We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene namei
Official gene symbol, which is typically a short form of the gene name, according to HGNC.
Electron transfer flavoprotein subunit beta lysine methyltransferase
Predicted locationi
All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions.
Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached.
Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s).
The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location.
Gene information from Ensembl and Entrez, as well as links to available gene identifiers are displayed here. Information was retrieved from Ensembl if not indicated otherwise.
Chromosome
12
Cytoband
p11.21
Chromosome location (bp)
31647160 - 31673114
Number of transcriptsi
Number of protein-coding transcripts from the gene as defined by Ensembl.
Useful information about the protein provided by UniProt.
Protein-lysine methyltransferase that selectively trimethylates the flavoprotein ETFB in mitochondria 1,2. Thereby, may negatively regulate the function of ETFB in electron transfer from Acyl-CoA dehydrogenases to the main respiratory chain 3....show less
Molecular function (UniProt)i
Keywords assigned by UniProt to proteins due to their particular molecular function.
Methyltransferase, Transferase
Gene summary (Entrez)i
Useful information about the gene from Entrez
Enables heat shock protein binding activity and protein-lysine N-methyltransferase activity. Involved in negative regulation of electron transfer activity; negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase; and peptidyl-lysine trimethylation. Located in mitochondrial matrix. Part of protein-containing complex. [provided by Alliance of Genome Resources, Apr 2022]...show less
PROTEIN INFORMATIONi
The protein information section displays alternative protein-coding transcripts (splice variants) encoded by this gene according to the Ensembl database.
The Splice variant identifier links to the Ensembl website protein summary for the selected splice variant. The data in the Swissprot and TrEMBL columns links to corresponding pages in the UniProt database.
The protein classes assigned to this protein are shown if expanding the data in the protein class column. Parent protein classes are in bold font and subclasses are listed under the parent class.
The length of the protein (amino acid residues according to Ensembl), molecular mass (kDalton), predicted signal peptide and number of predicted transmembrane region(s) according to in-house majority decision methods based on sets of predictors are also reported.
Q8IXQ9 [Direct mapping] Electron transfer flavoprotein beta subunit lysine methyltransferase
Show all
SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Kim et al 2014)
Show all
GO:0005737[cytoplasm] GO:0005739[mitochondrion] GO:0005759[mitochondrial matrix] GO:0006479[protein methylation] GO:0008168[methyltransferase activity] GO:0008276[protein methyltransferase activity] GO:0016279[protein-lysine N-methyltransferase activity] GO:0016740[transferase activity] GO:0018022[peptidyl-lysine methylation] GO:0018023[peptidyl-lysine trimethylation] GO:0031072[heat shock protein binding] GO:0032259[methylation] GO:0032991[protein-containing complex] GO:1904733[negative regulation of electron transfer activity] GO:1904736[negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase]
Q8IXQ9 [Direct mapping] Electron transfer flavoprotein beta subunit lysine methyltransferase
Show all
SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Kim et al 2014)
Show all
GO:0005737[cytoplasm] GO:0005739[mitochondrion] GO:0005759[mitochondrial matrix] GO:0006479[protein methylation] GO:0008168[methyltransferase activity] GO:0008276[protein methyltransferase activity] GO:0016279[protein-lysine N-methyltransferase activity] GO:0016740[transferase activity] GO:0018022[peptidyl-lysine methylation] GO:0018023[peptidyl-lysine trimethylation] GO:0031072[heat shock protein binding] GO:0032259[methylation] GO:0032991[protein-containing complex] GO:1904733[negative regulation of electron transfer activity] GO:1904736[negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase]
Q8IXQ9 [Direct mapping] Electron transfer flavoprotein beta subunit lysine methyltransferase
Show all
SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Kim et al 2014)
Show all
GO:0005737[cytoplasm] GO:0005739[mitochondrion] GO:0005759[mitochondrial matrix] GO:0006479[protein methylation] GO:0008168[methyltransferase activity] GO:0008276[protein methyltransferase activity] GO:0016279[protein-lysine N-methyltransferase activity] GO:0016740[transferase activity] GO:0018022[peptidyl-lysine methylation] GO:0018023[peptidyl-lysine trimethylation] GO:0031072[heat shock protein binding] GO:0032259[methylation] GO:0032991[protein-containing complex] GO:1904733[negative regulation of electron transfer activity] GO:1904736[negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase]
Q8IXQ9 [Direct mapping] Electron transfer flavoprotein beta subunit lysine methyltransferase
Show all
SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Mapped to neXtProt neXtProt - Evidence at protein level
Show all
GO:0005737[cytoplasm] GO:0005739[mitochondrion] GO:0005759[mitochondrial matrix] GO:0006479[protein methylation] GO:0008168[methyltransferase activity] GO:0008276[protein methyltransferase activity] GO:0016279[protein-lysine N-methyltransferase activity] GO:0016740[transferase activity] GO:0018022[peptidyl-lysine methylation] GO:0018023[peptidyl-lysine trimethylation] GO:0031072[heat shock protein binding] GO:0032259[methylation] GO:0032991[protein-containing complex] GO:1904733[negative regulation of electron transfer activity] GO:1904736[negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase]
The Human Protein Atlas project is funded
