913
Female, age 42, unknown
3.9
1895
Male, age 76, right hemisphere
1.5
2664
Male, age 75, both hemispheres
1.4
2587
Male, age 74, left hemisphere
1.3
1839
Male, age 51, unknown
0.7
Ventral tegmental area nTPM: 3.0
2410
Female, age 72, unknown
6.8
2218
Male, age 76, both hemispheres
5.2
1915
Female, age 42, unknown
3.9
1942
Male, age 51, unknown
1.0
2021
Male, age 53, unknown
0.7
2223
Female, age 72, unknown
0.4
MIDBRAIN - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
2.6
GTEx sample id
Sample description
nTPM
Brain - Substantia nigra Average nTPM: 2.6
Samples: 139
Max nTPM: 15.0
Min nTPM: 0.0
Std nTPM: 2.6
Median nTPM: 1.5
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
1.6
Mouse sample
Sample description
nTPM
Midbrain nTPM: 1.6
Samples: 4
Max nTPM: 1.9
Min nTPM: 1.3
Sample A
Male
1.9
Sample B
Male
1.7
Sample C
Female
1.4
Sample D
Female
1.3
MIDBRAIN - Allen Mouse ISHi
In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.
Max subtype Expression energyi
Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.
The Human Protein Atlas project is funded
